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https://www.readbyqxmd.com/read/28637139/translation-cross-cultural-adaptation-and-validation-of-the-persian-version-of-coop-wonca-charts-in-persian-speaking-iranians-with-multiple-sclerosis
#1
Morteza Taghipour, Mahyar Salavati, Seyed Massood Nabavi, Behnam Akhbari, Ismail Ebrahimi Takamjani, Hossein Negahban, Fatemeh Rajabzadeh
PURPOSE: Translation, cross-culturally adaptation and validation of a Persian version of COOP/WONCA charts in Persian-speaking Iranians with multiple sclerosis (MS). METHOD: The Persian version of COOP/WONCA charts was developed after a standard forward translation, synthesis and backward translation. A total of 197 subjects with MS participated in this study. They were asked to complete the COOP/WONCA charts and Short-Form 36 Health Survey (SF-36). The COOP/WONCA charts were re-administered to 50 patients, 4 weeks after the first session...
February 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28634548/decline-in-memory-visuospatial-ability-and-crystalized-cognitive-abilities-in-older-adults-normative-aging-or-terminal-decline
#2
R Bendayan, A M Piccinin, S M Hofer, D Cadar, B Johansson, G Muniz-Terrera
The aim of this study is to explore the pattern of change in multiple measures of cognitive abilities in a sample of oldest-old adults, comparing two different time metrics (chronological age and time to death) and therefore examining both underlying conceptual assumptions (age-related change and terminal decline). Moreover, the association with individual characteristics as sex, education, and dementia diagnosis was also examined. Measures of cognitive status (Mini-Mental State Examination and the Swedish Clock Test) and tests of crystallized (knowledge and synonyms), memory (verbal memory, nonverbal long-term memory, recognition and correspondence, and short-term memory), and visuospatial ability were included...
2017: Journal of Aging Research
https://www.readbyqxmd.com/read/28627275/the-effects-of-exercise-on-patient-reported-outcomes-and-performance-based-physical-function-in-adults-with-acute-leukemia-undergoing-induction-therapy
#3
Ashley Leak Bryant, Allison M Deal, Claudio L Battaglini, Brett Phillips, Mackenzi Pergolotti, Erin Coffman, Matthew C Foster, William A Wood, Charlotte Bailey, Anthony C Hackney, Deborah K Mayer, Hyman B Muss, Bryce B Reeve
INTRODUCTION: Fatigue is a distressing symptom for adults with acute leukemia, often impeding their ability to exercise. OBJECTIVES: 1) Examine effects of a 4-week mixed-modality supervised exercise program (4 times a week, twice a day) on fatigue in adults with acute leukemia undergoing induction chemotherapy. 2) Evaluate effects of exercise program on cognition, anxiety, depression, and sleep disturbance. 3) Evaluate effect of intervention on adherence to exercise...
March 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28625382/impact-of-continuous-positive-airway-pressure-and-oxygen-on-health-status-in-patients-with-coronary-heart-disease-cardiovascular-risk-factors-and-obstructive-sleep-apnea-a-heart-biomarker-evaluation-in-apnea-treatment-heartbeat-analysis
#4
Eldrin F Lewis, Rui Wang, Naresh Punjabi, Daniel J Gottlieb, Stuart F Quan, Deepak L Bhatt, Sanjay R Patel, Reena Mehra, Roger S Blumenthal, Jia Weng, Michael Rueschman, Susan Redline
INTRODUCTION: Obstructive sleep apnea (OSA) is associated with impaired health-related quality of life (HRQL). Treatment with continuous positive airway pressure (CPAP) has variable impacts on HRQL, and this may be influenced by patient's tolerance of therapy. The objective is to determine the impact of nocturnal supplemental oxygen (NSO) and CPAP on HRQL compared with healthy lifestyle education (HLSE) in individuals with OSA. METHODS: Patients with coronary heart disease (CHD) or at least 3 major CHD risk factors with apnea-hypopnea index of 15 to 50 events/h were randomized to CPAP, NSO, or HLSE...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28625107/associations-between-omega-3-fatty-acids-and-25-oh-d-and-psychological-distress-among-inuit-in-canada
