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Jamie A Davies

Joshua N Hook, David Boan, Don E Davis, Jamie D Aten, John M Ruiz, Thomas Maryon
Hospital safety culture is an integral part of providing high quality care for patients, as well as promoting a safe and healthy environment for healthcare workers. In this article, we explore the extent to which cultural humility, which involves openness to cultural diverse individuals and groups, is related to hospital safety culture. A sample of 2011 hospital employees from four hospitals completed measures of organizational cultural humility and hospital safety culture. Higher perceptions of organizational cultural humility were associated with higher levels of general perceptions of hospital safety, as well as more positive ratings on non-punitive response to error (i...
October 17, 2016: Journal of Clinical Psychology in Medical Settings
Erin Davis, Carlo Marra, John-Michael Gamble, Jamie Farrell, Joe Lockyer, J Mark FitzGerald, Waseem Abu-Ashour, Charlie Gillis, John Hawboldt
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are often nonadherent with medications and have poor inhaler technique. Community pharmacists can help to improve health-related quality of life and overall outcomes in patients with COPD. We aim to measure the effectiveness of a systematic, pharmacist-driven intervention on patients with diagnosed COPD. METHODS/DESIGN: This pragmatic, parallel-group, cluster randomized controlled trial is designed to determine the effectiveness of a multifactorial, pharmacist-led intervention on medication adherence, inhaler technique, health-related quality of life, health care resource utilization including COPD exacerbations, and use of medications...
October 13, 2016: Trials
Paul K Whelton, Paula T Einhorn, Paul Muntner, Lawrence J Appel, William C Cushman, Ana V Diez Roux, Keith C Ferdinand, Mahboob Rahman, Herman A Taylor, Jamy Ard, Donna K Arnett, Barry L Carter, Barry R Davis, Barry I Freedman, Lisa A Cooper, Richard Cooper, Patrice Desvigne-Nickens, Nara Gavini, Alan S Go, David J Hyman, Paul L Kimmel, Karen L Margolis, Edgar R Miller, Katherine T Mills, George A Mensah, Ann M Navar, Gbenga Ogedegbe, Michael K Rakotz, George Thomas, Jonathan N Tobin, Jackson T Wright, Sung Sug Sarah Yoon, Jeffrey A Cutler
No abstract text is available yet for this article.
November 2016: Hypertension
Jamie I Baum, Tyrone A Washington, Stephanie A Shouse, Walter Bottje, Sami Dridi, Gina Davis, Dameon Smith
Obesity is a major public health concern and it is essential to identify effective treatments and preventative strategies to stop continued increases in obesity rates. The potential functional roles of the branched chain amino acid leucine make this amino acid an attractive candidate for the treatment and/or prevention of obesity. The objective of this study was to determine if long-term leucine supplementation could prevent the development of obesity and reduce the risk factors for chronic disease in rats fed a high-fat (60 % fat) diet...
August 20, 2016: Journal of Physiology and Biochemistry
Bethany R Baumgart, Faye Wang, Jae Kwagh, Chris Storck, Catherine Euler, Megan Fuller, Damir Simic, Suresh Sharma, Jamie J Arnold, Craig E Cameron, Terry R Van Vleet, Oliver Flint, Roderick T Bunch, Marc H Davies, Michael J Graziano, Thomas P Sanderson
BMS-986094, the prodrug of a guanosine nucleotide analogue (2'-C-methylguanosine), was withdrawn from clinical trials due to serious safety issues. Nonclinical investigative studies were conducted as a follow up to evaluate the potential for BMS-986094-related mitochondrial-toxicity. In vitro, BMS-986094 was applied to human hepatoma cells (HepG2 and Huh-7) or cardiomyocytes (hiPSCM) up to 19 days to assess mitochondrial DNA content and specific gene expression. There were no mitochondrial DNA changes at concentrations ≤10 µM...
October 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
Jamie L Wagner, Rachel M Kenney, Jose A Vazquez, Tamer A Ghanem, Susan L Davis
BACKGROUND: The purpose of this study was to determine the incidence of and risk factors for surgical site infections in microvascular reconstruction for patients with head and neck cancer. METHODS: One hundred seventeen patients with head and neck cancer undergoing microvascular reconstruction received postoperative surgical infection prophylaxis and were followed for 30 days. Surgical infection prophylaxis was categorized by empiric spectrum of activity. Risk factors for surgical site infection development and cumulative incidence of surgical site infections were characterized...
October 2016: Head & Neck
H Tweeddale, C L Hawkins, J F Jamie, R J W Truscott, M J Davies
Long wavelength solar UV radiation is implicated in photodamage to the human eye. The human lens contains multiple tryptophan-derived compounds that have significant absorbance bands in the UVA region (λ 315 - 400 nm) that act as efficient physical filters for these wavelengths. The concentrations of many of these UV filter compounds decrease with increasing age, resulting in diminished protection, increased oxidative damage and the accumulation of modified proteins implicated in nuclear cataract formation...
