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https://www.readbyqxmd.com/read/27911231/systematic-review-of-ventricular-peritoneal-shunt-and-percutaneous-endoscopic-gastrostomy-a-safe-combination
#1
Leendert H Oterdoom, D L Marinus Oterdoom, Johannes C F Ket, J Marc C van Dijk, Pieter Scholten
OBJECTIVE Various international and national gastrointestinal guidelines take different positions on whether ventriculoperitoneal shunt (VPS) insertion is a contraindication to percutaneous endoscopic gastrostomy (PEG). The objective of this meta-analysis was to try to answer the question of whether VPS insertion is a contraindication to PEG. METHODS A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Electronic databases PubMed and Embase were searched using variations of the terms "ventriculo-peritoneal shunt" and "percutaneous (endoscopic) gastrostomy...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27902596/portable-disposable-ultrathin-endoscopy-tested-through-percutaneous-endoscopic-gastrostomy
#2
Myong Ki Baeg, Chul-Hyun Lim, Jin Su Kim, Yu Kyung Cho, Jae Myung Park, Bo-In Lee, In-Seok Lee, Myung-Gyu Choi
BACKGROUND: A portable disposable ultrathin endoscope (DUE) with high visual quality and maneuverability would reduce the need for expensive facilities and emergency endoscopy could be available anywhere. It would increase patient satisfaction, prevent unnecessary sedation, and reduce infection. Our aim was to evaluate the usefulness of portable DUE in performing percutaneous endoscopic gastrostomy (PEG). METHODS: We prospectively enrolled patients who underwent PEG under DUE guidance and compared them with historical controls who underwent PEG under conventional ultrathin endoscopy (CUE) guidance...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27891266/a-silent-and-chronic-complication-of-percutaneous-endoscopic-gastrostomy-tube-small-bowel-enterocutaneous-fistula
#3
Sai Wah Cheung
Percutaneous endoscopic gastrostomy (PEG) has gradually gained the popularity since its invention and become the most preferred method for gastrostomy insertion in recent years. PEG is associated with lower morbidity and mortality and has the advantages of being minimally invasive and more convenient over the conventional open gastrostomy. However, significant rates of major complication still occur. Enterocutaneous fistula is one of the key complications that can be easily neglected due to its asymptomatic nature...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27876446/gastrostomy-tube-placement-is-safe-in-advanced-amyotrophic-lateral-sclerosis
#4
Manisha Kak, Naoum P Issa, Raymond P Roos, Bobbie Jean Sweitzer, Ori Gottlieb, Amy Guralnick, Steven R White, Carol E Semrad, Betty Soliven, Joumana Baroody, Kourosh Rezania
OBJECTIVES: To evaluate the safety and effect on survival of insertion of a gastrostomy tube (G-tube) in patients with amyotrophic lateral sclerosis (ALS) who have upright forced vital capacity (uFVC) ≤ 50% predicted. Current guidelines, which are based on higher rates of post-procedure complications in ALS patients with advanced respiratory dysfunction, have led to a recommendation to perform G-tube insertion before the FVC drops to <50% predicted, even when the patient has no significant dysphagia...
November 23, 2016: Neurological Research
https://www.readbyqxmd.com/read/27856367/dysphagia-is-prevalent-in-patients-with-cpeo-and-single-large-scale-deletions-in-mtdna
#5
Gitte Hedermann, Nicoline Løkken, Julia R Dahlqvist, John Vissing
BACKGROUND: The aim of this study was to assess the frequency of subjective and objective dysphagia in patients with chronic progressive external ophthalmoplegia (CPEO) due to single, large-scale deletions (LSDs) of mitochondrial DNA (mtDNA). METHODS: Sixteen patients with CPEO and single LSDs of mtDNA were included in the study and compared to a control group of 12 patients with the m.3243A>G mtDNA mutation. Patients had to drink 80ml of water at 4°C as fast as they could (cold-water test) and fill out a standardized questionnaire about dysphagia...
