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Disability assessment

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https://www.readbyqxmd.com/read/28823077/comparison-of-physical-function-in-early-rheumatoid-arthritis-patients-treated-with-biologics-for-1%C3%A2-year-who-achieved-clinical-remission-or-low-disease-activity
#1
Yosuke Hattori, Daihei Kida, Atsushi Kaneko
This study aimed to evaluate whether targeting clinical remission is appropriate for suppressing physical dysfunction in patients with early rheumatoid arthritis (RA). Subjects were all 75 early RA patients (within 2 years of onset) who were continuously treated with biologics for 12 months at our hospital. We evaluated the Simplified Disease Activity Index (SDAI) and Disability Index of the Health Assessment Questionnaire (HAQ-DI) at 3, 6, and 12 months from the initiation of biologics therapy. Rates of functional remission (HAQ-DI ≤ 0...
August 19, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28822922/prevalence-and-socio-demographic-characteristics-of-disability-in-older-adults-in-china-findings-from-china-comprehensive-geriatric-assessment-study
#2
Lina Ma, Zhenzhen Li, Zhe Tang, Fei Sun, Lijun Diao, Jian Li, Yao He, Birong Dong, Yun Li
OBJECTIVE: Disability affects older adults' quality of life. This study aimed to examine the socio-demographic characteristics of disability in older adults in China. METHOD: Data was obtained from the China Comprehensive Geriatric Assessment Study (CCGAS). The sample comprised 6864 people aged 60 years and above from seven provinces in China. A door-to-door survey was conducted by formally trained interviewers using a unified questionnaire. Disability was assessed with physical health assessment comprising activities of daily living (ADL), and independent activities of daily living (IADL)...
August 3, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28822297/validation-of-the-choking-risk-assessment-and-pneumonia-risk-assessment-for-adults-with-intellectual-and-developmental-disability-idd
#3
Justine Joan Sheppard, Georgia A Malandraki, Paula Pifer, Jill Cuff, Michelle Troche, Bronwyn Hemsley, Susan Balandin, Avinash Mishra, Roberta Hochman
BACKGROUND: Risk assessments are needed to identify adults with intellectual and developmental disability (IDD) at high risk of choking and pneumonia. AIM: To describe the development and validation of the Choking Risk Assessment (CRA) and the Pneumonia Risk Assessment (PRA) for adults with IDD. METHODS: Test items were identified through literature review and focus groups. Five-year retrospective chart reviews identified a positive choking group (PCG), a negative choking group (NCG), a positive pneumonia group (PPG), and a negative pneumonia group (NPG)...
August 16, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28821303/validity-and-test-retest-reliability-of-the-self-completion-adult-social-care-outcomes-toolkit-ascot-sct4-with-adults-with-long-term-physical-sensory-and-mental-health-conditions-in-england
#4
Stacey Rand, Juliette Malley, Ann-Marie Towers, Ann Netten, Julien Forder
BACKGROUND: The Adult Social Care Outcomes Toolkit (ASCOT-SCT4) is a multi-attribute utility index designed for the evaluation of long-term social care services. The measure comprises eight attributes that capture aspects of social care-related quality of life. The instrument has previously been validated with a sample of older adults who used home care services in England. This paper aims to demonstrate the instrument's test-retest reliability and provide evidence for its validity in a diverse sample of adults who use publicly-funded, community-based social care in England...
August 18, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28821279/genetic-deletion-of-mglu2-metabotropic-glutamate-receptors-improves-the-short-term-outcome-of-cerebral-transient-focal-ischemia
#5
Federica Mastroiacovo, Slavianka Moyanova, Milena Cannella, Anderson Gaglione, Remy Verhaeghe, Giovanna Bozza, Michele Madonna, Marta Motolese, Anna Traficante, Barbara Riozzi, Valeria Bruno, Giuseppe Battaglia, David Lodge, Ferdinando Nicoletti
We have recently shown that pharmacological blockade of mGlu2 metabotropic glutamate receptors protects vulnerable neurons in the 4-vessel occlusion model of transient global ischemia, whereas receptor activation amplifies neuronal death. This raised the possibility that endogenous activation of mGlu2 receptors contributes to the pathophysiology of ischemic neuronal damage. Here, we examined this possibility using two models of transient focal ischemia: (i) the monofilament model of middle cerebral artery occlusion (MCAO) in mice, and (ii) the model based on intracerebral infusion of endothelin-1 (Et-1) in rats...
