keyword
https://read.qxmd.com/read/38518621/nano-palladium-decorated-bismuth-sulfide-microspheres-on-a-disposable-electrode-integrated-with-smartphone-based-electrochemical-detection-of-nitrite-in-food-samples
#21
JOURNAL ARTICLE
Kiattisak Promsuwan, Jenjira Saichanapan, Asamee Soleh, Kasrin Saisahas, Kritsada Samoson, Sangay Wangchuk, Proespichaya Kanatharana, Panote Thavarungkul, Warakorn Limbut
Nitrite (NO2 - ) is widely used as an additive to extend the shelf life of food products. Excessive nitrite intake not only causes blood-related diseases but also has the potential risk of causing cancers. A disposable screen-printed electrode was modified with nano‑palladium decorated bismuth sulfide microspheres (nanoPd@Bi2 S3 MS/SPE), and integrated with a smartphone-interfaced potentiostat to develop a portable, electrochemical nitrite sensor. NanoPd@Bi2 S3 MS was prepared by the hydrothermal reduction of a Bi2 S3 MS and Pd2+ dispersion and drop cast on the SPE...
March 13, 2024: Food Chemistry
https://read.qxmd.com/read/38517595/pulmonary-ct-perfusion-robustly-measures-cardiac-output-in-the-context-of-multilevel-pulmonary-occlusion-a-porcine-study
#22
JOURNAL ARTICLE
Diogo Silva, Thomas Muders, Karin Wodack, Christian Putensen, Steffen Leonhardt, Robert Siepmann, Benjamin Hentze, Sebastian Reinartz
BACKGROUND: To validate pulmonary computed tomography (CT) perfusion in a porcine model by invasive monitoring of cardiac output (CO) using thermodilution method. METHODS: Animals were studied at a single center, using a Swan-Ganz catheter for invasive CO monitoring as a reference. Fifteen pigs were included. Contrast-enhanced CT perfusion of the descending aorta and right and left pulmonary artery was performed. For variation purposes, a balloon catheter was inserted to block the contralateral pulmonary vascular bed; additionally, two increased CO settings were created by intravenous administration of catecholamines...
March 22, 2024: European Radiology Experimental
https://read.qxmd.com/read/38517386/polymer-microspheres-copolymerized-with-deep-red-fluorescent-molecules-as-a-label-for-lateral-flow-immunochromatography
#23
JOURNAL ARTICLE
Jiaxing Han, Qingyu Lv, Daoxiang Su, Lucheng Chen, Shihong Zhu, Qi Liu, Yongqiang Jiang, Xiao Li, Yong Jiang, Zhifei Wang
The development of fluorescently labeled microspheres is a critical aspect of advancing the technology of lateral flow immunochromatography (LFIA) for biological detection. Nevertheless, potential interference posed by the background fluorescence originating from the nitrocellulose (NC) membrane would significantly impact the sensitivity and accuracy of microsphere-based detection in LFIA. In this work, an attempt was made to extend the π-conjugated system and asymmetric structure of rhodamine fluorophore, resulting in the synthesis of dye molecules (RB2) incorporating double bonds, which can reach an absolute photoluminescence quantum yield (PLQY) of 30...
March 22, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38517309/hybrid-protein-microspheres-and-their-responsive-release-behaviors-and-inhibitory-effects-on-melanin-synthesis
#24
JOURNAL ARTICLE
Ee Taek Hwang, Yeahwa Yoon, Ka Ram Kim, Chan Hee Lee, Kyung Chan Jeon, Ji Ho Min, Jae Won Lee, Jangyong Kim
In this study, the formation of protein microspheres through lysosomal enzyme-assisted biomineralized crystallization was demonstrated. Spherical micro-sized hybrid CaCO3 constructs were synthesized and characterized using field-emission scanning electron microscopy equipped with energy-dispersive X-ray spectroscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, and particle size analysis. Additionally, parameters such as the Brunauer-Emmett-Teller surface area and single-point total pore volume, and adsorption/desorption analysis were used to investigate the mesoporous properties, which are advantageous for lysosomal enzyme (LE) loading...
