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https://www.readbyqxmd.com/read/28721306/role-of-conventional-magnetic-resonance-imaging-in-the-screening-of-epilepsy-with-structural-abnormalities-a-pictorial-essay
#1
REVIEW
Xu Zhao, Zhiqiang Zhou, Wenzhen Zhu, Hongbing Xiang
Epilepsy is a chronic neurological disease with serious impact on patients and society. The causes of epilepsy comprise a heterogeneous group of disorders, rendering epilepsy diagnoses rather difficult and challenging. The primary role of MRI is to locate and define the probable anatomic epileptogenic lesions. In the developing countries, where functional MRI (fMRI) is not popular, conventional MRI (cMRI) becomes especially important in epilepsy diagnoses. Apart from that, an experienced radiologist can increase the diagnostic yield of MRI to epileptogenic lesions...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28710601/the-effects-of-collective-and-personal-transitions-on-the-organization-and-contents-of-autobiographical-memory-in-older-chinese-adults
#2
Xuan Gu, Chi-Shing Tse, Norman R Brown
Life transitions like war, marriage, and immigration presumably organize autobiographical memory. Yet little is known about how the magnitude of a given transition affects this mnemonic impact. To examine this issue, we collected (a) word-cued events, (b) event-dating protocols, (c) personally important events, and (d) transitional impact scores of the Cultural Revolution (1966-1976) and important events from Chinese adults who had been adolescents during the revolution. There were three main findings. First, rusticated participants, who moved from cities to rural areas during the Cultural Revolution, dated autobiographical memories in relation to this collective transition more frequently than nonrusticated participants, with the former group reporting a greater material (but not psychological) change in their lives due to this collective transition than the latter group...
July 14, 2017: Memory & Cognition
https://www.readbyqxmd.com/read/28698596/aerobic-fitness-associates-with-mnemonic-discrimination-as-a-mediator-of-physical-activity-effects-evidence-for-memory-flexibility-in-young-adults
#3
Kazuya Suwabe, Kazuki Hyodo, Kyeongho Byun, Genta Ochi, Takemune Fukuie, Takeshi Shimizu, Morimasa Kato, Michael A Yassa, Hideaki Soya
A physically active lifestyle has beneficial effects on hippocampal memory function. A potential mechanism for this effect is exercise-enhanced hippocampal plasticity, particularly in the dentate gyrus (DG). Within hippocampal memory formation, the DG plays a crucial role in pattern separation, which is the ability to discriminate among similar experiences. Computational models propose a theoretical hypothesis that enhanced DG-mediated pattern separation leads to "memory flexibility"-a selective improvement in the ability to overcome moderate levels of mnemonic interference...
July 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28697639/forgetting-and-emotion-regulation-in-mental-health-anxiety-and-depression
#4
Simon Nørby
Does normal forgetting facilitate mental health and is forgetting impaired in affective disorders? This double-sided question may seem counterintuitive given the fact that forgetting is often associated with troubles in everyday life. However, forgetting does not only have destructive consequences, but also fulfils important functions. I consider the possibility that forgetting may function as a beneficial sorting mechanism which helps healthy people discard information that is undesirable and unpleasant. Thus, selective forgetting of negative memories may be part of emotion regulation, that is, people's attempts to control when and how they experience and express emotions...
July 12, 2017: Memory
https://www.readbyqxmd.com/read/28697376/erps-and-oscillations-during-encoding-predict-retrieval-of-digit-memory-in-superior-mnemonists
#5
Yafeng Pan, Xianchun Li, Xi Chen, Yixuan Ku, Yujie Dong, Zheng Dou, Lin He, Yi Hu, Weidong Li, Xiaolin Zhou
Previous studies have consistently demonstrated that superior mnemonists (SMs) outperform normal individuals in domain-specific memory tasks. However, the neural correlates of memory-related processes remain unclear. In the current EEG study, SMs and control participants performed a digit memory task during which their brain activity was recorded. Chinese SMs used a digit-image mnemonic for encoding digits, in which they associated 2-digit groups with images immediately after the presentation of each even-position digit in sequences...
July 8, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28694097/behavioural-pharmacology-of-the-%C3%AE-5-gabaa-receptor-antagonist-s44819-enhancement-and-remediation-of-cognitive-performance-in-preclinical-models
#6
István Gacsályi, Krisztina Móricz, Gábor Gigler, János Wellmann, Katalin Nagy, István Ling, József Barkóczy, József Haller, Jeremy J Lambert, Gábor Szénási, Michael Spedding, Ferenc A Antoni
Previous work has shown that S44819 is a novel GABAA receptor (GABAAR) antagonist, which is selective for extrasynaptic GABAARs incorporating the α5 subunit (α5-GABAARs). The present study reports on the preclinical neuropsychopharmacological profile of S44819. Significantly, no sedative or pro-convulsive side effects of S44819 were found at doses up to 30 mg/kg i.p. Object recognition (OR) memory in intact mice was enhanced by S44819 (0.3 mg/kg p.o.) given before the acquisition trial. Mice treated with phencyclidine for two weeks and tested six days after the cessation of treatment failed to show OR memory...
