keyword
https://read.qxmd.com/read/38626051/study-protocol-for-the-intraoperative-complications-assessment-and-reporting-with-universal-standards-icarus-global-cross-specialty-surveys-and-consensus
#1
JOURNAL ARTICLE
Giovanni E Cacciamani, Tamir Sholklapper, Michael B Eppler, Aref Sayegh, Lorenzo Storino Ramacciotti, Andre L Abreu, Rene Sotelo, Mihir M Desai, Inderbir S Gill
Annually, about 300 million surgeries lead to significant intraoperative adverse events (iAEs), impacting patients and surgeons. Their full extent is underestimated due to flawed assessment and reporting methods. Inconsistent adoption of new grading systems and a lack of standardization, along with litigation concerns, contribute to underreporting. Only half of relevant journals provide guidelines on reporting these events, with a lack of standards in surgical literature. To address these issues, the Intraoperative Complications Assessment and Reporting with Universal Standard (ICARUS) Global Surgical Collaboration was established in 2022...
2024: PloS One
https://read.qxmd.com/read/38623797/complications-after-nuss-bar-removal-procedure-for-pectus-excavatum-analysis-and-proposal-of-a-safety-protocol
#2
JOURNAL ARTICLE
J P Camacho, R Boudou, P A Lobos, J M Moldes, G R Elmo
OBJECTIVE: The Nuss bar removal procedure may bring about different complications. Some are mild while others can be life-threatening. An adequate surgery setup and the fulfilment of some security steps may reduce their incidence. This study aims to analyze our experience with the complications that occurred during bar removal and our safety protocol for the prevention and management of these complications. MATERIALS AND METHODS: Observational cohort study from a retrospective chart review of all patients who underwent Nuss bar removal from November 2013 to March 2022 at a University hospital...
April 1, 2024: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://read.qxmd.com/read/38619771/early-exercise-through-telerehabilitation-after-bariatric-surgery-is-it-feasible
#3
JOURNAL ARTICLE
Johanna Pino-Zúñiga, Mariela Olivares, Giselle Muñoz, Camilo Boza, Camilo Duque, Jorge Cancino-López
PURPOSE: The feasibility of early telerehabilitation after bariatric surgery is unknown. The objective of this study was to assess the feasibility and perception of engaging in the online exercise protocol in patients during the first month after bariatric surgery. MATERIAL AND METHODS: A total of 67 patients, enrolled in a telerehabilitation program following bariatric surgery, completed a survey assessing their perception of the intensity, discomfort, and safety during exercise sessions...
April 15, 2024: Obesity Surgery
https://read.qxmd.com/read/38617163/the-application-value-of-a-vendor-specific-deep-learning-image-reconstruction-algorithm-in-triple-low-head-and-neck-computed-tomography-angiography
#4
JOURNAL ARTICLE
Qiushuang Zhang, Youyou Lin, Hailun Zhang, Jianrong Ding, Jingli Pan, Shuai Zhang
BACKGROUND: Head and neck computed tomography angiography (CTA) technology has become the noninvasive imaging method of choice for the diagnosis and long-term follow-up of vascular lesions of the head and neck. However, issues of radiation safety and contrast nephropathy associated with CTA examinations remain concerns. In recent years, deep learning image reconstruction (DLIR) algorithms have been increasingly used in clinical studies, demonstrating their potential for dose optimization...
April 3, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38616021/maternal-and-neonatal-effects-of-epidural-levobupivacaine-combined-with-fentanyl-or-sufentanil-for-elective-cesarean-section-in-brachycephalic-breeds
#5
JOURNAL ARTICLE
Glaucia P Kanashiro, Camila M S Lima, Isabela P G A Nicácio, Gabriel M Nicácio, Rejane B Brinholi, Renata N Cassu
The aim of this study was to compare the safety and clinical efficacy of epidural levobupivacaine combined with fentanyl or sufentanil for bitches undergoing elective cesarean-section and the impact of these anesthetic protocols on neonatal viability. The anesthetic protocol consisted of intramuscular morphine (0.2 mg/kg), followed by an intravenous bolus of propofol, in a dose sufficient to allowed the puncture of the lumbosacral space. The dogs were randomly allocated to receive 0.5% levobupivacaine plus fentanyl (2...
