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Respiratory AND preterm

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https://www.readbyqxmd.com/read/29926973/heart-rate-respiratory-rate-apnoeas-and-peripheral-arterial-oxygen-saturation-in-healthy-term-neonates-during-quiet-sleep
#1
B Bohnhorst, K Seidel, C Böhne, C Peter, S Pirr
AIM: This study compiled percentiles for cardiorespiratory parameters in healthy term neonates during quiet sleep. METHODS: We enrolled 215 healthy term neonates born at Hannover Medical School, Germany, between October 2011 and March 2013. They were prospectively observed on the maternity ward at a median age of two days using six-hour recordings of pulse oximeter plethysmography, oxygen saturation, thoracic breathing movements and electrocardiogram during sleep in a supine position...
June 21, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29926474/neonatal-interventions-for-preventing-cerebral-palsy-an-overview-of-cochrane-systematic-reviews
#2
REVIEW
Emily Shepherd, Rehana A Salam, Philippa Middleton, Shanshan Han, Maria Makrides, Sarah McIntyre, Nadia Badawi, Caroline A Crowther
BACKGROUND: Cerebral palsy is an umbrella term that encompasses disorders of movement and posture attributed to non-progressive disturbances occurring in the developing foetal or infant brain. As there are diverse risk factors and aetiologies, no one strategy will prevent cerebral palsy. Therefore, there is a need to systematically consider all potentially relevant interventions for prevention. OBJECTIVES: PrimaryTo summarise the evidence from Cochrane Systematic Reviews regarding effects of neonatal interventions for preventing cerebral palsy (reducing cerebral palsy risk)...
June 20, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29925674/impact-of-improved-cookstoves-on-women-s-and-child-health-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis
#3
Megha Thakur, Paulien A W Nuyts, Esther A Boudewijns, Javier Flores Kim, Timor Faber, Giridhara R Babu, Onno C P van Schayck, Jasper V Been
OBJECTIVES: Improved biomass cookstoves may help reduce the substantial global burden of morbidity and mortality due to household air pollution (HAP) that disproportionately affects women and children in low and middle income countries (LMICs). DESIGN: Systematic review and meta-analysis of (quasi-)experimental studies identified from 13 electronic databases (last update: 6 April 2018), reference and citation searches and via expert consultation. SETTING: LMICs PARTICIPANTS: Women and children INTERVENTIONS: Improved biomass cookstoves MAIN OUTCOME MEASURES: Low birth weight (LBW), preterm birth, perinatal mortality, paediatric acute respiratory infections (ARIs) and COPD among women...
June 20, 2018: Thorax
https://www.readbyqxmd.com/read/29924738/obstetrical-maternal-and-neonatal-outcomes-in-pregnancies-affected-by-muscular-dystrophy
#4
Adriano Petrangelo, Eman Alshehri, Nicholas Czuzoj-Shulman, Haim A Abenhaim
OBJECTIVE: Pregnancies in women affected by a muscular dystrophy are at an increased risk of adverse maternal and neonatal outcomes due to the effect of the disease on the muscular, cardiac and respiratory systems. We sought to evaluate the risk of adverse outcomes within a large population-based cohort study. METHODS: We used the data extracted from the Nationwide Inpatient Sample (NIS) to conduct a retrospective population-based cohort study consisting of over 12 million births that occurred in the United States between 1999 and 2013...
June 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29924737/outcomes-in-oligohydramnios-the-role-of-etiology-in-predicting-pulmonary-morbidity-mortality
#5
Ashley Hesson, Elizabeth Langen
OBJECTIVE: Early-onset oligohydramnios is typically secondary to renal-urinary anomalies (RUA) or preterm premature rupture of membranes (PPROM). We compared neonatal pulmonary outcomes between these etiologies. METHODS: We conducted a retrospective cohort study of women with oligohydramnios identified before 24 completed weeks of gestation attributed to either PPROM or RUA. Patients were excluded if other fetal anomalies were noted. Respiratory morbidity was assessed by the need for oxygen at 36 corrected weeks or at hospital discharge...
