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JOURNAL ARTICLE
Hayley S Clements, Emmanuel Do Linh San, Gareth Hempson, Birthe Linden, Bryan Maritz, Ara Monadjem, Chevonne Reynolds, Frances Siebert, Nicola Stevens, Reinette Biggs, Alta De Vos, Ryan Blanchard, Matthew Child, Karen J Esler, Maike Hamann, Ty Loft, Belinda Reyers, Odirilwe Selomane, Andrew L Skowno, Tshegofatso Tshoke, Diarrassouba Abdoulaye, Thierry Aebischer, Jesús Aguirre-Gutiérrez, Graham J Alexander, Abdullahi H Ali, David G Allan, Esther E Amoako, Samuel Angedakin, Edward Aruna, Nico L Avenant, Gabriel Badjedjea, Adama Bakayoko, Abraham Bamba-Kaya, Michael F Bates, Paul J J Bates, Steven R Belmain, Emily Bennitt, James Bradley, Chris A Brewster, Michael B Brown, Michelle Brown, Josef Bryja, Thomas M Butynski, Filipe Carvalho, Alan Channing, Colin A Chapman, Callan Cohen, Marina Cords, Jennifer D Cramer, Nadine Cronk, Pamela M K Cunneyworth, Fredrik Dalerum, Emmanuel Danquah, Harriet T Davies-Mostert, Andrew D de Blocq, Yvonne A De Jong, Terrence C Demos, Christiane Denys, Chabi A M S Djagoun, Thomas M Doherty-Bone, Marine Drouilly, Johan T du Toit, David A Ehlers Smith, Yvette C Ehlers Smith, Seth J Eiseb, Peter J Fashing, Adam W Ferguson, José M Fernández-García, Manfred Finckh, Claude Fischer, Edson Gandiwa, Philippe Gaubert, Jerome Y Gaugris, Dalton J Gibbs, Jason S Gilchrist, Jose M Gil-Sánchez, Anthony N Githitho, Peter S Goodman, Laurent Granjon, J Paul Grobler, Bonginkosi C Gumbi, Vaclav Gvozdik, James Harvey, Morgan Hauptfleisch, Firas Hayder, Emmanuel M Hema, Marna Herbst, Mariano Houngbédji, Brian J Huntley, Rainer Hutterer, Samuel T Ivande, Kate Jackson, Gregory F M Jongsma, Javier Juste, Blaise Kadjo, Prince K Kaleme, Edwin Kamugisha, Beth A Kaplin, Humphrey N Kato, Christian Kiffner, Duncan M Kimuyu, Robert M Kityo, N'goran G Kouamé, Marcel Kouete T, Aliza le Roux, Alan T K Lee, Mervyn C Lötter, Anne Mette Lykke, Duncan N MacFadyen, Gacheru P Macharia, Zimkitha J K Madikiza, Themb'alilahlwa A M Mahlaba, David Mallon, Mnqobi L Mamba, Claude Mande, Rob A Marchant, Robin A Maritz, Wanda Markotter, Trevor McIntyre, John Measey, Addisu Mekonnen, Paulina Meller, Haemish I Melville, Kevin Z Mganga, Michael G L Mills, Liaan Minnie, Alain Didier Missoup, Abubakr Mohammad, Nancy N Moinde, Bakwo Fils E Moise, Pedro Monterroso, Jennifer F Moore, Simon Musila, Sedjro Gilles A Nago, Maganizo W Namoto, Fatimata Niang, Violaine Nicolas, Jerry B Nkenku, Evans E Nkrumah, Gonwouo L Nono, Mulavwa M Norbert, Katarzyna Nowak, Benneth C Obitte, Arnold D Okoni-Williams, Jonathan Onongo, M Justin O'Riain, Samuel T Osinubi, Daniel M Parker, Francesca Parrini, Mike J S Peel, Johannes Penner, Darren W Pietersen, Andrew J Plumptre, Damian W Ponsonby, Stefan Porembski, R John Power, Frans G T Radloff, Ramugondo V Rambau, Tharmalingam Ramesh, Leigh R Richards, Mark-Oliver Rödel, Dominic P Rollinson, Francesco Rovero, Mostafa A Saleh, Ute Schmiedel, M Corrie Schoeman, Paul Scholte, Thomas L Serfass, Julie Teresa Shapiro, Sidney Shema, Stefan J Siebert, Jasper A Slingsby, Alexander Sliwa, Hanneline A Smit-Robinson, Etotepe A Sogbohossou, Michael J Somers, Stephen Spawls, Jarryd P Streicher, Lourens Swanepoel, Iroro Tanshi, Peter J Taylor, William A Taylor, Mariska Te Beest, Paul T Telfer, Dave I Thompson, Elie Tobi, Krystal A Tolley, Andrew A Turner, Wayne Twine, Victor Van Cakenberghe, Frederik Van de Perre, Helga van der Merwe, Chris J G van Niekerk, Pieter C V van Wyk, Jan A Venter, Luke Verburgt, Geraldine Veron, Susanne Vetter, Maria S Vorontsova, Thomas C Wagner, Paul W Webala, Natalie Weber, Sina M Weier, Paula A White, Melissa A Whitecross, Benjamin J Wigley, Frank J Willems, Christiaan W Winterbach, Galena M Woodhouse
Sub-Saharan Africa is under-represented in global biodiversity datasets, particularly regarding the impact of land use on species' population abundances. Drawing on recent advances in expert elicitation to ensure data consistency, 200 experts were convened using a modified-Delphi process to estimate 'intactness scores': the remaining proportion of an 'intact' reference population of a species group in a particular land use, on a scale from 0 (no remaining individuals) to 1 (same abundance as the reference) and, in rare cases, to 2 (populations that thrive in human-modified landscapes)...
