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https://www.readbyqxmd.com/read/29750110/non-specific-interstitial-pneumonia-associated-with-clinically-amyopathic-dermatomyositis-showing-crazy-paving-appearance-on-thin-section-lung-ct
#1
Yuya Aono, Tatsuru Eifuku, Tomohiro Uto, Jun Sato, Shiro Imokawa, Takafumi Suda
The "crazy paving" appearance consists of ground-glass opacity superimposed on a network of linear opacities on thin-section computed tomography (CT) images of the lung. This finding has been described in a variety of diseases but is extremely rare in patients with non-specific interstitial pneumonia (NSIP). We describe a 45-year-old woman with biopsy-proven NSIP associated with clinically amyopathic dermatomyositis that showed a "crazy paving" appearance on thin-section CT of the lung. Clinicians should include NSIP in the differential diagnosis in patients presenting with "crazy paving" appearance on thin-section chest CT...
July 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29709938/a-case-of-pulmonary-alveolar-proteinosis-with-ulcerative-colitis
#2
Noriho Sakamoto, Shota Nakashima, Hiroshi Ishimoto, Tomoyuki Kakugawa, Atsuko Hara, Hirokazu Yura, Takuto Miyamura, Seiko Nakamichi, Yasushi Obase, Yuji Ishimatsu, Hiroshi Mukae
A 65-year-old Japanese man was referred to our hospital for the further assessment of cough and dyspnea. He had a history of ulcerative colitis for which he was receiving treatment. Chest computed tomography showed a crazy-paving pattern. His bronchoalveolar lavage fluid had a milky appearance, and a transbronchial lung biopsy specimen revealed acellular periodic acid-Schiff stain-positive bodies. The serum anti-GM-CSF antibody titer was elevated. The diagnosis was autoimmune pulmonary alveolar proteinosis (PAP)...
April 27, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29592982/pulmonary-alveolar-proteinosis-following-cryptococcal-meningitis-a-possible-cause
#3
Sarah Demir, Nader Chebib, Francoise Thivolet-Bejui, Vincent Cottin
Autoimmune pulmonary alveolar proteinosis (PAP) is a rare interstitial lung disease characterised by the presence of granulocyte macrophage colony-stimulating factor (GM-CSF) autoantibodies. A man with no history of infection developed cryptococcal meningitis and a right parahilar cryptococcal mass. Antifungal treatment led to infection control, although there was presence of neurological sequelae. After 3 years, thoracic CT revealed bilateral ground glass opacities and a crazy paving pattern. Transparietal needle biopsy showed proteinaceous alveolar deposits, confirming the diagnosis of PAP...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29340494/niemann-pick-disease-type-b-hrct-assessment-of-pulmonary-involvement
#4
Heloisa Maria Pereira Freitas, Alexandre Dias Mançano, Rosana Souza Rodrigues, Bruno Hochhegger, Pedro Paulo Teixeira E Silva Torres, Dante Escuissato, Cesar Augusto Araujo Neto, Edson Marchiori
OBJECTIVE: To analyze HRCT findings in patients with Niemann-Pick disease (NPD) type B, in order to determine the frequency of HRCT patterns and their distribution in the lung parenchyma, as well as the most common clinical characteristics. METHODS: We studied 13 patients (3 males and 10 females) aged 5 to 56 years. HRCT images were independently evaluated by two observers, and disagreements were resolved by consensus. The inclusion criteria were presence of abnormal HRCT findings and diagnosis of NPD type B confirmed by histopathological examination of a bone marrow, lung, or liver biopsy specimen...
November 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29095306/clinical-features-of-secondary-pulmonary-alveolar-proteinosis-associated-with-myelodysplastic-syndrome-two-case-reports
#5
Yin Liu, Lu Lu Chen, Yu Ying Qiu, Yong Long Xiao, Hou Rong Cai
RATIONALE: Pulmonary alveolar proteinosis (PAP) is a rare lung disorder characterized by the abnormal accumulation of alveolar surfactant protein in alveolar spaces. Secondary PAP can result from myelodysplastic syndrome (MDS). PATIENT CONCERNS: But most reports described a single case; here we reported 2 cases of PAP secondary to MDS. One case developed secondary PAP at the same time as MDS, and the other developed during the course of MDS. DIAGNOSES: The diagnosis of PAP was made by bronchoalveolar lavage and based on the identification of periodic acid-Schiff-positive proteinaceous material...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29021953/bilateral-lung-disease-extensive-and-diffuse-diagnosis-of-pulmonary-alveolar-proteinosis-by-bronchoscopic-cryobiopsy
#6
Sebastián Gando, Roberto Duré, Damián Violi, Bibiana Vazquez, Gonzalo Labarca, Sebastián Fernandez-Bussy
Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the intra-alveolar accumulation of a proteinaceous phospholipid-laden material called surfactant. Clinically, this disease should be suspected with respiratory failure in association with a crazy paving pattern on high-resolution chest computed tomography. We report a 24-year-old gentleman who was referred to us for a history of respiratory failure, treatment with invasive ventilation and tracheostomy. His blood exams and biochemistry were normal...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28966213/elevated-serum-anti-gm-csf-antibodies-before-the-onset-of-autoimmune-pulmonary-alveolar-proteinosis-in-a-patient-with-sarcoidosis-and-systemic-sclerosis
#7
Mari Yamasue, Shin-Ichi Nureki, Yuko Usagawa, Tomoko Ono, Hiroyuki Matsumoto, Takamasa Kan, Jun-Ichi Kadota
Pulmonary alveolar proteinosis (PAP) is characterized by the accumulation of periodic acid-schiff stain-positive lipoproteinaceous materials in the alveolar space due to impaired surfactant clearance by alveolar macrophage. Autoimmune PAP is the most common form of PAP, but rarely accompanies collagen disease or sarcoidosis. We report here a rare case of autoimmune PAP preceded by systemic sclerosis and sarcoidosis. A 64-year-old woman was admitted to our hospital for blurred vision, muscle weakness of extremities, Raynaud's phenomenon, and exertional dyspnea...
