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https://www.readbyqxmd.com/read/28791888/removal-of-organics-by-combined-process-of-coagulation-chlorination-ultrafiltration-optimization-of-overall-operation-parameters
#1
Gongduan Fan, Zhaoyue Su, Rujing Lin, Zhuwu Jiang, Renxing Xu, Shumin Wang
In order to gain the run parameters of the combined process of coagulation/in situ chlorination/ultrafiltration (UF) so that the system can remove as much organic contaminants as possible without serious membrane fouling, the impacts of operation conditions in coagulation and pre-chlorination unit on organics removal and membrane fouling rate were investigated in a pilot-scale test. The characteristics of organics in UF influent were examined by using the method of excitation emission matrix spectroscopy (EEMs) to find out fouling behavior of different natural organic matter (NOM) compositions to UF membrane...
August 9, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28780265/selective-enhancement-and-verification-of-woody-biomass-digestibility-as-a-denitrification-carbon-source
#2
Rongting Hu, Xilai Zheng, Jia Xin, Zhaoyue Sun, Tianyuan Zheng
The denitrification efficiency of woody biomass as carbon source is low because of its poor carbon availability. In this study, representative poplar sawdust was pretreated with lime and peracetic acid to enhance the biomass digestibility to different degrees; sawdust was then mixed with soil to investigate its denitrification efficiency. Under controllable conditions (25-95°C, 12-24h, varying dosages), sawdust digestibility (characterized by reducing sugar yield) was selectively enhanced 1.0-21.8 times over that of the raw sawdust (28...
July 29, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28760324/the-role-of-plant-growth-promoting-bacteria-in-metal-phytoremediation
#3
Zhaoyu Kong, Bernard R Glick
Phytoremediation is a promising technology that uses plants and their associated microbes to clean up contaminants from the environment. In recent years, phytoremediation assisted by plant growth-promoting bacteria (PGPB) has been highly touted for cleaning up toxic metals from soil. PGPB include rhizospheric bacteria, endophytic bacteria and the bacteria that facilitate phytoremediation by other means. This review provides information about the traits and mechanisms possessed by PGPB that improve plant metal tolerance and growth, and illustrate mechanisms responsible for plant metal accumulation/translocation in plants...
2017: Advances in Microbial Physiology
https://www.readbyqxmd.com/read/28741661/effect-of-dietary-resveratrol-supplementation-on-meat-quality-muscle-antioxidative-capacity-and-mitochondrial-biogenesis-of-broilers
#4
Cheng Zhang, Lei Yang, Xiaohui Zhao, Xingyong Chen, Li Wang, Zhaoyu Geng
BACKGROUND: The naturally occurring polyphenol resveratrol has been acknowledged with many beneficial biological effects. The aim of this study was to evaluate the influence of dietary resveratrol supplementation on meat quality, muscle antioxidative capacity and mitochondrial biogenesis of broilers. One hundred and eighty 21-d-old male Cobb broilers were randomly assigned to two groups and fed on a 0 mg kg(-1) or 400 mg kg(-1) resveratrol-supplemented diet for 21 d. Then, chickens were slaughtered and pectoralis major muscle (PM) samples were collected for analysis...
July 25, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28728543/integrative-analysis-of-the-pekin-duck-anas-anas-micrornaome-during-feather-follicle-development
#5
Xingyong Chen, Kai Ge, Min Wang, Cheng Zhang, Zhaoyu Geng
BACKGROUND: The quality and yield of duck feathers are very important economic traits that might be controlled by miRNA regulation. The aim of the present study was to investigate the mechanism underlying the crosstalk between individual miRNAs and the activity of signaling pathways that control the growth of duck feathers during different periods. We therefore conducted a comprehensive investigation using Solexa sequencing technology on the Pekin duck microRNAome over six stages of feather development at days 11, 15, and 20 of embryonic development (during the hatching period), and at 1 day and 4 and 10 weeks posthatch...