March 22, 2024: Biomaterials Science
https://read.qxmd.com/read/38517127/preparation-of-a-long-lasting-tablet-of-spinosad-microspheres-and-its-residual-insecticidal-efficacy-against-the-yellow-fever-mosquito-aedes-aegypti-diptera-culicidae-larvae
#25
JOURNAL ARTICLE
Hongxiao Yu, Yunqi Li, Hong Wang, Lei Zhang, Penghui Suo, Tianyun Su, Qian Han
BACKGROUNDS: To provide a long-lasting formulation for spinosad (SP) targeting larval stages of Aedes aegypti (Linnaeus) and others alike, a SP tablet was developed based on microspheres, using polylactic acid as inside coating material. The microspheres were encapsulated using polyethylene glycol and 1-hexadecanol to form a sustained-release SP tablet. Micromorphology, active ingredient loading, structure identification, photolysis resistance, and biological activity were evaluated in this report...
March 22, 2024: Pest Management Science
https://read.qxmd.com/read/38516939/suppression-of-the-plasmon-quenching-effect-on-light-amplification-in-20-%C3%AE-m-diameter-plasmonic-whispering-gallery-mode-resonators-fabricated-from-bowl-shaped-organic-metal-thin-films
#26
JOURNAL ARTICLE
Minami Takaishi, Takeshi Komino, Akihiro Kameda, Kyosuke Togawa, Tokuji Yokomatsu, Kazusuke Maenaka, Hiroyuki Tajima
Bowl-shaped plasmonic whispering gallery mode (WGM) resonators were fabricated from a 10-nm-thick metal (Al, Ag, or Au) plasmonic layer that was covered with a 100-nm-thick 4,4'-bis( N -carbazolyl)-1,1'-biphenyl spacer layer and a 250-nm-thick 2,7-bis[9,9-di(4-methylphenyl)-fluoren-2-yl]-9,9-di(4-methylphenyl)fluorene light-emitting layer; the layer structure was grown on a 20-μm-diameter silica microsphere. When compared with a reference structure without the plasmonic layer, the resonators, which included either Al or Ag, showed almost the same threshold excitation intensities for generation of amplified spontaneous emission (ASE)...
March 22, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38514835/simulation-of-interfacial-debonding-in-hollow-particle-reinforced-composites-with-vcfem
#27
JOURNAL ARTICLE
Zhiyi Wang, Rui Zhang
The addition of hollow glass microsphere into composites is a method to improve mechanical properties. However, the interfacial debonding of hollow microsphere inevitably causes a decrease in the mechanical properties of the material, which ultimately leads to the failure of the composites. In the numerical simulation of such hollow particle-reinforced composites, the ordinary displacement finite element requires a large number of meshes, which undoubtedly greatly increases the computational cost. In this paper, a new VCFEM is proposed to solve this problem by establishing a two-dimensional Voronoi cell finite element model, deriving the residual energy generalized function of hollow particle-reinforced composites, and calculating the interface debonding...
March 22, 2024: Scientific Reports
https://read.qxmd.com/read/38508565/fabrication-and-characterization-of-a-multi-functional-gbr-membrane-of-gelatin-chitosan-for-osteogenesis-and-angiogenesis
#28
JOURNAL ARTICLE
Xiaofei Hu, Yuzhu He, Yunmeng Tong, Na Sun, Guowu Ma, Huiying Liu, Ni Kou
Guided bone regeneration (GBR) membranes are widely used to treat bone defects. In this study, sequential electrospinning and electrospraying techniques were used to prepare a dual-layer GBR membrane composed of gelatin (Gel) and chitosan (CS) containing simvastatin (Sim)-loaded poly(lactic-co-glycolic acid) (PLGA) microspheres (Sim@PLGA/Gel-CS). As a GBR membrane, Sim@PLGA/Gel-CS could act as a barrier to prevent soft tissue from occupying regions of bone tissue. Furthermore, compared with traditional GBR membranes, Sim@PLGA/Gel-CS played an active role on stimulating osteogenesis and angiogenesis...
