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https://www.readbyqxmd.com/read/29330014/frequency-of-red-blood-cell-genotypes-in-multi-transfused-patients-and-blood-donors-from-minas-gerais-southeast-brazil
#1
Vitor Mendonça Alves, Fernanda Bernadelli De Vito, Paulo Roberto Juliano Martins, Sheila Soares Silva, Lilian Castilho, Helio Moraes-Souza
BACKGROUND AND OBJECTIVES: The frequency of red blood cell (RBC) antigens in Brazil varies due to differences in the ethnic groups in different regions; however, these studies have not been performed in Minas Gerais, where African admixture is more prevalent in comparison with other states. Due to these facts, this study aimed to determine the frequency of RBC genotypes on Rh, Kell, Duffy and Kidd systems in blood donors and multi-transfused patients from Minas Gerais, Southeast Brazil...
December 16, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29326454/primary-dental-care-rubber-dam-feather-fingers-and-reflection
#2
E Kidd
No abstract text is available yet for this article.
January 12, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29323481/new-mechanism-of-extractive-electrospray-ionization-mass-spectrometry-for-heterogeneous-solid-particles
#3
S Kumbhani, T Longin, L M Wingen, C Kidd, V Perraud, B J Finlayson-Pitts
Real-time in situ mass spectrometry analysis of airborne particles is important in several applications, including exposure studies in ambient air, industrial settings, and assessing impacts on visibility and climate. However, obtaining molecular and 3D structural information is more challenging, especially for heterogeneous solid or semisolid particles. We report a study of extractive electrospray ionization mass spectrometry (EESI-MS) for the analysis of solid particles with an organic coating. The goal is to elucidate how much of the overall particle content is sampled, and determine the sensitivity of this technique to the surface layers...
January 11, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29320883/the-prevalence-of-oral-stage-dysphagia-in-adults-presenting-with-temporomandibular-disorders-a-systematic-review-and-meta-analysis
#4
Órla Gilheaney, Sibylle Béchet, Patrick Kerr, Ciaran Kenny, Shauna Smith, Rita Kouider, Rachel Kidd, Margaret Walshe
OBJECTIVE: Temporomandibular disorders (TMDs) are the most commonly experienced non-dental orofacial pain disorders, with pain and dysfunction potentially resulting in oral stage dysphagia (OD). However, limited research has been conducted on this condition, with potential negative effects on clinical practice. Therefore, the aim of this study was to determine the prevalence of OD in adults presenting with TMDs, diagnosed as per the Research Diagnostic Criteria for Temporomandibular Disorders or the Diagnostic Criteria for Temporomandibular Disorders protocols...
January 11, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29301420/the-american-psychiatric-association-practice-guideline-for-the-pharmacological-treatment-of-patients-with-alcohol-use-disorder
#5
Victor I Reus, Laura J Fochtmann, Oscar Bukstein, A Evan Eyler, Donald M Hilty, Marcela Horvitz-Lennon, Jane Mahoney, Jagoda Pasic, Michael Weaver, Cheryl D Wills, Jack McIntyre, Jeremy Kidd, Joel Yager, Seung-Hee Hong
No abstract text is available yet for this article.
January 1, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29290374/physical-compatibility-of-meropenem-and-vaborbactam-with-select-intravenous-drugs-during-simulated-y-site-administration
#6
James M Kidd, Lindsay M Avery, Tomefa E Asempa, David P Nicolau, Joseph L Kuti
PURPOSE: Meropenem/vaborbactam is a novel intravenous antibiotic combining the carbapenem, meropenem, with a novel β-lactamase inhibitor, vaborbactam. Meropenem/vaborbactam is administered as a 3-hour infusion given every 8 hours, thereby potentially restricting an intravenous line for 9 h/d. Intravenous medications may be given concurrently via Y-site when compatibility data are available. Herein, physical compatibility was determined for the identification which medications can be coadministered with meropenem/vaborbactam via Y-site...
December 28, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29277256/individual-differences-in-language-acquisition-and-processing
#7
REVIEW
Evan Kidd, Seamus Donnelly, Morten H Christiansen
Humans differ in innumerable ways, with considerable variation observable at every level of description, from the molecular to the social. Traditionally, linguistic and psycholinguistic theory has downplayed the possibility of meaningful differences in language across individuals. However, it is becoming increasingly evident that there is significant variation among speakers at any age as well as across the lifespan. Here, we review recent research in psycholinguistics, and argue that a focus on individual differences (IDs) provides a crucial source of evidence that bears strongly upon core issues in theories of the acquisition and processing of language; specifically, the role of experience in language acquisition, processing, and attainment, and the architecture of the language system...
