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Respiratory AND newborn

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https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#1
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29662279/there-is-only-a-modest-increase-in-neonatal-respiratory-morbidity-following-early-term-elective-cesarean-in-a-south-indian-population
#2
Nagaraja Katwa, Akhila Vasudeva, Leslie E S Lewis, Pratap Kumar
Objectives: Elective cesarean deliveries (ECD) are still performed prior to 39 weeks. This study aimed to identify risk of neonatal respiratory morbidity (NRM) following ECD near term, in a South Indian population. Specifically, study aimed to measure the additional healthcare burden due to large number of ECDs performed prior to 39 weeks, in this local population. Methods: We analyzed NRM among 1329 deliveries (584 ECD and 745 spontaneous vaginal delivery, SVD) in a tertiary hospital over 2 years...
April 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29652876/rehabilitation-of-sucking-and-swallowing-alterations-in-premature-newborn-at-the-neonatal-intensive-care-unit
#3
Edda Aguilar-Vázquez, M Lucía Pérez-Padilla, M de Lourdes Martín-López, Adriana Abigail Romero-Hernández
Over the last 20 years, 640 premature newborns with alterations in suction-deglution have been taken care of in the neonatal intensive care unit at the Hospital Infantil de México Federico Gómez, using techniques for patients with immaturity, and neurological, gastrointestinal, cardiologic and respiratory pathologies. This descriptive study includes the treatment employed mainly in premature newborns during this period. Suction, swallowing and breathing coordination are some of the most complex abilities that premature newborns face, due to their anatomofunctional immaturity and improper sensoriomotor integration for the high energy requirements they must meet...
2018: Boletín Médico del Hospital Infantil de México
https://www.readbyqxmd.com/read/29649792/comparison-of-different-compression-to-ventilation-ratios-2-1-3-1-and-4-1-during-cardiopulmonary-resuscitation-in-a-porcine-model-of-neonatal-asphyxia
#4
Matteo P Pasquin, Po-Yin Cheung, Sparsh Patel, Min Lu, Tze-Fun Lee, Michael Wagner, Megan O'Reilly, Georg M Schmölzer
BACKGROUND: High-quality chest compression is essential during neonatal cardiopulmonary resuscitation (CPR). However, the optimal compression to ventilation ratio (C:V) that should be used during neonatal CPR to optimize coronary and cerebral perfusion while providing adequate ventilation remains unknown. OBJECTIVE: We hypothesized that different C:V ratios (e.g., 2: 1 or 4: 1) will reduce the time to return of spontaneous circulation (ROSC) in severely asphyxiated piglets...
April 12, 2018: Neonatology
https://www.readbyqxmd.com/read/29627126/vaccination-against-tuberculosis
#5
Carlos Martin, Nacho Aguilo, Jesús Gonzalo-Asensio
BCG (Bacille Calmette-Guérin) vaccination is included in the immunization schedule for tuberculosis endemic countries with a global coverage at birth close to 90% worldwide. BCG was attenuated from Mycobacterium bovis almost a century ago, and provides a strong protection against disseminated forms of the disease, though very limited against pulmonary forms of tuberculosis, responsible for transmission. Novel prophylactic tuberculosis vaccines are in clinical development either to replace BCG or to improve its protection against respiratory forms of the disease...
April 4, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29619212/validity-of-maternal-report-of-care-seeking-for-childhood-illness
#6
Emily D Carter, Micky Ndhlovu, Melinda Munos, Emmy Nkhama, Joanne Katz, Thomas P Eisele
Background: Accurate data on care-seeking for child illness are needed to improve public health programs and reduce child mortality. The accuracy of maternal report of care-seeking for child illness as collected through household surveys has not been validated. Methods: A 2016 survey compared reported care-seeking against a gold-standard of health care provider documented care-seeking events among a random sample of mothers of children <5 years in Southern Province, Zambia...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29615635/characterization-of-sex-based-dna-methylation-signatures-in-the-airways-during-early-life
#7
Cesar L Nino, Geovanny F Perez, Natalia Isaza, Maria J Gutierrez, Jose L Gomez, Gustavo Nino
Human respiratory conditions are largely influenced by the individual's sex resulting in overall higher risk for males. Sex-based respiratory differences are present at birth suggesting a strong genetic component. Our objective was to characterize early life sex-based genomic signatures determined by variable X-chromosome methylation in the airways. We compared male versus female genome-wide DNA methylation in nasal airway samples from newborns and infants aged 1-6 months (N = 12). We analyzed methylation signals across CpG sites mapped to each X-linked gene using an unsupervised classifier (principal components) followed by an internal evaluation and an exhaustive cross-validation...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29615156/promoting-newborn-safety-using-the-rappt-assessment-and-considering-apgar-criteria-a-quality-improvement-project
#8
Susan M Ludington-Hoe, Barbara L Morrison-Wilford, Marguerite DiMarco, Marilyn Lotas
PURPOSE: The aim of this project was to evaluate the implementation of the Respiratory, Activity, Perfusion, Position, and Tone (RAPPT) instrument in assessing the infant's transition to extrauterine life while in skin-to-skin contact (SSC). Sample/Design: Nurses (n = 17) completed a pretest and posttest of RAPPT and Apgar scoring knowledge, attended an in-service about accurate scoring, and were observed during 17 deliveries when newborns were in SSC. OUTCOME VARIABLES: Primary variables were knowledge scores, use of RAPPT, and accurate RAPPT scoring...