#5
Hans-Ragnar Skogli, Dominique Geoffroy, Hope A Weiler, Grethe S Tell, Laurence J Kirmayer, Grace M Egeland
BACKGROUND: Inuit in Canada have experienced dietary changes over recent generations, but how this relates to psychological distress has not been investigated. OBJECTIVE: To evaluate how nutritional biomarkers are related to psychological distress. DESIGN: A total of 36 communities in northern Canada participated in the International Polar Year Inuit Health Survey (2007-2008). Of 2796 households, 1901 (68%) participated; 1699 Inuit adults gave blood samples for biomarker analysis and answered the Kessler 6-item psychological distress questionnaire (K6)...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28625092/factors-affecting-outcome-in-ocular-myasthenia-gravis
#6
Marco Mazzoli, Alessandra Ariatti, Franco Valzania, Shaniko Kaleci, Manuela Tondelli, Paolo F Nichelli, Giuliana Galassi
AIM OF THE STUDY: 50% to 60% of patients with ocular Myasthenia Gravis (OMG) progress to generalized disease (GMG) within 2 years.Aim of our study was to explore factors affecting prognosis of OMG and to test the predictive role of several independent clinical variables. MATERIALS AND METHODS: We reviewed a cohort of 168 Caucasian patients followed from September 2000 and January 2016. Several independent variables were considered as prognostic factors: gender, age of onset, results on electrophysiological tests, presence and level of antibodies against acetylcholine receptors (AChR-Abs), treatments, thymic abnormalities...
June 19, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28624753/treatment-of-asymptomatic-uti-in-older-delirious-medical-in-patients-a-prospective-cohort-study
#7
Monidipa Dasgupta, Chris Brymer, Sameer Elsayed
BACKGROUND: Despite clinical practice guidelines, asymptomatic bacteriuria (ASB) in older people is frequently treated. A common reason for treating ASB is a change in mental status. OBJECTIVE: To determine how often asymptomatic UTI is treated in older medically ill delirious individuals and its association with functional recovery. METHODS: Consecutive older medical in-patients were screened for delirium, and followed in hospital. Treatment for asymptomatic UTI was defined as documented treatment for a possible urinary tract infection with antibiotics, without concurrent infectious or urinary symptoms...
May 31, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28623755/effects-of-adjunctive-lacosamide-on-mood-and-quality-of-life-in-patients-with-epilepsy
#8
Luba Nakhutina, Saroj D Kunnakkat, Madeleine Coleman, Catherine Lushbough, Vanessa Arnedo, Nirali Soni, Arthur C Grant
We examined the effects of adjunctive lacosamide (LCM) on mood and quality of life (QOL) in adult patients with partial-onset seizures in a prospective, controlled, single-blind study. Patients in whom LCM was added to their AED regimen for clinical indications comprised the LCM group (n=18), while the control group (n=32) comprised patients on ≥2 AEDs with anticipated stable dosing for the duration of the study. Profile of Mood States (POMS) and QOLIE-89 were used to assess mood and QOL at enrollment and 12-16weeks later...
June 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28623152/singapore-healthy-older-people-everyday-hope-study-prevalence-of-frailty-and-associated-factors-in-older-adults
#9
Reshma A Merchant, Matthew Zhixuan Chen, Linda Wei Lin Tan, Moses YiDong Lim, Han Kwee Ho, Rob M van Dam
BACKGROUND: In the context of a rapidly ageing population, Singapore is anticipating a rise in multimorbidity, disability, and dependency, which are driven by physical frailty. Healthy Older People Everyday (HOPE) is an epidemiologic population-based study on community-dwelling older adults aged 65 years and older in Singapore. OBJECTIVE: To investigate the prevalence of frail and prefrail states and their association with polypharmacy, multimorbidity, cognitive and functional status, and perceived health status among community-dwelling older adults in Singapore...
