keyword
MENU ▼
Read by QxMD icon Read
search

Elderly and influenza

keyword
https://www.readbyqxmd.com/read/27910810/production-of-tnf-alpha-ex-vivo-is-predictive-of-an-immune-response-to-flu-vaccination-in-a-frail-elderly-population
#1
Frédéric Bloch, Bénédicte Charmeteau, Michael Tovey, Jean-François Meritet, Corinne Desaint, Odile Launay, Pierre Lebon
OBJECTIVE: To investigate the relationship between the response to influenza vaccination and the ability to produce proinflamatory cytokines in elderly subjects. METHODS: Whole blood samples from 25 elderly subjects collected before influenza vaccination were stimulated with the influenza vaccine in order to evaluate the secretion of five specific cytokines: TNFα, IFNα, IFNγ, IL2 and IL10. The results were correlated with the increased HAI antibody titres two weeks after vaccination...
September 1, 2016: European Cytokine Network
https://www.readbyqxmd.com/read/27893998/influenza-and-rhinovirus-viral-load-and-disease-severity-in-upper-respiratory-tract-infections
#2
Andrea Granados, Adriana Peci, Allison McGeer, Jonathan B Gubbay
BACKGROUND: The role of viral load in respiratory viral infection is unclear. It is proposed that the viral load of some, but not all respiratory viruses correlate with disease severity. OBJECTIVES: We aimed to determine if an association exists between viral loads among patients in ambulatory settings, compared to those requiring hospitalization/intensive care unit (ICU) admission with influenza A/H3N2, influenza B, or human rhinovirus (HRV); we also explored the impact of age, gender and co-detection of Streptococcus pneumoniae on patient setting...
November 22, 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27869969/influenza-vaccination-among-elderly-in-pelotas-rs-brazil-2014-a-population-based-study
#3
Rosália Garcia Neves, Suele Manjourany Silva Duro, Elaine Tomasi
OBJECTIVE: to describe the prevalence of individuals vaccinated against influenza and associated factors with vaccination among elderly; identify reasons for noncompliance and adverse events. METHODS: this was a cross-sectional study, conducted in the urban area of Pelotas-RS, Brazil, in 2014. RESULTS: out of 1,451 elderly, 71% got vaccinated; the highest prevalences were observed in the elderly with better economic status (PR=1.2 - 95%CI 1...
October 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27867430/evaluation-in-mouse-model-of-combined-virus-bacterial-vaccine-based-on-attenuated-influenza-a-h7n3-virus-and-the-group-b-streptococcus-recombinant-polypeptides
#4
Yulia A Desheva, Galina F Leontieva, Tatiana A Kramskaya, Tatiana A Smolonogina, Kornelia B Grabovskaya, Irina V Kiseleva, Larisa G Rudenko, Alexander N Suvorov
BACKGROUND: Secondary bacterial influenza complications are a common cause of excesses morbidity and mortality, which determines the need to develop means for specific prophylaxis. Group B streptococcal infection is especially common cause of pneumonia among children and the elderly with underlying conditions. Here we investigate in a mouse model the effects of combined intranasal immunization using live attenuated influenza vaccine and recombinant polypeptides based on group B Streptococcus surface proteins...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27846277/pneumococcal-conjugated-vaccine-reduces-the-high-mortality-for-community-acquired-pneumonia-in-the-elderly-an-italian-regional-experience
#5
Vincenzo Baldo, Silvia Cocchio, Tolinda Gallo, Patrizia Furlan, Pierantonio Romor, Chiara Bertoncello, Alessandra Buja, Tatjana Baldovin
BACKGROUND: Community-acquired pneumonia (CAP) is an important cause of illness and death worldwide, particularly among the elderly. Previous studies on the factors associated with mortality in patients hospitalized for CAP revealed a direct association between the type of microorganism involved, the characteristics of the patient and mortality. Vaccination status against pneumococcal disease was not considered. We conducted a retrospective analysis on the mortality rates after a first hospitalization for CAP in north-east Italy with a view to examining especially the role of anti-pneumococcal vaccination as a factor associated with pneumonia-related mortality at one year...