February 12, 2024: Scientific Data
#2
JOURNAL ARTICLE
Declan L M Cooper, Simon L Lewis, Martin J P Sullivan, Paulo I Prado, Hans Ter Steege, Nicolas Barbier, Ferry Slik, Bonaventure Sonké, Corneille E N Ewango, Stephen Adu-Bredu, Kofi Affum-Baffoe, Daniel P P de Aguiar, Manuel Augusto Ahuite Reategui, Shin-Ichiro Aiba, Bianca Weiss Albuquerque, Francisca Dionízia de Almeida Matos, Alfonso Alonso, Christian A Amani, Dário Dantas do Amaral, Iêda Leão do Amaral, Ana Andrade, Ires Paula de Andrade Miranda, Ilondea B Angoboy, Alejandro Araujo-Murakami, Nicolás Castaño Arboleda, Luzmila Arroyo, Peter Ashton, Gerardo A Aymard C, Cláudia Baider, Timothy R Baker, Michael Philippe Bessike Balinga, Henrik Balslev, Lindsay F Banin, Olaf S Bánki, Chris Baraloto, Edelcilio Marques Barbosa, Flávia Rodrigues Barbosa, Jos Barlow, Jean-Francois Bastin, Hans Beeckman, Serge Begne, Natacha Nssi Bengone, Erika Berenguer, Nicholas Berry, Robert Bitariho, Pascal Boeckx, Jan Bogaert, Bernard Bonyoma, Patrick Boundja, Nils Bourland, Faustin Boyemba Bosela, Fabian Brambach, Roel Brienen, David F R P Burslem, José Luís Camargo, Wegliane Campelo, Angela Cano, Sasha Cárdenas, Dairon Cárdenas López, Rainiellen de Sá Carpanedo, Yrma Andreina Carrero Márquez, Fernanda Antunes Carvalho, Luisa Fernanda Casas, Hernán Castellanos, Carolina V Castilho, Carlos Cerón, Colin A Chapman, Jerome Chave, Phourin Chhang, Wanlop Chutipong, George B Chuyong, Bruno Barçante Ladvocat Cintra, Connie J Clark, Fernanda Coelho de Souza, James A Comiskey, David A Coomes, Fernando Cornejo Valverde, Diego F Correa, Flávia R C Costa, Janaina Barbosa Pedrosa Costa, Pierre Couteron, Heike Culmsee, Aida Cuni-Sanchez, Francisco Dallmeier, Gabriel Damasco, Gilles Dauby, Nállarett Dávila, Hilda Paulette Dávila Doza, Jose Don T De Alban, Rafael L de Assis, Charles De Canniere, Thales De Haulleville, Marcelo de Jesus Veiga Carim, Layon O Demarchi, Kyle G Dexter, Anthony Di Fiore, Hazimah Haji Mohammad Din, Mathias I Disney, Brice Yannick Djiofack, Marie-Noël K Djuikouo, Tran Van Do, Jean-Louis Doucet, Freddie C Draper, Vincent Droissart, Joost F Duivenvoorden, Julien Engel, Vittoria Estienne, William Farfan-Rios, Sophie Fauset, Kenneth J Feeley, Yuri Oliveira Feitosa, Ted R Feldpausch, Cid Ferreira, Joice Ferreira, Leandro Valle Ferreira, Christine D Fletcher, Bernardo Monteiro Flores, Alusine Fofanah, Ernest G Foli, Émile Fonty, Gabriella M Fredriksson, Alfredo Fuentes, David Galbraith, George Pepe Gallardo Gonzales, Karina Garcia-Cabrera, Roosevelt García-Villacorta, Vitor H F Gomes, Ricardo Zárate Gómez, Therany Gonzales, Rogerio Gribel, Marcelino Carneiro Guedes, Juan Ernesto Guevara, Khalid Rehman Hakeem, Jefferson S Hall, Keith C Hamer, Alan C Hamilton, David J Harris, Rhett D Harrison, Terese B Hart, Andy Hector, Terry W Henkel, John Herbohn, Mireille B N Hockemba, Bruce Hoffman, Milena Holmgren, Euridice N Honorio Coronado, Isau Huamantupa-Chuquimaco, Wannes Hubau, Nobuo Imai, Mariana Victória Irume, Patrick A Jansen, Kathryn J Jeffery, Eliana M Jimenez, Tommaso Jucker, André Braga Junqueira, Michelle Kalamandeen, Narcisse G Kamdem, Kuswata Kartawinata, Emmanuel Kasongo Yakusu, John M Katembo, Elizabeth Kearsley, David Kenfack, Michael Kessler, Thiri Toe Khaing, Timothy J Killeen, Kanehiro Kitayama, Bente Klitgaard, Nicolas Labrière, Yves Laumonier, Susan G W Laurance, William F Laurance, Félix Laurent, Tinh Cong Le, Trai Trong Le, Miguel E Leal, Evlyn Márcia Leão de Moraes Novo, Aurora Levesley, Moses B Libalah, Juan Carlos Licona, Diógenes de Andrade Lima Filho, Jeremy A Lindsell, Aline Lopes, Maria Aparecida Lopes, Jon C Lovett, Richard Lowe, José Rafael Lozada, Xinghui Lu, Nestor K Luambua, Bruno Garcia Luize, Paul Maas, José Leonardo Lima Magalhães, William E Magnusson, Ni Putu Diana Mahayani, Jean-Remy Makana, Yadvinder Malhi, Lorena Maniguaje Rincón, Asyraf Mansor, Angelo Gilberto Manzatto, Beatriz S Marimon, Ben Hur Marimon-Junior, Andrew R Marshall, Maria Pires Martins, Faustin M Mbayu, Marcelo Brilhante de Medeiros, Italo Mesones, Faizah Metali, Vianet Mihindou, Jerome Millet, William Milliken, Hugo F Mogollón, Jean-François Molino, Mohd Nizam Mohd Said, Abel Monteagudo Mendoza, Juan Carlos Montero, Sam Moore, Bonifacio Mostacedo, Linder Felipe Mozombite Pinto, Sharif Ahmed Mukul, Pantaleo K T Munishi, Hidetoshi Nagamasu, Henrique Eduardo Mendonça Nascimento, Marcelo Trindade Nascimento, David Neill, Reuben Nilus, Janaína Costa Noronha, Laurent Nsenga, Percy Núñez Vargas, Lucas Ojo, Alexandre A Oliveira, Edmar Almeida de Oliveira, Fidèle Evouna Ondo, Walter Palacios Cuenca, Susamar Pansini, Marcelo Petratti Pansonato, Marcos Ríos Paredes, Ekananda Paudel, Daniela Pauletto, Richard G Pearson, José Luis Marcelo Pena, R Toby Pennington, Carlos A Peres, Andrea Permana, Pascal Petronelli, Maria Cristina Peñuela Mora, Juan Fernando Phillips, Oliver L Phillips, Georgia Pickavance, Maria Teresa Fernandez Piedade, Nigel C A Pitman, Pierre Ploton, Andreas Popelier, John R Poulsen, Adriana Prieto, Richard B Primack, Hari Priyadi, Lan Qie, Adriano Costa Quaresma, Helder Lima de Queiroz, Hirma