April 12, 2024: Topics in Companion Animal Medicine
https://read.qxmd.com/read/38613737/safety-and-efficacy-of-waterproof-casting-for-early-onset-scoliosis
#6
JOURNAL ARTICLE
Keegan T Conry, Lorena V Floccari, Melanie Morscher, Miraides F Brown, Todd F Ritzman
PURPOSE: The efficacy of traditional Mehta casting in the treatment of early onset scoliosis (EOS) is well-established. However, waterproof casting has not been previously described. Inherent advantages of waterproof casting include clearance for bathing/swimming, avoiding cast holidays, and improved family satisfaction. The purpose of this study was to assess the safety and efficacy of waterproof serial casting at controlling curve progression in EOS. METHODS: The current study is an IRB-approved Level IV retrospective consecutive cohort of EOS patients who underwent a serial 75% body weight traction-elongation-flexion Mehta cast protocol with waterproof cast padding...
April 13, 2024: Spine Deformity
https://read.qxmd.com/read/38610735/analgesic-efficacy-and-safety-of-intrathecal-morphine-or-intercostal-levobupivacaine-in-lung-cancer-patients-after-major-lung-resection-surgery-by-videothoracoscopy-a-prospective-randomized-controlled-trial
#7
JOURNAL ARTICLE
Silvia González-Santos, Borja Mugabure, Manuel Granell, Borja Aguinagalde, Iker J López, Ainhoa Aginaga, Inmaculada Zubelzu, Haritz Iraeta, Jon Zabaleta, Jose Miguel Izquierdo, Nuria González-Jorrín, Cristina Sarasqueta, Alejandro Herreros-Pomares
Background : Lung resection using video-assisted thoracoscopic surgery (VATS) improves surgical accuracy and postoperative recovery. Unfortunately, moderate-to-severe acute postoperative pain is still inherent to the procedure, and a technique of choice has not been established for the appropriate control of pain. In this study, we aimed to compare the efficacy and safety of intrathecal morphine (ITM) with that of intercostal levobupivacaine (ICL). Methods : We conducted a single-center, prospective, randomized, observer-blinded, controlled trial among 181 adult patients undergoing VATS (ISRCTN12771155)...
March 28, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38608694/cabozantinib-monotherapy-for-advanced-adrenocortical-carcinoma-a-single-arm-phase-2-trial
#8
JOURNAL ARTICLE
Matthew T Campbell, Vania Balderrama-Brondani, Camilo Jimenez, Gina Tamsen, Leonardo P Marcal, Jeena Varghese, Amishi Y Shah, James P Long, Miao Zhang, Joshua Ochieng, Cara Haymaker, Mouhammed Amir Habra
BACKGROUND: Adrenocortical carcinoma is a rare malignancy with poor response to systemic chemotherapy. Mitotane is the only approved therapy for adrenocortical carcinoma. Cabozantinib is a multikinase inhibitor approved in multiple malignancies. This is the first prospective trial to explore the anti-tumour activity, safety, and pharmacokinetic profile of cabozantinib in patients with advanced adrenocortical carcinoma. METHODS: This investigator-initiated, single-arm, phase 2 trial in adult patients (aged ≥18 years) with advanced adrenocortical carcinoma was done at the University of Texas MD Anderson Cancer Center (Houston, TX, USA)...