August 18, 2017: Molecular Brain
https://www.readbyqxmd.com/read/28821007/measurement-tools-for-mental-health-problems-and-mental-well-being-in-people-with-severe-or-profound-intellectual-disabilities-a-systematic-review
#6
REVIEW
Samantha Flynn, Leen Vereenooghe, Richard P Hastings, Dawn Adams, Sally-Ann Cooper, Nick Gore, Chris Hatton, Kerry Hood, Andrew Jahoda, Peter E Langdon, Rachel McNamara, Chris Oliver, Ashok Roy, Vasiliki Totsika, Jane Waite
Mental health problems affect people with intellectual disabilities (ID) at rates similar to or in excess of the non-ID population. People with severe ID are likely to have persistent mental health problems. In this systematic review (PROSPERO 2015:CRD42015024469), we identify and evaluate the methodological quality of available measures of mental health problems or well-being in individuals with severe or profound ID. Electronic searches of ten databases identified relevant publications. Two reviewers independently reviewed titles and abstracts of retrieved records (n=41,232) and full-text articles (n=573)...
August 11, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28820909/dose-of-physical-activity-physical-functioning-and-disability-risk-in-mobility-limited-older-adults-results-from-the-life-study-randomized-trial
#7
Roger A Fielding, Jack M Guralnik, Abby C King, Marco Pahor, Mary M McDermott, Catrine Tudor-Locke, Todd M Manini, Nancy W Glynn, Anthony P Marsh, Robert S Axtell, Fang-Chi Hsu, W Jack Rejeski
Understanding the minimal dose of physical activity required to achieve improvement in physical functioning and reductions in disability risk is necessary to inform public health recommendations. To examine the effect of physical activity dose on changes in physical functioning and the onset of major mobility disability in The Lifestyle Interventions and Independence for Elders (LIFE) Study. We conducted a multicenter single masked randomized controlled trial that enrolled participants in 2010 and 2011 and followed them for an average of 2...
2017: PloS One
https://www.readbyqxmd.com/read/28820834/super-thin-scip-flap-for-reconstruction-of-subungual-melanoma-aesthetic-functional-surgery
#8
Kyeong-Tae Lee, Bo Young Park, Eun-Ji Kim, Jung-Han Kim, Kee-Taek Jang, Sang-Hee Choi, Dong-Youn Lee, Goo-Hyun Mun
BACKGROUND: This study aimed to use a super-thin, free superficial circumflex iliac artery perforator (SCIP) flap in the functional surgery for treating subungual melanoma and to evaluate its outcomes. METHODS: Forty-one patients with primary subungual melanoma of ≤ 2-mm thickness who were treated with functional surgery were prospectively enrolled. Following oncologic resection, a thin SCIP flap was harvested along the trans-superficial fat layer and transferred to the defect with further thinning by primary defatting...
August 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28820231/interventions-for-treating-persistent-pain-in-survivors-of-torture
#9
REVIEW
Emma Baird, Amanda C de C Williams, Leslie Hearn, Kirstine Amris
BACKGROUND: Persistent (chronic) pain is a frequent complaint in survivors of torture, particularly but not exclusively pain in the musculoskeletal system. Torture survivors may have no access to health care; where they do, they may not be recognised when they present, and the care available often falls short of their needs. There is a tendency in state and non-governmental organisations' services to focus on mental health, with poor understanding of persistent pain, while survivors may have many other legal, welfare, and social problems that take precedence over health care...