Ramirez-Angulo, José Ferreira Ramos, Neidiane Farias Costa Reis, Jan Reitsma, Juan David Cardenas Revilla, Terhi Riutta, Gonzalo Rivas-Torres, Iyan Robiansyah, Maira Rocha, Domingos de Jesus Rodrigues, M Elizabeth Rodriguez-Ronderos, Francesco Rovero, Andes H Rozak, Agustín Rudas, Ervan Rutishauser, Daniel Sabatier, Le Bienfaiteur Sagang, Adeilza Felipe Sampaio, Ismayadi Samsoedin, Manichanh Satdichanh, Juliana Schietti, Jochen Schöngart, Veridiana Vizoni Scudeller, Naret Seuaturien, Douglas Sheil, Rodrigo Sierra, Miles R Silman, Thiago Sanna Freire Silva, José Renan da Silva Guimarães, Murielle Simo-Droissart, Marcelo Fragomeni Simon, Plinio Sist, Thaiane R Sousa, Emanuelle de Sousa Farias, Luiz de Souza Coelho, Dominick V Spracklen, Suzanne M Stas, Robert Steinmetz, Pablo R Stevenson, Juliana Stropp, Rahayu S Sukri, Terry C H Sunderland, Eizi Suzuki, Michael D Swaine, Jianwei Tang, James Taplin, David M Taylor, J Sebastián Tello, John Terborgh, Nicolas Texier, Ida Theilade, Duncan W Thomas, Raquel Thomas, Sean C Thomas, Milton Tirado, Benjamin Toirambe, José Julio de Toledo, Kyle W Tomlinson, Armando Torres-Lezama, Hieu Dang Tran, John Tshibamba Mukendi, Roven D Tumaneng, Maria Natalia Umaña, Peter M Umunay, Ligia Estela Urrego Giraldo, Elvis H Valderrama Sandoval, Luis Valenzuela Gamarra, Tinde R Van Andel, Martin van de Bult, Jaqueline van de Pol, Geertje van der Heijden, Rodolfo Vasquez, César I A Vela, Eduardo Martins Venticinque, Hans Verbeeck, Rizza Karen A Veridiano, Alberto Vicentini, Ima Célia Guimarães Vieira, Emilio Vilanova Torre, Daniel Villarroel, Boris Eduardo Villa Zegarra, Jason Vleminckx, Patricio von Hildebrand, Vincent Antoine Vos, Corine Vriesendorp, Edward L Webb, Lee J T White, Serge Wich, Florian Wittmann, Roderick Zagt, Runguo Zang, Charles Eugene Zartman, Lise Zemagho, Egleé L Zent, Stanford Zent
Trees structure the Earth's most biodiverse ecosystem, tropical forests. The vast number of tree species presents a formidable challenge to understanding these forests, including their response to environmental change, as very little is known about most tropical tree species. A focus on the common species may circumvent this challenge. Here we investigate abundance patterns of common tree species using inventory data on 1,003,805 trees with trunk diameters of at least 10 cm across 1,568 locations1-6 in closed-canopy, structurally intact old-growth tropical forests in Africa, Amazonia and Southeast Asia...
January 10, 2024: Nature
#3
REVIEW
Maximilian Stahl, Jan Philipp Bewersdorf, Zhuoer Xie, Matteo Giovanni Della Porta, Rami Komrokji, Mina L Xu, Omar Abdel-Wahab, Justin Taylor, David P Steensma, Daniel T Starczynowski, Mikkael A Sekeres, Guillermo Sanz, David A Sallman, Gail J Roboz, Uwe Platzbecker, Mrinal M Patnaik, Eric Padron, Olatoyosi Odenike, Stephen D Nimer, Aziz Nazha, Ravi Majeti, Sanam Loghavi, Richard F Little, Alan F List, Tae Kon Kim, Christopher S Hourigan, Robert P Hasserjian, Stephanie Halene, Elizabeth A Griffiths, Steven D Gore, Peter Greenberg, Maria E Figueroa, Pierre Fenaux, Fabio Efficace, Amy E DeZern, Naval G Daver, Jane E Churpek, Hetty E Carraway, Rena Buckstein, Andrew M Brunner, Jacqueline Boultwood, Uma Borate, Rafael Bejar, John M Bennett, Andrew H Wei, Valeria Santini, Michael R Savona, Amer M Zeidan
The guidelines for classification, prognostication, and response assessment of myelodysplastic syndromes/neoplasms (MDS) have all recently been updated. In this report on behalf of the International Consortium for MDS (icMDS) we summarize these developments. We first critically examine the updated World Health Organization (WHO) classification and the International Consensus Classification (ICC) of MDS. We then compare traditional and molecularly based risk MDS risk assessment tools. Lastly, we discuss limitations of criteria in measuring therapeutic benefit and highlight how the International Working Group (IWG) 2018 and 2023 response criteria addressed these deficiencies and are endorsed by the icMDS...
November 2023: Blood Reviews
#4
JOURNAL ARTICLE
Claude Bragard, Paula Baptista, Elisavet Chatzivassiliou, Francesco Di Serio, Paolo Gonthier, Josep Anton Jaques Miret, Annemarie Fejer Justesen, Alan MacLeod, Christer Sven Magnusson, Panagiotis Milonas, Juan A Navas-Cortes, Stephen Parnell, Roel Potting, Emilio Stefani, Hans-Hermann Thulke, Wopke Van der Werf, Antonio Vicent Civera, Jonathan Yuen, Lucia Zappalà, Quirico Migheli, Irene Vloutoglou, Andrea Maiorano, Marco Pautasso, Philippe Lucien Reignault
The EFSA Plant Health Panel performed a pest categorisation of Coleosporium asterum (Dietel) Sydow & P. Sydow, Coleosporium montanum (Arthur & F. Kern) and Coleosporium solidaginis (Schwein.) Thüm, three basidiomycete fungi belonging to the family Coleosporiaceae, causing rust diseases on Pinus spp. (aecial hosts) and on Asteraceae (telial hosts). Coleosporium asterum was described on Aster spp. in Japan and has been reported from China, Korea, France and Portugal. Coleosporium montanum is native to North America, has been introduced to Asia and has been reported from Austria on Symphyotrichum spp...