April 9, 2024: Lancet Oncology
https://read.qxmd.com/read/38603694/prehab-fai-prehabilitation-for-patients-undergoing-arthroscopic-hip-surgery-for-femoroacetabular-impingement-syndrome-protocol-for-an-assessor-blinded-randomised-controlled-feasibility-study
#9
JOURNAL ARTICLE
Anuj Punnoose, Leica Claydon-Mueller, Alison Rushton, Vikas Khanduja
BACKGROUND: The past decade has seen an exponential growth of minimally invasive surgical procedures. Procedures such as hip arthroscopy have rapidly grown and become the standard of care for patients with Femoroacetabular Impingement Syndrome (FAIS). Although, the results of such procedures are encouraging, a large proportion of patients do not achieve optimal outcomes due to chronicity and deconditioning as a result of delay in diagnosis and increased waiting times amongst other factors...
2024: PloS One
https://read.qxmd.com/read/38600561/safety-and-efficacy-of-ketorolac-in-improving-the-prognosis-of-acute-type-a-aortic-dissection-patients-a-protocol-of-a-randomized-double-blinded-and-placebo-controlled-study
#10
JOURNAL ARTICLE
Zhikang Lv, Tuo Pan, Haitao Zhang, Yapeng Wang, Yusanjian Matniyaz, Yuxian Tang, Lichong Lu, Dongjin Wang
BACKGROUND: Acute type A aortic dissection (aTAAD) is a critical and life-threatening condition. Previous research has demonstrated that the use of ketorolac not only reduces the progression, incidence, and severity of aortic aneurysms in animal models, but also decreases postoperative mortality and complications in patients undergoing open abdominal aortic aneurysm replacement. However, there is a lack of studies investigating the efficacy of ketorolac in treating aTAAD in humans. Therefore, we conducted a study to evaluate the safety and efficacy of ketorolac in patients with aTAAD...
April 10, 2024: Trials
https://read.qxmd.com/read/38599641/-phase-%C3%A2-clinical-trial-of-pd-1-inhibitor-combined-with-chemotherapy-for-locally-advanced-resectable-oral-squamous-cell-carcinoma
#11
JOURNAL ARTICLE
H L Wang, K Yue, Y S Wu, Y S Duan, C Jing, X D Wang
Objective: To explore the effectiveness and safety of programmed death 1(PD-1) inhibitory combined with chemotherapy as a neoadjuvant therapy for locally advanced resectable oral squamous cell carcinoma. Methods: This study was a randomized controlled phase Ⅱ trial. Patients recruited from Tianjin Medical University Cancer Institute and Hospital from July 2021 to February 2023 were randomly divided into two groups in a 1∶1 ratio: the experimental group (Toripalimab combined with albumin paclitaxel and cisplatin) and the control group (albumin paclitaxel and cisplatin); patients in both groups underwent three cycles of neoadjuvant therapy...
April 8, 2024: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://read.qxmd.com/read/38599314/endoscopic-sleeve-gastroplasty-the-identification-of-the-key-procedural-steps-through-a-modified-delphi-method
#12
JOURNAL ARTICLE
Stephanie Joseph, Christopher E McGowan, Pichamol Jirapinyo, Allison R Schulman, Adarsh M Thaker, Barham K Abu Dayyeh, Daniel Maselli, Julia R Amundson, Christopher J Zimmermann, Vanessa N VanDruff, Simon Che, Shun Ishii, Michael B Ujiki
BACKGROUND: Endoscopic sleeve gastroplasty (ESG) is an innovative, minimally invasive bariatric procedure with an excellent safety and efficacy profile in adults with obesity. The purpose of the procedure is to shorten and tubularize the stomach along its greater curvature. Nevertheless, there is some heterogeneity in approach to ESG, which will be important to address as the procedure sees increasingly widespread clinical adoption. Here, we present an expert consensus on standardized ESG technique...
