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https://www.readbyqxmd.com/read/28507748/comparison-of-the-pull-and-introducer-percutaneous-endoscopic-gastrostomy-techniques-in-patients-with-head-and-neck-cancer
#1
Felipe A Retes, Fabio S Kawaguti, Marcelo S de Lima, Bruno da Costa Martins, Ricardo S Uemura, Gustavo A de Paulo, Caterina Mp Pennacchi, Carla Gusmon, Adriana Vs Ribeiro, Elisa R Baba, Sebastian N Geiger, Mauricio P Sorbello, Marco A Kulcsar, Ulysses Ribeiro, Fauze Maluf-Filho
BACKGROUND AND STUDY AIMS: Percutaneous endoscopic gastrostomy (PEG) in head and neck cancer (HNC) patients is associated with higher complication and mortality rates when compared to a general patient population. The pull technique is still the preferred technique worldwide but it has some limitations. The aim of this study is to compare the pull and introducer PEG techniques in patients with HNC. PATIENTS AND METHODS: This study is based on a retrospective analysis of a prospectively collected database of 309 patients with HNC who underwent PEG in the Cancer Institute of São Paulo...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28496536/percutaneous-endoscopic-gastrostomy-in-a-patient-with-continuous-intrathecal-baclofen-infusion-therapy
#2
Ezekiel Wong Toh Yoon, Masuki Kobayashi
Percutaneous endoscopic gastrostomy (PEG) is the method of choice in patients requiring long-term enteral tube feeding. In patients with intrathecal baclofen infusion therapy (IBT) pump implantation, infection via the skin and soft tissue may be an issue of concern. The introducer technique for gastrostomy tube insertion may be useful in reducing the risk of peristomal infection. Although the presence of a PEG tube has been reported as a risk factor for implantation site infection (for newly inserted IBT pumps), whether existing IBT pumps are at risk for infection during or after the placement of a PEG tube is not clear...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28488039/development-of-antimicrobial-coating-by-later-by-layer-dip-coating-of-chlorhexidine-loaded-micelles
#3
Supreeda Tambunlertchai, Siriwan Srisang, Norased Nasongkla
Layer-by-layer (LbL) dip coating, accompanying with the use of micelle structure, allows hydrophobic molecules to be coated on medical devices' surface via hydrogen bonding interaction. In addition, micelle structure also allows control release of encapsulated compound. In this research, we investigated methods to coat and maximize the amount of chlorhexidine (CHX) on silicone surface through LbL dip coating method utilizing hydrogen bonding interaction between PEG on micelle corona and PAA. The number of coated cycles was varied in the process and 90 coating cycles provided the maximum amount of CHX loaded onto the surface...
June 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28469206/novel-technique-to-manage-recurrent-peg-j-tube-dislodgement-with-full-thickness-endoscopic-suturing
#4
Abhishek Agnihotri, Sindhu Barola, Jamie Flickinger, Mouen A Khashab, Vivek Kumbhari
No abstract text is available yet for this article.
May 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28449220/survival-functional-status-and-eating-ability-after-percutaneous-endoscopic-gastrostomy-tube-placement-for-acute-stroke
#5
Karl Meisel, Robert M Arnold, Irena Stijacic Cenzer, John Boscardin, Alexander K Smith
OBJECTIVES: To determine the long-term survival and independence of individuals with stroke and percutaneous endoscopic gastrostomy (PEG) tube placement. DESIGN: Retrospective cohort study. SETTING: A longitudinal nationally representative community-based sample of older adults. PARTICIPANTS: Individuals with stroke who had a PEG tube placed (N = 174, mean age 79, 51% female, 29% African American). MEASUREMENTS: Functional status before incident stroke was determined based on data from the Health and Retirement Study (HRS), a national longitudinal survey of community-dwelling older adults, from 1993 to 2012...