November 14, 2016: Mitochondrion
https://www.readbyqxmd.com/read/27853378/benefit-of-percutaneous-endoscopic-gastrostomy-in-patients-undergoing-definitive-chemoradiotherapy-for-locally-advanced-nasopharyngeal-carcinoma
#6
Yun Xu, Qiaojuan Guo, Jin Lin, Bijuan Chen, Jiangmei Wen, Tianzhu Lu, Yuanji Xu, Mingwei Zhang, Jianji Pan, Shaojun Lin
BACKGROUND AND AIM: To evaluate the impact of percutaneous endoscopic gastrostomy (PEG) tube on nutritional status, treatment-related toxicity, and treatment tolerance in patients with locally advanced nasopharyngeal carcinoma (NPC) who underwent chemoradiotherapy. PATIENTS AND METHODS: We enrolled 133 consecutive non-metastatic NPC (III/IV stage) patients, who were treated with prophylactic PEG feeding before the initiation of concurrent chemoradiotherapy (CCRT) between June 1, 2010 and June 30, 2014...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27847836/obstructive-acute-pancreatitis-secondary-to-peg-tube-migration
#7
Douglas F Taylor, Ryan Cho, Allan Cho, Viet Nguyen, Abhijit Sunnapwar, Craig Womeldorph
Percutaneous gastrostomy is a well-established method of providing enteral nutrition to patients incapable of oral intake, or for whom oral intake is insufficient to meet metabolic needs. In comparison to total parenteral nutrition, enteral feeding is advantageous in that it helps maintain gut mucosal integrity, which decreases the risk of bacterial translocation through the gastrointestinal tract. Complications include bleeding, aspiration, internal organ injury, perforation, periostomal leaks, tube dislodgement, and occlusion...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27846899/contribution-of-submandibular-gland-and-swallowing-structure-sparing-to-post-radiation-therapy-peg-dependence-in-oropharynx-cancer-patients-treated-with-split-neck-imrt-technique
#8
Michael F Gensheimer, Matthew Nyflot, George E Laramore, Jay J Liao, Upendra Parvathaneni
BACKGROUND: Radiation therapy-related dysphagia is worsened by xerostomia. The submandibular glands (SMG) produce saliva rich in lubricating mucins, and sparing the SMG has been shown to reduce xerostomia. The goal of this study was to determine whether SMG sparing IMRT is associated with reduced post-treatment PEG dependence in locally advanced oropharynx cancer patients. METHODS: Patients treated with definitive radiation therapy for oropharynx cancer were included in this retrospective study...
November 15, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27843445/long-term-survival-of-patients-receiving-artificial-nutrition-in-japanese-psychiatric-hospitals
#9
Keiichi Abe, Ryuko Yamashita, Keiko Kondo, Keiko Takayama, Osamu Yokota, Yoshiki Sato, Mitsumasa Kawai, Hideki Ishizu, Tadao Nakashima, Hideki Hayashi, Kenji Nakata, Hiroyuki Asaba, Koichi Kadota, Kazuyoshi Tanaka, Yumi Morisada, Etsuko Oshima, Seishi Terada
BACKGROUND/AIMS: Most patients with dementia suffer from dysphagia in the terminal stage of the disease. In Japan, most elderly patients with dysphagia receive either tube feeding or total parenteral nutrition. METHODS: In this study, we investigated the factors determining longer survival with artificial nutrition. Various clinical characteristics of 168 inpatients receiving artificial nutrition without oral intake in psychiatric hospitals in Okayama Prefecture, Japan, were evaluated...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/27826994/diagnostic-efficacy-of-single-pass-abdominal-multidetector-row-ct-prospective-evaluation-of-a-low-dose-protocol
#10
Luigi Camera, Immacolata Liccardo, Federica Romano, Raffaele Liuzzi, Antonio Rispo, Massimo Imbriaco, Anna Testa, Gaetano Luglio, Simona De Fronzo, Fabiana Castiglione, Luigi Bucci, Arturo Brunetti
OBJECTIVES: To evaluate the diagnostic efficacy of single-pass contrast-enhanced multi-detector CT (CE-MDCT) performed with a low radiation-high contrast (LR-HC) dose protocol in selected patients with non traumatic acute bowel disease. METHODS: Sixty-five (32 M; 33 F; aged 20-67 years) consecutive patients with non traumatic acute bowel disease underwent single-pass CE-MDCT performed 70-100 sec after i.v. bolus injection of a non ionic iodinated contrast media (370 mgI/ml)...