March 1, 2018: Neonatal Network: NN
https://www.readbyqxmd.com/read/29613970/transient-tachypnea-of-the-newborn-is-associated-with-an-increased-risk-of-hospitalization-due-to-rsv-bronchiolitis
#9
Santtu Heinonen, Liina Süvari, Mika Gissler, Olli Pitkänen, Sture Andersson, Otto Helve
BACKGROUND: Transient tachypnea of the newborn (TTN) is a self-limiting respiratory disorder, resulting from a failure to clear the lungs of perinatal fluid. As similar pathophysiological features are present in children with respiratory syncytial virus (RSV) bronchiolitis, we hypothesized that these two conditions may be connected. METHODS: This was a population-based cohort study that included all children born in term (≥37 weeks of gestation) without congenital malformations in Finland between 1996 and 2015...
April 2, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29611314/a-ventilated-newborn-with-respiratory-distress-abdominal-distension-and-scrotal-swelling
#10
(no author information available yet)
No abstract text is available yet for this article.
April 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29611312/a-ventilated-newborn-with-respiratory-distress-abdominal-distension-and-scrotal-swelling
#11
Xenophon Sinopidis, Sotirios Fouzas, Gabriel Dimitriou, Ageliki Karatza
No abstract text is available yet for this article.
April 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29607416/correlation-of-retinopathy-of-prematurity-with-bronchopulmonary-dysplasia
#12
Wojciech Podraza, Beata Michalczuk, Karolina Jezierska, Hanna Domek, Agnieszka Kordek, Beata Łoniewska, Monika Modrzejewska, Joanna Kot
Retinopathy of prematurity (ROP) and bronchopulmonary dysplasia (BPD) are diseases that occur only in preterm infants. The etiology of these disorders is multifactorial; however, it is believed that some of the factors in children presenting with BPD affect both the initiation and severity of ROP. The aim of the study was to evaluate the degree of clinical severity of ROP in infants with BPD compared to those without BPD. Methodology: Infants were divided into two groups: the BPD+ study group and BPD- control group...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29604118/what-does-lung-function-tell-us-about-respiratory-multimorbidity-in-childhood-and-early-adulthood-results-from-the-mas-birth-cohort-study
#13
Dirk Schramm, Marvin Reuter, Linus B Grabenhenrich, Antje Schuster, Christiane Lex, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Renate L Bergmann, Karl E Bergmann, Ulrich Wahn, Thomas Keil, Susanne Lau
BACKGROUND: Interaction of respiratory multimorbidity and lung function has not been examined in longitudinal population studies. We aimed to assess the association of multimorbidity of asthma and rhinitis with lung function and bronchial hyperresponsiveness in comparison to single and no allergies from early school age to young adulthood. METHODS: In 1990, the Multicenter Allergy Study birth cohort recruited 1314 newborns from 5 German cities. At 7, 13 and 20 years, we performed lung function and bronchial challenge tests...
March 31, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29599068/acute-responses-to-diuretic-therapy-in-extremely-low-gestational-age-newborns-results-from-the-prematurity-and-respiratory-outcomes-program-cohort-study
#14
Carol J Blaisdell, James Troendle, Anne Zajicek
OBJECTIVE: To determine if daily respiratory status improved more in extremely low gestational age (GA) premature infants after diuretic exposure compared with those not exposed in modern neonatal intensive care units. STUDY DESIGN: The Prematurity and Respiratory Outcomes Program (PROP) was a multicenter observational cohort study of 835 extremely premature infants, GAs of 230/7 -286/7 weeks, enrolled in the first week of life from 13 US tertiary neonatal intensive care units...
March 20, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29598896/effects-of-hammock-positioning-in-behavioral-status-vital-signs-and-pain-in-preterms-a-case-series-study
#15
Valdecira Rodrigues de Jesus, Pricila Mara Novais de Oliveira, Vivian Mara Gonçalves de Oliveira Azevedo
BACKGROUND: The hammock positioning within the incubators simulates the intrauterine environment, however, there is little evidence of its benefits and possible risks. OBJECTIVES: The aim of this study was to assess the effects of hammock positioning on behavioral status, vital signs, and pain in very low birth weight preterm newborns. METHODS: This is a quasi-experimental/case series study in which premature infants (<1500g) were positioned in supine for one hour in a hammock...
