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management of exacerbation of asthma

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https://www.readbyqxmd.com/read/29764909/ohio-pediatric-asthma-repository-opportunities-to-revise-care-practices-to-decrease-time-to-physiologic-readiness-for-discharge
#1
Jeffrey M Simmons, Jocelyn M Biagini Myers, Lisa J Martin, Carolyn M Kercsmar, Christine L Schuler, Valentina V Pilipenko, John W Kroner, Hua He, Stephen R Austin, Huyen-Tran Nguyen, Kristie R Ross, Karen S McCoy, Sherman J Alter, Samantha M Gunkelman, Pierre A Vauthy, Gurjit K Khurana Hershey
BACKGROUND: Large-scale, multisite studies in which researchers evaluate patient- and systems-level factors associated with pediatric asthma exacerbation outcomes are lacking. We sought to investigate patient-level risks and system-level practices related to physiologic readiness for discharge (PRD) in the prospective Ohio Pediatric Asthma Repository. METHODS: Participants were children ages 2 to 17 years admitted to an Ohio Pediatric Asthma Repository hospital for asthma exacerbation...
May 15, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29751088/integrated-behavioral-health-care-for-management-of-stress-in-allergic-diseases
#2
REVIEW
Alyssa Oland, Genery D Booster, Bruce G Bender
OBJECTIVE: The present article will review current findings regarding the management of stress in allergic disease. DATA SOURCES: The present review article uses articles and books published between 1995 and 2017. Approximately 85% of sources used were published in the last 10 years and 60% were published in the last 5 years. The majority of sources are peer-reviewed articles. STUDY SELECTIONS: Articles that focused on allergic diseases such as allergic rhinitis, food allergies, urticaria, and allergic asthma were included in the present review...
May 8, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29750029/mortality-in-copd-patients-according-to-clinical-phenotypes
#3
Rafael Golpe, María Suárez-Valor, Irene Martín-Robles, Pilar Sanjuán-López, Esteban Cano-Jiménez, Olalla Castro-Añón, Luis A Pérez de Llano
Purpose: Grouping COPD subjects into clinical phenotypes might be useful for the management of the disease, but the clinical implications of such classification are still not totally clear, especially regarding prognosis. The primary objective of this study was to assess whether the mortality rates were different between four predefined clinical phenotypes. Patients and methods: This is a retrospective, observational study carried out at the COPD clinic of a University Hospital...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29746147/female-sex-and-gender-in-lung-sleep-health-and-disease-increased-understanding-of-basic-biological-pathophysiological-and-behavioral-mechanisms-leading-to-better-health-for-female-patients-with-lung-disease
#4
MeiLan K Han, Emilio Arteaga-Solis, John Blenis, Ghada Bourjeily, Deborah J Clegg, Dawn DeMeo, Jeanne Duffy, Ben Gaston, Nicola M Heller, Anna Hemnes, Elizabeth Petri Henske, Raksha Jain, Tim Lahm, Lisa H Lancaster, Joyce Lee, Marianne J Legato, Sherry McKee, Reena Mehra, Alison Morris, Y S Prakash, Martin R Stampfli, Rashmi Gopal-Srivastava, Aaron D Laposky, Antonello Punturieri, Lora Reineck, Xenia Tigno, Janine Clayton
Female sex/gender is an under-characterized variable in studies related to lung development and disease. Notwithstanding, many aspects of lung and sleep biology and pathobiology are impacted by female sex and female reproductive transitions. These may manifest as differential gene expression or peculiar organ development. Some conditions are more prevalent in women, such as asthma and insomnia, or in the case of LAM, are seen almost exclusively in women. In other diseases, presentation differs such as the higher frequency of exacerbations experienced by women with COPD or greater cardiac morbidity among women with sleep disordered breathing...
