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Chemotherapy induced thromobocytopenia

Yasuji Komorizono, Kazunori Kohara, Makoto Oketani, Masahiko Maeda, Toshihiko Shibathou, Shuhou Shigenobu, Yasusi Hiramine, Naruhiro Yamasaki, Takushi Arima, Ishibashi Kazuaki, Terukatsu Arima
The purpose of this pilot study was to evaluate the efficacy and adverse events of systemic combined chemotherapy with low dose of 5-fluorouracil (250 mg/m2, 5 days), cisplatin (10 mg/m2, 5 days), and interferon-alpha (2.5 million units, three times weekly) for advanced hepatocellular carcinoma (HCC) underlying liver cirrhosis. Six patients who had advanced HCC with tumor thrombi in the main portal trunk were enrolled in this study. Partial response was achieved in 2, stable disease in 1, and disease progressed in 3...
May 2003: Digestive Diseases and Sciences
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