July 20, 2017: BMC Developmental Biology
https://www.readbyqxmd.com/read/28711804/effect-of-iron-iii-ion-on-moso-bamboo-pyrolysis-under-microwave-irradiation
#6
Qing Dong, Xiangqian Li, Zhaoyu Wang, Yanhong Bi, Rongling Yang, Jinfeng Zhang, Hongzhen Luo, Miaomiao Niu, Bo Qi, Chen Lu
The effect of iron(III) ion on microwave pyrolysis of moso bamboo was investigated. Hydrofluoric acid washing was used as a pilot process to demineralize moso bamboo in order to eliminate the influences of the other inorganics contained in moso bamboo itself. The results indicated that the addition of iron(III) ion increased the maximal reaction temperatures under microwave condition dependent on the amount of the added iron(III) ion. The production of the non-condensable gases was promoted by the addition of iron(III) ion mainly at the expense of liquid products...
July 5, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28659345/ablation-of-neuropilin-1-in-myeloid-cells-exacerbates-high-fat-diet-induced-insulin-resistance-through-nlrp3-inflammasome-in-vivo
#7
Xiaoyan Dai, Imoh Okon, Zhaoyu Liu, Tatiana Bedarida, Qilong Wang, Tharmarajan Ramprasath, Miao Zhang, Ping Song, Ming-Hui Zou
Neuropilin 1 (Nrp1), a co-receptor for class 3 semaphorins and growth factors, is highly expressed in vascular cells and myeloid cells including macrophages. Unlike well characterized pro-angiogeneic functions of endothelial cell Nrp1, the contributions of macrophage Nrp1 within the context of metabolic dysfunction remain to be established. The aim of this study was to determine the contributions of macrophage Nrp1 in high-fat diet (HFD; 60% kcal, 16 weeks)-instigated insulin resistance in vivo Insulin sensitivity and Nlrp3 inflammasome activation were monitored in HFD-fed wild-type (WT) and myeloid cell-specific Nrp1 knockout (Nrp1(myel-KO)) mice...
June 28, 2017: Diabetes
https://www.readbyqxmd.com/read/28654297/eriodictyol-not-its-glucuronide-metabolites-attenuates-acetaminophen-induced-hepatotoxicity
#8
Ling Ye, Zhaoyu Wang, Yao Lan, Minghao Chen, Cailing Wen, Yanxian Hu, Zhong Qiu Liu
Acetaminophen (APAP) is one of the most commonly used oral analgesics and antipyretics, but hepatotoxicity including liver failure may occur after overdose. The therapeutic options for treating APAP hepatotoxicity are limited. Eriodictyol, a dietary flavonoid with anti-inflammatory and antioxidant properties, was used here to determine its protective effects against APAP-induced hepatotoxicity in mice. Various administration routes and pharmacokinetics-pharmacodynamics (PK-PD) analyses were used to determine these effects...
June 27, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28646221/aberrant-activation-of-the-human-sex-determining-gene-in-early-embryonic-development-results-in-postnatal-growth-retardation-and-lethality-in-mice
#9
Tatsuo Kido, Zhaoyu Sun, Yun-Fai Chris Lau
Sexual dimorphisms are prevalent in development, physiology and diseases in humans. Currently, the contributions of the genes on the male-specific region of the Y chromosome (MSY) in these processes are uncertain. Using a transgene activation system, the human sex-determining gene hSRY is activated in the single-cell embryos of the mouse. Pups with hSRY activated (hSRY(ON)) are born of similar sizes as those of non-activated controls. However, they retard significantly in postnatal growth and development and all die of multi-organ failure before two weeks of age...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28635304/the-relationship-between-the-neutrophil-lymphocyte-ratio-and-in-stent-restenosis-in-patients-with-femoropopliteal-chronic-total-occlusions
#10
Zhihui Chang, Jiahe Zheng, Zhaoyu Liu, Qiyong Guo
We investigated the relationship between the neutrophil-lymphocyte ratio (NLR) and in-stent restenosis (ISR) in patients with femoropopliteal chronic total occlusions (CTOs). The study enrolled 180 patients who had undergone successful stenting treatment for femoropopliteal CTO. Patients with ISR were subsequently classified into 2 groups: early-ISR (within 1 year) and late-ISR (after 1 year). The clinical characteristics, angiographic data, and follow-up data were recorded. The baseline NLR was significantly higher in the early-ISR group than that in the non-ISR group [3...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28634078/astrocytes-regulate-the-expression-of-sp1r3-on-oligodendrocyte-progenitor-cells-through-cx47-and-promote-their-proliferation
#11
Dan Xu, Zhaoyu Liu, Shang Wang, Yan Peng, Xiaochuan Sun
Many degenerative diseases of the central nervous system are associated with demyelination. Oligodendrocyte progenitor cells (OPCs) are potential stem cells that can differentiate into various cell types, including oligodendrocytes (OLs). Promoting the proliferation and differentiation of OPCs into mature OLs that can myelinate axons is the key to stimulate remyelination. Here, we report that astrocytes (ASTs) increase the number of sphingosine-1-phosphate receptors 3 (S1pR3) on OPCs and promote OPCs proliferation through a direct contact via connexin 47 (Cx47)...