June 2023: EFSA journal
#5
JOURNAL ARTICLE
Michelle B Riba, Kristine A Donovan, Kauser Ahmed, Barbara Andersen, IIana Braun, William S Breitbart, Benjamin W Brewer, Cheyenne Corbett, Jesse Fann, Stewart Fleishman, Sofia Garcia, Donna B Greenberg, George F Handzo, Laura Herald Hoofring, Chao-Hui Huang, Sean Hutchinson, Shelley Johns, Jennifer Keller, Pallavi Kumar, Sheila Lahijani, Sara Martin, Shehzad K Niazi, Megan Pailler, Francine Parnes, Vinay Rao, Jaroslava Salman, Eli Scher, Jessica Schuster, Melissa Teply, Angela Usher, Alan D Valentine, Jessica Vanderlan, Megan S Lyons, Nicole R McMillian, Susan D Darlow
These NCCN Guidelines for Distress Management discuss the identification and treatment of psychosocial problems in patients with cancer. All patients experience some level of distress associated with a cancer diagnosis and the effects of the disease and its treatment regardless of the stage of disease. Clinically significant levels of distress occur in a subset of patients, and identification and treatment of distress are of utmost importance. The NCCN Distress Management Panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations...
May 2023: Journal of the National Comprehensive Cancer Network: JNCCN
#6
REVIEW
Jan Philipp Bewersdorf, Zhuoer Xie, Rafael Bejar, Uma Borate, Jacqueline Boultwood, Andrew M Brunner, Rena Buckstein, Hetty E Carraway, Jane E Churpek, Naval G Daver, Matteo Giovanni Della Porta, Amy E DeZern, Pierre Fenaux, Maria E Figueroa, Steven D Gore, Elizabeth A Griffiths, Stephanie Halene, Robert P Hasserjian, Christopher S Hourigan, Tae Kon Kim, Rami Komrokji, Vijay K Kuchroo, Alan F List, Sanam Loghavi, Ravindra Majeti, Olatoyosi Odenike, Mrinal M Patnaik, Uwe Platzbecker, Gail J Roboz, David A Sallman, Valeria Santini, Guillermo Sanz, Mikkael A Sekeres, Maximilian Stahl, Daniel T Starczynowski, David P Steensma, Justin Taylor, Omar Abdel-Wahab, Mina L Xu, Michael R Savona, Andrew H Wei, Amer M Zeidan
Biological events that contribute to the pathogenesis of myelodysplastic syndromes/neoplasms (MDS) are becoming increasingly characterized and are being translated into rationally designed therapeutic strategies. Herein, we provide updates from the first International Workshop on MDS (iwMDS) of the International Consortium for MDS (icMDS) detailing recent advances in understanding the genetic landscape of MDS, including germline predisposition, epigenetic and immune dysregulation, the complexities of clonal hematopoiesis progression to MDS, as well as novel animal models of the disease...
July 2023: Blood Reviews
#7
JOURNAL ARTICLE
Grace A Ward, Robert P Dalton, Benjamin S Meyer, Amy F McLemore, Amy L Aldrich, Nghi B Lam, Alexis H Onimus, Nicole D Vincelette, Thu Le Trinh, Xianghong Chen, Alexandra R Calescibetta, Sean M Christiansen, Hsin-An Hou, Joseph O Johnson, Kenneth L Wright, Eric Padron, Erika A Eksioglu, Alan F List
Myelodysplastic Syndromes (MDSs) are bone marrow (BM) failure malignancies characterized by constitutive innate immune activation, including NLRP3 inflammasome driven pyroptotic cell death. We recently reported that the danger-associated molecular pattern (DAMP) oxidized mitochondrial DNA (ox-mtDNA) is diagnostically increased in MDS plasma although the functional consequences remain poorly defined. We hypothesized that ox-mtDNA is released into the cytosol, upon NLRP3 inflammasome pyroptotic lysis, where it propagates and further enhances the inflammatory cell death feed-forward loop onto healthy tissues...
February 15, 2023: International Journal of Molecular Sciences
#8
REVIEW
Zhixu Ni, Michele Wölk, Geoff Jukes, Karla Mendivelso Espinosa, Robert Ahrends, Lucila Aimo, Jorge Alvarez-Jarreta, Simon Andrews, Robert Andrews, Alan Bridge, Geremy C Clair, Matthew J Conroy, Eoin Fahy, Caroline Gaud, Laura Goracci, Jürgen Hartler, Nils Hoffmann, Dominik Kopczyinki, Ansgar Korf, Andrea F Lopez-Clavijo, Adnan Malik, Jacobo Miranda Ackerman, Martijn R Molenaar, Claire O'Donovan, Tomáš Pluskal, Andrej Shevchenko, Denise Slenter, Gary Siuzdak, Martina Kutmon, Hiroshi Tsugawa, Egon L Willighagen, Jianguo Xia, Valerie B O'Donnell, Maria Fedorova
Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across biology and biomedicine. These generate extremely large raw datasets requiring sophisticated solutions to support automated data processing. To address this, numerous software tools have been developed and tailored for specific tasks. However, for researchers, deciding which approach best suits their application relies on ad hoc testing, which is inefficient and time consuming. Here we first review the data processing pipeline, summarizing the scope of available tools...
December 21, 2022: Nature Methods
#9
REVIEW
John Mascarenhas, Hélène F E Gleitz, Helen T Chifotides, Claire N Harrison, Srdan Verstovsek, Alessandro Maria Vannucchi, Raajit K Rampal, Jean-Jacques Kiladjian, William Vainchenker, Ronald Hoffman, Rebekka K Schneider, Alan F List
Myelofibrosis (MF) is a myeloproliferative disorder that exhibits considerable biological and clinical heterogeneity. At the two ends of the disease spectrum are the myelodepletive or cytopenic phenotype and the myeloproliferative phenotype. The cytopenic phenotype has a high prevalence in primary MF (PMF) and is characterized by low blood counts. The myeloproliferative phenotype is typically associated with secondary MF (SMF), mild anemia, minimal need for transfusion support, and normal to mild thrombocytopenia...