April 27, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28436481/fusions-of-tumor-derived-endothelial-cells-with-dendritic-cells-induces-antitumor-immunity
#6
Yingying Huang, Qiqi Mao, Jian He, Jing Su, Yi Peng, Wei Liang, Zixi Hu, Sufang Zhou, Xiaoling Lu, Yongxiang Zhao
To explore dendritic cells/tumor-derived endothelial cells (DC/EC) fusion cells are potent stimulators of T cells to impact tumor progression. ECs were isolated from mice hepatoma cell line (H22) Xenograft, and dendritic cells were isolated from bone marrow of BALB/c mice, then the isolated ECs were cultured and detected the endothelial surface expression of CD105 by flow cytometry. The endothelial characteristics of ECs were detected by tube formation assay and Dil-Ac-LDL uptake assay. After the fusion with polyethylene glycol (PEG), we used DCs, ECs, DCs mixed ECs as the control groups, DC/EC fusion cells as the experimental group, Secretion of IFN-α and IFN-γ was evaluated, T lymphocyte proliferation and cytotoxic T lymphocytes (CTL) were detected in vitro...
April 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28436419/nontuberculous-mycobacteria-in-gastrostomy-fed-patients-with-cystic-fibrosis
#7
H Al-Momani, A Perry, R Jones, S Bourke, S Doe, J Perry, A Anderson, T Forrest, I Forrest, M Griffin, M Brodlie, J Pearson, C Ward
Multi-drug resistant Mycobacterium abscessus complex (MABSC) is a form of Nontuberculous mycobacteria (NTM) of special, international concern in Cystic Fibrosis (CF). We hypothesised that gastric juice and percutaneous endoscopic gastrostomy (PEG) feeding devices might yield MABSC isolates. Gastric juice and sputa from sixteen adult PEG fed CF patients and five replaced PEG tubes were studied. Bacterial and fungal isolates were cultured. Mycobacterium were identified by rpoB, sodA and hsp65 gene sequencing and strain typed using variable number tandem repeat...
April 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28434096/benefits-and-risks-of-a-percutaneous-endoscopic-gastrostomy-peg-for-decompression-in-patients-with-malignant-gastrointestinal-obstruction
#8
Anne Dittrich, Barbara Schubert, Michael Kramer, Felicitas Lenz, Karin Kast, Ulrich Schuler, Markus K Schuler
PURPOSE: Gastrointestinal obstruction presents many burdens for patients with end-stage abdominal cancer, such as nausea and vomiting. Few detailed data on the efficacy of a percutaneous endoscopic gastrostomy (PEG) for decompression exists. This retrospective cohort study investigates the quantity of symptom relief realized with PEG and the corresponding complications. METHODS: Chart reviews of 75 patients with malignant gastrointestinal obstruction, who received a PEG for decompression, were performed...
April 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28421810/catheter-traction-and-gastric-outlet-obstruction-a-repeated-complication-of-using-a-foley-catheter-for-gastrostomy-tube-replacement
#9
Jorge Fonseca, Gonçalo Nunes, Marta Patita, Rita Barosa, Carla Adriana Santos
BACKGROUND: Percutaneous endoscopic gastrostomy (PEG) is a safe procedure and major morbidity is unusual. However, the number of PEG fed patients is increasing all over the world and complications may become more and more frequent. CASE REPORT: We describe a 73 years old woman with persistent vomit after replacement of the standard PEG tube with a Foley catheter. An upper GI endoscopy showed the catheter pulled into the duodenum causing gastric outlet obstruction...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28405323/the-use-of-enteral-access-for-continuous-delivery-of-levodopa-carbidopa-in-patients-with-advanced-parkinson-s-disease
#10
Julian Cheron, Jacques Deviere, Frederic Supiot, Asuncion Ballarin, Pierre Eisendrath, Emmanuel Toussaint, Vincent Huberty, Carmen Musala, Daniel Blero, Arnaud Lemmers, André Van Gossum, Marianna Arvanitakis
BACKGROUND: Continuous delivery to the jejunum of levodopa-carbidopa is a promising therapy in patients with advanced Parkinson's disease, as it reduces motor fluctuation. Percutaneous endoscopic gastrostomy and jejunal tube (PEG-J) placement is a suitable option for this. However, studies focused in PEG-J management are lacking. OBJECTIVES: We report our experience regarding this technique, including technical success, adverse events and outcomes, in patients with advanced Parkinson's disease...