March 15, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29593062/novel-selective-medium-for-the-isolation-of-corynebacterium-kroppenstedtii-from-heavily-colonised-clinical-specimens
#16
Sally Cheuk Ying Wong, Rosana W S Poon, Chuen-Hing Foo, Antonio H Y Ngan, Herman Tse, Vivian C M Lam, Tiffany H Y Leung, Chun-Pong Wong, Vincent C C Cheng, Jonathan H K Chen, Kwok-Yung Yuen
AIMS: Granulomatous mastitis due to Corynebacterium kroppenstedtii is an increasingly recognised cause of an indolent and distressing mastitis in non-lactating females. This slow-growing lipophilic organism is not reliably isolated using routine culture methods. A novel selective culture medium (CKSM) is designed to optimise the isolation of this organism from clinical specimens. METHODS: CKSM contains 10% galactose and Tween 80 (10%) to enhance the growth of C...
March 28, 2018: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29582254/2-4-dinitrophenol-attenuates-mitochondrial-dysfunction-and-improves-neurobehavioral-outcomes-postanoxia-in-neonatal-rats
#17
Puneet K Samaiya, Gopeshwar Narayan, Ashok Kumar, Sairam Krishnamurthy
Following anoxia, a rapid and marked mitochondrial-linked cell death occurs in the cerebral cortex of newborn rats which leads to insult advancement within a couple of days and causes lifelong neurobehavioral abnormalities. The present study investigated the role of 2,4 dinitrophenol (2,4 DNP) in three doses, i.e.,1, 2.5, and 5 mg/kg on anoxia-induced time-dependent mitochondrial dysfunction and associated neurobehavioral outcome using a well-established global model of anoxia. Briefly, rat pups of 30-h age (P2) were subjected to two episodes of anoxia (10 min each) at 24 h of the time interval in an enclosed chamber supplied with 100% N2 and immersed in a water bath (35-37 °C) to avoid hypothermia...
March 26, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29580679/accuracy-of-pulse-oximetry-screening-for-critical-congenital-heart-defects-after-home-birth-and-early-postnatal-discharge
#18
Ilona C Narayen, Nico A Blom, Nan van Geloven, Ellen I M Blankman, Annique J M van den Broek, Martijn Bruijn, Sally-Ann B Clur, Frank A van den Dungen, Hester M Havers, Henriëtte van Laerhoven, Shahryar E Mir, Moira A Muller, Odette M Polak, Lukas A J Rammeloo, Gracita Ramnath, Sophie R D van der Schoor, Anton H van Kaam, Arjan B Te Pas
OBJECTIVE: To assess the accuracy of pulse oximetry screening for critical congenital heart defects (CCHDs) in a setting with home births and early discharge after hospital deliveries, by using an adapted protocol fitting the work patterns of community midwives. STUDY DESIGN: Pre- and postductal oxygen saturations (SpO2 ) were measured ≥1 hour after birth and on day 2 or 3. Screenings were positive if the SpO2 measurement was <90% or if 2 independent measures of pre- and postductal SpO2 were <95% and/or the pre-/postductal difference was >3%...
March 23, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29576209/-intervention-and-role-of-the-paediatrician-in-the-delivery-room
#19
Yohan Sorèze
Some newborns require the presence of a paediatrician in the delivery room, for emergency care. This generally leads to hospitalisation in neonatal intensive care or neonatology. Prematurity and respiratory distress are the main causes. These unexpected situations are a source of anxiety for the parents. It is essential that the multidisciplinary team draws on both its technical and relational expertise, in order to provide optimal treatment to the infant while supporting the parents with the necessary empathy...
March 2018: Soins. Pédiatrie, Puériculture
https://www.readbyqxmd.com/read/29572587/neonatal-abstinence-syndrome-nas-in-southwestern-border-states-examining-trends-population-correlates-and-implications-for-policy
#20
Khaleel S Hussaini, Luigi F Garcia Saavedra
Introduction Neonatal abstinence syndrome (NAS) is withdrawal syndrome in newborns following birth and is primarily caused by maternal drug use during pregnancy. This study examines trends, population correlates, and policy implications of NAS in two Southwest border states. Materials and Methods A cross-sectional analysis of Hospital Inpatient Discharge Data (HIDD) was utilized to examine the incidence of NAS in the Southwest border states of Arizona (AZ) and New Mexico (NM). All inpatient hospital births in AZ and NM from January 1, 2008 through December 31, 2013 with ICD9-CM codes for NAS (779...
March 23, 2018: Maternal and Child Health Journal
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