June 13, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28622384/preventability-of-early-vs-late-readmissions-in-an-academic-medical-center
#10
Kelly L Graham, Ogechi Dike, Lauren Doctoroff, Marisa Jupiter, Anita Vanka, Roger B Davis, Edward R Marcantonio
BACKGROUND: It is unclear if the 30-day unplanned hospital readmission rate is a plausible accountability metric. OBJECTIVE: Compare preventability of hospital readmissions, between an early period [0-7 days post-discharge] and a late period [8-30 days post-discharge]. Compare causes of readmission, and frequency of markers of clinical instability 24h prior to discharge between early and late readmissions. DESIGN, SETTING, PATIENTS: 120 patient readmissions in an academic medical center between 1/1/2009-12/31/2010...
2017: PloS One
https://www.readbyqxmd.com/read/28619025/evaluating-the-effectiveness-of-a-healthy-lifestyle-clinician-in-addressing-the-chronic-disease-risk-behaviours-of-community-mental-health-clients-study-protocol-for-a-randomised-controlled-trial
#11
Caitlin Fehily, Kate Bartlem, John Wiggers, Paula Wye, Richard Clancy, David Castle, Sonia Wutzke, Chris Rissel, Andrew Wilson, Paul McCombie, Fionna Murphy, Jenny Bowman
BACKGROUND: People with a mental illness experience a greater morbidity and mortality from chronic diseases relative to the general population. A higher prevalence of modifiable health risk behaviours such as smoking, poor nutrition, physical inactivity and harmful alcohol consumption contribute substantially to this disparity. Despite clinical practice guidelines recommending that mental health services routinely provide care to address these risk behaviours, the provision of such care is consistently reported to be low internationally and in Australia...
June 15, 2017: Trials
https://www.readbyqxmd.com/read/28613395/clozapine-dose-for-schizophrenia
#12
REVIEW
Selvizhi Subramanian, Birgit A Völlm, Nick Huband
BACKGROUND: Schizophrenia and related disorders such as schizophreniform and schizoaffective disorder are serious mental illnesses characterised by profound disruptions in thinking and speech, emotional processes, behaviour and sense of self. Clozapine is useful in the treatment of schizophrenia and related disorders, particularly when other antipsychotic medications have failed. It improves positive symptoms (such as delusions and hallucinations) and negative symptoms (such as withdrawal and poverty of speech)...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28606830/safety-and-tolerability-of-topical-clonazepam-solution-for-management-of-oral-dysesthesia
#13
Michal Kuten-Shorrer, Nathaniel S Treister, Shannon Stock, John M Kelley, Yisi D Ji, Sook-Bin Woo, Mark A Lerman, Stefan Palmason, Stephen T Sonis, Alessandro Villa
OBJECTIVES: The aim of the study was to determine the absolute and relative safety of treatment with 2 concentrations of topical clonazepam solution (0.1 mg/mL, 0.5 mg/mL) for management of oral dysesthesia. STUDY DESIGN: The study was a retrospective chart review of patients diagnosed with oral dysesthesia and managed with topical clonazepam solution (swish and spit) between 2008 and 2015. The relative safety of the 2 concentrations was evaluated in terms of occurrence of adverse drug reactions (ADRs) and occurrence of change to treatment plan secondary to ADRs...
May 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28606772/dominance-status-alters-restraint-induced-neural-activity-in-brain-regions-controlling-stress-vulnerability
#14
Matthew A Cooper, Sahba Seddighi, Abigail K Barnes, J Alex Grizzell, Brooke N Dulka, Catherine T Clinard
Understanding the cellular mechanisms that control resistance and vulnerability to stress is an important step toward identifying novel targets for the prevention and treatment of stress-related mental illness. In Syrian hamsters, dominant and subordinate animals exhibit different behavioral and physiological responses to social defeat stress, with dominants showing stress resistance and subordinates showing stress vulnerability. We previously found that dominant and subordinate hamsters show different levels of defeat-induced neural activity in brain regions that modulate coping with stress, although the extent to which status-dependent differences in stress vulnerability generalize to non-social stressors is unknown...