April 8, 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38597484/topical-glyceryl-trinitrate-to-increase-radial-artery-diameter-in-neonates-study-protocol-for-a-randomized-controlled-trial
#13
JOURNAL ARTICLE
Deepika Wagh, Dinesh Pawale, Sanjay Patole, Shripada Rao
BACKGROUND: Newborn infants admitted to the neonatal intensive care unit require arterial cannulation for hemodynamic monitoring and blood sampling. Arterial access is achieved through catheterization of umbilical or peripheral arteries. Peripheral artery cannulation is performed in critically ill newborns, but artery localization and cannulation is often challenging and unsuccessful. Therefore, increasing the internal diameter and preventing vasospasm are important for successful peripheral artery cannulation in neonates...
2024: Crit Care Sci
https://read.qxmd.com/read/38592242/the-safety-and-outcome-of-minimally-invasive-staged-segmental-artery-coil-embolization-mis-2-ace-prior-thoracoabdominal-aortic-aneurysm-repair-a-single-center-study-systematic-review-and-meta-analysis
#14
REVIEW
Vaiva Dabravolskaite, Eleni Xourgia, Drosos Kotelis, Vladimir Makaloski
BACKGROUND: Minimally Invasive Staged Segmental Artery Coil Embolization (MIS2 ACE) is a novel technique of spinal cord preconditioning used to reduce the risk of paraplegia in thoracoabdominal aortic aneurysm (TAAA) repair. In this study, we report our experience with MIS2 ACE, including both degenerative and post-dissection TAAA, while we attempt to systematically summarize relevant data available in the literature. DESIGN: single-center observational study with systematic review of the literature and meta-analysis...
February 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38592093/electrochemotherapy-in-aggressive-hemangioma-of-the-spine-a-case-series-and-narrative-literature-review
#15
JOURNAL ARTICLE
Giuseppe Tedesco, Luigi Emanuele Noli, Cristiana Griffoni, Riccardo Ghermandi, Giancarlo Facchini, Giuliano Peta, Nicolas Papalexis, Emanuela Asunis, Stefano Pasini, Alessandro Gasbarrini
(1) Background: this case series and literature review aims to evaluate the efficacy and safety of electrochemotherapy in the management of aggressive spinal hemangiomas, presenting two distinct cases. (2) Methods: we present two cases of spinal aggressive hemangioma which were refractory to conventional treatments and underwent electrochemotherapy. Case 1 involves a 50-year-old female who presented with an aggressive spinal hemangioma of L1, who previously underwent various treatments including surgery, radio-chemotherapy, and arterial embolization...
February 22, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38590767/application-of-enhanced-recovery-after-surgery-during-the-perioperative-period-in-children-with-meckel-s-diverticulum-a-single-center-prospective-clinical-trial
#16
JOURNAL ARTICLE
Cuicui Wang, Youliang Wang, Ping Zhao, Ting Li, Fan Li, Zhi Li, Yingwen Qi, Xuewu Wang, Weidong Shi, Lina Liu, Gamei Li, Yong Wang
BACKGROUND: Enhanced recovery after surgery (ERAS) has been widely used in adult surgery. However, few studies have reported the efficacy of ERAS in paediatric patients with Meckel's diverticulum (MD), the aim of the study was to prospectively evaluate the safety and efficacy of ERAS in treating MD. METHODS: A prospective randomised controlled study of children with MD admitted to our hospital from Jan 1, 2021 to Dec 31, 2023 were conducted, we developed and implemented an ERAS program for this patients...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38590498/combined-endoscopic-cyclophotocoagulation-and-phacoemulsification-versus-phacoemulsification-alone-in-the-glaucoma-treatment-a-systematic-review-and-meta-analysis
#17
REVIEW
Dillan Cunha Amaral, Ricardo Noguera Louzada, Pedro Henrique Santana Moreira, Lucas Neves de Oliveira, Thaís Tiemi Yuati, Jaime Guedes, Milton Ruiz Alves, Denisse Josefina Mora-Paez, Mário Luiz Ribeiro Monteiro
The complete safety and efficacy of endoscopic cyclophotocoagulation (ECP) remain unclear in the literature and, to our knowledge, there are no current meta-analyses on phaco-ECP versus phacoemulsification alone to date. Thus, we conducted a systematic review and meta-analysis comparing these two strategies through studies, assessing the effectiveness and safety of outcomes in a population with glaucoma. The protocol for this systematic review was registered in the PROSPERO International Prospective Register of Systematic Reviews (CRD42023482376)...