September 2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28914826/pulmonary-alveolar-proteinosis-a-case-report
#8
Luis Alberto Concepción-Urteaga, Luis Alejandro Rodríguez-Hidalgo, Jorge Luis Cornejo-Portella, Oscar Neri Alquizar-Horna, Daniel Anderson Aguilar-Villanueva, Marcio José Concepción-Zavaleta, Mario Gustavo Azañero-Luján
INTRODUCTION: Pulmonary alveolar proteinosis is a rare, diffuse interstitial lung disease, characterized by alveolar obstruction due to the accumulation of pulmonary surfactant. CLINICAL PRESENTATION: A 30-year-old male with progressively worsening dyspnea and non-productive cough for one year. He was a sugar cane plantation worker and had prior recurrent respiratory infections. Physical exam revealed cyanosis, and bilateral coarse and fine rales. Chest computed tomography showed diffuse crazy paving pattern...
September 14, 2017: Medwave
https://www.readbyqxmd.com/read/28883249/pneumonitis-with-diffuse-alveolar-hemorrhage-induced-by-sho-seiryu-to
#9
Kazuo Tsuchiya, Mikio Toyoshima, Takafumi Suda
A 78-year-old man presented with acute-onset fever and dyspnea. He had been taking Sho-seiryu-to for allergic rhinitis. A chest radiograph showed diffuse bilateral ground-glass opacities with subpleural sparing, crazy-paving pattern, and traction bronchiectasis. The patient's bronchoalveolar lavage fluid was bloody and transbronchial lung biopsy specimens showed alveolitis, organizing pneumonia, and type 2 alveolar epithelial cell proliferation. There were no clinical and laboratory findings suggestive of respiratory tract infection or connective tissue disease...
October 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28670025/high-resolution-computed-tomography-findings-in-eight-patients-with-hantavirus-pulmonary-syndrome
#10
Diego de Lacerda Barbosa, Bruno Hochhegger, Arthur Soares Souza, Gláucia Zanetti, Dante Luiz Escuissato, Gustavo de Souza Portes Meirelles, Marcelo Buarque de Gusmão Funari, Edson Marchiori
OBJECTIVE: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). MATERIALS AND METHODS: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus...
May 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28507378/case-series-of-rare-interstitial-lung-disease-ild
#11
Naveed Haroon Rashid, Saba Farooq, Mohammad Ahmed, Ali Bin Sarwar Zubairi
Pulmonary alveolar proteinosis (PAP) is a rare lung disease where periodic acid Schiff (PAS)-positive eosinophilic material accumulates in the alveoli of the lungs. Here we describe two cases of young males who presented with dynpnoea and weight loss. The HRCT scan of the chest in both cases showed the typical "crazy-paving" pattern and lung biopsies confirmed the diagnosis of PAP. They showed remarkable symptomatic improvement with therapeutic whole lung lavage.
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28469724/simultaneous-presentation-of-two-noninflammatory-lung-diseases-in-an-hiv-infected-patient
#12
Rafael Martínez-Girón, Santiago Martínez-Torre
The simultaneous presentation of two noninflammatory pulmonary diseases, pulmonary alveolar proteinosis and Kaposi's sarcoma (Ks), in an HIV-infected patient, is described. A 29-year-old black race patient was admitted to the hospital because of general malaise, weight loss, dyspnea, chest pain, and cough with hemoptoic expectoration. Chest X-rays revealed a patchy bilateral alveolar pattern with a tendency toward the formation of condensations. The serological test revealed HIV positivity (CD4 counts of 393 cells/mm(3))...
April 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28396784/crazy-paving-pattern
#13
Rajanshu Verma, Mamoun Abdoh
Crazy paving pattern is the name given to characteristic polygonal pattern of interlobular thickening on computed tomography (CT scan) of the lung, which results from accumulation of collagen, interstitial fluid, cell, or other pathology and may be seen in multiple clinical conditions including metastatic cancer as described in this case.