November 9, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27799884/thirty-day-mortality-after-percutaneous-gastrostomy-by-endoscopic-versus-radiologic-placement-a-systematic-review-and-meta-analysis
#11
Joo Hyun Lim, Seung Ho Choi, Changhyun Lee, Ji Yeon Seo, Hae Yeon Kang, Jong In Yang, Su Jin Chung, Joo Sung Kim
BACKGROUND/AIMS: A percutaneous gastrostomy can be placed either endoscopically (percutaneous endoscopic gastrostomy, PEG) or radiologically (radiologically-inserted gastrostomy, RIG). However, there is no consistent evidence of the safety and efficacy of PEG compared to RIG. Recently, 30-day mortality has become considered as the most important surrogate index for evaluating the safety and efficacy of percutaneous gastrostomy. The aim of this meta-analysis was to compare the 30-day mortality rates between PEG and RIG...
October 2016: Intestinal Research
https://www.readbyqxmd.com/read/27796601/short-and-long-term-outcomes-from-percutaneous-endoscopic-gastrostomy-with-jejunal-extension
#12
Wiriyaporn Ridtitid, Glen A Lehman, James L Watkins, Lee McHenry, Evan L Fogel, Stuart Sherman, Gregory A Coté
BACKGROUND: There is a paucity of data regarding the safety and efficacy of percutaneous endoscopic gastrostomy with jejunal extension (PEG-J). We evaluated adverse events related to PEG-J and determined the clinical impact of PEG-J in those with chronic pancreatitis (CP). METHODS: This cohort study included all patients who underwent PEG-J placement in a tertiary-care academic medical center between 2010 and 2012. Main outcome measurements were (1) short- and long-term complications related to PEG-J and (2) changes in weight and hospitalizations during the 12-month period before and after PEG-J in the CP subgroup...
October 28, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27785325/the-role-of-percutaneous-endoscopic-transgastric-jejunostomy-in-the-management-of-enteral-tube-feeding
#13
Ezekiel Wong Toh Yoon
Feeding-related adverse events after percutaneous endoscopic gastrostomy (PEG) such as aspiration pneumonia can impede the use of PEG. Percutaneous endoscopic transgastric jejunostomy (PEG-J) using large-bore jejunal tubes with gastric decompression function may improve outcomes by circumventing gastric passage during enteral nutrition and improving drainage of excessive gastric secretions. This report describes a case where PEG-J was successful in maintaining enteral tube feeding in a 72-year-old man when PEG feeding was not tolerated...
June 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27768666/a-novel-therapy-to-promote-axonal-fusion-in-human-digital-nerves
#14
Ravinder Bamba, Thanapong Waitayawinyu, Ratnam Nookala, David Colton Riley, Richard B Boyer, Kevin W Sexton, Chinnakart Boonyasirikool, Sunyarn Niempoog, Nathaniel D Kelm, Mark D Does, Richard D Dortch, Robert Bruce Shack, Wesley P Thayer
BACKGROUND: Peripheral nerve injury can have a devastating impact on our military and veteran population. Current strategies for peripheral nerve repair include techniques such as nerve tubes, nerve grafts, tissue matrices, and nerve growth guides to enhance the number of regenerating axons. Even with such advanced techniques, it takes months to regain function. In animal models, polyethylene glycol (PEG) therapy has shown to improve both physiologic and behavioral outcomes after nerve transection by fusion of a portion of the proximal axons to the distal axon stumps...
November 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27743318/novel-levodopa-formulations-for-parkinson-s-disease
#15
Maria Eliza Freitas, Marta Ruiz-Lopez, Susan H Fox
Levodopa remains the most effective treatment for Parkinson's disease and is considered the gold standard therapy. However, disease progression and changes in the gastrointestinal tract result in a declining window of treatment response in a majority of patients. Efforts have been made recently to improve levodopa bioavailability either by developing more effective oral formulations or by innovating routes of administration (intestinal infusion, transcutaneous or inhaled levodopa). IPX066 is a novel levodopa-carbidopa (LD/CD) oral formulation combining immediate-release (IR) and extended-release (ER) LD/CD recently approved in the USA and the EU...