March 18, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38508556/polysaccharide-hydrogel-containing-silver-nanoparticle-catechol-microspheres-with-photothermal-antibacterial-and-anti-inflammatory-activities-for-infected-wounds-repair
#29
JOURNAL ARTICLE
An-Le Yang, Shi-Bin Sun, Lian-Yi Qu, Xue-Yan Li, Jiang-Long Liu, Fang Zhou, Ying-Jun Xu
Anti-infection hydrogels have recently aroused enormous attraction, particularly in the treatment of chronic wounds. Herein, silver nanoparticle@catechol formaldehyde resin microspheres (Ag@CFRs) were fabricated by one-step hydrothermal method and subsequently encapsulated in hydrogels which were developed by Schiff base reaction between aldehyde groups in oxidized hyaluronic acid and amino groups in carboxymethyl chitosan. The developed polysaccharide hydrogel exhibited microporous structure, high swelling capacity, favorable mechanical strength, enhanced tissue adhesion and photothermal activities...
March 18, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38507684/design-of-bombyx-mori-b-mori-silk-fibroin-microspheres-for-developing-biosafe-sunscreen
#30
JOURNAL ARTICLE
Yecheng Wang, Mei Yang, Jie Wang, Yajun Shuai, Zongpu Xu, Quan Wan, Suting Zhong, Chuanbin Mao, Weidong Ping, Mingying Yang
Sunscreens play a crucial role in protecting the skin from ultraviolet (UV) damage. However, present commercial sunscreens have a tendency to generate free radicals in the UV window, resulting in serious inflammatory responses and health problems. In this study, we demonstrate that silk fibroin microspheres (SFMPs) assembled from regenerated silk fibroin (SF) could scavenge free radicals while preventing UV irradiation and thus present a promising sunscreen. The SFMP reflected more UV light than SF and presented a higher stability than that of organic commercial sunscreens...
March 20, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38505834/video-microscopy-based-automated-trajectory-determination
#31
JOURNAL ARTICLE
Christopher Tyson, Santosh Gaire, Ian Pegg, Abhijit Sarkar
We present a method for tracking densely clustered, high-velocity, indistinguishable objects being spawned at a high rate and moving in a directed force field using only object centroids as inputs and no other image information. The algorithm places minimal restrictions on the velocities or accelerations of the objects being tracked and uses a methodology based on a scoring function and a backtracking refinement process. This combination leads to successful tracking of hundreds of particles in challenging environments even when the displacement of the individual objects at successive times approaches the separation between neighboring objects in any one frame...
June 12, 2024: Biophys Rep (N Y)
https://read.qxmd.com/read/38500414/bioactive-moldable-click-chemistry-polymer-cement-with-nano-hydroxyapatite-and-growth-factor-enhanced-posterolateral-spinal-fusion-in-a-rabbit-model
#32
JOURNAL ARTICLE
Xifeng Liu, Maria D Astudillo Potes, Vitalii Serdiuk, Babak Dashtdar, Areonna C Schreiber, Asghar Rezaei, A Lee Miller, Abdelrahman M Hamouda, Mahnoor Shafi, Benjamin D Elder, Lichun Lu
Spinal injuries or diseases necessitate effective fusion solutions, and common clinical approaches involve autografts, allografts, and various bone matrix products, each with limitations. To address these challenges, we developed an innovative moldable click chemistry polymer cement that can be shaped by hand and self-cross-linked in situ for spinal fusion. This self-cross-linking cement, enabled by the bioorthogonal click reaction, excludes the need for toxic initiators or external energy sources. The bioactivity of the cement was promoted by incorporating nanohydroxyapatite and microspheres loaded with recombinant human bone morphogenetic protein-2 and vascular endothelial growth factor, fostering vascular induction and osteointegration...