August 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28820008/radioscapholunate-fusion-with-triquetrum-and-distal-pole-of-scaphoid-excision-long-term-follow-up
#10
Ngoc B Ha, Joideep Phadnis, Simon B M MacLean, Gregory I Bain
The purpose of this study was to assess the long-term outcomes of radioscapholunate fusion, with and without distal pole of scaphoid excision and excision of the triquetrum. These compromised three operative groups. Seventeen patients were identified with a minimum of 10 years follow-up, with a mean of 15 years (range 10-19). Fifteen of the 17 patients were satisfied with their outcome. Two were converted to total wrist fusion. The mean outcomes scores were; pain visual analogue scale score 2.1/10, Quick Disabilities of the Arm, Shoulder, and Hand 29 and Modified Mayo Wrist score 60...
August 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28819894/cross-cultural-adaptation-and-validation-of-the-dutch-version-of-the-core-outcome-measures-index-for-low-back-pain
#11
J Van Lerbeirghe, J Van Lerbeirghe, P Van Schaeybroeck, H Robijn, R Rasschaert, J Sys, T Parlevliet, G Hallaert, P Van Wambeke, B Depreitere
PURPOSE: The core outcome measures index (COMI) is a validated multidimensional instrument for assessing patient-reported outcome in patients with back problems. The aim of the present study is to translate the COMI into Dutch and validate it for use in native Dutch speakers with low back pain. METHODS: The COMI was translated into Dutch following established guidelines and avoiding region-specific terminology. A total of 89 Dutch-speaking patients with low back pain were recruited from 8 centers, located in the Dutch-speaking part of Belgium...
August 17, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28819125/inflammation-and-bone-mineral-density-a-mendelian-randomization-study
#12
Jian V Huang, C Mary Schooling
Osteoporosis is a common age-related disorder leading to an increase in osteoporotic fractures and resulting in significant suffering and disability. Inflammation may contribute to osteoporosis, as it does to many other chronic diseases. We examined whether inflammation is etiologically relevant to osteoporosis, assessed from bone mineral density (BMD), as a new potential target of intervention, or whether it is a symptom/biomarker of osteoporosis. We obtained genetic predictors of inflammatory markers from genome-wide association studies and applied them to a large genome wide association study of BMD...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819019/retrospectively-assessed-physical-work-environment-during-working-life-and-risk-of-sickness-absence-and-labour-market-exit-among-older-workers
#13
Emil Sundstrup, Åse Marie Hansen, Erik Lykke Mortensen, Otto Melchior Poulsen, Thomas Clausen, Reiner Rugulies, Anne Møller, Lars L Andersen
OBJECTIVE: To determine the prospective association between retrospectively assessed physical work environment during working life and prospectively assessed sickness absence and labour market exit among older workers. METHODS: Using Cox regression analyses we estimated the 4-year to 6-year prospective risk of register-based long-term sickness absence (LTSA), disability pension, early retirement and unemployment from exposure to different physical work environmental factors during working life among 5076 older workers (age 49-63 at baseline) from the Copenhagen Aging and Midlife Biobank cohort...
August 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28818761/the-effect-of-disability-and-depression-on-cognitive-function-and-screening-factors
#14
Chun-Min Chen, Li-Fan Liu
INTRODUCTION: There is increasing evidence that subtle losses in cognitive function may be symptomatic of a transition to early dementia. The objectives of this study were to: 1) test the effect of depressive symptoms and/or disability on cognitive impairment, 2) explore the interaction between depression and disability and the association with cognitive impairment, and 3) evaluate risk factors of health assessment to discriminate between elderly people with or without cognitive impairment...
July 31, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28818714/the-role-of-physical-activity-in-improving-physical-fitness-in-children-with-intellectual-and-developmental-disabilities
#15
Kyla Collins, Kerri Staples
BACKGROUND: One in three children in North America are considered overweight or obese. Children with intellectual and developmental disabilities (IDD) are at an increased risk for obesity than their typically developing peers. Decreased physical activity (PA) and low physical fitness may be contributing factors to this rise in obesity. AIM: Because children with IDD are at an increased risk of diseases related to inactivity, it is important to improve health-related physical fitness to complete activities of daily living and improve health...