February 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28362572/indicators-for-enteral-nutrition-use-and-prophylactic-percutaneous-endoscopic-gastrostomy-placement-in-patients-with-head-and-neck-cancer-undergoing-chemoradiotherapy
#11
Nina C van der Linden, Annemieke Kok, Marja J Leermakers-Vermeer, Nicole M de Roos, Remco de Bree, Hester van Cruijsen, Chris H J Terhaard
BACKGROUND: Chemoradiotherapy (CRT) is a major risk factor for malnutrition and dehydration in patients with head and neck cancer. Enteral support is often needed, and a percutaneous endoscopic gastrostomy (PEG) is frequently placed. Specific indicators for PEG placement remain unclear. This study retrospectively determined which factors contributed to enteral nutrition (EN) use and PEG placement in a large patient group to gain insight on potential indicators for PEG placement protocol creation...
April 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28361309/reconstitution-of-a-patterned-neural-tube-from-single-mouse-embryonic-stem-cells
#12
Keisuke Ishihara, Adrian Ranga, Matthias P Lutolf, Elly M Tanaka, Andrea Meinhardt
The recapitulation of tissue development and patterning in three-dimensional (3D) culture is an important dimension of stem cell research. Here, we describe a 3D culture protocol in which single mouse ES cells embedded in Matrigel under neural induction conditions clonally form a lumen containing, oval-shaped epithelial structure within 3 days. By Day 7 an apicobasally polarized neuroepithelium with uniformly dorsal cell identity forms. Treatment with retinoic acid at Day 2 results in posteriorization and self-organization of dorsal-ventral neural tube patterning...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28352884/fountain-streaming-contributes-to-fast-tip-growth-through-regulating-the-gradients-of-turgor-pressure-and-concentration-in-pollen-tubes
#13
ShaoBao Liu, Han Liu, ShangSheng Feng, Min Lin, Feng Xu, Tian Jian Lu
Fountain streaming is a typical microfluidic pattern in plant cells, especially for cells with a high aspect ratio such as pollen tubes. Although it has been found that fountain streaming plays crucial roles in the transport of nutrients and metabolites, the positioning of organelles and the mixing of cytoplasms, its implications for the fast tip growth of pollen tubes remain a mystery. To address this, based on the observations of asiatic lily Lilium Casablanca, we developed physical models for reverse fountain streaming in pollen tubes and solved the hydrodynamics and advection-diffusion dynamics of viscous Stokes flow in the shank and apical region of pollen tubes...
April 19, 2017: Soft Matter
https://www.readbyqxmd.com/read/28335674/an-unexpected-cause-of-transient-diarrhea
#14
Yoen Young Chuah, Yeong Yeh Lee, Tzung Jiun Tsai
Migration of percutaneous endoscopic gastrostomy (PEG) tube to colon with gastro-colonic-cutaneous fistula formation is a rare complication of the procedure. Transient episodic diarrhea following each PEG tube feeding is typical of this complication. We present a 72-year-old man with cerebrovascular disease and scoliosis who encountered episodes of transient diarrhea after each PEG tube feeding. His diarrhea was refractory to medications. Colonoscopy demonstrated a mal-positioned PEG in the transverse colon...
April 4, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28328026/alternative-mass-reference-standards-for-direct-analysis-in-real-time-mass-spectrometry
#15
Robert B Cody, A John Dane
RATIONALE: Mass spectra were acquired with the Direct Analysis in Real Time (DART®) ion source for an amine-terminated polyether used as positive-ion mass reference standards and for several fluorinated materials commonly used as negative-ion reference standards for mass spectrometry. METHODS: A commercial time-of-flight mass spectrometer equipped with a DART ion source was used for all measurements. Mass reference standards deposited onto the sealed end of a glass melting point tube were suspended in the DART gas stream for analysis...