March 18, 2024: ACS Applied Bio Materials
https://read.qxmd.com/read/38497428/preparation-of-dyed-polymer-microspheres-by-a-physical-chemical-dual-binding-method-and-their-application-in-lateral-flow-immunoassay
#33
JOURNAL ARTICLE
Jiatong Li, Pengfei Zhang, Qianrui Xu, Yingrui Nie, Shimin Shao, Zhifei Wang, Yong Jiang
Lateral flow immunoassay (LFIA) has shown great competitiveness in point-of-care testing due to its flexibility and simplicity. Dyed polymer microspheres are one of the most widely used marker particles for signal presentation as they are very convenient for visual interpretation, which is one of the most attractive features of LFIA. The color intensity, as the most critical factor, is directly related to the visual effect. In this work, a physical-chemical dual-binding strategy was proposed for the preparation of functionalized dyed microspheres...
March 18, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38496762/intestinal-organoid-modeling-bridging-the-gap-from-experimental-model-to-clinical-translation
#34
REVIEW
Taotao Liu, Xiaoqi Li, Hao Li, Jingjing Qin, Hui Xu, Jun Wen, Yaqin He, Cao Zhang
The 3D culture of intestinal organoids entails embedding isolated intestinal crypts and bone marrow mesenchymal stem cells within a growth factor-enriched matrix gel. This process leads to the formation of hollow microspheres with structures resembling intestinal epithelial cells, which are referred to as intestinal organoids. These structures encompass various functional epithelial cell types found in the small intestine and closely mimic the organizational patterns of the small intestine, earning them the name "mini-intestines"...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38496440/comparison-of-a-novel-potentiator-of-cftr-channel-activity-to-ivacaftor-in-ameliorating-mucostasis-caused-by-cigarette-smoke-in-primary-human-bronchial-airway-epithelial-cells
#35
Adrian Constantin Tanjala, Jia Xin Jiang, Paul D W Eckford, Mohabir Ramjeesingh, Canhui Li, Ling Jun Huan, Gabrielle Langeveld, Claire Townsend, Daniel V Paone, Jakob Busch-Petersen, Roman Pekhletski, LiPing Tang, Vamsee Raju, Steven M Rowe, Christine E Bear
BACKGROUND: Cystic Fibrosis causing mutations in the gene CFTR , reduce the activity of the CFTR channel protein, and leads to mucus aggregation, airway obstruction and poor lung function. A role for CFTR in the pathogenesis of other muco-obstructive airway diseases such as Chronic Obstructive Pulmonary Disease (COPD) has been well established. The CFTR modulatory compound, Ivacaftor (VX-770), potentiates channel activity of CFTR and certain CF-causing mutations and has been shown to ameliorate mucus obstruction and improve lung function in people harbouring these CF-causing mutations...
March 4, 2024: bioRxiv
https://read.qxmd.com/read/38496052/tunable-high-entropy-lanthanide-oxide-microspheres-via-confined-electroprecipitation-in-emulsion-droplet-scaffolds
#36
JOURNAL ARTICLE
Charles H Laber, Austin R Scircle, Zachary P Mouton, Travis Thornell, Ashly Antony, Jonah W Jurss, Matthew W Glasscott
Emergent high entropy nanomaterials and their associated complex surface structure hold promise to unlock unique catalytic intermediate pathways and photonic/plasmonic interactions; however, synthetic strategies to tune the size, morphological, and stoichiometric properties remain limited. This work demonstrates a confined electro-precipitation mechanism for the formation of tunable, high-entropy oxide microspheres within emulsion droplet scaffolds. This mechanism complements a traditional confined electrodeposition mechanism and explains the previously observed anomalous formation of thermodynamically unfavorable particles, including lanthanide species...