March 2024: Curēus
https://read.qxmd.com/read/38589856/a-phase-ii-iii-randomized-clinical-trial-of-cisplatin-plus-gemcitabine-and-nabpaclitaxel-gap-as-preoperative-chemotherapy-versus-immediate-resection-in-patients-with-resectable-biliary-tract-cancers-btc-at-high-risk-for-recurrence-purity-study
#18
RANDOMIZED CONTROLLED TRIAL
Monica Niger, Federico Nichetti, Lorenzo Fornaro, Chiara Pircher, Federica Morano, Federica Palermo, Lorenza Rimassa, Tiziana Pressiani, Rossana Berardi, Andrea Casadei Gardini, Elisa Sperti, Lisa Salvatore, Davide Melisi, Francesca Bergamo, Salvatore Siena, Stefania Mosconi, Raffaella Longarini, Giuseppina Arcangeli, Salvatore Corallo, Laura Delliponti, Stefano Tamberi, Elena Fea, Giovanni Brandi, Ilario Giovanni Rapposelli, Massimiliano Salati, Paolo Baili, Rosalba Miceli, Silva Ljevar, Ilaria Cavallo, Elisa Sottotetti, Antonia Martinetti, Michele Droz Dit Busset, Carlo Sposito, Maria Di Bartolomeo, Filippo Pietrantonio, Filippo de Braud, Vincenzo Mazzaferro
BACKGROUND: Biliary tract cancers (BTCs) are rare and lethal cancers, with a 5-year survival inferior to 20%(1-3). The only potential curative treatment is surgical resection. However, despite complex surgical procedures that have a remarkable risk of postoperative morbidity and mortality, the 5-year survival rate after radical surgery (R0) is 20-40% and recurrence rates are up to ~ 75%(4-6). Up to ~ 40% of patients relapse within 12 months after resection, and half of these patient will recur systemically(4-6)...
April 8, 2024: BMC Cancer
https://read.qxmd.com/read/38583906/phase-1-randomized-trial-of-inpatient-high-intensity-interval-training-after-major-surgery
#19
JOURNAL ARTICLE
Shambavi J Rao, Ian Solsky, Antonius Gunawan, Perry Shen, Edward Levine, Clancy J Clark
BACKGROUND: High-intensity interval training (HIT) can provide physiologic benefits and may improve postoperative recovery but has not been evaluated in inpatients. This study aimed to evaluate the safety and tolerability of HIT after major surgery. METHODS: We performed a phase I randomized study comparing HIT with low-intensity continuous ambulation (40 m) during the initial inpatient stay after major surgery at a large academic center. Clinicopathologic and pre- and post-exercise physiologic data were captured...
April 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38579345/resection-of-intradural-spinal-lesions-with-concomitant-instrumented-fusion-in-children-a-systematic-review-and-representative-cases
#20
JOURNAL ARTICLE
Kiana Y Prather, Matthew P Baier, Nangorgo J Coulibaly, Mark E Stephens, Sixia Chen, Michael E Omini, Andrew Jea
OBJECTIVE: More than one-third of pediatric patients who undergo resection of intradural spine lesions develop progressive postoperative deformity, with as many as half of these patients subsequently requiring surgical fusion. Intradural spinal procedures with simultaneous instrumented fusion in children, however, are infrequently performed. Moreover, the rationale for patient selection, outcomes, and safety of this single-stage surgery in children has not been systematically investigated...
April 5, 2024: Journal of Neurosurgery. Pediatrics
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