May 10, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29731926/practical-approach-to-lung-health-experience-from-the-republic-of-macedonia
#5
Biljana Ilievska-Poposka, Maja Zakoska, Stefan Talevski
BACKGROUND: Among the adults and children aged 5 yrs who attend PHC settings, 20-30% seeks to care for respiratory symptoms. Over 80-90% of the respiratory patients suffer from acute respiratory infections (ARI), followed by chronic obstructive pulmonary diseases (COPD), asthma, and less frequently with pneumonia and tuberculosis (TB). To improve the quality of care in patients who seek assistance for respiratory symptoms in PHC settings and the efficiency of respiratory service delivery within healthcare systems, WHO has designated several initiatives among which one is PAL (Practical Approach to Lung Health)...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29723943/-aspirin-exacerbated-respiratory-disease-case-based-review
#6
Karen Estefanía Hernández-Moreno, Ricardo Cardona
Aspirin-exacerbated respiratory disease comprises a series of signs and symptoms mainly involving the upper and lower posterior airway after the consumption of cyclooxygenase enzyme inhibitors. Adverse reactions that occur are not considered to be an allergy and are common to all non-steroidal anti-inflammatory drugs, and cross-reactivity between these agents is therefore common. The description of 3 clinical cases serves to review key aspects of this condition, such as epidemiology, pathophysiology, clinical manifestations, diagnosis and management...
January 2018: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29716412/trends-in-asthma-self-management-skills-and-inhaled-corticosteroid-use-during-pregnancy-and-postpartum-from-2004-to-2017
#7
Annelies L Robijn, Megan E Jensen, Peter G Gibson, Heather Powell, Warwick B Giles, Vicki L Clifton, Joerg Mattes, Michael J Peek, Helen L Barrett, Sean K Seeho, Leonie K Callaway, Alistair Abbott, John Attia, Peter A Wark, Vanessa E Murphy
OBJECTIVE: Asthma exacerbations and medication non-adherence are significant clinical problems during pregnancy. While asthma self-management education is effective, the number of education sessions required to maximise asthma management knowledge and inhaler technique and whether improvements persist postpartum, is unknown. This paper describes how asthma knowledge, skills, and inhaled corticosteroid (ICS) use have changed over time. METHODS: Data were obtained from three cohorts of pregnant women with asthma recruited in Newcastle, Australia between 2004-2017 (N = 895)...
May 2, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29692999/research-priorities-for-respiratory-nursing-a-uk-wide-delphi-study
#8
Carol Ann Kelly, Andrew J Kirkcaldy, Melissa Pilkington, Matthew Hodson, Lindsay Welch, Janelle Yorke, Katherine Knighting
Respiratory nurses make a significant contribution to the delivery of respiratory healthcare, but there is a dearth of nurse-led, practice-focused, published research. Using a modified three-round Delphi, this study sought to identify research priorities for respiratory nursing to inform a national research strategy. Study information and the survey link were sent electronically to members of UK professional respiratory organisations. Round 1 had 78 items across 16 topics, informed by a systematic literature review...
April 2018: ERJ Open Research
https://www.readbyqxmd.com/read/29688023/passive-nocturnal-physiologic-monitoring-enables-early-detection-of-exacerbations-in-asthmatic-children-a-proof-of-concept-study
#9
Michelle F Huffaker, Michael Carchia, Bronwyn U Harris, William C Kethman, Todd E Murphy, Charlotte C D Sakarovitch, FeiFei Qin, David N Cornfield
RATIONALE: Asthma management depends on prompt identification of symptoms, which challenges both patients and providers. In asthma, a misapprehension of health between exacerbations can compromise compliance. Thus, there is a need for a tool that permits objective longitudinal monitoring without increasing the burden of patient compliance. OBJECTIVES: We sought to determine whether changes in nocturnal physiology are associated with asthma symptoms in pediatric patients...
April 24, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29662064/the-use-of-electronic-alerts-in-primary-care-computer-systems-to-identify-the-excessive-prescription-of-short-acting-beta-2-agonists-for-people-with-asthma-a-systematic-review
#10
REVIEW
Shauna McKibben, Anna De Simoni, Andy Bush, Mike Thomas, Chris Griffiths
Computers are increasingly used to improve prescribing decisions in the management of long-term conditions however the effects on asthma prescribing remain unclear. We aimed to synthesise the evidence for the use of computerised alerts that identify excessive prescribing of short-acting beta2 -agonists (SABAs) to improve asthma management for people with asthma. MEDLINE, CINAHL, Embase, Cochrane and Scopus databases (1990-2016) were searched for randomised controlled trials using electronic alerts to identify excessive prescribing of SABAs for people with asthma in primary care...
