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Toxocara canis in childrens

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https://www.readbyqxmd.com/read/27893948/seroprevalence-and-risk-factors-for-toxocara-canis-infection-in-serbia-during-2015
#1
Simona Gabrielli, Suzana Tasić-Otašević, Aleksandra Ignjatović, Maurizio Fraulo, Marija Trenkić-Božinović, Stefan Momčilović, Gabriella Cancrini
We report data on the Toxocara seroprevalence evidenced in 2015 from samples of 40 children and 298 adults of the population living in different areas of Serbia, and on possible association of certain variables with infection. Detection of specific antibodies was performed using an enzyme-linked immunosorbent assay; all ambiguous results and part of the positive and negative sera were further analyzed by confirmatory Western blot test. An overall 23.5% seroprevalence was noticed, which was confirmed in 13.0% of the examined population with no significant difference regarding the age (children = 10...
November 28, 2016: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/27857820/detection-of-specific-antibody-reactivity-to-toxocara-larval-excretory-secretory-antigens-in-asthmatic-patients-5-15-years
#2
Mahdi Mosayebi, Latif Moini, Reza Hajihossein, Mojtaba Didehdar, Zahra Eslamirad
BACKGROUND & PURPOSE: Humans act as an intermediate host for Toxocara canis and Toxocara cati. Toxocara may be an important risk factor for asthma in humans. The aim of the present study was to evaluate immunoglobulin G (IgG) anti-Toxocara canis antibody, using enzyme-linked immunosorbent assay (ELISA) in asthmatic patients (aged 5-15 years), referring to a clinic of pulmonary diseases in Arak, Iran. MATERIALS & METHODS: In this bi-group cross sectional study, serum samples were collected from 110 children with confirmed asthma and 70 children without asthma within one year...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27760094/-ocular-toxocariasis-in-a-boy-with-idiopathic-nephrotic-syndrome-a-case-report
#3
Agnieszka Antonowicz, Piotr Skrzypczyk, Beata Kępa, Małgorzata Pańczyk-Tomaszewska
: Toxocariasis is a common zoonosis caused by infection with Toxocara canis or cati larvae. Ocular toxocariasis is one of the forms of infestation found in 1/1,000 - 1/10,000 children. Children with idiopathic nephrotic syndrome (INS) are at high risk of infections, also parasitic infestations, which can, in turn, cause relapses of the disease. A CASE REPORT: We present a case of a 6-year-old boy with steroiddependent nephrotic syndrome. The disease started at age of 2, the boy had 9 relapses of INS, and was treated with oral prednisone, levamisole, and cyclophosphamide...
October 19, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27723790/serological-evidence-of-exposure-to-globally-relevant-zoonotic-parasites-in-the-estonian-population
#4
Brian Lassen, Marilin Janson, Arvo Viltrop, Kädi Neare, Pirje Hütt, Irina Golovljova, Lea Tummeleht, Pikka Jokelainen
We investigated Estonian population and its selected subgroups for serological evidence of exposure to Ascaris lumbricoides, Echinococcus spp., Taenia solium, Toxocara canis, Toxoplasma gondii, and Trichinella spiralis. Serum samples from 999 adults representing general population, 248 children aged 14-18, 158 veterinarians, 375 animal caretakers, and 144 hunters were tested for specific immunoglobulin G antibodies against the selected parasites using commercial enzyme immunoassays (ELISA). Sera yielding positive or twice grey zone Echinococcus spp, T...
2016: PloS One
https://www.readbyqxmd.com/read/27104477/toxocariasis-and-childhood-asthma-a-case-control-study
#5
Priscila Silva Cadore, Linjie Zhang, Liliam de Lima Lemos, Carolina Lorenzi, Paula de Lima Telmo, Paula Costa Dos Santos, Gabriela Torres Mattos, Flávia Saraçol Vignol, Silvio O M Prietsch, Maria Elisabeth Aires Berne, Carlos James Scaini
OBJECTIVE: The objective of this study is to investigate the association between anti-Toxocara IgG seropositivity and asthma in children. METHODS: This was a case-control study conducted in a university hospital in south Brazil between May 2012 and June 2013. Were recruited 208 children up to 12 years old of whom 156 had asthma (cases) and 52 did not have asthma (controls), with a case-control ratio of 3:1 matched by age. Children's parents or guardians were interviewed using a structured questionnaire with closed questions...