February 2023: Leukemia
#10
JOURNAL ARTICLE
Maximilian Stahl, Omar Abdel-Wahab, Andrew H Wei, Michael R Savona, Mina L Xu, Zhuoer Xie, Justin Taylor, Daniel T Starczynowski, Guillermo F Sanz, David A Sallman, Valeria Santini, Gail J Roboz, Mrinal M Patnaik, Eric Padron, Olatoyosi Odenike, Aziz Nazha, Stephen D Nimer, Ravindra Majeti, Richard F Little, Steven D Gore, Alan F List, Vijay Kuchroo, Rami S Komrokji, Tae Kon Kim, Nina Kim, Christopher S Hourigan, Robert P Hasserjian, Stephanie Halene, Elizabeth A Griffiths, Peter L Greenberg, Maria E Figueroa, Pierre Fenaux, Fabio Efficace, Amy E DeZern, Matteo G Della Porta, Naval G Daver, Jane E Churpek, Hetty E Carraway, Andrew M Brunner, Uma Borate, John M Bennett, Rafael Bejar, Jacqueline Boultwood, Sanam Loghavi, Jan Philipp Bewersdorf, Uwe Platzbecker, David P Steensma, Mikkael A Sekeres, Rena J Buckstein, Amer M Zeidan
No abstract text is available yet for this article.
October 19, 2022: Blood Advances
#11
JOURNAL ARTICLE
Amy N Costa, Ashley F Curtis, Madison Musich, Alan A Guandique, Christina S McCrae
Poor subjective evaluation of cognition and sleep are associated with cognitive decline in older adults. Relationships among self-reported cognition, sleep, and cognitive domains remain unclear. We evaluated the interactive associations of objective cognition and subjective sleep with self-reported cognition in older adults with insomnia. Fifty-one older adults (Mage = 69.19, SD = 7.95) with insomnia completed 14 days of self-reported cognition ratings (0-very poor, 100-very good), sleep (total sleep time (TST), sleep onset latency (SOL), wake after sleep onset (WASO), sleep efficiency), and daily cognitive tasks: Letter series (reasoning), word list delayed recall (verbal memory), Symbol Digit Modalities Test (SDMT) (attention/processing speed), and number copy (processing speed)...
October 11, 2022: Journal of Sleep Research
#12
JOURNAL ARTICLE
Karthik Thangappan, Farhan Zafar, Hosam F Ahmed, Jason W Greenberg, Awais Ashfaq, Russel Hirsch, Clifford Chin, David Lehenbauer, Alan O'Donnell, David L S Morales
OBJECTIVE: The purpose of this study was to assess post-transplantation outcomes in recipients with increased pulmonary vascular resistance (PVR) in relation to donor size. METHODS: The United Network for Organ Sharing database was used to identify patients ages 0 to 18 years at time of listing who underwent transplantation from 2010 to 2019 and for whom cardiac catheterization and donor-recipient weight ratio data were available. Patients were divided according to listing PVR into <3, 3 to 6, and >6 Wood units...
May 10, 2022: Journal of Thoracic and Cardiovascular Surgery
#13
JOURNAL ARTICLE
Shweta Ramdas, Jonathan Judd, Sarah E Graham, Stavroula Kanoni, Yuxuan Wang, Ida Surakka, Brandon Wenz, Shoa L Clarke, Alessandra Chesi, Andrew Wells, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W Winkler, Adam E Locke, Eirini Marouli, Greg J M Zajac, Kuan-Han H Wu, Ioanna Ntalla, Qin Hui, Derek Klarin, Austin T Hilliard, Zeyuan Wang, Chao Xue, Gudmar Thorleifsson, Anna Helgadottir, Daniel F Gudbjartsson, Hilma Holm, Isleifur Olafsson, Mi Yeong Hwang, Sohee Han, Masato Akiyama, Saori Sakaue, Chikashi Terao, Masahiro Kanai, Wei Zhou, Ben M Brumpton, Humaira Rasheed, Aki S Havulinna, Yogasudha Veturi, Jennifer Allen Pacheco, Elisabeth A Rosenthal, Todd Lingren, QiPing Feng, Iftikhar J Kullo, Akira Narita, Jun Takayama, Hilary C Martin, Karen A Hunt, Bhavi Trivedi, Jeffrey Haessler, Franco Giulianini, Yuki Bradford, Jason E Miller, Archie Campbell, Kuang Lin, Iona Y Millwood, Asif Rasheed, George Hindy, Jessica D Faul, Wei Zhao, David R Weir, Constance Turman, Hongyan Huang, Mariaelisa Graff, Ananyo Choudhury, Dhriti Sengupta, Anubha Mahajan, Michael R Brown, Weihua Zhang, Ketian Yu, Ellen M Schmidt, Anita Pandit, Stefan Gustafsson, Xianyong Yin, Jian'an Luan, Jing-Hua Zhao, Fumihiko Matsuda, Hye-Mi Jang, Kyungheon Yoon, Carolina Medina-Gomez, Achilleas Pitsillides, Jouke Jan Hottenga, Andrew R Wood, Yingji Ji, Zishan Gao, Simon Haworth, Ruth E Mitchell, Jin Fang Chai, Mette Aadahl, Anne A Bjerregaard, Jie Yao, Ani Manichaikul, Wen-Jane Lee, Chao Agnes Hsiung, Helen R Warren, Julia Ramirez, Jette Bork-Jensen, Line L Kårhus, Anuj Goel, Maria Sabater-Lleal, Raymond Noordam, Pala Mauro, Floris Matteo, Aaron F McDaid, Pedro Marques-Vidal, Matthias Wielscher, Stella Trompet, Naveed Sattar, Line T Møllehave, Matthias Munz, Lingyao Zeng, Jianfeng Huang, Bin Yang, Alaitz Poveda, Azra Kurbasic, Sebastian Schönherr, Lukas Forer, Markus Scholz, Tessel E