July 7, 2016: Free Radical Research
Jamie B Morris, Donald L Goss, Erin M Florkiewicz, Irene S Davis
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
José M Menchón, Michael van Ameringen, Bernardo Dell'Osso, Damiaan Denys, Martijn Figee, Jon E Grant, Eric Hollander, Donatella Marazziti, Humberto Nicolini, Stefano Pallanti, Christian Ruck, Roseli Shavitt, Dan J Stein, Erik Andersson, Rajshekhar Bipeta, Danielle C Cath, Lynne Drummond, Jamie Feusner, Daniel A Geller, Georgi Hranov, Christine Lochner, Hisato Matsunaga, Randy E McCabe, Davis Mpavaenda, Takashi Nakamae, Richard O'Kearney, Massimo Pasquini, Ricardo Pérez Rivera, Michael Poyurovsky, Eva Real, Maria Conceição do Rosário, Noam Soreni, Richard P Swinson, Nienke Vulink, Joseph Zohar, Naomi Fineberg
In recent years, many assessment and care units for obsessive-compulsive disorder (OCD) have been set up in order to detect, diagnose and to properly manage this complex disorder, but there is no consensus regarding the key functions that these units should perform. The International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) together with the Obsessive Compulsive and Related Disorders Network (OCRN) of the European College of Neuropsychopharmacology (ECNP) and the Anxiety and Obsessive Compulsive Disorders Section of the World Psychiaric Association (WPA) has developed a standards of care programme for OCD centres...
September 2016: International Journal of Psychiatry in Clinical Practice
Kevin Hamilton, Christine Davis, Jamie Falk, Alex Singer, Shawn Bugden
Background Drug-related problems have been identified as a major contributor to emergency room visits, hospitalizations, and death. The most commonly implicated medications are nonsteroidal anti-inflammatory drugs (NSAIDs), antiplatelets, and anticoagulants. Considering a significant proportion of these harms are preventable, indicators to identify risky prescribing before they lead to harm have been developed. Objective To examine the prevalence and patterns of potentially inappropriate prescriptions (PIPs) in a primary care population who are using high-risk medications...
October 2016: International Journal of Clinical Pharmacy
Jwu Jin Khong, Kathryn P Burdon, Yi Lu, Lefta Leonardos, Kate J Laurie, John P Walsh, Adam D Gajdatsy, Peter R Ebeling, Alan A McNab, Thomas G Hardy, Richard J Stawell, Garry J Davis, Dinesh Selva, Angelo Tsirbas, Grant W Montgomery, Stuart Macgregor, Jamie E Craig
PURPOSE: Thyroid-associated orbitopathy (TO) is an autoimmune-mediated orbital inflammation that can lead to disfigurement and blindness. Multiple genetic loci have been associated with Graves' disease, but the genetic basis for TO is largely unknown. This study aimed to identify loci associated with TO in individuals with Graves' disease, using a genome-wide association scan (GWAS) for the first time to our knowledge in TO. METHODS: Genome-wide association scan was performed on pooled DNA from an Australian Caucasian discovery cohort of 265 participants with Graves' disease and TO (cases) and 147 patients with Graves' disease without TO (controls)...
June 1, 2016: Investigative Ophthalmology & Visual Science
Brenda M Davy, A Hope Jahren, Valisa E Hedrick, Wen You, Jamie M Zoellner
OBJECTIVE: Controversy exists surrounding the health effects of added sugar (AS) and sugar-sweetened beverage (SSB) intakes, primarily due to a reliance on self-reported dietary intake. The purpose of the current investigation was to determine if a 6-month intervention targeting reduced SSB intake would impact δ13C AS intake biomarker values. DESIGN: A randomized controlled intervention trial. At baseline and at 6 months, participants underwent assessments of anthropometrics and dietary intake...
June 14, 2016: Public Health Nutrition
Jamie A Davies, Elise Cachat
Classical tissue engineering is aimed mainly at producing anatomically and physiologically realistic replacements for normal human tissues. It is done either by encouraging cellular colonization of manufactured matrices or cellular recolonization of decellularized natural extracellular matrices from donor organs, or by allowing cells to self-organize into organs as they do during fetal life. For repair of normal bodies, this will be adequate but there are reasons for making unusual, non-evolved tissues (repair of unusual bodies, interface to electromechanical prostheses, incorporating living cells into life-support machines)...