April 16, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29650028/a-rare-presentation-of-pulmonary-sarcoidosis-as-a-solitary-lung-mass-a-case-report
#11
Dylan W Kelleher, Madeleine Yaggi, Robert Homer, Erica L Herzog, Changwan Ryu
BACKGROUND: Sarcoidosis is a multisystem, chronic granulomatous disease of unknown etiology that predominantly affects the lungs. Pulmonary sarcoidosis classically presents with constitutional symptoms and computed tomographic scan findings of bilateral, symmetric micronodules in a peribronchovascular distribution with upper and middle lung zone predominance accompanied by bilateral, symmetric hilar lymphadenopathy. A solitary lung mass is a rare finding for pulmonary sarcoidosis, and with its associated constitutional symptoms, it strongly mimics a malignancy...
April 13, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29642904/relationships-between-aeroallergen-levels-and-hospital-admissions-for-asthma-in-the-brussels-capital-region-a-daily-time-series-analysis
#12
Ariane Guilbert, Bianca Cox, Nicolas Bruffaerts, Lucie Hoebeke, Ann Packeu, Marijke Hendrickx, Koen De Cremer, Sandrine Bladt, Olivier Brasseur, An Van Nieuwenhuyse
BACKGROUND: Outdoor pollen grain and fungal spore concentrations have been associated with severe asthma exacerbations at the population level. The specific impact of each taxon and the concomitant effect of air pollution on these symptoms have, however, still to be better characterized. This study aimed to investigate the short-term associations between ambient concentrations of various aeroallergens and hospitalizations related to asthma in the Brussels-Capital Region (Belgium), an area recording especially high rates of admissions...
April 11, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29627457/relationship-of-inhaled-corticosteroid-adherence-to-asthma-exacerbations-in-patients-with-moderate-to-severe-asthma
#13
Alberto Papi, Dermot Ryan, Joan B Soriano, Henry Chrystyn, Leif Bjermer, Roberto Rodríguez-Roisin, Myrna B Dolovich, Mark Harris, Lucy Wood, Maria Batsiou, Susannah I Thornhill, David B Price
BACKGROUND: Patients with asthma and elevated blood eosinophils are at increased risk of severe exacerbations. Management of these patients should consider non-adherence to inhaled corticosteroid (ICS) therapy as a factor for increased exacerbation risk. OBJECTIVE: To investigate whether poor adherence to ICS therapy explains the occurrence of asthma exacerbations in patients with elevated blood eosinophil levels. METHODS: This historical cohort study identified patients within the Optimum Patient Care Research Database, aged ≥18 years, at Global Initiative for Asthma (GINA) steps 3 or 4, with ≥2 ICS prescriptions during the year prior to clinical review...
April 5, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29627424/asthma-across-the-lifespan-time-for-a-paradigm-shift
#14
Stanley J Szefler
We have a unique opportunity to significantly reduce the worldwide burden of asthma in children and impact respiratory outcomes in adults. However, this will require a paradigm shift that is directed at altering the natural history of asthma, reducing asthma exacerbations and preventing long-term adverse outcomes of childhood asthma. Attention should continue to be directed toward minimizing risk as well as impairment with a goal to achieve optimal control. Based on several NIH studies conducted over the last 10 years we now have the tools necessary to accomplish this goal...
April 5, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29624458/burden-of-asthma-among-patients-adherent-to-ics-laba-a-real-world-study
#15
Jill Davis, Frank Trudo, James Siddall, Mark Small
OBJECTIVES: Asthma is a chronic respiratory condition with a U.S. prevalence of 7.4%. Despite numerous treatment options, asthma remains poorly controlled in some patients. Uncontrolled asthma is associated with high healthcare resource utilization (HCRU) and reduced productivity. This study assessed symptoms, productivity, and HCRU of patients adherent to medium/high-dosage inhaled corticosteroid/long-acting beta2-agonist (ICS/LABA) treatment, and the relationship of asthma control with these parameters...
