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https://www.readbyqxmd.com/read/28213925/rotator-cuff-disease-opinion-regarding-surgical-criteria-and-likely-outcome
#1
Alison Thorpe, Mark Hurworth, Peter O'Sullivan, Tim Mitchell, Anne Smith
BACKGROUND: Clinical guidelines for the management of rotator cuff disease are not clear. Surgeon surveys in the USA and UK lack agreement regarding surgical indications. Physical examination tests aid surgical decision-making but also lack robust evidence. Study aims were to evaluate: Western Australian orthopaedic surgeons' perceptions about surgical indications; utility of physical examination tests; findings at surgery predictive of outcome and surgeon opinion of a successful surgical outcome...
February 17, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28213765/association-between-signs-and-symptoms-of-bruxism-and-presence-of-tori-a-systematic-review
#2
Eduardo Bertazzo-Silveira, Juliana Stuginski-Barbosa, André Luís Porporatti, Bruce Dick, Carlos Flores-Mir, Daniele Manfredini, Graziela De Luca Canto
OBJECTIVE: This systematic review aims to answer the question: "Is there an association between any specific signs and symptoms of bruxism and the presence of tori?" MATERIAL AND METHODS: Observational studies, which evaluated the association between signs and symptoms of bruxism and tori, were selected. Signs and symptoms of bruxism (such as teeth grinding, jaw clenching, abnormal tooth wear, facial muscle hypertrophy, pain, or fatigue) had to be determined by questionnaire or anamnesis and tori within clinical assessment...
February 17, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28212122/a-research-of-soft-tissue-lipoma-genesis-factor-with-immunohistochemical-analysis
#3
Jun Beom Lee, Hwan Jun Choi, Eun Taik Son, Jun Hyuk Kim
INTRODUCTION: Lipoma is the most familiar soft-tissue tumor. But the etiology of lipoma remains imprecise. Sex steroid hormones such as estrogen have effects on muscle and adipose tissue development. There is now significant evidence that sex steroids are involved in the site specificities of adipose tissue metabolism. This association of adipose tissue metabolism between sex steroid hormones suggests a possible role for sex steroids in the pathogenesis of lipoma. METHODS: To investigate this concept, the authors evaluated the expression of the estrogen receptor (ER) and the progesterone receptor (PR) in soft tissue lipoma in this study...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28212118/role-of-chronic-exercise-on-pelvic-floor-support-and-function
#4
Janet M Shaw, Ingrid E Nygaard
PURPOSE OF REVIEW: To summarize recent literature about the potential role of chronic exercise on pelvic floor support and function. RECENT FINDINGS: Stress urinary incontinence is common during physical activity. Scant evidence suggests a dose-response association between higher volumes of exercise and urinary incontinence. Athletes do not appear to have greater pelvic floor muscle strength or worse pelvic floor support compared to nonathletes. Pelvic floor muscle electromyographic activity increases substantially as running speeds increase...
February 16, 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28210047/the-effect-of-visual-field-condition-on-kinetic-in-upper-extremities-and-e-m-g-in-lower-extremities-while-performing-reaching-in-normal-adults
#5
Hyekang Park, Youngeun Kang, Minah Yoo, Bomjin Lee, Jeongok Yang, Joongsook Lee, Dongwook Han, Taeyoung Oh
[Purpose] The aims of this study was to investigate mean velocity and angle of shoulder joint, activation of tibialis anterior and gastrocnemius according to both eyes, dominant eye and non-dominant eye condition during reaching task in normal adults. [Subjects and Methods] Our research recruited 24 participants (male 11, female 13) in Silla University. Participants were performed reaching out movement by conditions of both eye, dominants eye, non-dominants eye. The target was placed at 45 degree diagonal direction and distance far away 130% of their arm length...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28207424/skeletal-muscle-wasting-new-role-of-nonclassical-renin-angiotensin-system
#6
Claudio Cabello-Verrugio, Juan C Rivera, Dominga Garcia
PURPOSE OF REVIEW: Skeletal muscle can be affected by many physiological and pathological conditions that contribute to the development of muscle weakness, including skeletal muscle loss, inflammatory processes, or fibrosis. Therefore, research into therapeutic treatment alternatives or alleviation of these effects on skeletal muscle is of great importance. RECENT FINDINGS: Recent studies have shown that angiotensin (1-7) [Ang-(1-7)] - a vasoactive peptide of the nonclassical axis in the renin-angiotensin system (RAS) - and its Mas receptor are expressed in skeletal muscle...