2016: PloS One
https://www.readbyqxmd.com/read/27832186/differences-in-influenza-vaccination-coverage-between-adult-immigrants-and-italian-citizens-at-risk-for-influenza-related-complications-a-cross-sectional-study
#6
Massimo Fabiani, Flavia Riccardo, Anteo Di Napoli, Lidia Gargiulo, Silvia Declich, Alessio Petrelli
BACKGROUND: Due to their increased vulnerability, immigrants are considered a priority group for communicable disease prevention and control in Europe. This study aims to compare influenza vaccination coverage (IVC) between regular immigrants and Italian citizens at risk for its complications and evaluate factors affecting differences. METHODS: Based on data collected by the National Institute of Statistics during a population-based cross-sectional survey conducted in Italy in 2012-2013, we analysed information on 42,048 adult residents (≥ 18 years) at risk for influenza-related complications and with free access to vaccination (elderly residents ≥ 65 years and residents with specific chronic diseases)...
2016: PloS One
https://www.readbyqxmd.com/read/27832114/seasonal-influenza-a-h1n1pdm09-virus-and-severe-outcomes-a-reason-for-broader-vaccination-in-non-elderly-at-risk-people
#7
Elisa Minchole, Ana L Figueredo, Manuel Omeñaca, Carolina Panadero, Laura Royo, Jose J Vengoechea, Sergio Fandos, Francisco de Pablo, Salvador Bello
BACKGROUND: Recent pandemics of influenza A H1N1pdm09 virus have caused severe illness, especially in young people. Very few studies on influenza A H1N1pdm09 in post-pandemic periods exist, and there is no information on the severity of both seasonal influenza A(H1N1) and A(H3N2) from the same season, adjusting for potential confounders, including vaccine. METHODS AND RESULTS: We performed a retrospective observational study of adults hospitalized during the 2014 season with influenza A(H1N1) or A(H3N2)...
2016: PloS One
https://www.readbyqxmd.com/read/27823899/influenza-vaccination-and-the-endurance-against-air-pollution-among-elderly-with-acute-coronary-syndrome
#8
Ching-Hui Huang, Day-Yu Chao, Chao-Chun Wu, Shu-Yun Hsu, Maw-Soan Soon, Chia-Chu Chang, Chew-Teng Kor, Wan-Tzu Chang, Ie-Bin Lian
OBJECTIVE: Air pollution, weather condition and influenza are known risk factors of acute coronary syndrome (ACS) among elderly people. The influenza vaccine (IV) has been shown to reduce major cardiovascular events. The purpose of this study was to compare resistance to air pollution and weather factors causing ACS between vaccinated and less-vaccinated elderly people. METHODS: A case-crossover design was applied to 1835 elderly ACS patients who were obtained from the 1-million sample of Taiwan National Health Insurance Research Data with inclusion criteria: (1) the first diagnosis of ACS was in cold season and at age 68 or more, (2) had received the free IV program at least once during the period 3years before the ACS...
December 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27816309/-the-seasonal-flu-vaccination-among-caregivers-in-geriatric-units-up-to-date
#9
E Contal, A Putot, M Dipanda, S Perrin, S Asgassou, H Sordet-Guépet, P Manckoundia
BACKGROUND: Flu vaccinations for healthcare professionals seems to be one of the most effective preventive actions in the face of a disease that carries a high risk of a potentially serious nosocomial epidemic in a geriatric environment. The aim of this study was to take stock of the flu vaccination status among caregivers in the geriatric units and to understand the reasons for their reluctance to be vaccinated, in order to put forward proposals to improve vaccination coverage. METHOD: A literature search of articles published since 2000 in the area of geriatrics, infectious diseases or pneumology was mainly conducted on PubMed using the keywords "caregivers", "elderly", "flu", "influenza", "nosocomial" and "vaccination"...
December 2016: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/27814377/antibody-persistence-and-booster-responses-to-split-virion-h5n1-avian-influenza-vaccine-in-young-and-elderly-adults
#10
Rajeka Lazarus, Sarah Kelly, Matthew D Snape, Corinne Vandermeulen, Merryn Voysey, Karel Hoppenbrouwers, Annick Hens, Pierre Van Damme, Stephanie Pepin, Isabel Leroux-Roels, Geert Leroux-Roels, Andrew J Pollard
: Avian influenza continues to circulate and remains a global health threat not least because of the associated high mortality. In this study antibody persistence, booster vaccine response and cross-clade immune response between two influenza A(H5N1) vaccines were compared. Participants aged over 18-years who had previously been immunized with a clade 1, A/Vietnam vaccine were re-immunized at 6-months with 7.5 μg of the homologous strain or at 22-months with a clade 2, alum-adjuvanted, A/Indonesia vaccine...