July 8, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28692355/teaching-clinical-reasoning-to-medical-students
#7
Lisa Amey, Kenneth J Donald, Andrew Teodorczuk
Clinical reasoning is often not explicitly addressed in the early medical school curriculum. As a result, students observe the process while on clinical placements with little or no understanding of the complex processes underlying it. Clinical reasoning has significant implications for patient safety. Medical errors as a consequence of faulty reasoning contribute to patient morbidity and mortality. Educating medical students at an early stage about the processes of clinical reasoning and strategies to avoid associated errors can have positive impacts upon patient safety...
July 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28691973/a-swift-method-for-handing-off-obstetrical-patients-on-the-labor-floor
#8
Jean-Ju Sheen, Laura Reimers, Shravya Govindappagari, Ivan M Ngai, Diana Garretto, Roopali Donepudi, Pamela Tropper, Dena Goffman, Ashlesha K Dayal, Peter S Bernstein
OBJECTIVE: The aim of this study was to improve patient handoffs on the labor floor. METHODS: A prospective cohort study of obstetrics residents at Montefiore Medical Center was performed between 2012 and 2014. Labor-floor handoffs were recorded before and after didactic sessions as well as after installation of whiteboards formatted with the mnemonic SWIFT (Subject, Why?, Issues, Fetus, Tasks). Handoff transcripts were evaluated by obstetricians blinded to timing and speaker identity...
July 6, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28690433/recognition-without-words-using-taste-to-explore-survival-processing
#9
Henry L Hallock, Heather D Garman, Shaun P Cook, Shawn P Gallagher
Many educational demonstrations of memory and recall employ word lists and number strings; items that lend themselves to semantic organization and "chunking." By applying taste recall to the adaptive memory paradigm, which evaluates memory from a survival-based evolutionary perspective, we have developed a simple, inexpensive exercise that defies mnemonic strategies. Most adaptive memory studies have evaluated recall of words encountered while imagining survival and non-survival scenarios. Here, we've left the lexical domain and hypothesized that taste memory, as measured by recognition, would be best when acquisition occurs under imagined threat of personal harm, namely poisoning...
2017: Journal of Undergraduate Neuroscience Education: JUNE: a Publication of FUN, Faculty for Undergraduate Neuroscience
https://www.readbyqxmd.com/read/28688871/the-lateral-habenula-and-adaptive-behaviors
#10
REVIEW
Sheri J Y Mizumori, Phillip M Baker
The evolutionarily conserved lateral habenula (LHb) enables dynamic responses to continually changing contexts and environmental conditions. A model is proposed to account for greater mnemonic and contextual control over LHb-mediated response flexibility as vertebrate brains became more complex. The medial prefrontal cortex (mPFC) provides instructions for context-specific responses to LHb, which assesses the extent to which this response information matches the motivation or internal state of the individual...
July 5, 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/28686560/-hoarding-disorder-in-dsm-5-clinical-description-and-cognitive-approach
#11
L Kalogeraki, I Michopoulos
Hoarding disorder is characterized by difficulty discarding or parting with possessions regardless their actual value as well as, in most cases, persistent acquisition of objects. Possessions are accumulated in large numbers that fill up and clutter active living space to the extent that its intended use is no longer possible resulting to significant functional impairment and/or distress. Saving and difficulty discarding appear to be associated to subjective beliefs about the instrumental, sentimental or intrinsic value of objects...
April 2017: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28684734/spatiotemporal-neural-characterization-of-prediction-error-valence-and-surprise-during-reward-learning-in-humans
#12
Elsa Fouragnan, Filippo Queirazza, Chris Retzler, Karen J Mullinger, Marios G Philiastides
Reward learning depends on accurate reward associations with potential choices. These associations can be attained with reinforcement learning mechanisms using a reward prediction error (RPE) signal (the difference between actual and expected rewards) for updating future reward expectations. Despite an extensive body of literature on the influence of RPE on learning, little has been done to investigate the potentially separate contributions of RPE valence (positive or negative) and surprise (absolute degree of deviation from expectations)...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28679836/effects-of-the-i-pass-nursing-handoff-bundle-on-communication-quality-and-workflow
#13
Amy J Starmer, Kumiko O Schnock, Aimee Lyons, Rebecca S Hehn, Dionne A Graham, Carol Keohane, Christopher P Landrigan
BACKGROUND AND OBJECTIVE: Handoff communication errors are a leading source of sentinel events. We sought to determine the impact of a handoff improvement programme for nurses. METHODS: We conducted a prospective pre-post intervention study on a paediatric intensive care unit in 2011-2012. The I-PASS Nursing Handoff Bundle intervention consisted of educational training, verbal handoff I-PASS mnemonic implementation, and visual materials to provide reinforcement and sustainability...