Galesloot, Jonathan P Bradfield, Sanni E Ruotsalainen, E Warwick Daw, Joseph M Zmuda, Jonathan S Mitchell, Christian Fuchsberger, Henry Christensen, Jennifer A Brody, Phuong Le, Mary F Feitosa, Mary K Wojczynski, Daiane Hemerich, Michael Preuss, Massimo Mangino, Paraskevi Christofidou, Niek Verweij, Jan W Benjamins, Jorgen Engmann, Tsao L Noah, Anurag Verma, Roderick C Slieker, Ken Sin Lo, Nuno R Zilhao, Marcus E Kleber, Graciela E Delgado, Shaofeng Huo, Daisuke D Ikeda, Hiroyuki Iha, Jian Yang, Jun Liu, Ayşe Demirkan, Hampton L Leonard, Jonathan Marten, Carina Emmel, Börge Schmidt, Laura J Smyth, Marisa Cañadas-Garre, Chaolong Wang, Masahiro Nakatochi, Andrew Wong, Nina Hutri-Kähönen, Xueling Sim, Rui Xia, Alicia Huerta-Chagoya, Juan Carlos Fernandez-Lopez, Valeriya Lyssenko, Suraj S Nongmaithem, Alagu Sankareswaran, Marguerite R Irvin, Christopher Oldmeadow, Han-Na Kim, Seungho Ryu, Paul R H J Timmers, Liubov Arbeeva, Rajkumar Dorajoo, Leslie A Lange, Gauri Prasad, Laura Lorés-Motta, Marc Pauper, Jirong Long, Xiaohui Li, Elizabeth Theusch, Fumihiko Takeuchi, Cassandra N Spracklen, Anu Loukola, Sailalitha Bollepalli, Sophie C Warner, Ya Xing Wang, Wen B Wei, Teresa Nutile, Daniela Ruggiero, Yun Ju Sung, Shufeng Chen, Fangchao Liu, Jingyun Yang, Katherine A Kentistou, Bernhard Banas, Anna Morgan, Karina Meidtner, Lawrence F Bielak, Jennifer A Smith, Prashantha Hebbar, Aliki-Eleni Farmaki, Edith Hofer, Maoxuan Lin, Maria Pina Concas, Simona Vaccargiu, Peter J van der Most, Niina Pitkänen, Brian E Cade, Sander W van der Laan, Kumaraswamy Naidu Chitrala, Stefan Weiss, Amy R Bentley, Ayo P Doumatey, Adebowale A Adeyemo, Jong Young Lee, Eva R B Petersen, Aneta A Nielsen, Hyeok Sun Choi, Maria Nethander, Sandra Freitag-Wolf, Lorraine Southam, Nigel W Rayner, Carol A Wang, Shih-Yi Lin, Jun-Sing Wang, Christian Couture, Leo-Pekka Lyytikäinen, Kjell Nikus, Gabriel Cuellar-Partida, Henrik Vestergaard, Bertha Hidalgo, Olga Giannakopoulou, Qiuyin Cai, Morgan O Obura, Jessica van Setten, Karen Y He, Hua Tang, Natalie Terzikhan, Jae Hun Shin, Rebecca D Jackson, Alexander P Reiner, Lisa Warsinger Martin, Zhengming Chen, Liming Li, Takahisa Kawaguchi, Joachim Thiery, Joshua C Bis, Lenore J Launer, Huaixing Li, Mike A Nalls, Olli T Raitakari, Sahoko Ichihara, Sarah H Wild, Christopher P Nelson, Harry Campbell, Susanne Jäger, Toru Nabika, Fahd Al-Mulla, Harri Niinikoski, Peter S Braund, Ivana Kolcic, Peter Kovacs, Tota Giardoglou, Tomohiro Katsuya, Dominique de Kleijn, Gert J de Borst, Eung Kweon Kim, Hieab H H Adams, M Arfan Ikram, Xiaofeng Zhu, Folkert W Asselbergs, Adriaan O Kraaijeveld, Joline W J Beulens, Xiao-Ou Shu, Loukianos S Rallidis, Oluf Pedersen, Torben Hansen, Paul Mitchell, Alex W Hewitt, Mika Kähönen, Louis Pérusse, Claude Bouchard, Anke Tönjes, Yii-Der Ida Chen, Craig E Pennell, Trevor A Mori, Wolfgang Lieb, Andre Franke, Claes Ohlsson, Dan Mellström, Yoon Shin Cho, Hyejin Lee, Jian-Min Yuan, Woon-Puay Koh, Sang Youl Rhee, Jeong-Taek Woo, Iris M Heid, Klaus J Stark, Martina E Zimmermann, Henry Völzke, Georg Homuth, Michele K Evans, Alan B Zonderman, Ozren Polasek, Gerard Pasterkamp, Imo E Hoefer, Susan Redline, Katja Pahkala, Albertine J Oldehinkel, Harold Snieder, Ginevra Biino, Reinhold Schmidt, Helena Schmidt, Stefania Bandinelli, George Dedoussis, Thangavel Alphonse Thanaraj, Patricia A Peyser, Norihiro Kato, Matthias B Schulze, Giorgia Girotto, Carsten A Böger, Bettina Jung, Peter K Joshi, David A Bennett, Philip L De Jager, Xiangfeng Lu, Vasiliki Mamakou, Morris Brown, Mark J Caulfield, Patricia B Munroe, Xiuqing Guo, Marina Ciullo, Jost B Jonas, Nilesh J Samani, Jaakko Kaprio, Päivi Pajukanta, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Linda S Adair, Sonny Augustin Bechayda, H Janaka de Silva, Ananda R Wickremasinghe, Ronald M Krauss, Jer-Yuarn Wu, Wei Zheng, Anneke I den Hollander, Dwaipayan Bharadwaj, Adolfo Correa, James G Wilson, Lars Lind, Chew-Kiat Heng, Amanda E Nelson, Yvonne M Golightly, James F Wilson, Brenda Penninx, Hyung-Lae Kim, John Attia, Rodney J Scott, D C Rao, Donna K Arnett, Mark Walker, Laura J Scott, Heikki A Koistinen, Giriraj R Chandak, Josep M Mercader, Clicerio Gonzalez Villalpando, Lorena Orozco, Myriam Fornage, E Shyong Tai, Rob M van Dam, Terho Lehtimäki, Nish Chaturvedi, Mitsuhiro Yokota, Jianjun Liu, Dermot F Reilly, Amy Jayne McKnight, Frank Kee, Karl-Heinz Jöckel, Mark I McCarthy, Colin N A Palmer, Veronique Vitart, Caroline Hayward, Eleanor Simonsick, Cornelia M van Duijn, Zi-Bing Jin, Fan Lu, Haretsugu Hishigaki, Xu Lin, Winfried März, Vilmundur