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https://www.readbyqxmd.com/read/28239755/increasing-cancer-screening-among-old-order-anabaptist-women-through-specialized-women-s-health-and-integrated-cancer-screening-interventions
#1
Kate McBride, Dionne Gesink
Our objective was to develop, deliver, and evaluate a cancer screening intervention focused on rural Anabaptist communities in Ontario, Canada, to increase routine cancer screenings among women. We carried out three cancer prevention and screening interventions with Old Order Anabaptist women. Each intervention consisted of: transportation to the site, pre-arranged screening services, health teachings, fellowship and shopping, and an evaluative survey. Seventy five women total participated over three interventions...
February 27, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28239394/standardization-and-validation-of-dot-elisa-assay-for-paracoccidioides-brasiliensis-antibody-detection
#2
Camila Mika Kamikawa, Rinaldo Poncio Mendes, Adriana Pardini Vicentini
BACKGROUND: Paracoccidioidomycosis (PCM) is a neglected systemic mycosis caused by a dimorphic fungus of the Paracoccidioides genus. The standard diagnosis is based on isolation of the fungi in culture, and by microscopic visualization of characteristic multiple budding yeast cells in biological samples. However, in some situations, access to the site of injury prevents the collection of biological material. A variety of immuno-serological techniques has proven useful for allowing inferring diagnosis with a certain degree of certainty, thus optimizing time...
2017: Journal of Venomous Animals and Toxins Including Tropical Diseases
https://www.readbyqxmd.com/read/28239319/prevalence-of-hepatitis-b-hepatitis-c-and-human-immunodeficiency-viral-infections-in-patients-with-inflammatory-bowel-disease-in-north-india
#3
Parnita Harsh, Vipin Gupta, Saurabh Kedia, Sawan Bopanna, Sucharita Pilli, Surendernath, Govind Kumar Makharia, Vineet Ahuja
BACKGROUND/AIMS: Patients with inflammatory bowel disease (IBD) often require immunosuppressive therapy and blood transfusions and therefore are at a high risk of contracting infections due to hepatitis B (HBV) and hepatitis C (HCV) and human immunodeficiency virus (HIV). In the present study, we assessed the prevalence of these infections in patients with IBD. METHODS: This retrospective study included 908 consecutive patients with IBD (ulcerative colitis [UC], n=581; Crohn's disease [CD], n=327) who were receiving care at a tertiary care center...
January 2017: Intestinal Research
https://www.readbyqxmd.com/read/28238983/screening-for-food-insecurity-in-pediatric-primary-care-a-clinic-s-positive-implementation-experiences
#4
Elizabeth Adams, Dana Hargunani, Laurel Hoffmann, Gregory Blaschke, Joanna Helm, Anneliese Koehler
Our project's purpose was to assess the acceptability of a screening and intervention program to address food insecurity (FI) in pediatric primary care. We implemented systematic FI screening during routine health supervision visits. Our positive results can help to inform implementation of routine FI screening in clinical practice.
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28238425/reliable-screening-and-confirmation-of-156-multi-class-illegal-adulterants-in-dietary-supplements-based-on-extracted-common-ion-chromatograms-by-ultra-high-performance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry
#5
Eun Hye Kim, Hee Seung Seo, Nam Yong Ki, Na-Hyun Park, Wonwoong Lee, Jung Ah Do, Sungkwan Park, Sun Young Baek, Bongjin Moon, Han Bin Oh, Jongki Hong
An analytical method for the reliable screening and confirmation of 156 illegal drugs (58 erectile dysfunction drugs, 49 synthetic steroids, 26 anabolic steroids, and 23 anti-histamine drugs) in supplementary diets using ultra-high-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry (UHPLC-Q/TOF-MS) was developed. Various types of supplements (liquid, capsule, powder, pill and tablet) with complicated matrices were pretreated by simple liquid-liquid extraction. The wide scope of 156 target compounds was effectively determined within 15min in the positive ion mode, detecting the compounds at a sub-ppb level...
February 20, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28237127/-prevalence-and-risk-factors-for-sickle-retinopathy-in-a-sub-saharan-comprehensive-sickle-cell-center
#6
A K Dembélé, B A Toure, Y S Sarro, A Guindo, B Fané, L Offredo, S Kené, I Conaré, O Tessougué, Y Traoré, Y Badiaga, M B Sidibé, D Diabaté, M Coulibaly, M Kanta, B Ranque, D A Diallo
INTRODUCTION: Retinopathy is a chronic complication with severe functional consequences in patients with sickle cell disease. Its prevalence is not well known in sub-Saharan Africa because of the absence of screening. We report here the results of a routine screening for sickle retinopathy in a Comprehensive Sickle Cell Center in Sub-Saharan Africa. METHODS: Screening of sickle retinopathy was carried out in all sickle cell patients aged 10 and over, followed between 2010 and 2012...