March 13, 2024: ACS Mater Au
https://read.qxmd.com/read/38495715/dynamic-speckle-illumination-wide-field-fluorescence-microscopy-with-actively-optical-manipulation-of-rotational-angles
#37
JOURNAL ARTICLE
Jun Yin, Yan Miao, Ruijing Liang, Haoyi Hou, Chuanxin Teng, Lingyao Yu
We present a dynamic speckle illumination wide-field fluorescence microscopy (DSIWFM) combined with a line optical tweezers (LOTs) for rotational fluorescence sectioning imaging. In this method, large polystyrene fluorescent microspheres are stably trapped with LOTs, and precisely manipulated to rotate around a specific rotation axis. During the rotation process, multiple raw fluorescence images of trapped microspheres are obtained with dynamic speckle illumination. The root-mean-square (RMS) algorithm is used to extract the drastically changing fluorescent signals in the focal plane to obtain the fluorescence sectioning images of the samples at various angles...
March 1, 2024: Biomedical Optics Express
https://read.qxmd.com/read/38492377/hierarchical-cowo-4-ni-x-fe-y-s-microspheres-bearing-crystalline-amorphous-interface-as-a-multifunctional-platform-for-outperformed-water-splitting-and-sensitive-hydrazine-sensing
#38
JOURNAL ARTICLE
Qi Qian, Chenxin Chen, Xuan Zheng, Qingxiang Wang, Feng Gao, Zehua Zou
Highly efficient and multifunctional electrocatalysts are of high value in energy transformation and electrochemical sensing. Herein, hierarchically architectured cobalt tungstate/nickel iron sulfide (CoWO4 /Nix Fey S) microspheres with a crystalline-amorphous interface have been prepared on bimetallic substrate of nickel-iron foam (NIF) by a two-step hydrothermal method. Electrochemical characterization shows that CoWO4 /Nix Fey S microspheres can boost the electrocatalytic activity effectively through the synergistic effect on the crystalline-amorphous interface...
March 9, 2024: Journal of Colloid and Interface Science
https://read.qxmd.com/read/38491852/metabolomics-based-effects-of-a-natural-product-on-remyelination-after-cerebral-ischemia-injury-via-gababr-pcreb-bdnf-pathway
#39
JOURNAL ARTICLE
Xiaodi Fan, Min Zhan, Wenting Song, Mingjiang Yao, Guangrui Wang, Tian Li, Yehao Zhang, Jianxun Liu
BACKGROUND: Yi-Qi-Tong-Luo Granules (YQTLs) is a natural compound of Traditional Chinese Medicine authorized by China Food and Drug Administration (CFDA). These granules are employed in the convalescent stage of cerebral infarction and render notable clinical efficacy. This study aims to uncover the underlying mechanisms of YQTLs on remyelination after cerebral ischemia injury. MATERIALS AND METHODS: We established cerebral ischemia model in rats using microsphere-induced multiple cerebral infarction (MCI)...
March 16, 2024: Neurorehabilitation and Neural Repair
https://read.qxmd.com/read/38490376/construction-of-phenolic-acids-grafted-chitosan-bioactive-microspheres-to-reduce-oxidation-and-iron-absorption-in-meat-digestion
#40
JOURNAL ARTICLE
Yafei Zhang, Xiaojing Tian, Kai Zhang, Kaixuan Zhao, Yang Wang, Chenwei Ma, Jingjing Guo, Wenhang Wang
Although iron in meat is an important trace element for human diet, its presence also induces postprandial oxidative stress and aggravates the condition of patients with iron overload. To overcome this situation, a type of new tunable Fe-absorption bioactive materials was constructed in this study. First, four phenolic acids (Caffeic acid, Gallic acid, Protocatechuic acid, Chlorogenic acid) were grafted onto chitosan. Then, the copolymers were prepared into micron-level microspheres by emulsification method, which were characterized in adsorption isotherms (Langmuir model), swelling behavior and digestion characteristics...
March 13, 2024: International Journal of Biological Macromolecules
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