October 14, 2016: CNS Drugs
https://www.readbyqxmd.com/read/27737522/percutaneous-endoscopic-gastrostomy-tube-insertion-in-neurodegenerative-disease-a-retrospective-study-and-literature-review
#16
Pamela Sarkar, Alice Cole, Neil J Scolding, Claire M Rice
Background/Aims: With the notable exceptions of dementia, stroke, and motor neuron disease, relatively little is known about the safety and utility of percutaneous endoscopic gastrostomy (PEG) tube insertion in patients with neurodegenerative disease. We aimed to determine the safety and utility of PEG feeding in the context of neurodegenerative disease and to complete a literature review in order to identify whether particular factors need to be considered to improve safety and outcome...
October 13, 2016: Clinical Endoscopy
https://www.readbyqxmd.com/read/27717336/the-protocol-for-a-randomised-controlled-trial-of-the-evaluation-of-the-tolerance-and-safety-of-early-enteral-nutrition-in-children-after-percutaneous-endoscopic-gastrostomy-placement-protocol-version-09-01-2015
#17
Anna Wiernicka, Małgorzata Matuszczyk, Agnieszka Szlagatys-Sidorkiewicz, Ewa Toporowska-Kowalska, Katarzyna Popińska, Urszula Chlebowczyk-Grzybowska, Ewa Hapyn, Jarosław Kierkuś
BACKGROUND: The appropriate time to initiate enteral nutrition after the placement of a percutaneous endoscopic gastrostomy (PEG) tube has been an area of limited research. There are no sufficient randomised prospective controlled trials in the paediatric population comparing the safety and tolerance of early feeding (3 h) after PEG placement. In order to reduce the period of fasting, inadequate nutritional support, and hospitalisation time, we decided to devise this study. METHODS/DESIGN: This study is a multicentre, randomised, open-label trial designed to evaluate the tolerance and safety of early enteral nutrition after PEG placement in children...
October 7, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27701884/ultrasound-assisted-technique-for-challenging-jejunostomy-balloon-tube-replacements
#18
Ana Ponte, Rolando Pinho, Sónia Fernandes, Carlos Fernandes, Iolanda Ribeiro, Joana Silva, Jaime Rodrigues, João Carvalho
The authors present a case of a 38-year-old man with a 4-hour history of accidental removal of a jejunostomy balloon-tube replacement (PEG-18-BRT-S, Cook Medical Inc., Bloomington, USA). The patient had undergone a direct percutaneous endoscopic jejunostomy (DPEJ) ten months ago, before chemoradiotherapy treatment for an esophageal squamous-cell carcinoma (uT3N2cM0). His past medical condition included alcoholic liver disease and distal gastrectomy from a life-threatening duodenal bleeding ulcer.
October 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27700181/laparoscopic-assisted-percutaneous-endoscopic-gastrostomy-combined-with-ct-gc
#19
Kazuya Kato, Yoshiaki Iwasaki, Kazuhiko Onodera, Minoru Matsuda, Mineko Higuchi, Kimitaka Kato, Yurina Kato, Masahiko Taniguchi, Hiroyuki Furukawa
PURPOSE: Despite the widespread use of percutaneous endoscopic gastrostomy (PEG) tubes, their placement may be associated with a variety of complications, including gastrocolic fistula. MATERIALS AND METHODS: In total, seven high-risk individuals diagnosed using computed tomography (CT)-gastrocolonography (GC) underwent laparoscopic-assisted PEG (LAPEG) placement. Study endpoints included the success of LAPEG under local anesthetic and intravenous sedation, inability to thread the PEG tube, the eventual tube location, the number of tube adjustments needed, adverse events, the operating time, and PEG tube-related infection...
October 4, 2016: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/27695184/placement-of-the-abbvie-peg-j-tube-for-the-treatment-of-parkinson-s-disease-in-the-interventional-radiology-suite
#20
Mark L Montgomery, Noel K Miner, Michael J Soileau, Douglas K McDonald
The primary treatment for Parkinson's disease is dopaminergic stimulation. Although levodopa has historically been administered orally, maintaining a predictable plasma concentration of the drug is challenging. As a result, enteral administration of carbidopa/levodopa (Duopa) has emerged as a promising tool in the treatment of the disease. This requires placement of an enteric catheter, two of which have been approved by the Food and Drug Administration for delivery of Duopa. The approved tubes are placed using the "peroral" or "pull" technique, a method traditionally requiring endoscopy...
October 2016: Proceedings of the Baylor University Medical Center
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