August 14, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28818490/inhibition-of-quorum-sensing-controlled-biofilm-formation-in-pseudomonas-aeruginosa-by-quorum-sensing-inhibitors
#16
Kalaiarasan Ellappan, Kottha Thirumalaswamy, Belgode Narasimha Harish, Gnanasambandam Vasuki, Veeresh Kumar Sali, James John
Antimicrobial therapy against extensively drug-resistant (XDR) P. aeruginosa biofilms is less efficient compared to the treatment of equal bacterial counts of free-floating planktonic cells, which has become a serious threat in hospital environment. P. aeruginosa regulate their cooperative activities and physiological process through a cell to cell chemical communication process called Quorum sensing (QS). This attracted our interest to synthesize, and to chemically characterize two anti-QS compounds, N-(4-{4-fluoroanilno} butanoyl) -L-homoserine lactone (FABHL) and N-(4-{4-chlororoanilno} butanoyl) -L-homoserine lactone (CABHL) to inhibit biofilm formation via disabling the QS circuits...
August 14, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28817825/muscle-strength-and-muscle-mass-in-older-patients-during-hospitalization-the-empower-study
#17
Jeanine M Van Ancum, Kira Scheerman, Vincent D Pierik, Siger T Numans, Sjors Verlaan, Hanne E Smeenk, Monique Slee-Valentijn, Roeliene C Kruizinga, Carel G M Meskers, Andrea B Maier
BACKGROUND: Low muscle strength and muscle mass are associated with an increased length of hospital stay and higher mortality rate in inpatients. To what extent hospitalization affects muscle strength and muscle mass is unclear. OBJECTIVE: We aimed to assess muscle strength and muscle mass at admission and during hospitalization in older patients and its relation with being at risk of geriatric conditions. METHODS: The EMPOWER study included patients aged 70 years and older, admitted to 4 wards of the VU University Medical Center in the Netherlands between April and December 2015...
August 18, 2017: Gerontology
https://www.readbyqxmd.com/read/28816915/physician-awareness-of-developmental-screening-and-referral-in-the-state-of-kuwait
#18
Hollie Hix-Small, Khaled Alkherainej
OBJECTIVE: In the State of Kuwait, family physicians and pediatricians are responsible for identifying and referring children at risk of disability. The aims of this study were to better understand physician (1) use of developmental screening instruments, (2) referral practices for children at risk of developmental disability, (3) interpretation of screening results, and (4) anticipatory guidance topics prioritized over child screening. METHODS: A nonprobability volunteer, self-selection sample of family physicians, general practitioners, and pediatricians (n = 398) completed a 60-item paper questionnaire...
August 9, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28816897/surgical-correction-of-cam-deformity-in-association-with-femoroacetabular-impingement-and-its-impact-on-the-degenerative-process-within-the-hip-joint
#19
Paul E Beaulé, Andrew D Speirs, Helen Anwander, Gerd Melkus, Kawan Rakhra, Hanspeter Frei, Mario Lamontagne
BACKGROUND: Cam morphology in association with femoroacetabular impingement (FAI) is a recognized cause of hip pain and cartilage damage and proposed as a leading cause of arthritis. The purpose of this study was to analyze the functional and biomechanical effects of the surgical correction of the cam deformity on the degenerative process associated with FAI. METHODS: Ten male patients with a mean age of 34.3 years (range, 23.1 to 46.5 years) and a mean body mass index (and standard deviation) of 26...
August 16, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28816869/spine-trauma-what-are-the-current-controversies
#20
Cumhur Oner, Shanmuganathan Rajasekaran, Jens R Chapman, Michael G Fehlings, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, James Harrop
Although less common than other musculoskeletal injuries, spinal trauma may lead to significantly more disability and costs. During the last 2 decades there was substantial improvement in our understanding of the basic patterns of spinal fractures leading to more reliable classification and injury severity assessment systems but also rapid developments in surgical techniques. Despite these advancements, there remain unresolved issues concerning the management of these injuries. At this moment there is persistent controversy within the spinal trauma community, which can be grouped under 6 headings...
September 2017: Journal of Orthopaedic Trauma
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