December 22, 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/29274095/alterations-in-ca1-hippocampal-synapses-in-a-mouse-model-of-fragile-x-syndrome
#8
Safdar Jawaid, Grahame J Kidd, Jing Wang, Carrie Swetlik, Ranjan Dutta, Bruce D Trapp
Fragile X Syndrome (FXS) is the major cause of inherited mental retardation and the leading genetic cause of Autism spectrum disorders. FXS is caused by mutations in the Fragile X Mental Retardation 1 (Fmr1) gene, which results in transcriptional silencing of Fragile X Mental Retardation Protein (FMRP). To elucidate cellular mechanisms involved in the pathogenesis of FXS, we compared dendritic spines in the hippocampal CA1 region of adult wild-type (WT) and Fmr1 knockout (Fmr1-KO) mice. Using diolistic labeling, confocal microscopy, and three-dimensional electron microscopy, we show a significant increase in the diameter of secondary dendrites, an increase in dendritic spine density, and a decrease in mature dendritic spines in adult Fmr1-KO mice...
December 23, 2017: Glia
https://www.readbyqxmd.com/read/29273541/effect-of-bacterial-inoculants-on-phytomining-of-metals-from-waste-incineration-bottom-ash
#9
Theresa Rosenkranz, Petra Kidd, Markus Puschenreiter
Waste incineration bottom ash is considered a secondary resource for valuable trace elements (TE), which is currently neglected in most European countries. Phytomining could potentially recover valuable TE from such waste materials but is still at an exploratory stage with many challenges. The use of bioaugmentation to improve plant growth and TE accumulation of metal-tolerant high biomass plants growing on waste incineration bottom ash was evaluated. Bacterial strains that were previously isolated from rhizosphere, roots and contaminated soil were selected according to their plant growth promoting characteristics and tolerance to the bottom ash substrate...
December 19, 2017: Waste Management
https://www.readbyqxmd.com/read/29259276/long-term-carbon-sink-in-borneo-s-forests-halted-by-drought-and-vulnerable-to-edge-effects
#10
Lan Qie, Simon L Lewis, Martin J P Sullivan, Gabriela Lopez-Gonzalez, Georgia C Pickavance, Terry Sunderland, Peter Ashton, Wannes Hubau, Kamariah Abu Salim, Shin-Ichiro Aiba, Lindsay F Banin, Nicholas Berry, Francis Q Brearley, David F R P Burslem, Martin Dančák, Stuart J Davies, Gabriella Fredriksson, Keith C Hamer, Radim Hédl, Lip Khoon Kho, Kanehiro Kitayama, Haruni Krisnawati, Stanislav Lhota, Yadvinder Malhi, Colin Maycock, Faizah Metali, Edi Mirmanto, Laszlo Nagy, Reuben Nilus, Robert Ong, Colin A Pendry, Axel Dalberg Poulsen, Richard B Primack, Ervan Rutishauser, Ismayadi Samsoedin, Bernaulus Saragih, Plinio Sist, J W Ferry Slik, Rahayu Sukmaria Sukri, Martin Svátek, Sylvester Tan, Aiyen Tjoa, Mark van Nieuwstadt, Ronald R E Vernimmen, Ishak Yassir, Petra Susan Kidd, Muhammad Fitriadi, Nur Khalish Hafizhah Ideris, Rafizah Mat Serudin, Layla Syaznie Abdullah Lim, Muhammad Shahruney Saparudin, Oliver L Phillips
Less than half of anthropogenic carbon dioxide emissions remain in the atmosphere. While carbon balance models imply large carbon uptake in tropical forests, direct on-the-ground observations are still lacking in Southeast Asia. Here, using long-term plot monitoring records of up to half a century, we find that intact forests in Borneo gained 0.43 Mg C ha-1 per year (95% CI 0.14-0.72, mean period 1988-2010) above-ground live biomass. These results closely match those from African and Amazonian plot networks, suggesting that the world's remaining intact tropical forests are now en masse out-of-equilibrium...