May 30, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28316761/polyethylene-glycol-and-lactulose-versus-lactulose-alone-in-the-treatment-of-hepatic-encephalopathy-in-patients-with-cirrhosis-a-non-inferiority-randomized-controlled-trial
#16
Mohammadreza Naderian, Heshmatollah Akbari, Morteza Saeedi, Amir Ali Sohrabpour
BACKGROUND In this clinical trial, polyethylene glycol (PEG) solution was compared with lactulose in the treatment of hepatic encephalopathy in patients with cirrhosis. METHODS This randomized controlled trial was performed on 40 patients in two groups. The patients in the lactulose group received either 20-30 grams of lactulose orally or by a nasogastric tube, or 200 grams of lactulose enema by a rectal tube. The patients in the PEG-lactulose group received the same amount of oral or rectal lactulose, plus 280 grams of PEG in 4 liters of water orally as a single dose in 30-120 minutes...
January 2017: Middle East Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28301921/health-care-utilization-and-complications-of-endoscopic-esophageal-dilation-in-a-national-population
#17
Abhinav Goyal, Kshitij Chatterjee, Sujani Yadlapati, Shailender Singh
Background/Aims: Esophageal stricture is usually managed with outpatient endoscopic dilation. However, patients with food impaction or failure to thrive undergo inpatient dilation. Esophageal perforation is the most feared complication, and its risk in inpatient setting is unknown. Methods: We used National Inpatient Sample (NIS) database for 2007-2013. International Classification of Diseases, 9th revision, Clinical Modification (ICD-9-CM) codes were used to identify patients with esophageal strictures...
March 17, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28294343/patient-factors-associated-with-unidentified-reactivity-in-solid-phase-and-polyethylene-glycol-antibody-detection-methods
#18
Nichole M Miller, Susan T Johnson, Erica Carpenter, Christine A Naczek, Matthew S Karafin
BACKGROUND: Several publications have reported an increase in nonspecific reactions when automated technologies such as solid phase are used for the detection of red blood cell alloantibodies. However, there is little known about patient-specific factors associated with these reactions and the clinical importance of these nonspecific reactions. STUDY DESIGN AND METHODS: We performed a 6-year retrospective review of our blood bank records and all newly reported unidentified (UID) reactivity using a test tube polyethylene glycol (t-PEG) and solid-phase method for the detection and identification of alloantibodies was recorded...
May 2017: Transfusion
https://www.readbyqxmd.com/read/28282009/low-abdominal-wall-thickness-may-predict-percutaneous-endoscopic-gastrostomy-complications
#19
Melissa K James, Vanessa P Ho, Simon P Tiu, Richard J Tom, Taylor R Klein, Gloria M Melnic, Sebastian D Schubl
Although percutaneous endoscopic gastrostomy (PEG) tube placement is a common and safe procedure to provide enteral feeding, some patients develop complications. The aim of this study was to identify risk factors for the development of post-PEG complications. We hypothesized that patients with low albumin, diabetes, higher body mass index (BMI), thicker abdominal walls, or psychomotor agitation would have more complications. A 2-year retrospective review was performed on patients who received a PEG tube at a single institution...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28255151/abdominal-wall-necrotising-fasciitis-a-rare-but-devastating-complication-of-the-percutaneous-endoscopic-gastrostomy-procedure
#20
M R Mohd Said, R Abdul Rani, R A Raja Ali, C S Ngiu
Percutaneous Endoscopic Gastrostomy (PEG) tubes were often offered to patients requiring long term enteral feeding. Even though the procedure is relatively safe, it is associated with various complications such as peritonitis or even death.1 We presented a case of a 54-year-old gentleman with underlying ischemic stroke and pus discharges from a recently inserted PEG tube. Computed Topography (CT) scan confirmed abdominal wall necrotising fasciitis complicated with hyperosmolar hyperglycaemia state (HHS) and later succumbed after 48 hours of admission...
February 2017: Medical Journal of Malaysia
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