June 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29920638/respiratory-syncytial-virus-hospitalizations-among-u-s-preterm-infants-compared-with-term-infants-before-and-after-the-2014-american-academy-of-pediatrics-guidance-on-immunoprophylaxis-2012-2016
#6
Mitchell Goldstein, Leonard R Krilov, Jaime Fergie, Kimmie K McLaurin, Sally W Wade, David Diakun, Gregory M Lenhart, Adam Bloomfield, Amanda M Kong
OBJECTIVE:  The objective of this study was to compare risk for respiratory syncytial virus (RSV) hospitalizations (RSVH) for preterm infants 29 to 34 weeks gestational age (wGA) versus term infants before and after 2014 guidance changes for immunoprophylaxis (IP), using data from the 2012 to 2016 RSV seasons. STUDY DESIGN:  Using commercial and Medicaid claims databases, infants born between July 1, 2011 and June 30, 2016 were categorized as preterm or term...
June 19, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29910465/neural-breathing-patterns-in-preterm-newborns-supported-with-non-invasive-neurally-adjusted-ventilatory-assist
#7
Fermín García-Muñoz Rodrigo, Lourdes Urquía Martí, Gloria Galán Henríquez, Sonia Rivero Rodríguez, Alberto Hernández Gómez
OBJECTIVE: To characterize the neural breathing pattern in preterm infants supported with non-invasive neurally adjusted ventilatory assist (NIV-NAVA). STUDY DESIGN: Single-center prospective observational study. The electrical activity of the diaphragm (EAdi) was periodically recorded in 30-second series with the Edi catheter and the Servo-n software (Maquet, Solna, Sweden) in preterm infants supported with NIV-NAVA. The EAdiPeak , EAdiMin , EAdiTonic , EAdiPhasic , neural inspiratory, and expiratory times (nTi and nTe) and the neural respiratory rate (nRR) were calculated...
June 18, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29910162/corpus-callosum-and-cerebellar-vermis-size-in-very-preterm-infants-relationship-to-long-term-neurodevelopmental-outcome
#8
Po-Ming Wu, Hsin-I Shih, Wen-Hao Yu, Li-Wen Chen, Lie-Chuan Wang, Chao-Ching Huang, Yi-Fang Tu
BACKGROUND: The neonatal changes of corpus callosum or cerebellar volume in preterm infants have been shown to link with abnormal mentality and motor disability in early childhood. This study aims to predict the long-term neurological outcomes by measuring these changes on neonatal brain ultrasound in preterm infants. METHODS: Our cohort consisted of infants aged below 32 weeks' gestation with very low birth body weights who completed neuro-assessments at 5 years of age...
June 1, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29902195/theoretical-open-loop-model-of-respiratory-mechanics-in-the-extremely-preterm-infant
#9
Laura Ellwein Fix, Joseph Khoury, Russell R Moores, Lauren Linkous, Matthew Brandes, Henry J Rozycki
Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to their markedly increased chest wall compliance that does not provide enough structure against which the forces of inhalation can generate sufficient pressure. To address the continued challenge of studying treatments in this fragile population, we developed a nonlinear lumped-parameter respiratory system mechanics model of the extremely preterm infant that incorporates nonlinear lung and chest wall compliances and lung volume parameters tuned to this population...
2018: PloS One
https://www.readbyqxmd.com/read/29900526/transplacental-versus-direct-fetal-corticosteroid-treatment-for-accelerating-fetal-lung-maturation-where-there-is-a-risk-of-preterm-birth
#10
REVIEW
Debby P Utama, Caroline A Crowther
BACKGROUND: Despite major advances in medical technology, the incidence of preterm birth remains high. The use of antenatal corticosteroid administered transplacentally, by intramuscular injection to women at risk of preterm birth, has reduced the incidence of respiratory distress syndrome and increased the survival rates of preterm infants. However, this intervention also comes with its own risks and side effects. Animal studies and early studies in pregnant women at risk of preterm birth have reported the use of an alternative route of administration, by direct intramuscular injection of corticosteroid into the fetus under ultrasound guidance, in an attempt to minimise the side-effect profile...