February 16, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28206796/affect-from-mere-perception-illusory-contour-perception-feels-good
#7
Thorsten M Erle, Rolf Reber, Sascha Topolinski
Can affect be evoked by mere perception? Earlier work on processing fluency, which manipulated the dynamics of a running perceptual process, has shown that efficient processing can indeed trigger positive affect. The present work introduces a novel route by not manipulating the dynamics of an ongoing perceptual process, but by blocking or allowing the whole process in the first place. We used illusory contour perception as one very basic such process. In 5 experiments (total N = 422), participants briefly (≤100 ms) viewed stimuli that either allowed illusory contour perception, so-called Kanizsa shapes, or proximally identical control shapes that did not allow for this process to occur...
February 16, 2017: Emotion
https://www.readbyqxmd.com/read/28205203/effects-of-different-types-of-exercise-on-body-composition-muscle-strength-and-igf-1-in-the-elderly-with-sarcopenic-obesity
#8
Hung-Ting Chen, Yu-Chun Chung, Yu-Jen Chen, Sung-Yen Ho, Huey-June Wu
OBJECTIVES: To investigate the influence of resistance training (RT), aerobic training (AT), or combination training (CT) interventions on the body composition, muscle strength performance, and insulin-like growth factor 1 (IGF-1) of patients with sarcopenic obesity. DESIGN: Randomized controlled trial. SETTING: Community center and research center. PARTICIPANTS: Sixty men and women aged 65-75 with sarcopenic obesity...
February 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28204905/transcriptome-assembly-and-identification-of-genes-and-snps-associated-with-growth-traits-in-largemouth-bass-micropterus-salmoides
#9
Shengjie Li, Hao Liu, Junjie Bai, Xinping Zhu
Growth is one of the most crucial economic traits of all aquaculture species, but the molecular mechanisms involved in growth of largemouth bass (Micropterus salmoides) are poorly understood. The objective of this study was to screen growth-related genes of M. salmoides by RNA sequencing and identify growth-related single-nucleotide polymorphism (SNP) markers through a growth association study. The muscle transcriptomes of fast- and slow-growing largemouth bass were obtained using the RNA-Seq technique. A total of 54,058,178 and 54,742,444 qualified Illumina read pairs were obtained for the fast-growing and slow-growing groups, respectively, giving rise to 4,865,236,020 and 4,926,819,960 total clean bases, respectively...
February 15, 2017: Genetica
https://www.readbyqxmd.com/read/28203388/on-the-development-of-the-chondrocranium-and-the-histological-anatomy-of-the-head-in-perinatal-stages-of-marsupial-mammals
#10
REVIEW
Marcelo R Sánchez-Villagra, Analía M Forasiepi
An overview of the literature on the chondrocranium of marsupial mammals reveals a relative conservatism in shape and structures. We document the histological cranial anatomy of individuals representing Monodelphis domestica, Dromiciops gliroides, Perameles sp. and Macropus eugenii. The marsupial chondrocranium is generally characterized by the great breadth of the lamina basalis, absence of pila metoptica and large otic capsules. Its most anterior portion (cupula nasi anterior) is robust, and anterior to it there are well-developed tactile sensory structures, functionally important in the neonate...