June 9, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28602015/clinical-and-genetic-analysis-of-indian-patients-with-ndp-related-retinopathies
#15
Dhandayuthapani Sudha, Aparna Ganapathy, Puja Mohan, Ashraf U Mannan, Shuba Krishna, Srividya Neriyanuri, Meenakshi Swaminathan, Pukhraj Rishi, Subbulakshmi Chidambaram, Jayamuruga Pandian Arunachalam
PURPOSE: NDP-related retinopathies are a group of X-linked disorders characterized by degenerative and proliferative changes of the neuroretina, occasionally accompanied with varying degrees of mental retardation and sensorineural hearing loss. NDP is the predominant gene associated with NDP-related retinopathies. The purpose of this study was to report the clinical and genetic findings in three unrelated patients diagnosed with NDP-related retinopathies. METHODS: The patients underwent complete ophthalmic examination followed by genetic analyses...
June 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28601691/effects-of-a-nurse-led-transitional-care-program-on-clinical-outcomes-health-related-knowledge-physical-and-mental-health-status-among-chinese-patients-with-coronary-artery-disease-a-randomized-controlled-trial
#16
Pan Zhang, Yu-Ding Hu, Feng-Mei Xing, Chang-Zai Li, Wang-Feng Lan, Xiao-Li Zhang
BACKGROUND: Coronary artery disease is a major cause of morbidity and mortality among adults worldwide, including China. After a hospital stay, transitional care could help to ensure improved patient care and outcomes, and reduce Medicare costs. Nevertheless, the results of the existing transitional care are not always satisfactory and our knowledge of how to perform effective transitional care for patients with coronary artery disease is limited in mainland China. OBJECTIVES: To examine the effectiveness of a nurse-led transitional care program on clinical outcomes, health-related knowledge, and physical and mental health status among Chinese patients with coronary artery disease...
April 14, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28601504/-changes-in-behaviors-and-indicators-of-mental-health-between-2006%C3%A2-and-2010%C3%A2-in-the-french-working-population
#17
L Malard, J-F Chastang, I Niedhammer
BACKGROUND: The 2008 economic crisis may have had an impact on mental health but the studies on this topic are sparse, in particular among the working population. However, mental health at work is a crucial issue involving substantial costs and consequences. The aim of the study was to assess changes in behaviors and indicators of mental health in the French working population between 2006 and 2010, and to explore the differential changes according to age, origin, occupation, activity sector, public/private sector, self-employed/employee status and work contract...
June 7, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28599166/the-means-side-effect-distinction-in-moral-cognition-a-meta-analysis
#18
Adam Feltz, Joshua May
Experimental research suggests that people draw a moral distinction between bad outcomes brought about as a means versus a side effect (or byproduct). Such findings have informed multiple psychological and philosophical debates about moral cognition, including its computational structure, its sensitivity to the famous Doctrine of Double Effect, its reliability, and its status as a universal and innate mental module akin to universal grammar. But some studies have failed to replicate the means/byproduct effect especially in the absence of other factors, such as personal contact...
June 6, 2017: Cognition
https://www.readbyqxmd.com/read/28597998/a-novel-mechanical-mitral-valve-replacement-using-sapien-xt
#19
Megan Koehle, Justin A Strote, Mark Guadagnoli, J Bradley Oldemeyer
PATIENT PRESENTATION: We report the case of a 66 year old female who presented to our institution fourteen years after receiving a St. Jude Mechanical Mitral Valve Replacement. She presented in refractory NYHA class IV congestive heart failure with comorbidities of acute renal failure, liver failure, and mental status changes. She was found to have immobility of one of the mitral valve disks with resultant severe mitral stenosis with a mean pressure gradient of 12 mmHg. EVALUATION AND MANAGEMENT: The patient was found to have an STS predicted mortality of 39% with redo surgical MVR, and evaluation by the valve team led to a recommendation of a hybrid surgical and transcatheter procedure...
June 9, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28595181/informant-reported-cognitive-decline-and-activity-engagement-across-four-years-in-a-community-sample
#20
Diane E Hosking, Da Jiang, Kerry A Sargent-Cox, Kaarin J Anstey
BACKGROUND: Subtle age-related cognitive decline may be associated with the capacity to remain engaged in mental, physical, and social activities. Informant reports of cognitive decline potentially provide additional information to psychometric tests on change in everyday cognitive function relevant to activity engagement. OBJECTIVE: To investigate relations between decline in everyday cognitive function as assessed by informant report and activity engagement in community-dwelling older adults...
June 9, 2017: Gerontology
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