August 26, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28626237/cd4-t-cells-memorize-obesity-and-promote-weight-regain
#12
Jianghuan Zou, Beibei Lai, Mingzhu Zheng, Qin Chen, Shujun Jiang, Anying Song, Zan Huang, Peiliang Shi, Xin Tu, Di Wang, Linrong Lu, Zhaoyu Lin, Xiang Gao
Body weight regain often causes failure of obesity therapies while the underlying mechanism remains largely unknown. In this study, we report that immune cells, especially CD4+ T cells, mediate the 'memory' of previous obese status. In a weight gain-loss-regain model, we found that C57BL/6J mice with an obesity history showed a much faster rate of body weight regain. This obesity memory could last for at least 2 months after previously obese mice were kept at the same body weight as non-obese mice. Surprisingly, such obesity memory was abrogated by dexamethasone treatment, whereas immunodeficient Rag1(-/-) and H2A(-/-) mice failed to establish such memory...
June 19, 2017: Cellular & Molecular Immunology
https://www.readbyqxmd.com/read/28569795/cystatin-c-as-a-potential-therapeutic-mediator-against-parkinson-s-disease-via-vegf-induced-angiogenesis-and-enhanced-neuronal-autophagy-in-neurovascular-units
#13
Jing Zou, Zhaoyu Chen, Xiaobo Wei, Zhigang Chen, Yongmei Fu, Xiaoyan Yang, Dan Chen, Rui Wang, Peter Jenner, Jia-Hong Lu, Min Li, Zhuohua Zhang, Beisha Tang, Kunlin Jin, Qing Wang
Cystatin C (CYS C, Cst3) is an endogenous cysteine protease inhibitor that plays neuroprotective roles in neurodegenerative diseases. We aimed to explore the association of CYS C with Parkinson's disease (PD) models and investigate its involvement in the role of neurovascular units (NVUs) in PD neuro-pathogenesis. We used A53T α-synuclein (SNCA) transgenic mice and 6-hydroxydopamine-lesioned DAergic PC12 cells as experimental PD models to investigate the mechanisms behind this association. The injections of CYS C were administered to the right substantia nigra (SN) of A53T SNCA transgenic mice to measure the effects of CYS C in transgenic A53T SNCA mice...
June 1, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28569753/ultrafast-terahertz-snapshots-of-excitonic-rydberg-states-and-electronic-coherence-in-an-organometal-halide-perovskite
#14
Liang Luo, Long Men, Zhaoyu Liu, Yaroslav Mudryk, Xin Zhao, Yongxin Yao, Joong M Park, Ruth Shinar, Joseph Shinar, Kai-Ming Ho, Ilias E Perakis, Javier Vela, Jigang Wang
How photoexcitations evolve into Coulomb-bound electron and hole pairs, called excitons, and unbound charge carriers is a key cross-cutting issue in photovoltaics and optoelectronics. Until now, the initial quantum dynamics following photoexcitation remains elusive in the hybrid perovskite system. Here we reveal excitonic Rydberg states with distinct formation pathways by observing the multiple resonant, internal quantum transitions using ultrafast terahertz quasi-particle transport. Nonequilibrium emergent states evolve with a complex co-existence of excitons, carriers and phonons, where a delayed buildup of excitons under on- and off-resonant pumping conditions allows us to distinguish between the loss of electronic coherence and hot state cooling processes...
June 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28557019/development-of-a-validated-uplc-ms-ms-method-for-determination-of-humantenmine-in-rat-plasma-and-its-application-in-pharmacokinetics-and-bioavailability-studies
#15
Yanxian Hu, Minghao Chen, Zhaoyu Wang, Yao Lan, Lan Tang, Menghua Liu, Jie Zhao, Ming Hu, Lulu Zhang, Ling Ye
Humantenmine (HMT), the most toxic compound isolated from Gelsemium elegans Benth, is a well-known active herbal compound. A rapid and sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated to estimate the absolute oral bioavailability of HMT in rats. Quantification was performed by multiple reaction monitoring using electrospray ionization operated in positive ion mode with transitions of m/z 327.14 → m/z 296.19 for HMT and m/z 323.20 → m/z 236...