2017: Zoological Letters
https://www.readbyqxmd.com/read/28203223/impaired-axonal-regeneration-in-diabetes-perspective-on-the-underlying-mechanism-from-in-vivo-and-in-vitro-experimental-studies
#11
REVIEW
Kazunori Sango, Hiroki Mizukami, Hidenori Horie, Soroku Yagihashi
Axonal regeneration after peripheral nerve injury is impaired in diabetes, but its precise mechanisms have not been elucidated. In this paper, we summarize the progress of research on altered axonal regeneration in animal models of diabetes and cultured nerve tissues exposed to hyperglycemia. Impaired nerve regeneration in animal diabetes can be attributed to dysfunction of neurons and Schwann cells, unfavorable stromal environment supportive of regenerating axons, and alterations of target tissues receptive to reinnervation...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28202739/anti-hmgcr-autoantibodies-in-juvenile-idiopathic-inflammatory-myopathies-identify-a-rare-but-clinically-important-subset-of-patients
#12
Sarah L Tansley, Zoe E Betteridge, Stefania Simou, Thomas S Jacques, Clarissa Pilkington, Mark Wood, Kishore Warrier, Lucy R Wedderburn, Neil J McHugh
OBJECTIVE: We aimed to establish the prevalence and clinical associations of anti-HMG-CoA-reductase (anti-HMGCR) in a large UK cohort with juvenile myositis. METHODS: There were 381 patients investigated for anti-HMGCR using ELISA. RESULTS: Anti-HMGCR autoantibodies were detected in 4 patients (1%). These children had no or minimal rash and significant muscle disease. Muscle biopsies were considered distinctive, with widespread variation in fiber size, necrotic fibers, and chronic inflammatory cell infiltrates; all had prolonged elevation of creatine kinase and all ultimately received biologic therapies...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28202235/stx12-lncrna-mir-148a-smad5-participate-in-the-regulation-of-pancreatic-stellate-cell-activation-through-a-mechanism-involving-competing-endogenous-rna
#13
Hao Wang, Yanfeng Jiang, Ming Lu, Bei Sun, Xin Qiao, Dongbo Xue, Weihui Zhang
BACKGROUND: With the deepening of research, the roles of LncRNAs play in the fibrotic process have attracted great attention. At the early stage of pancreatic fibrogenesis, to effectively regulate pancreatic stellate cells (PSCs) activation is crucial for the treatment of chronic pancreatic fibrosis. METHODS: Microarray data on chronic pancreatitis were retrieved from the Gene Expression Omnibus (GEO) repository and analyzed using bioinformatic methods. A diagram of the lncRNA-miRNA-mRNA ceRNA network was constructed...
February 1, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28198733/clinical-relevance-of-sarcopenia-in-chronic-kidney-disease
#14
Ranjani N Moorthi, Keith G Avin
PURPOSE OF REVIEW: In this article, we review sarcopenia in chronic kidney disease (CKD). We aim to present how definitions of sarcopenia from the general population may pertain to those with CKD, its assessment by clinicians and emerging therapies for sarcopenia in CKD. For this review, we limit our description and recommendations to patients with CKD who are not on dialysis. RECENT FINDINGS: Poorer parameters of lean mass, strength and physical function are associated with worsening patient-centered outcomes such as limiting mobility, falls and mortality in CKD; however, the magnitude of these associations are different in those with and without CKD...
February 13, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28198602/the-profile-of-upper-extremity-muscular-strength-in-female-wheelchair-basketball-players-a-pilot-study
#15
Bahar Külünkoğlu, Yasemin Akkubak, Nevin Ergun
BACKGROUND: The purpose of this study was to analyze and compare the profile of upper extremity muscle strength in female wheelchair basketball players with that of sex-matched non-disabled controls. METHODS: Nineteen female subjects were enrolled in this study. These were divided into two groups. Group 1 (n=10) consisted of wheelchair basketball players and Group 2 (n=9) of non-disabled individuals. Muscular strength in the shoulder was measured using an isokinetic dynamometer...