Gudnason, Jean-Claude Tardif, Guillaume Lettre, Leen M T Hart, Petra J M Elders, Daniel J Rader, Scott M Damrauer, Meena Kumari, Mika Kivimaki, Pim van der Harst, Tim D Spector, Ruth J F Loos, Michael A Province, Esteban J Parra, Miguel Cruz, Bruce M Psaty, Ivan Brandslund, Peter P Pramstaller, Charles N Rotimi, Kaare Christensen, Samuli Ripatti, Elisabeth Widén, Hakon Hakonarson, Struan F A Grant, Lambertus Kiemeney, Jacqueline de Graaf, Markus Loeffler, Florian Kronenberg, Dongfeng Gu, Jeanette Erdmann, Heribert Schunkert, Paul W Franks, Allan Linneberg, J Wouter Jukema, Amit V Khera, Minna Männikkö, Marjo-Riitta Jarvelin, Zoltan Kutalik, Cucca Francesco, Dennis O Mook-Kanamori, Ko Willems van Dijk, Hugh Watkins, David P Strachan, Niels Grarup, Peter Sever, Neil Poulter, Wayne Huey-Herng Sheu, Jerome I Rotter, Thomas M Dantoft, Fredrik Karpe, Matt J Neville, Nicholas J Timpson, Ching-Yu Cheng, Tien-Yin Wong, Chiea Chuen Khor, Hengtong Li, Charumathi Sabanayagam, Annette Peters, Christian Gieger, Andrew T Hattersley, Nancy L Pedersen, Patrik K E Magnusson, Dorret I Boomsma, Eco J C de Geus, L Adrienne Cupples, Joyce B J van Meurs, Arfan Ikram, Mohsen Ghanbari, Penny Gordon-Larsen, Wei Huang, Young Jin Kim, Yasuharu Tabara, Nicholas J Wareham, Claudia Langenberg, Eleftheria Zeggini, Jaakko Tuomilehto, Johanna Kuusisto, Markku Laakso, Erik Ingelsson, Goncalo Abecasis, John C Chambers, Jaspal S Kooner, Paul S de Vries, Alanna C Morrison, Scott Hazelhurst, Michèle Ramsay, Kari E North, Martha Daviglus, Peter Kraft, Nicholas G Martin, John B Whitfield, Shahid Abbas, Danish Saleheen, Robin G Walters, Michael V Holmes, Corri Black, Blair H Smith, Aris Baras, Anne E Justice, Julie E Buring, Paul M Ridker, Daniel I Chasman, Charles Kooperberg, Gen Tamiya, Masayuki Yamamoto, David A van Heel, Richard C Trembath, Wei-Qi Wei, Gail P Jarvik, Bahram Namjou, M Geoffrey Hayes, Marylyn D Ritchie, Pekka Jousilahti, Veikko Salomaa, Kristian Hveem, Bjørn Olav Åsvold, Michiaki Kubo, Yoichiro Kamatani, Yukinori Okada, Yoshinori Murakami, Bong-Jo Kim, Unnur Thorsteinsdottir, Kari Stefansson, Jifeng Zhang, Y Eugene Chen, Yuk-Lam Ho, Julie A Lynch, Philip S Tsao, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, John M Gaziano, Peter Wilson, Karen L Mohlke, Timothy M Frayling, Joel N Hirschhorn, Sekar Kathiresan, Michael Boehnke, Struan Grant, Pradeep Natarajan, Yan V Sun, Andrew P Morris, Panos Deloukas, Gina Peloso, Themistocles L Assimes, Cristen J Willer, Xiang Zhu, Christopher D Brown
A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We first prioritize lipid-associated genes with expression quantitative trait locus (eQTL) colocalizations and then add chromatin interaction data to narrow the search for functional genes...
August 4, 2022: American Journal of Human Genetics
#14
REVIEW
Jeremy Hill, Toby Ashken, Simeon West, Alan James Robert Macfarlane, Kariem El-Boghdadly, Eric Albrecht, Ki Jinn Chin, Ben Fox, Ashwani Gupta, Stephen Haskins, Nat Haslam, Rosemary Margaret Gilmore Hogg, Anil Hormis, David F Johnston, Edward R Mariano, Peter Merjavy, Timothy Moll, James Parry, Amit Pawa, Kim Russon, Maria Paz Sebastian, Lloyd Turbitt, Jonathan Womack, Maria Chazapis
BACKGROUND/IMPORTANCE: There is heterogeneity among the outcomes used in regional anesthesia research. OBJECTIVE: We aimed to produce a core outcome set for regional anesthesia research. METHODS: We conducted a systematic review and Delphi study to develop this core outcome set. A systematic review of the literature from January 2015 to December 2019 was undertaken to generate a long list of potential outcomes to be included in the core outcome set...
July 21, 2022: Regional Anesthesia and Pain Medicine
#15
JOURNAL ARTICLE
Amy F McLemore, Hsin-An Hou, Benjamin S Meyer, Nghi B Lam, Grace A Ward, Amy L Aldrich, Matthew A Rodrigues, Alexis Vedder, Ling Zhang, Eric Padron, Nicole D Vincelette, David A Sallman, Omar Abdel-Wahab, Alan F List, Kathy L McGraw
NLRP3 inflammasome and interferon stimulated gene (ISG) induction are key biological drivers of ineffective hematopoiesis and inflammation in Myelodysplastic Syndromes (MDS). Gene mutations involving messenger RNA splicing and epigenetic regulatory pathways induce inflammasome activation and myeloid lineage skewing in MDS through yet undefined mechanisms. Using immortalized murine hematopoietic stem and progenitor cells harboring these somatic gene mutations and primary MDS bone marrow specimens, we show accumulation of unresolved R-loops and micronuclei with concurrent activation of the cytosolic sensor, cGAS...