June 15, 2016: Biochemical Society Transactions
Marieke A de Graaff, Jamie S E Yu, Hannah C Beird, Davis R Ingram, Theresa Nguyen, Jeffrey Juehui Liu, Svetlana Bolshakov, Károly Szuhai, Pierre Åman, Keila E Torres, Dina Lev, Torsten O Nielsen, Judith V M G Bovée, Alexander J Lazar, Neeta Somaiah
Myxoid liposarcoma has the pathognomonic fusion oncogene FUS-DDIT3 encoding a chimeric transcription factor. Metastatic risk is higher with an increased round cell component and has been linked to aberrations involving the IGFR/PI3K/AKT pathway. These molecular insights have yet to translate to targeted therapies, and the lack of experimental models is a major hindrance. We describe the initial in-depth characterization of a new cell line (DL-221) and establishment of a mouse xenograft model. The cell line DL-221 was derived from a metastatic pleural lesion showing myxoid and round cell histology...
August 2016: Laboratory Investigation; a Journal of Technical Methods and Pathology
Jamie K Lim, Jeffrey P Bratberg, Corey S Davis, Traci C Green, Alexander Y Walley
In March of 2015, the United States Department of Health and Human Services identified 3 priority areas to reduce opioid use disorders and overdose, which are as follows: opioid-prescribing practices; expanded use and distribution of naloxone; and expansion of medication-assisted treatment. In this narrative review of overdose prevention and the role of prescribers and pharmacists in distributing naloxone, we address these priority areas and present a clinical scenario within the review involving a pharmacist, a patient with chronic pain and anxiety, and a primary care physician...
September 2016: Journal of Addiction Medicine
Matthew J Davis, Kelly M Moore, Katherine Meyers, Jamie Mathews, Erin O Zerth
Although the majority of mental health conditions are treated in primary care, treatment provided in this setting is often inadequate. In response to this problem, integrated mental health programs were created to enhance direct patient care and increase support for primary care providers. Data on the efficacy of these programs have suggested improved access, treatment outcomes, and patient satisfaction. However, infrequently examined is how interaction with integrated mental health providers impacts completion of referrals to specialty mental health (SMH) programs for patients whose treatment needs are too severe to treat in primary care alone...
May 30, 2016: Psychological Services
Michael P Veve, Jamie L Wagner, Rachel M Kenney, Jenny L Grunwald, Susan L Davis
Extended-spectrum β-lactamase (ESBL) enzymes cause resistance to common β-lactam antibiotics and are associated with poor outcomes. Management of ESBL urinary tract infections (UTIs) is challenging given the limited treatment options available outside the hospital setting. In this study, the primary endpoint of UTI-related 30-day hospital re-admission or emergency department/clinic revisit rates was compared for fosfomycin and ertapenem outpatient ESBL UTI treatments. A retrospective cohort study was performed on patients with ESBL UTIs treated with outpatient fosfomycin or ertapenem from January 2010 to February 2015...
July 2016: International Journal of Antimicrobial Agents
Christopher C Cranston, Katherine E Miller, Joanne L Davis, Jamie L Rhudy
Nightmares and sleep disturbances are gaining attention as targets of treatment interventions for trauma-exposed populations. Measures in trials evaluating these interventions tend to utilize proprietary measures of nightmare characteristics, which makes it challenging to compare findings across studies. The Trauma-Related Nightmare Survey is a questionnaire that was initially developed for utilization in efficacy studies of Exposure, Relaxation, and Rescripting Therapy. Preliminary examinations of the psychometric properties have demonstrated good test-retest reliability and convergent validity...
May 26, 2016: Journal of Trauma & Dissociation
Kareena McAloney-Kocaman, Karen Lorimer, Paul Flowers, Mark Davis, Christina Knussen, Jamie Frankis
Associations of sexual identity with a range of sexual and sexual health behaviours were investigated amongst men who have sex with men (MSM). Data from 1816 MSM recruited from 4 Celtic nations (Scotland, Wales, Northern Ireland and the Republic of Ireland) were collected via a cross-sectional online survey advertised via social media. About 18.3% were non-gay identified MSM (NGI-MSM). In the last year, 30% of NGI-MSM reported high-risk unprotected anal intercourse and 45% reported never having had an sexually transmitted infection (STI) test...
August 2016: Global Public Health
Nathaniel J Rhodes, Jamie L Wagner, Elise M Gilbert, Page E Crew, Susan L Davis, Marc H Scheetz
Benchmarks for antimicrobial consumption measured in antimicrobial days are beginning to emerge. The relationship between the traditional measure of days of therapy and antimicrobial days is unclear. We observed a high intermethod correlation (R2=0.99): antimicrobial days were 1.9-fold lower than days of therapy across agents. Individual institutions should correlate these measures. Infect Control Hosp Epidemiol 2016;37:971-973.
August 2016: Infection Control and Hospital Epidemiology
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