August 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27080332/risk-factors-for-toxocara-spp-seroprevalence-and-its-association-with-atopy-and-asthma-phenotypes-in-school-age-children-in-a-small-town-and-semi-rural-areas-of-northeast-brazil
#6
Márcia B Silva, Ana L M Amor, Leonardo N Santos, Alana A Galvão, Aida V Oviedo Vera, Eduardo S Silva, Cynara Gomes Barbosa, Marilda S Gonçalves, Philip J Cooper, Camila A Figueiredo, Rita de Cassia Ribeiro, Neuza Maria Alcântara-Neves
Toxocara canis, Toxocara cati, are roundworms that live in the intestines of dogs and cats, respectively, and are predominantly agents of human toxocariasis. Studies have suggested that Toxocara spp. seroprevalence increases levels of total and aeroallergen-specific IgE (sIgE), asthma prevalence and asthma morbidity. Nevertheless, other work reported a negative association between Toxocara spp. seropositivity with skin hypersensititity and a positive association with sIgE. The objective of the present study was to evaluate risk factors for acquiring Toxocara spp...
April 11, 2016: Acta Tropica
https://www.readbyqxmd.com/read/26887285/toxocara-canis-anthelmintic-activity-of-quinone-derivatives-in-murine-toxocarosis
#7
T Mata-Santos, H A Mata-Santos, P F Carneiro, K C G De Moura, J M Fenalti, G B Klafke, L A X Cruz, L H R Martins, N F Pinto, M C F R Pinto, M E A Berne, P E A Da Silva, C J Scaini
Human toxocarosis is a chronic tissue parasitosis most often caused by Toxocara canis. The seroprevalence can reach up to 50%, especially among children and adolescents. The anthelmintics used in the treatment have moderate efficacy. The aim of this study was to evaluate the in vitro and in vivo anthelmintic activity of quinones and their derivatives against T. canis larvae and the cytotoxicity of the larvicidal compounds. The compounds were evaluated at 1 mg mL(-1) concentration in microculture plates containing third stage larvae in an Roswell Park Memorial Institute (RPMI) 1640 environment, incubated at 37 °C in 5% CO2 tension for 48 h...
April 2016: Parasitology
https://www.readbyqxmd.com/read/26811731/seroepidemiology-of-toxocariasis-in-children-5-15-yr-old-referred-to-the-pediatric-clinic-of-imam-hossein-hospital-isfahan-iran
#8
Ahmad Hosseini-Safa, Seyed Mohammad Mousavi, Mehran Bahadoran Bagh Badorani, Mehdi Ghatreh Samani, Shayan Mostafaei, Hossein Yousofi Darani
BACKGROUND: Human toxocariasis, a helminthozoonosis, is due to the migration of Toxocara species larvae into human organisms. Humans, especially children become infected by ingesting of embryonated eggs from soil, dirty hands, and raw vegetables. Seroprevalence of this infection is high in developed countries, especially in rural areas. The aim of this study was to investigate the seroepidemiology of Toxocariasis in children referred to the pediatric clinic of Imam Hossein hospital, Isfahan, Iran...
October 2015: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/26752269/molecular-identification-of-ancylostoma-species-from-dogs-and-an-assessment-of-zoonotic-risk-in-low-income-households-s%C3%A3-o-paulo-state-brazil
#9
A P Oliveira-Arbex, E B David, T C G Oliveira-Sequeira, S Katagiri, S T Coradi, S Guimarães
Hookworm infection stands out for its worldwide distribution and for its veterinary and public health relevance. Based on copromicroscopic examinations and polymerase chain reaction (PCR) amplification of the ITS1-5.8S-ITS2 region, we assessed, respectively, the prevalence of intestinal parasites and the identification of canine hookworm species in faeces recovered from 278 dogs living in households of an inland municipality of São Paulo State, Brazil. Intestinal parasites were found in 67.3% of dogs and hookworm infection was found at the highest prevalence rate (56...
January 11, 2016: Journal of Helminthology
https://www.readbyqxmd.com/read/26513899/pediatric-ocular-toxocariasis-in-jiangsu-province-eastern-china
#10
Hai-Fang Zhang, Hai-Yong Hua, Wei Wang
Ocular toxocariasis is caused by migration of a Toxocara larva through the posterior eye. We report the first case of pediatric ocular toxocariasis caused by T. canis in Jiangsu Province, eastern China. A 6-year-old girl presented to Suzhou Municipal Children's Hospital with a complaint of right eye redness, minimal white discharge, no photophobia, eye pain, visual impairment, fever or arthralgia. She was initially diagnosed as having conjunctivitis; however, a 2-month treatment with lomefloxacin 0.3% eye drops gave no improvements...