December 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/29248957/ancestry-inference-of-96-population-samples-using-microhaplotypes
#11
Ozlem Bulbul, Andrew J Pakstis, Usha Soundararajan, Cemal Gurkan, Jane E Brissenden, Janet M Roscoe, Baigalmaa Evsanaa, Ariunaa Togtokh, Peristera Paschou, Elena L Grigorenko, David Gurwitz, Sharon Wootton, Robert Lagace, Joseph Chang, William C Speed, Kenneth K Kidd
Microhaplotypes have become a new type of forensic marker with a great ability to identify and deconvolute mixtures because massively parallel sequencing (MPS) allows the alleles (haplotypes) of the multi-SNP loci to be determined directly for an individual. As originally defined, a microhaplotype locus is a short segment of DNA with two or more SNPs defining three or more haplotypes. The length is short enough, less than about 300 bp, that the read length of current MPS technology can produce a phase-known sequence of each chromosome of an individual...
December 16, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29240740/characteristics-of-and-differences-between-pasifika-women-and-new-zealand-european-women-diagnosed-with-breast-cancer-in-new-zealand
#12
Charis Brown, Chunhuan Lao, Ross Lawrenson, Sandar Tin Tin, Michelle Schaaf, Jacquie Kidd, Anne Allan-Moetaua, Josephine Herman, Reena Raamsroop, Ian Campbell, Mark Elwood
AIM: Breast cancer in New Zealand-based Pasifika women is a significant issue. Although Pasifika women have a lower incidence of breast cancer compared to New Zealand European women, they have higher breast cancer mortality and lower five-year survival. The aim of this study was to describe the characteristics and tumour biology of Pasifika women and to compare New Zealand European women to identify what factors impact on early (Stage 1 and 2) vs advanced stage (Stage 3 and 4) at diagnosis...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29218867/cell-specific-prediction-and-application-of-drug-induced-gene-expression-profiles
#13
Rachel Hodos, Ping Zhang, Hao-Chih Lee, Qiaonan Duan, Zichen Wang, Neil R Clark, Avi Ma'ayan, Fei Wang, Brian Kidd, Jianying Hu, David Sontag, Joel Dudley
Gene expression profiling of in vitro drug perturbations is useful for many biomedical discovery applications including drug repurposing and elucidation of drug mechanisms. However, limited data availability across cell types has hindered our capacity to leverage or explore the cell-specificity of these perturbations. While recent efforts have generated a large number of drug perturbation profiles across a variety of human cell types, many gaps remain in this combinatorial drug-cell space. Hence, we asked whether it is possible to fill these gaps by predicting cell-specific drug perturbation profiles using available expression data from related conditions--i...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29212948/elevated-urinary-creld2-is-associated-with-endoplasmic-reticulum-stress-mediated-kidney-disease
#14
Yeawon Kim, Sun-Ji Park, Scott R Manson, Carlos Af Molina, Kendrah Kidd, Heather Thiessen-Philbrook, Rebecca J Perry, Helen Liapis, Stanislav Kmoch, Chirag R Parikh, Anthony J Bleyer, Ying Maggie Chen
ER stress has emerged as a signaling platform underlying the pathogenesis of various kidney diseases. Thus, there is an urgent need to develop ER stress biomarkers in the incipient stages of ER stress-mediated kidney disease, when a kidney biopsy is not yet clinically indicated, for early therapeutic intervention. Cysteine-rich with EGF-like domains 2 (CRELD2) is a newly identified protein that is induced and secreted under ER stress. For the first time to our knowledge, we demonstrate that CRELD2 can serve as a sensitive urinary biomarker for detecting ER stress in podocytes or renal tubular cells in murine models of podocyte ER stress-induced nephrotic syndrome and tunicamycin- or ischemia-reperfusion-induced acute kidney injury (AKI), respectively...
December 7, 2017: JCI Insight
https://www.readbyqxmd.com/read/29208399/association-between-extracellular-material-and-biofilm-formation-in-response-to-sodium-hypochlorite-by-clinical-isolates-of-enterococcus-faecalis
#15
Austin Yoo, Giampiero Rossi-Fedele, Stephen P Kidd, Anthony H Rogers, Peter S Zilm
INTRODUCTION: Extracellular material (ECM) surrounding Enterococcus faecalis may play a role in increasing resistance to environmental stresses. Our aim was to determine ECM levels in response to subminimal inhibitory concentrations of sodium hypochlorite (sub-MIC/NaOCl) or anaerobic growth and determine the impact on biofilm development. METHODS: From 37 E. faecalis clinical strains, 19 were selected according to their biofilm-producing ability by using a crystal violet biofilm assay: 10 strong, 4 intermediate, and 5 non-biofilm producers...