July 5, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28673769/age-related-deficits-in-the-mnemonic-similarity-task-for-objects-and-scenes
#14
Shauna M Stark, Craig E L Stark
Using the Mnemonic Similarity Task (MST), we have demonstrated an age-related impairment in lure discrimination, or the ability to recognize an item as distinct from one that was similar, but not identical to one viewed earlier. A growing body of evidence links these behavioral changes to age-related alterations in the hippocampus. In this study, we sought to evaluate a novel version of this task, utilizing scenes that might emphasize the role of the hippocampus in contextual and spatial processing. In addition, we investigated whether, by utilizing two stimulus classes (scenes and objects), we could also interrogate the roles of the PRC and PHC in aging...
July 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28671972/diaphragm-a-mnemonic-to-describe-the-work-of-breathing-in-patients-with-respiratory-failure
#15
Aiman Tulaimat, William E Trick
BACKGROUND: The assessment of the work of breathing in the definitions of respiratory failure is vague and variable. OBJECTIVE: Identify a parsimonious set of signs to describe the work of breathing in hypoxemic, acutely ill patients. METHODS: We examined consecutive medical ICU patients receiving oxygen with a mask, non-invasive ventilation, or T-piece. A physician inspected each patient for 10 seconds, rated the level of respiratory distress, and then examined the patient for vital signs and 17 other physical signs...
2017: PloS One
https://www.readbyqxmd.com/read/28670293/rapid-estimation-of-gustatory-sensitivity-thresholds-with-siam-and-quest
#16
Richard Höchenberger, Kathrin Ohla
Adaptive methods provide quick and reliable estimates of sensory sensitivity. Yet, these procedures are typically developed for and applied to the non-chemical senses only, i.e., to vision, audition, and somatosensation. The relatively long inter-stimulus-intervals in gustatory studies, which are required to minimize adaptation and habituation, call for time-efficient threshold estimations. We therefore tested the suitability of two adaptive yes-no methods based on SIAM and QUEST for rapid estimation of taste sensitivity by comparing test-retest reliability for sucrose, citric acid, sodium chloride, and quinine hydrochloride thresholds...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28669783/gabaergic-signaling-within-the-basolateral-amygdala-complex-modulates-resistance-to-the-labilization-reconsolidation-process
#17
Pablo Javier Espejo, Pharm D Vanesa Ortiz, Irene Delia Martijena, Victor Alejandro Molina
It is well known that stress can affect mnemonic processes. In particular, stress before contextual fear conditioning induces a memory which exhibits resistance to being interfered with by Midazolam (MDZ) when applied after memory retrieval. Moreover, stress exposure strongly affects GABAergic transmission within the Basolateral Amygdala Complex (BLA), a brain structure critically involved in fear memory processing. The present study evaluated the involvement of GABAergic signaling within the BLA on the induction of resistance to memory reconsolidation interference...
June 29, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28669115/rats-know-when-they-remember-transfer-of-metacognitive-responding-across-odor-based-delayed-match-to-sample-tests
#18
Victoria L Templer, Keith A Lee, Aidan J Preston
Metamemory entails cognitively assessing the strength of one's memories. We tested the ability of nine Long-Evans rats to distinguish between remembering and forgetting by presenting a decline option that allowed a four-choice odor-based delayed match to sample (DMTS) tests to be by-passed. Rats performed significantly better on tests they chose to take than on tests they were forced to take, indicating metacognitive responding. However, rather than control by internal mnemonic cues, one alternative explanation is that decline use is based on external test-specific cues that become associated with increased rewards overtime...
July 1, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28661223/when-lying-changes-memory-for-the-truth
#19
Henry Otgaar, Alysha Baker
In the legal field, victims and offenders frequently lie to avoid talking about serious incidents, such as past experiences of sexual abuse or criminal involvement. Although these individuals may initially lie about an experienced event, oftentimes these same people eventually abandon their lies and are forthcoming with what truly happened. To date, it is unclear whether such lying affects later statements about one's memory for the experienced event. The impetus of the present review is to compile the current state of knowledge on the effects of lying on memory...
June 22, 2017: Memory
https://www.readbyqxmd.com/read/28657557/enhancing-student-empathetic-engagement-history-taking-and-communication-skills-during-electronic-medical-record-use-in-patient-care
#20
Alisa Alfonsi LoSasso, Courtney E Lamberton, Mary Sammon, Katherine T Berg, John W Caruso, Jonathan Cass, Mohammadreza Hojat
PURPOSE: To examine whether an intervention on proper use of electronic medical records (EMRs) in patient care could help improve medical students' empathic engagement, and to test the hypothesis that the training would reduce communication hurdles in clinical encounters. METHOD: Seventy third-year medical students from the Sidney Kimmel Medical College at Thomas Jefferson University were randomly divided into intervention and control groups during their six-week pediatric clerkship in 2012-2013...
July 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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