January 2015: Southeast Asian Journal of Tropical Medicine and Public Health
https://www.readbyqxmd.com/read/26505549/immunodiagnostic-approaches-for-the-detection-of-human-toxocarosis
#11
Vojtech Boldiš, František Ondriska, Eva Špitalská, Katarína Reiterová
Human toxocarosis is an important zoonosis caused by larvae of Toxocara canis/cati. The objective was to evaluate the role of IgG anti-Toxocara antibody detection and the specific IgG avidity in diagnostics of human toxocarosis. Anti-Toxocara IgG antibodies and IgG avidity were evaluated by excretory-secretory (ES)-enzyme-linked immunosorbent assay (ELISA). The IgG anti-Toxocara seroprevalence in people (n = 7678) from western Slovakia was 15.3% and found to be highest in the oldest age groups. The presence of low- IgG avidity in 179 suspected patients for toxocarosis was evaluated in relation to sex, age, IgG antibody levels, eosinophilia, increased total IgE, domicile, geophagia, dog/cat ownership, anamnesis...
December 2015: Experimental Parasitology
https://www.readbyqxmd.com/read/26374832/association-between-toxocariasis-and-cognitive-function-in-young-to-middle-aged-adults
#12
Lance D Erickson, Shawn D Gale, Andrew Berrett, Bruce L Brown, Dawson W Hedges
The ascarid nematodes Toxocara canis (Werner, 1782) and Toxocara cati (Schrank, 1788) may infect humans resulting in toxocariasis. A prior study associated species of Toxocara Stiles, 1905 with cognitive deficits in children. To determine if a similar association between toxocariasis and cognition exists in adults, we analysed a large dataset from the United States' Center for Disease Control's National Health and Nutrition Examination Survey. We used linear-regression and multivariate models to examine the association between toxocariasis as assessed by the presence of anti-Toxocara IgG antibodies and three measures of cognitive function - simple reaction time (SRT), symbol-digit substitution (SDS) and serial-digit learning (SDL) in 4 279 adults aged 21 to 59 years...
2015: Folia Parasitologica
https://www.readbyqxmd.com/read/26339090/sero-epidemiology-of-toxocara-canis-infection-in-children-attending-four-selected-health-facilities-in-the-central-region-of-ghana
#13
MULTICENTER STUDY
G Kyei, I Ayi, J N Boampong, P K Turkson
OBJECTIVE: The study determined the seroprevalence of Toxocara canis infection among children attending four selected health facilities in the Central Region of Ghana. DESIGN: Cross-sectional study. METHOD: Sera from 566 children aged 1-15 years attending four selected health facilities in the Central Region of Ghana between July and September 2012 was used in a Toxocara excretory-secretory antigen-based ELISA to detect serum IgG. A short questionnaire was designed to obtain data on respondents as to age, gender, educational level, locality of residence, habits of washing of fruits, vegetable and hands before eating, keeping of pet (dogs or cats), and history of playing with soil and pets...
June 2015: Ghana Medical Journal
https://www.readbyqxmd.com/read/26246828/soil-contamination-with-toxocara-spp-eggs-in-public-parks-of-mashhad-and-khaf-north-east-of-iran
#14
Fariba Berenji, Abdul Ghayoum Movahedi Rudy, Abdolmajid Fata, Mousa Tavassoli, Mojtaba Mousavi Bazaz, Ghodratolah Salehi Sangani
BACKGROUND: Toxocariasis is an important disease caused by the larvae of parasitic worms such as Toxocara canis and T. cati. Public parks can be the source of toxocariasis for small children. This survey was conducted to determine the prevalence of Toxocara spp. ova in parks of Mashhad and Khaf northeastern Iran. METHODS: In this descriptive cross-sectional study, performed in November 2011 to June 2012, overall, 340 soil samples were collected from 39 parks of Mashhad and 29 parks in Khaf city...
April 2015: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/26217045/seroprevalence-and-risk-factors-of-toxocariasis-in-preschool-children-in-aragua-state-venezuela
#15
María Martínez, Héctor García, Liliana Figuera, Verónica González, Félix Lamas, Katherinne López, Víctor Mijares, Yeasiry Corrales, María Lares, Elizabeth Ferrer
BACKGROUND: Toxocariasis is a widespread zoonotic disease caused by the nematode Toxocara canis. In Venezuela, the magnitude of the disease is unknown and seroepidemiological studies have not been previously carried out in Aragua state. METHODS: A cross-sectional field study was conducted in eight preschools in three municipalities from Aragua state in Venezuela. A total of 224 children aged between 1 and 6 years were studied (43.8% [98/224] male and 56.2% [126/224] female)...