February 14, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28198139/peptidomics-analysis-of-transient-regeneration-in-the-neonatal-mouse-heart
#16
Yi Fan, Qijun Zhang, Hua Li, Zijie Cheng, Xing Li, Yumei Chen, Yahui Shen, Guixian Song, Lingmei Qian
Neonatal mouse hearts have completely regenerative capability after birth, but the ability to regenerate rapidly lost after 7 days, the mechanism has not been clarified. Previous studies have shown that mRNA profile of adult mouse changed greatly compared to neonatal mouse. So far, there is no research of peptidomics related to heart regeneration. In order to explore the changes of proteins, enzymes and peptides related to the transient regeneration, we used comparative petidomics technique to compare the endogenous peptides in the mouse heart of postnatal 1 and 7 days...
February 15, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28197667/discovery-and-progress-of-direct-cardiac-reprogramming
#17
REVIEW
Hidenori Kojima, Masaki Ieda
Cardiac disease remains a major cause of death worldwide. Direct cardiac reprogramming has emerged as a promising approach for cardiac regenerative therapy. After the discovery of MyoD, a master regulator for skeletal muscle, other single cardiac reprogramming factors (master regulators) have been sought. Discovery of cardiac reprogramming factors was inspired by the finding that multiple, but not single, transcription factors were needed to generate induced pluripotent stem cells (iPSCs) from fibroblasts. We first reported a combination of cardiac-specific transcription factors, Gata4, Mef2c, and Tbx5 (GMT), that could convert mouse fibroblasts into cardiomyocyte-like cells, which were designated as induced cardiomyocyte-like cells (iCMs)...
February 14, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28195249/building-blocks-of-the-gipu-italian-group-of-ultrastructural-pathology
#18
V Papa, R Costa, G Cenacchi
The Italian Group of Ultrastructural Pathology, GIPU, is a scientific organization committed to promote the art and science of Electron Microscopy (EM) in the pathology field in Italy, sharing its professional work with a public audience. The history of the GIPU goes back to 1990s when a founder group set up the Italian Group of Ultrastructural Diagnostic (GIDU) in Milan. The central focus of annual meetings was on EM, transmission and scanning one, about interesting cases in which it was instrumental in diagnosis...
June 2016: Pathologica
https://www.readbyqxmd.com/read/28195225/a-novel-bk-channel-targeted-peptide-suppresses-sound-evoked-activity-in-the-mouse-inferior-colliculus
#19
L L Scott, E J Brecht, A Philpo, S Iyer, N S Wu, S J Mihic, R W Aldrich, J Pierce, J P Walton
Large conductance calcium-activated (BK) channels are broadly expressed in neurons and muscle where they modulate cellular activity. Decades of research support an interest in pharmaceutical applications for modulating BK channel function. Here we report a novel BK channel-targeted peptide with functional activity in vitro and in vivo. This 9-amino acid peptide, LS3, has a unique action, suppressing channel gating rather than blocking the pore of heterologously expressed human BK channels. With an IC50 in the high picomolar range, the apparent affinity is higher than known high affinity BK channel toxins...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28194410/acute-feasibility-of-neuromuscular-electrical-stimulation-in-severely-obese-patients-with-obstructive-sleep-apnea-syndrome-a-pilot-study
#20
RANDOMIZED CONTROLLED TRIAL
Isabelle Vivodtzev, Nicola A Maffiuletti, Anne-Laure Borel, Angélique Grangier, Bernard Wuyam, Renaud Tamisier, Jean-Louis Pépin
Objective. Obesity and obstructive sleep apnea (OSA) are closely interconnected conditions both leading to high cardiovascular risk. Inactivity is frequent and physical activity programs remain difficult in these patients. We investigated the acute feasibility of two neuromuscular electrical stimulation (NMES) modalities in extremely inactive obese patients with OSA. Design. A randomized cross-over study, with two experimental sessions (one per condition: multipath NMES versus conventional NMES). Setting. Outpatient research hospital...
2017: BioMed Research International
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