2016: PloS One
https://www.readbyqxmd.com/read/27802078/immunogenicity-of-trivalent-influenza-vaccines-in-patients-with-chronic-kidney-disease-undergoing-hemodialysis-mf59-adjuvanted-versus-non-adjuvanted-vaccines
#11
Ji Yun Noh, Joon Young Song, Won Suk Choi, Jacob Lee, Yu Bin Seo, Young Joo Kwon, Gang Jee Ko, Dae Ryong Cha, Young Sun Kang, Young-Ki Lee, Hee Jin Cheong, Woo Joo Kim
BACKGROUNDS: Patients with chronic kidney disease (CKD) are at an increased risk of morbidity and mortality from influenza. However, the immunogenicity of influenza vaccine is known to be attenuated in these patients. In this study, the immunogenicity of MF59-adjuvanted and non-adjuvanted trivalent influenza vaccines was compared in CKD patients undergoing hemodialysis (HD). METHODS: During 2013-2014, 179 CKD patients undergoing HD participated in the study. The patients were randomized into either MF59-adjuvanted vaccine group or non-adjuvanted vaccine group and were immunized with the respective vaccine...
November 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27799521/vaccination-strategies-against-respiratory-syncytial-virus
#12
Dan Yamin, Forrest K Jones, John P DeVincenzo, Shai Gertler, Oren Kobiler, Jeffrey P Townsend, Alison P Galvani
Respiratory syncytial virus (RSV) is the most common cause of US infant hospitalization. Additionally, RSV is responsible for 10,000 deaths annually among the elderly across the United States, and accounts for nearly as many hospitalizations as influenza. Currently, several RSV vaccine candidates are under development to target different age groups. To evaluate the potential effectiveness of age-specific vaccination strategies in averting RSV incidence, we developed a transmission model that integrates data on daily infectious viral load and changes of behavior associated with RSV symptoms...
November 15, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27793117/predictors-of-influenza-among-older-adults-in-the-emergency-department
#13
Po-Po Lam, Brenda L Coleman, Karen Green, Jeff Powis, David Richardson, Kevin Katz, Bjug Borgundvaag, Telisha Smith-Gorvie, Jeffrey C Kwong, Susan J Bondy, Allison McGeer
BACKGROUND: Diagnosis of influenza in older adults may be complicated by atypical presentations or when patients present with complications of an underlying illness. We aimed to identify clinical characteristics and epidemiological factors associated with influenza among community-dwelling adults aged ≥60 years presenting to emergency departments. METHODS: We identified patients with influenza-compatible chief complaints presenting to emergency departments of six acute care hospitals in Ontario, Canada during the 2011/12 and 2012/13 influenza seasons...
October 28, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27788517/the-preventive-effect-of-the-traditional-japanese-herbal-medicine-hochuekkito-against-influenza-a-virus-via-autophagy-in-vitro
#14
Keita Takanashi, Katsuaki Dan, Sho Kanzaki, Hideki Hasegawa, Kenji Watanabe, Kaoru Ogawa
BACKGROUND: Hochuekkito (HKT), a traditional Japanese herbal medicine, enhances the immunity of elderly or weak individuals. It is also known to have preventive effects against influenza clinically. However, the detailed mechanisms of the preventive effects have not been clarified. We examined the relationship between the preventive effects of HKT and autophagy, a known stress response and quality control mechanism, using Madin-Darby canine kidney cells and influenza A/PR/8/34 (H1N1) virus...
October 28, 2016: Pharmacology
https://www.readbyqxmd.com/read/27777781/impact-of-pharmacists-as-immunizers-on-influenza-vaccination-coverage-in-the-community-setting-in-nova-scotia-canada-2013-2015
#15
Jennifer E Isenor, Jessica L Killen, Beverly A Billard, Shelly A McNeil, Donna MacDougall, Beth A Halperin, Kathryn L Slayter, Susan K Bowles
BACKGROUND: Annual immunization is the most effective way to prevent influenza and its associated complications. However, optimal immunization rates are not being met in Nova Scotia, Canada. Additional providers, such as pharmacists, may improve access and convenience to receive vaccines. Pharmacists began immunizing patients 5 years of age and older within the publicly funded universal influenza vaccination program during the 2013-2014 influenza season. The objective of this study was to evaluate influenza immunization coverage rates before and after pharmacists in Nova Scotia gained authority to immunize as part of the publicly funded universal influenza vaccination program...