April 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28321331/ct-patterns-of-organizing-pneumonia-in-patients-treated-with-vegf-mtor-inhibitors-for-metastatic-renal-cell-cancer-an-observational-study
#14
Sabine Dettmer, Viktor Grünwald, Thomas Fuehner, Arnold Ganser, Frank Wacker, Philipp Ivanyi, Thomas Rodt
BACKGROUND: Targeted therapies are the standard treatment in patients with metastatic renal cell carcinoma (mRCC) and are known to cause adverse pulmonary events. Organizing pneumonia (OP) with its various manifestations in computed tomography (CT) has therefore lately received more attention. PURPOSE: To describe the spectrum of CT patterns of OP in patients with mRCC receiving targeted therapies. MATERIAL AND METHODS: Seventeen patients with known therapy-related OP were analyzed retrospectively by two blinded radiologists in consensus...
February 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28270188/pulmonary-alveolar-proteinosis-and-first-successful-whole-lung-lavage-in-sri-lanka-a-case-report
#15
Janith Galhenage, Buddhika Weerasinghe, Wadasinghe Dilesha, Roshana Constantine, Bandu Gunasena
BACKGROUND: Pulmonary alveolar proteinosis is a rare disease characterized by accumulation of lipoproteinaceous material within alveoli. There are three clinically distinct forms: congenital, acquired and secondary. Whole lung lavage is currently the gold standard therapy for severe cases of pulmonary alveolar proteinosis. In Sri Lanka this is the first reported successful whole lung lavage for a patient with pulmonary alveolar proteinosis. CASE PRESENTATION: We describe the case of a 15-year-old Sri Lankan girl who presented with symptoms of progressive shortness of breath and dry cough for 6 months' duration...
March 8, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28090053/a-suspected-case-of-an-alveolar-haemorrhage-caused-by-dasatinib
#16
Yoritake Sakoda, Yojiro Arimori, Masakatsu Ueno, Takafumi Matsumoto
A 39-year-old man treated with dasatinib for chronic myelogenous leukaemia presented to our hospital with haemoptysis, coughing, and dyspnoea. Chest radiography and computed tomography revealed ground-glass opacities and a crazy-paving pattern. Bronchoalveolar lavage was not performed due to serious hypoxemia and bleeding. Significant bleeding from the peripheral bronchi led to a diagnosis of an alveolar haemorrhage. Dasatinib-induced alveolar haemorrhaging was suspected based on the clinical findings. His condition improved immediately after dasatinib withdrawal and initiation of steroid therapy...
2017: Internal Medicine
https://www.readbyqxmd.com/read/27851571/1937-the-crazy-pavings-that-can-drive-you-crazy
#17
Hammad Arshad, Meilin Young, Tariq Cheema
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27814844/pulmonary-alveolar-proteinosis-crazy-paving-to-whole-lung-lavage
#18
Shahnaz Ul Rehman, Jeffrey R Hammersley
No abstract text is available yet for this article.
November 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27766199/a-case-of-lipoid-pneumonia-caused-by-inhalation-of-vaporized-paraffin-from-burning-candles
#19
Hidenori Katsumi, Masaki Tominaga, Morihiro Tajiri, Shigeki Shimizu, Yuki Sakazaki, Takashi Kinoshita, Masaki Okamoto, Tomotaka Kawayama, Tomoaki Hoshino
A 66-year-old woman was referred to our hospital for investigation of interstitial lung disease. She had spent most of her time in a shrine, and had always been exposed to vaporized paraffin from burning candles. Chest High-resolution computed tomography (HRCT)showed ground-glass attenuation with thickening of septal lines, wh create the so-called "crazy-paving appearance". Although bronchoalveolar lavage(BAL) and transbronchial biopsy were performed to aid in diagnosis, the findings did not reveal any conclusive information...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27548000/pulmonary-fibrosis-on-high-resolution-ct-of-patients-with-pulmonary-alveolar-proteinosis
#20
MULTICENTER STUDY
Masanori Akira, Yoshikazu Inoue, Toru Arai, Chikatoshi Sugimoto, Sayoko Tokura, Koh Nakata, Masanori Kitaichi
OBJECTIVE: The CT findings of pulmonary fibrosis in patients with pulmonary alveolar proteinosis (PAP) are not yet well defined. The objective of this study was to evaluate the CT findings of PAP with a focus on pulmonary fibrosis secondary to PAP. MATERIALS AND METHODS: High-resolution CT (HRCT) scans of 44 patients with PAP were evaluated retrospectively with a focus on pulmonary fibrosis: 33 patients had autoimmune PAP, and 11 patients had secondary PAP. The intervals between the initial and last CT examinations ranged from 1 to 284 months (median, 60 months)...
September 2016: AJR. American Journal of Roentgenology
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