May 30, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28554805/genomics-of-sex-hormone-receptor-signaling-in-hepatic-sexual-dimorphism
#16
Daoshan Zheng, Xiao Wang, Per Antonson, Jan-Åke Gustafsson, Zhaoyu Li
The liver plays a crucial role in a variety of physiological processes. Sexual dimorphism is markedly defined in liver disorders, such as fatty liver diseases and liver cancer, but barely addressed in the normal liver. Distinct sex hormone signaling between male and female livers is the major driving factor for hepatic sexual dimorphism. Over 6000 genes are differently expressed between male and female livers in mice. Here we address how sex hormone receptors, estrogen receptor alpha (ERα) and androgen receptor (AR), mediate sexually dimorphic gene expression in mouse livers...
May 26, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28548224/resveratrol-beneficially-affects-meat-quality-of-heat-stressed-broilers-which-is-associated-with-changes-in-muscle-antioxidant-status
#17
Cheng Zhang, Xiaohui Zhao, Li Wang, Lei Yang, Xingyong Chen, Zhaoyu Geng
This study was conducted to evaluate the effect of dietary resveratrol (Res) supplementation on serum parameters, meat quality and muscle antioxidant status of broilers under heat stress (HS). A total of 270 21-day-old male Cobb broilers were randomly assigned to three treatment groups with six replicates of 15 birds each. The three treatment groups were as follows: the control group, in which birds were reared at 22 ± 1°C, and the HS and HS + Res (400 mg/kg) groups, in which birds were reared at 33 ± 1°C for 10 h (08...
May 26, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28535417/ezrin-nf-kb-activation-regulates-epithelial-mesenchymal-transition-induced-by-egf-and-promotes-metastasis-of-colorectal-cancer
#18
Yingru Li, Zhaoyu Lin, Bin Chen, Shuang Chen, Zhipeng Jiang, Taicheng Zhou, Zehui Hou, Youyuan Wang
There is growing evidence that epithelial mesenchymal-transition (EMT) plays significant roles in terms of tumor metastasis. There are a lot of cytokines inducing EMT of tumor cells, EGF is one of the important cytokines.Ezrin is a connexin between the cytoskeleton and the cell membrane, which is closely related to the morphological movement and metastasis of tumor cells.EGF can activate Ezrin and affects cell motility. In recent years, many studies have shown that NF-kB acts as an important transcription factor, involving in the process of EMT...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28527107/an-immune-related-six-lncrna-signature-to-improve-prognosis-prediction-of-glioblastoma-multiforme
#19
Meng Zhou, Zhaoyue Zhang, Hengqiang Zhao, Siqi Bao, Liang Cheng, Jie Sun
Recent studies have demonstrated the utility and superiority of long non-coding RNAs (lncRNAs) as novel biomarkers for cancer diagnosis, prognosis, and therapy. In the present study, the prognostic value of lncRNAs in glioblastoma multiforme was systematically investigated by performing a genome-wide analysis of lncRNA expression profiles in 419 glioblastoma patients from The Cancer Genome Atlas (TCGA) project. Using survival analysis and Cox regression model, we identified a set of six lncRNAs (AC005013.5, UBE2R2-AS1, ENTPD1-AS1, RP11-89C21...
May 19, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28504079/a-novel-nonsense-nbeal2-gene-mutation-causing-severe-bleeding-in-a-patient-with-gray-platelet-syndrome
#20
Lijuan Cao, Jian Su, Jiaming Li, Ziqiang Yu, Xia Bai, Zhaoyue Wang, Lijun Xia, Changgeng Ruan
Gray platelet syndrome (GPS) is a rare, inherited bleeding disorder characterized by the defect of platelet α-granule. Up to date, these are only four studies identifying NBEAL2 gene correlated with GPS. In the current report, we present a Chinese GPS patient who had severe bleeding tendency, abnormalities of platelet functions, and absence of platelet α-granules. Genomic DNA sequencing for the patient identified a nonsense mutation (g.27713C>A) of NBEAL2 gene (g.NG_031914.1) resulting in a premature protein (p...
May 15, 2017: Platelets
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