September 2015: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/26204025/risk-of-human-toxocarosis-in-poland-due-to-toxocara-infection-of-dogs-and-cats
#16
Jakub Gawor, Anna Borecka, Magdalena Marczyńska, Sabina Dobosz, Hanna Żarnowska-Prymek
The purpose of this paper was to present the current data on the risk of toxocarosis in humans in Poland and to give an overview of the clinical and diagnostic aspects of the disease. The number of reported clinical cases of Toxocara infection in children in Poland in medical literature has increased recently. The results of field surveys aimed to evaluate the soil contamination with geohelminth eggs conducted during the last few years showed that Toxocara is the most common zoonotic agent in urban public sites and in rural settlements...
March 2014: Acta Parasitologica
https://www.readbyqxmd.com/read/26024905/presence-of-anti-toxocara-canis-antibodies-and-risk-factors-in-children-from-the-amecameca-and-chalco-regions-of-m%C3%A3-xico
#17
Nadyeli Nava Cortés, Camilo Romero Núñez, Bautista Gómez Linda Guiliana, Pedro Abel Hernández García, Rafael Heredia Cárdenas
BACKGROUND: Toxocariasis is a zoonotic disease that poses a threat to public health worldwide. This disease primarily affects children and is caused by the presence in the digestive tract of a common roundworm of dogs, Toxocara canis, or cats, Toxocara cati. Toxocara is responsible for the presentation of various syndromes in humans depending on the affected organs. METHODS: In this study, the prevalence of anti-T. canis antibodies was investigated in children aged 3-16 years from semirural populations in the municipalities of Amecameca and Chalco in México...
2015: BMC Pediatrics
https://www.readbyqxmd.com/read/25960921/intestinal-parasites-of-children-and-adults-in-a-remote-aboriginal-community-of-the-northern-territory-australia-1994-1996
#18
Jennifer Shield, Kieran Aland, Thérèse Kearns, Glenda Gongdjalk, Deborah Holt, Bart Currie, Paul Prociv
INTRODUCTION: Parasitic infections can adversely impact health, nutritional status and educational attainment. This study investigated hookworm and other intestinal parasites in an Aboriginal community in Australia from 1994 to 1996. METHODS: Seven surveys for intestinal parasites were conducted by a quantitative formol-ether method on faecal samples. Serological testing was conducted for Strongyloides stercoralis and Toxocara canis IgG by enzyme-linked immunosorbent assays...
January 2015: Western Pacific Surveillance and Response Journal: WPSAR
https://www.readbyqxmd.com/read/25812836/seroprevalence-disease-awareness-and-risk-factors-for-toxocara-canis-infection-among-primary-schoolchildren-in-makoko-an-urban-slum-community-in-nigeria
#19
Pam V Gyang, Olaoluwa P Akinwale, Yueh-Lun Lee, Ting-Wu Chuang, Akwaowo B Orok, Olusola Ajibaye, Chien-Wei Liao, Po-Ching Chen, Chia-Mei Chou, Ying-Chieh Huang, Ursula Barghouth, Chia-Kwung Fan
In this study, we investigated the seroprevalence of Toxocara canis infection in southern Nigeria, which previously was unknown, in addition to evaluating disease awareness and potential risk factors for schoolchildren in an urban slum community. In total, 366 primary schoolchildren were investigated for the presence of anti-Toxocara IgG antibodies. Blood was collected and screened by a Western blot analysis based on the excretory-secretory antigens of larval T. canis (TcES), targeting low molecular weight bands of 24-35kDa specific for T...
June 2015: Acta Tropica
https://www.readbyqxmd.com/read/25748709/immunopathological-changes-in-the-brain-of-immunosuppressed-mice-experimentally-infected-with-toxocara-canis
#20
Mohamed M Eid, Samy I El-Kowrany, Ahmad A Othman, Dina I El Gendy, Eman M Saied
Toxocariasis is a soil-transmitted helminthozoonosis due to infection of humans by larvae of Toxocara canis. The disease could produce cognitive and behavioral disturbances especially in children. Meanwhile, in our modern era, the incidence of immunosuppression has been progressively increasing due to increased incidence of malignancy as well as increased use of immunosuppressive agents. The present study aimed at comparing some of the pathological and immunological alterations in the brain of normal and immunosuppressed mice experimentally infected with T...
February 2015: Korean Journal of Parasitology
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