April 6, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29621888/asthma-knowledge-care-and-outcome-during-pregnancy-the-qakcop-study
#16
Wanis H Ibrahim, Fatima Rasul, Mushtaq Ahmad, Abeer S Bajwa, Laith I Alamlih, Anam M El Arabi, Mujahed M Dauleh, Ibrahim Y Abubeker, Muhammed U Khan, Tayseer S Ibrahim, Azdin A Ibrahim
Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. The secondary objective was to identify barriers to asthma control. This was a cross-sectional, face-to-face, prospective study of 80 pregnant women with physician-diagnosed asthma...
January 1, 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29621204/prevalence-of-asthma-asthma-attacks-and-emergency-department-visits-for-asthma-among-working-adults-national-health-interview-survey-2011-2016
#17
Jacek M Mazurek, Girija Syamlal
In 2010, an estimated 8.2% of U.S. adults had current asthma, and among these persons, 49.1% had had an asthma attack during the past year (1). Workplace exposures can cause asthma in a previously healthy worker or can trigger asthma exacerbations in workers with current asthma* (2). To assess the industry- and occupation-specific prevalence of current asthma, asthma attacks, and asthma-related emergency department (ED) visits among working adults, CDC analyzed 2011-2016 National Health Interview Survey (NHIS) data for participants aged ≥18 years who, at the time of the survey, were employed at some time during the 12 months preceding the interview...
April 6, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29575272/going-beyond-zip-code-can-a-person-s-address-help-us-improve-their-acute-care
#18
Erik J Blutinger, Zachary F Meisel, Eugenia C South
Do you know if the man you treated last night with unexplained chest pain lives on a block with a lot of boarded up houses or vacant lots? Does the woman with many repeat visits for asthma exacerbations live in an area with high rates of violent crime? Do these factors in any way relate to their ED visit - the complaint, the workup, the management, your discharge plan? If you knew more about your patient's immediate neighborhood surroundings, would that enhance your ability to deliver high quality acute care? During a busy shift, emergency care providers rarely have time to reflect on how individual and neighborhood socioeconomic factors impact their patient's health...
March 25, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29575037/mechanical-bacterial-lysate-administration-prevents-exacerbation-in-allergic-asthma-children-the-eolia-study
#19
Andrzej Emeryk, Malgorzata Bartkowiak-Emeryk, Zbigniew Jan Raus, Fulvio Braido, Guido Ferlazzo, Giovanni Melioli
BACKGROUND: Despite progress in asthma management, prevention of asthma exacerbation remains challenging in school-aged children with allergic asthma. New therapeutic approaches are needed. Previously, a chemical bacterial lysate has been successfully used in preschool children to reduce wheezing attacks. We assessed the effect of Polyvalent Mechanical Bacterial Lysate (PMBL® ) Tablet on asthma clinical course and control in 6- to 16-year old children with partly controlled or uncontrolled allergic asthma...
March 25, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29567854/risk-factors-of-asthma-exacerbation-based-on-asthma-severity-a-nationwide-population-based-observational-study-in-south-korea
#20
Hye-Rim Kang, Hyun Jin Song, Jin Hyun Nam, Sung-Hyun Hong, So-Young Yang, SangEun Ju, Sang Won Lee, Tae-Bum Kim, Hye-Lin Kim, Eui-Kyung Lee
OBJECTIVES: Asthma exacerbation, associated with many risks factors, can reflect management failure. However, little is known about how risk factors are associated with exacerbation, according to asthma severity. We aimed to investigate differences in risk factors in patients with different asthma severity and evaluate whether risk factors differed between frequent exacerbators and patients with single exacerbation. DESIGN: Nationwide population-based observational study...
March 22, 2018: BMJ Open
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