December 2, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29203024/rage-against-the-machine-google-s-self-driving-cars-versus-human-drivers
#16
Eric R Teoh, David G Kidd
INTRODUCTION: Automated driving represents both challenges and opportunities in highway safety. Google has been developing self-driving cars and testing them under employee supervision on public roads since 2009. These vehicles have been involved in several crashes, and it is of interest how this testing program compares to human drivers in terms of safety. METHODS: Google car crashes were coded by type and severity based on narratives released by Google. Crash rates per million vehicle miles traveled (VMT) were computed for crashes deemed severe enough to be reportable to police...
December 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/29201454/the-role-of-peptide-receptor-radionuclide-therapy-in-advanced-metastatic-thoracic-neuroendocrine-tumors
#17
REVIEW
Lisa Bodei, Jarosław B Ćwikla, Mark Kidd, Irvin M Modlin
Bronchopulmonary (BP) neuroendocrine tumors (NETs) comprise a spectrum of tumors that develop from respiratory neuroendocrine cells and represent ~20% of all lung neoplasia and ~30% of all NETs. The only curative treatment is surgical resection. For well-differentiated forms (typical and atypical carcinoids), medical therapy ranges from bioactive agents (e.g., somatostatin analogs), to biotherapy (e.g., everolimus), standard chemotherapy and peptide receptor radionuclide therapy (PRRT). PRRT with radiolabeled somatostatin analogs is an innovative treatment for inoperable or metastasized, well/moderately differentiated, NET...
November 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29201449/molecular-strategies-in-the-management-of-bronchopulmonary-and-thymic-neuroendocrine-neoplasms
#18
REVIEW
Irvin M Modlin, Mark Kidd, Pier-Luigi Filosso, Matteo Roffinella, Anna Lewczuk, Jaroslaw Cwikla, Lisa Bodei, Agnieska Kolasinska-Cwikla, Kyung-Min Chung, Margot E Tesselaar, Ignat A Drozdov
Thoracic NETs [bronchopulmonary NETs (BPNETs) and thymic NETs (TNET)] share a common anatomic primary location, likely a common cell of origin, the "Kulchitsky cell" and presumably, a common etiopathogenesis. Although they are similarly grouped into well-differentiated [typical carcinoids (TC) and atypical carcinoids (AC)] and poorly differentiated neoplasms and both express somatostatin receptors, they exhibit a wide variation in clinical behavior. TNETs are more aggressive, are frequently metastatic, and have a lower 5-year survival rate (~50% vs...
November 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29198879/radiation-therapy-improves-disease-specific-survival-in-women-with-stage-ii-endometrioid-endometrial-cancer-brachytherapy-may-be-sufficient
#19
Chika R Nwachukwu, Rie Von-Eyben, Elizabeth A Kidd
PURPOSE: To evaluate disease-specific survival (DSS) outcomes in Stage II endometrioid endometrial cancer (EC) patients based on pathology and treatment information including adjuvant radiotherapy and lymph node assessment. METHODS AND MATERIALS: Using the Surveillance, Epidemiology, and End Results database, 2877 patients with Stage II EC diagnosed between 2004 and 2012 treated with radiation were identified. DSS was determined for different modalities of radiation...
November 30, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29194005/patient-characteristics-length-of-stay-and-functional-improvement-for-schizophrenia-spectrum-disorders-a-population-study-of-inpatient-care-in-ontario-2005-to-2015
#20
Sheng Chen, April Collins, Kelly Anderson, Kwame McKenzie, Sean Kidd
OBJECTIVES: Schizophrenia and associated illnesses account for a large proportion of mental illness burden and health care expenditures, with the majority of expense involving inpatient care. To date, the literature exploring factors associated with length of stay (LOS) and functional improvement during inpatient care is underdeveloped. In response, this study examined the association between patient characteristics, LOS, and functional improvement using Ontario Mental Health Reporting System (OMHRS) data from 2005 to 2015...
December 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
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