February 22, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28237037/the-effect-size-of-type-2-diabetes-mellitus-on-tuberculosis-drug-resistance-and-adverse-treatment-outcomes
#7
Lucia Monserrat Perez-Navarro, Blanca I Restrepo, Francisco Javier Fuentes-Dominguez, Ravindranath Duggirala, Jaime Morales-Romero, Juan Carlos López-Alvarenga, Iñaki Comas, Roberto Zenteno-Cuevas
OBJECTIVE: To evaluate the effect size of type 2 diabetes mellitus (T2DM) on tuberculosis (TB) treatment outcomes and multi drug resistance (MDR). METHODS: A cohort with 507 individuals with diagnosed TB included 183 with coexistence of T2DM and TB (TB-T2DM). Participants were identified at the time of TB diagnosis and followed during the course of TB treatment. Then we computed relative risks and adjustments by Cox proportional hazards for outcome variables (drug resistance, death, relapse, treatment failure), and the size of their effect as Cohen's-d...
March 2017: Tuberculosis
https://www.readbyqxmd.com/read/28237002/congenital-hypothyroidism-role-of-nuclear-medicine
#8
REVIEW
Isabelle Keller-Petrot, Juliane Leger, Aline Sergent-Alaoui, Claire de Labriolle-Vaylet
Thyroid scintigraphy holds a key place in the etiologic workup of neonatal hypothyroidism. Routine screening for this disorder in maternity hospitals in industrialized countries, for nearly 40 years, has permitted early treatment and thereby helped to prevent its physical and mental complications. Neonatal hypothyroidism affects approximately 1 in 3000 births. The most common causes are abnormal thyroid gland development and defective hormone synthesis by an eutopic thyroid gland. The incidence of the latter has risen in recent years, for reasons that remain unclear...
March 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28236777/multidetector-ct-improving-surgical-outcomes-in-breast-cancer-miso-bc-a-randomised-controlled-trial
#9
Julie Cox, Helen Hancock, Rebecca Maier, Jonathan Spratt, Chooi May Lee, Amir Bhatti, James Mason
BACKGROUND: Early diagnosis of malignant axillary nodes in breast cancer guides the extent of axillary surgery: patients with known axillary malignancy receive a more extensive single operation at the same time as surgery to their breast. A multicentre randomised controlled trial assessed whether a Computed Tomography (CT) scan of the axilla could more accurately diagnose malignant axillary lymph node involvement in patients with newly diagnosed breast cancer when compared to usual care...
February 22, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28236343/tarseqqc-quality-control-on-targeted-sequencing-experiments-in-r
#10
Gabriela A Merino, Yanina A Murua, Cristóbal Fresno, Juan M Sendoya, Mariano Golubicki, Soledad Iseas, Mariana Coraglio, Osvaldo L Podhajcer, Andrea S Llera, Elmer A Fernández
Targeted sequencing is growing as a screening methodology used in research and medical genetics to identify genomic alterations causing human diseases. In general, a list of possible genomic variants is derived from mapped reads through a variant calling step. This processing step is usually based on variant coverage, although it may be affected by several factors. Therefore, under-covered relevant clinical variants may not be reported, impacting on pathology diagnosis or treatment. Thus, a prior quality control of the experiment is critical to determine variant detection accuracy and to avoid erroneous medical conclusions...
February 24, 2017: Human Mutation
https://www.readbyqxmd.com/read/28236334/pi-radsv2-how-we-do-it
#11
Matthew D Greer, Peter L Choyke, Baris Turkbey
: Much criticism has been leveled at screening for prostate cancer using prostate-specific antigen (PSA) testing, yet there is no suitable replacement to improve the detection of clinically significant cancer (CSC). Prostate multiparametric magnetic resonance imaging (mpMRI) combined with mpMRI-guided biopsies is one possible solution, as it reduces detection of low-grade disease and increases detection of CSC. However, mpMRI is critically limited by lack of standardization across institutions and low interobserver agreement...
February 25, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28231582/radiomics-in-head-and-neck-cancer-extracting-valuable-information-from-data-beyond-recognition
#12
Kathrin Scheckenbach, Lena Colter, Martin Wagenmann
In oncology, biomarkers that describe the characteristics of a malignancy on different levels (clinical, histological, molecular) and the patient's outcome and treatment response are increasingly integrated into the clinical routine. Extensive screening tools, "omics," offer incredible opportunities and vast amounts of data. During the last years, the field of "omics" gained a new promising partner, the "radiomics." Based on radiological imaging, multiple features can be extracted and linked to clinical, genomic, and histopathological data from other sources...
2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28231369/estimation-of-partitioning-of-airflow-in-septal-surgery-a-prospective-study-with-reference-to-the-nose-scale
#13
Indranil Sen, Mainak Dutta, Dibakar Haldar, Ramanuj Sinha
Improper patient selection for septal surgery often has been found to result in therapeutic failure, and there needs to be an objective assessment of nasal obstruction before the surgery and for postoperative follow-up that can be applied in the routine otolaryngology practice. The purpose of this study is to assess the usefulness of a cost-effective device for objective measurement of the nasal airway partitioning in selecting patients for septal surgery and for postoperative outcome evaluation. A hospital-based, prospective, observational study was carried out in a tertiary-care teaching institution involving 74 patients waiting for septal surgery...