July 5, 2022: JCI Insight
#16
JOURNAL ARTICLE
Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z Grice, Xing Fan, Byung-Chul Lee, Aisha A AlJanahi, So Gun Hong, Kelli L Vaughan, Julie A Mattison, Steven G Kohama, Margarete Alice Fabre, Naoya Uchida, Selami Demirci, Marcus A F Corat, Jean-Yves Métais, Katherine R Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L McGraw, Alan F List, Lambert Busque, John F Tisdale, George S Vassiliou, Kyung-Rok Yu, Cynthia E Dunbar
Individuals with age-related clonal hematopoiesis (CH) are at greater risk for hematologic malignancies and cardiovascular diseases. However, predictive preclinical animal models to recapitulate the spectrum of human CH are lacking. Through error-corrected sequencing of 56 human CH/myeloid malignancy genes we identified natural CH driver mutations in aged rhesus macaques matching genes somatically mutated in human CH, with DNMT3A mutations being the most frequent. A CH model in young adult macaques was generated via autologous transplantation of CRISPR/Cas9-mediated gene-edited hematopoietic stem and progenitor cells (HSPCs), targeting the top human CH genes with loss-of-function (LOF) mutations...
June 17, 2022: Blood
#17
JOURNAL ARTICLE
David A Sallman, Rafael Bejar, Guillermo Montalban-Bravo, Sandra E Kurtin, Alan F List, Guillermo Garcia-Manero, Stephen D Nimer, Casey L O'Connell, Dale Schaar, Janice Butchko, Tracey Iraca, Stephanie Searle
Objectives: Patient education resources that address barriers to health literacy to improve understanding and outcomes in myelodysplastic syndromes (MDS) are limited. The aim of this study was to evaluate the impact and outcomes benefits of An Animated Patient's Guide to Myelodysplastic Syndromes (MDS) cancer educational modules (which includes the 'You and MDS' website and YouTube hosted resources) related to MDS education, awareness, understanding and health outcomes. Methods: This was a retrospective study of learner feedback, metrics, and utilization data from July 2018 to August 2021...
2022: Leukemia Research Reports
#18
JOURNAL ARTICLE
Paulo Ventura, Helen Tse, José C Guerreiro, João Delgado, Miguel F Ferreira, António Farinha-Fernandes, Bruno Faustino, Alexandre Banha, Alan C-N Wong
Recently, paradigms in the face recognition literature have been adopted to reveal holistic processing in word recognition. It is unknown, however, whether different measures of holistic word processing share similar underlying mechanisms, and whether fluent word reading relies on holistic word processing. We measured holistic processing effects in three paradigms (composite, configural sensitivity, part-whole) as well as in reading fluency (3DM task: reading aloud high- and low-frequency words and pseudowords)...
May 12, 2022: Attention, Perception & Psychophysics
#19
JOURNAL ARTICLE
Daniel I Schlessinger, Kelly A Reynolds, McKenzie A Dirr, Sarah A Ibrahim, Arianna F Yanes, Jake M Lazaroff, Victoria Godinez-Puig, Brian R Chen, Anastasia O Kurta, Jill K Cotseones, Sarah G Chiren, Karina C Furlan, Sanjana Iyengar, Ramona Behshad, Danielle M DeHoratius, Pablo Denes, Aaron M Drucker, Leonard M Dzubow, Jeremy R Etzkorn, Catherine A Harwood, John Y S Kim, Naomi Lawrence, Erica H Lee, Gary S Lissner, Ashfaq A Marghoob, Rubeta N Matin, Adam R Mattox, Bharat B Mittal, J Regan Thomas, Xiaolong Alan Zhou, David Zloty, Jochen Schmitt, Jamie J Kirkham, April W Armstrong, Nicole Basset-Seguin, Elizabeth M Billingsley, Jeremy S Bordeaux, Jerry Brewer, Marc Brown, Mariah Brown, Scott A B Collins, Maria Concetta Fargnoli, Sergio Jobim De Azevedo, Reinhard Dummer, Alexander Eggermont, Glenn D Goldman, Merete Haedersdal, Elizabeth K Hale, Allison Hanlon, Kelly L Harms, Conway C Huang, Eva A Hurst, Gino K In, Nicole Kelleners-Smeets, Meenal Kheterpal, Barry Leshin, Michel Mcdonald, Stanley J Miller, Alexander Miller, Eliot N Mostow, Myrto Trakatelli, Kishwer S Nehal, Desiree Ratner, Howard Rogers, Kavita Y Sarin, Seaver L Soon, Thomas Stasko, Paul A Storrs, Luca Tagliaferri, Allison T Vidimos, Sandra L Wong, Siegrid S Yu, Iris Zalaudek, Nathalie C Zeitouni, John A Zitelli, Emily Poon, Joseph F Sobanko, Todd V Cartee, Ian A Maher, Murad Alam
BACKGROUND: There is variation in the outcomes reported in clinical studies of basal cell carcinoma. This can prevent effective meta-analyses from answering important clinical questions. OBJECTIVE: To identify a recommended minimum set of core outcomes for basal cell carcinoma clinical trials. METHODS: Patient and professional Delphi process to cull a long list, culminating in a consensus meeting. To be provisionally accepted, outcomes needed to be deemed important (score, 7-9, with 9 being the maximum) by 70% of each stakeholder group...
September 2022: Journal of the American Academy of Dermatology
#20
JOURNAL ARTICLE
Matthew G Spangler-Bickell, Samuel A Hurley, Ali Pirasteh, Scott B Perlman, Timothy W Deller, Alan B McMillan
Head motion during brain PET imaging can cause significant degradation of the quality of the reconstructed image, leading to reduced diagnostic value and inaccurate quantitation. A fully data-driven motion correction approach was recently demonstrated to produce highly accurate motion estimates (< 1 mm) with high temporal resolution (≥ 1 Hz), which can then be used for a motion corrected reconstruction. This can be applied retrospectively with no impact on the clinical image acquisition protocol. We present a reader-based evaluation and an atlas-based quantitative analysis of this motion correction approach within a clinical cohort...
January 27, 2022: Journal of Nuclear Medicine
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