2016: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/27776172/fatal-cases-of-seasonal-influenza-in-russia-in-2015-2016
#16
T Ilyicheva, A Durymanov, I Susloparov, N Kolosova, N Goncharova, S Svyatchenko, O Petrova, A Bondar, V Mikheev, A Ryzhikov
The influenza epidemic in 2015-2016 in Russia is characterized by a sharp increase of influenza cases (beginning from the second week of 2016) with increased fatalities. Influenza was confirmed in 20 fatal cases registered among children (0-10 years), in 5 cases among pregnant women, and in 173 cases among elderly people (60 years and older). Two hundred and ninety nine people died from influenza were patients with some chronic problems. The overwhelming majority among the deceased (more than 98%) were not vaccinated against influenza...
2016: PloS One
https://www.readbyqxmd.com/read/27746159/modulation-of-host-defence-against-bacterial-and-viral-infections-by-omega-3-polyunsaturated-fatty-acids
#17
REVIEW
Marie-Odile Husson, Delphine Ley, Céline Portal, Madeleine Gottrand, Thomas Hueso, Jean-Luc Desseyn, Frédéric Gottrand
OBJECTIVES: Although n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) are used widely in the treatment of chronic inflammatory diseases, their effect in infectious disease requires a particular attention. METHODS: The present article discusses their anti-inflammatory and immune properties involved in the host defence and presents a systematic review of the effects of their oral administration on the prevention and outcome of experimental and clinical infections...
December 2016: Journal of Infection
https://www.readbyqxmd.com/read/27745951/seasonal-influenza-vaccination-in-china-landscape-of-diverse-regional-reimbursement-policy-and-budget-impact-analysis
#18
Juan Yang, Katherine E Atkins, Luzhao Feng, Mingfan Pang, Yaming Zheng, Xinxin Liu, Benjamin J Cowling, Hongjie Yu
BACKGROUND: To explore the current landscape of seasonal influenza vaccination across China, and estimate the budget of implementing a national "free-at-the-point-of-care" vaccination program for priority populations recommended by the World Health Organization. METHODS: In 2014 and 2016, we conducted a survey across provincial Centers for Disease Control and Prevention to collect information on regional reimbursement policies for influenza vaccination, estimated the national uptake using distributed doses of influenza vaccines, and evaluated the budget using population size and vaccine cost obtained from official websites and literatures...
October 13, 2016: Vaccine
https://www.readbyqxmd.com/read/27740538/economic-outcomes-of-influenza-in-hospitalized-elderly-with-and-without-icu-admission
#19
Yik-Kei Chan, Rity Yk Wong, Margaret Ip, Nelson Ls Lee, Joyce Hs You
BACKGROUND: To describe direct medical costs of influenza in hospitalized elderly, with and without intensive care unit (ICU) admission, during the 2014-2015 season in Hong Kong. METHODS: A retrospective study was conducted in 110 inpatients aged ≥65 years with laboratory-confirmed influenza treated by antiviral therapy during season 2014-2015 in a tertiary hospital. Resource utilization of influenza-related diagnostic and laboratory tests, medications for influenza treatment, usage of general medical ward and ICU during the influenza-related length of hospital stay (IR-LOS) were collected...
October 14, 2016: Antiviral Therapy
https://www.readbyqxmd.com/read/27726802/respiratory-rna-viruses
#20
Richard L Hodinka
Acute upper and lower respiratory infections are a major public health problem and a leading cause of morbidity and mortality worldwide. At greatest risk are young children, the elderly, the chronically ill, and those with suppressed or compromised immune systems. Viruses are the predominant cause of respiratory tract illnesses and include RNA viruses such as respiratory syncytial virus, influenza virus, parainfluenza virus, metapneumovirus, rhinovirus, and coronavirus. Laboratory testing is required for a reliable diagnosis of viral respiratory infections, as a clinical diagnosis can be difficult since signs and symptoms are often overlapping and not specific for any one virus...
August 2016: Microbiology Spectrum
keyword
keyword
116340
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"