June 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29898763/non-invasive-high-frequency-oscillatory-ventilation-versus-nasal-continuous-positive-airway-pressure-in-preterm-infants-with-respiratory-distress-syndrome-study-protocol-for-a-multi-center-prospective-randomized-controlled-trial
#11
Xing-Wang Zhu, Yuan Shi, Li-Ping Shi, Ling Liu, Jiang Xue, Rangasamy Ramanathan
BACKGROUND: Invasive mechanical ventilation (IMV) is associated with the development of adverse pulmonary and non-pulmonary outcomes in very premature infants. Various modes of non-invasive respiratory support are increasingly being used to decrease the incidence of bronchopulmonary dysplasia. The aim of this trial is to compare the effect of non-invasive high-frequency oscillatory ventilation (NHFOV) and nasal continuous positive airway pressure (NCPAP) in preterm infants with respiratory distress syndrome (RDS) as a primary non-invasive ventilation support mode...
June 14, 2018: Trials
https://www.readbyqxmd.com/read/29894475/neonatal-factors-related-to-center-variation-in-the-incidence-of-late-onset-circulatory-collapse-in-extremely-preterm-infants
#12
Yume Suzuki, Yumi Kono, Takahiro Hayakawa, Hironori Shimozawa, Miyuki Matano, Yukari Yada
BACKGROUND: Although late-onset circulatory collapse (LCC) is widely recognized in Japan, its etiology and the reason for center variation in its incidence remain unclear. This study's objectives were to identify the perinatal and neonatal factors related to LCC and to estimate the factors related to the center variation in the incidence of LCC. METHODS: Extremely preterm infants born between 2008 and 2012 who were registered in the database of the Neonatal Research Network, Japan were retrospectively analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29894309/torso-shape-detection-to-improve-lung-monitoring
#13
Serena de Gelidi, Nima Seifnaraghi, Andy Bardill, Andrew Tizzard, Yu Wu, Erich Sorantin, Sven Nordebo, Andreas Demosthenous, Richard H Bayford
Newborns with lung immaturity often require continuous monitoring and treatment of their lung ventilation in intensive care units, especially if born preterm. Recent studies indicate that Electrical Impedance Tomography (EIT) is feasible in newborn
 infants and children, and can quantitatively identify changes in regional lung aeration and ventilation following alterations to respiratory conditions. Information on the patient-specic shape of the torso and its role in minimizing the artefacts in the
 reconstructed images can improve the accuracy of the clinical parameters obtained from EIT...
June 12, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29887608/early-diastolic-dysfunction-and-respiratory-morbidity-in-premature-infants-an-observational-study
#14
Neidin Bussmann, Colm Breatnach, Philip T Levy, Naomi McCallion, Orla Franklin, Afif El-Khuffash
OBJECTIVE: To test if diastolic dysfunction measured on day one of age is associated with the need for invasive ventilation in preterm infants. STUDY DESIGN: We conducted a retrospective observational tissue Doppler echocardiographic study over the first 12 h of age for infants born <32 weeks who were invasively ventilated, and infants on continuous positive pressure ventilation (CPAP). RESULTS: One hundred and eighty-three infants were included (27 ± 2 weeks and 999 ± 296 g)...
June 11, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29886779/does-intact-umbilical-cord-milking-increase-infection-rates-in-preterm-infants-with-premature-prolonged-rupture-of-membranes
#15
Juan Li, Bo Yu, Wei Wang, Luo, Qian-Ling Dai, Xiao-Qin Gan
OBJECTIVE: To investigate whether intact umbilical cord milking (I-UCM) can aggravate infection or result in other undesirable complications in preterm infants with premature prolonged rupture of membranes (PPROM). METHODS: Neonates vaginally delivered between 28 and 37 weeks' gestation and complicated by PPROM before birth were randomly divided into two groups according to the cord clamping procedure: I-UCM before clamping and immediate cord clamping (ICC). Various parameters of the study participants were compared between the two groups...