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28231239/surveillance-for-health-care-access-and-health-services-use-adults-aged-18-64-years-behavioral-risk-factor-surveillance-system-united-states-2014
#14
Catherine A Okoro, Guixiang Zhao, Jared B Fox, Paul I Eke, Kurt J Greenlund, Machell Town
PROBLEM/CONDITION: As a result of the 2010 Patient Protection and Affordable Care Act, millions of U.S. adults attained health insurance coverage. However, millions of adults remain uninsured or underinsured. Compared with adults without barriers to health care, adults who lack health insurance coverage, have coverage gaps, or skip or delay care because of limited personal finances might face increased risk for poor physical and mental health and premature mortality. PERIOD COVERED: 2014...
February 24, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28228194/asymptomatic-metastatic-carcinoid-tumor-discovered-by-routine-screening-mammography
#15
Julia L Brothers, Mark A Mikhitarian, Lee S Fleischer
No abstract text is available yet for this article.
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28227728/comparison-between-users-of-a-new-methodology-for-heart-sound-auscultation
#16
Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Sandra S Mattos, Pedro Gomes, Miguel Y Coimbra
Auscultation is a routine exam and the first line of screening in heart pathologies. The objective of this study was to assess if using a new data collection system, the DigiScope Collector, with a guided and automatic annotation of heart auscultation, different levels of expertise/experience users could collect similar digital auscultations. Data were collected within the Heart Caravan Initiative (Paraíba, Brasil). Patients were divided into two study groups: Group 1 evaluated by a third year medical student (User 1), and an experienced nurse (User 2); Group 2 evaluated by User 2 and an Information Technology professional (User 3)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227433/microprinted-tumor-spheroids-enable-anti-cancer-drug-screening
#17
Pradip S Thakuri, Stephanie L Ham, Hossein Tavana, Pradip S Thakuri, Stephanie L Ham, Hossein Tavana, Stephanie L Ham, Hossein Tavana
Spheroids present a biologically relevant model of avascular tumors and a unique tool for discovery of anti-cancer drugs. Despite being used in research laboratories for several decades, spheroids are not routinely used for drug discovery primarily due to the difficulty of mass-producing uniformly-sized spheroids and intense labor involved in handling, drug treatment, and analyzing them. We overcome this barrier using a novel technology to robotically microprint spheroids in standard 384-well plates. An aqueous drop containing cancer cells is dispensed into a bath of a second, immiscible aqueous phase...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227200/obstructive-sleep-apnea-severity-estimation-fusion-of-speech-based-systems
#18
D Ben Or, E Dafna, A Tarasiuk, Y Zigel, D Ben Or, E Dafna, A Tarasiuk, Y Zigel, A Tarasiuk, Y Zigel, E Dafna
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder. Previous studies associated OSA with anatomical abnormalities of the upper respiratory tract that may be reflected in the acoustic characteristics of speech. We tested the hypothesis that the speech signal carries essential information that can assist in early assessment of OSA severity by estimating apnea-hypopnea index (AHI). 198 men referred to routine polysomnography (PSG) were recorded shortly prior to sleep onset while reading a one-minute speech protocol...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226584/leveraging-imu-data-for-accurate-exercise-performance-classification-and-musculoskeletal-injury-risk-screening
#19
Darragh Whelan, Martin O'Reilly, Bingquan Huang, Oonagh Giggins, Tahar Kechadi, Brian Caulfield, Darragh Whelan, Martin O'Reilly, Bingquan Huang, Oonagh Giggins, Tahar Kechadi, Brian Caulfield, Martin O'Reilly, Brian Caulfield, Oonagh Giggins, Tahar Kechadi, Darragh Whelan, Bingquan Huang
Inertial measurement units (IMUs) are becoming increasingly prevalent as a method for low cost and portable biomechanical analysis. However, to date they have not been accepted into routine clinical practice. This is often due to a disconnect between translating the data collected by the sensors into meaningful and actionable information for end users. This paper outlines the work completed by our group in attempting to achieve this. We discuss the conceptual framework involved in our work, the methodological approach taken in analysing sensor signals and discuss possible application models...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226399/wavelet-based-scaling-indices-for-breast-cancer-diagnostics
#20
T Roberts, M Newell, W Auffermann, B Vidakovic
Mammography is routinely used to screen for breast cancer. However, the radiological interpretation of mammogram images is complicated by the heterogeneous nature of normal breast tissue and the fact that cancers are often of the same radiographic density as normal tissue. In this work, we use wavelets to quantify spectral slopes of breast cancer cases and controls and demonstrate their value in classifying images. In addition, we propose asymmetry statistics to be used in forming features, which improve the classification result...
February 22, 2017: Statistics in Medicine
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