June 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29883983/the-relationship-of-assisted-reproductive-technology-on-perinatal-outcomes-in-triplet-gestations
#16
Jaimin S Shah, Tania Roman, Oscar A Viteri, Ziad A Haidar, Alejandra Ontiveros, Baha M Sibai
OBJECTIVE:  To assess whether assisted reproductive technology (ART) is associated with increased risk of adverse perinatal outcomes in triplet gestations compared with spontaneous conception. STUDY DESIGN:  Secondary analysis of a multicenter randomized trial for the prevention of preterm birth in multiple gestations. Triplets delivered at ≥ 24 weeks were studied. The primary outcome was the rate of composite neonatal morbidity (CNM) that included one or more of the following: bronchopulmonary dysplasia, respiratory distress syndrome, necrotizing enterocolitis, culture proven sepsis, pneumonia, retinopathy of prematurity, intraventricular hemorrhage, periventricular leukomalacia, or perinatal death...
June 8, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29881640/incidence-and-risk-factors-for-retinopathy-of-prematurity-a-retrospective-cohort-study
#17
André Moraes Freitas, Ricardo Mörschbächer, Mariana R Thorell, Ernani Luis Rhoden
Background and objectives: Advances in neonatal care promoted increased survival rates of preterm infants, with a consequent increase in the number of children affected by retinopathy of prematurity (ROP). This study estimates the incidence of ROP and evaluates potential risk factors associated. Methods: A retrospective cohort study of preterm infants born in a tertiary neonatal intensive care unit was conducted from March 2005 to August 2015. Six hundred and thirty-nine newborns were included based on the following criteria: infants born with less than 32 weeks' gestation or birth weight below 1500 g; or neonates born with 32-37 weeks' gestation or birth weight above 1500 g and any of the following associated: multiple gestation, respiratory distress syndrome, sepsis, blood transfusions or intraventricular hemorrhage...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29875829/does-the-sex-of-the-preterm-baby-affect-respiratory-outcomes
#18
REVIEW
Sarah J Kotecha, John Lowe, Sailesh Kotecha
Being born very preterm is associated with later deficits in lung function and an increased rate of respiratory symptoms compared with term-born children. The rates of early respiratory infections are higher in very preterm-born subjects, which may independently lead to deficits in lung function in later life. As with very preterm-born children, deficits in lung function, increased respiratory symptoms and an increased risk of respiratory infections in early life are observed in late -preterm-born children...
June 2018: Breathe
https://www.readbyqxmd.com/read/29871689/impact-of-family-integrated-care-on-infants-clinical-outcomes-in-two-children-s-hospitals-in-china-a-pre-post-intervention-study
#19
Shi-Wen He, Yue-E Xiong, Li-Hui Zhu, Bo Lv, Xi-Rong Gao, Hua Xiong, Huan Wang, Hua-Rong Shi, Jos M Latour
BACKGROUND: Most Neonatal Intensive Care Units (NICUs) in China have restricted visiting policies for parents. This also implicates that parents are not involved in the care of their infant. Family Integrated Care (FIC), empowering parents in direct care delivery and decisions, is becoming the standard in NICUs in many countries and can improve quality-of-life and health outcomes of preterm infants. The aim of this study was to evaluate the impact of a FIC intervention on the clinical outcomes of preterm infants with Bronchopulmonary Dysplasia (BPD)...
June 5, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29862364/aquaporine-5-and-epithelial-sodium-channel-%C3%AE-subunit-gene-expression-in-gastric-aspirates-in-human-term-newborns
#20
Fabiola Castorena-Torres, Mario René Alcorta-García, Víctor Javier Lara-Díaz
Both transient tachypnea of the newborn and neonatal respiratory distress syndrome have been associated with changes in gene expression of aquaporine-5 (AQP5) and the β subunit of the epithelial sodium channel (β-ENaC) in the respiratory epithelium. Gastric aspirate (GA) obtained immediately after birth could represent a new source for gene expression analysis for these respiratory diseases. The aims of this study were to determine the feasibility of estimating AQP5 and β-ENaC gene expression in exfoliated respiratory epithelial cells from the GA of term neonates, and to compare the values with those found in scraped nasal epithelial cells, previously validated as a surrogate for distal lung epithelium in terms of ionic channel activity...
April 2018: Heliyon
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