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https://www.readbyqxmd.com/read/28551729/use-of-platelet-rich-fibrin-in-regenerative-dentistry-a-systematic-review
#1
REVIEW
Richard J Miron, Giovanni Zucchelli, Michael A Pikos, Maurice Salama, Samuel Lee, Vincent Guillemette, Masako Fujioka-Kobayashi, Mark Bishara, Yufeng Zhang, Hom-Lay Wang, Fatiha Chandad, Cleopatra Nacopoulos, Alain Simonpieri, Alexandre Amir Aalam, Pietro Felice, Gilberto Sammartino, Shahram Ghanaati, Maria A Hernandez, Joseph Choukroun
OBJECTIVES: Research across many fields of medicine now points towards the clinical advantages of combining regenerative procedures with platelet-rich fibrin (PRF). This systematic review aimed to gather the extensive number of articles published to date on PRF in the dental field to better understand the clinical procedures where PRF may be utilized to enhance tissue/bone formation. MATERIALS AND METHODS: Manuscripts were searched systematically until May 2016 and separated into the following categories: intrabony and furcation defect regeneration, extraction socket management, sinus lifting procedures, gingival recession treatment, and guided bone regeneration (GBR) including horizontal/vertical bone augmentation procedures...
May 27, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28551728/gingival-biotype-revisited-novel-classification-and-assessment-tool
#2
Kai R Fischer, Andreas Künzlberger, Nikolaos Donos, Stefan Fickl, Anton Friedmann
OBJECTIVES: To evaluate the relationship between gingival biotypes and gingival thickness based on probe transparency through the gingival margin and to assess the sensitivity of a novel classification method. MATERIAL AND METHODS: Sixty adult Caucasian subjects were stratified by their gingival biotype (GB) as defined by the transparency of a prototype double-ended periodontal probe through the buccal gingival margin into "thin" (30 subjects), "moderate" (15 subjects), and "thick" (15 subjects) GB...
May 27, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28551659/chronic-periodontitis-does-not-impact-serum-levels-of-prostate-specific-antigen
#3
Stephan Kruck, Jörg Hennenlotter, Bastian Amend, Maya Geiger, Elitsa Filipova, Tim Neumann, Viktoria Stühler, Tina Schubert, Tilman Todenhöfer, Steffen Rausch, Fabian Huettig, Arnulf Stenzl, Jens Bedke
BACKGROUND/AIM: Chronic periodontitis (CP) has already been associated with altered PSA values in men undergoing biopsy. This study addressed the impact of CP treatment on PSA screening. PATIENTS AND METHODS: Fifty-two asymptomatic men presenting for CP treatment were prospectively enrolled. Total (t)PSA, free (f)PSA and %PSA were determined (n=47) before and after therapy. Pre- and post-therapy values were correlated pairwise regarding patients and dental characteristics...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28551291/periodontal-disease-associated-with-aortic-arch-atheroma-in-patients-with-stroke-or-transient-ischemic-attack
#4
Souvik Sen, Matthew Chung, Viktoriya Duda, Lauren Giamberardino, Alan Hinderliter, Steven Offenbacher
BACKGROUND: Periodontal disease (PD) is associated with recurrent vascular event in stroke or transient ischemic attack (TIA). In this study, we investigated whether PD is independently associated with aortic arch atheroma (AA). We also explored the relationship PD has with AA plaque thickness and other characteristics associated with atheroembolic risk among patients with stroke or TIA. Finally, we confirmed the association between AA and recurrent vascular event in patients with stroke or TIA...
May 24, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28550864/awareness-of-oral-care-reduces-periodontal-inflammation-in-the-elderly-population-but-using-a-powered-toothbrush-showed-no-added-benefit
#5
Romina Brignardello-Petersen
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28550521/assessment-of-periodontal-bone-level-revisited-a-controlled-study-on-the-diagnostic-accuracy-of-clinical-evaluation-methods-and-intra-oral-radiography
#6
Véronique Christiaens, Hugo De Bruyn, Eric Thevissen, Sebastiaan Koole, Melissa Dierens, Jan Cosyn
OBJECTIVES: The accuracy of analogue and especially digital intra-oral radiography in assessing interdental bone level needs further documentation. The aim of this study was to compare clinical and radiographic bone level assessment to intra-surgical bone level registration (1) and to identify the clinical variables rendering interdental bone level assessment inaccurate (2). MATERIALS AND METHODS: The study sample included 49 interdental sites in 17 periodontitis patients...
May 26, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28549330/impact-of-post-traumatic-stress-disorder-on-oral-health
#7
Ana Cristina de Oliveira Solis, Álvaro Cabral Araújo, Felipe Corchs, Marcio Bernik, Érica Panzani Duran, Cláudio Silva, Francisco Lotufo-Neto
BACKGROUND: The stress experienced as an intense and traumatic event can increase the odds of orofacial pain, affect the biomechanics of masticatory system and compromise the periodontal health. This study was conducted to investigate the impact of post-traumatic stress disorder (PTSD) on oral health. METHODS: A case-control study with a convenience sample was designed. Probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing, and plaque were recorded at 6 sites per tooth...
May 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28549260/identification-of-oral-cavity-biofilm-forming-bacteria-and-determination-of-their-growth-inhibition-by-acacia-arabica-tamarix-aphylla-l-and-melia-azedarach-l-medicinal-plants
#8
Muhammad Khalid, Danial Hassani, Muhammad Bilal, Zahid Ali Butt, Muhammad Hamayun, Ayaz Ahmad, Danfeng Huang, Anwar Hussain
OBJECTIVE: Biofilms are complex, multi-species bacterial communities that colonize the oral cavity in the form of plaque and are known to cause dental caries and periodontal disease. Present study demonstrated the potential of three selected medicinal plants against isolated and identified dental biofilm forming strains. METHODS: Pathogenic bacteria from dental biofilms were isolated, cultured, identified by phylogenetic analysis using PCR-based 16S ribosomal RNA (or 16S rRNA) nucleotide sequences and were analyzed for their biofilm forming capability...
May 18, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28548886/association-of-preventive-maintenance-therapy-compliance-and-peri-implant-diseases-a-cross-sectional-study
#9
Alberto Monje, Hom-Lay Wang, José Nart
AIM: This study was aimed at investigating the association between peri-implant maintenance therapy (PIMT) and the frequency of peri-implant diseases, and to further identify the factors that contribute to failure of PIMT compliance. MATERIAL AND METHODS: A cross-sectional study on healthy partial edentulous patients was conducted. These were grouped in the following categories according to the PIMT compliance: regular compliers (RC) (≥2 PIMT/year), erratic compliers (EC) (<2 PIMT/year), and non-compliers (NC) (0 PIMT/year)...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28548885/metformin-inhibits-p-gingivalis-lipopolysaccharide-lps-influenced-inflammatory-response-in-human-gingival-fibroblasts-via-regulating-activating-transcription-factor-3-atf3-expression
#10
Wenyan Kang, Ting Wang, Zhekai Hu, Feng Liu, Yundong Sun, Shaohua Ge
BACKGROUND: Chronic periodontitis is one of the most prevalent oral diseases, which is associated with Porphyromonas gingivalis (P. gingivalis) Lipopolysaccharide (LPS) infection, and has profound effects on type 2 diabetes mellitus (DM2). Metformin, a well-known antidiabetic agent, has been reported to exert anti-inflammatory effects on various cells. This study aimed to investigate the role of metformin on LPS-influenced inflammatory response in human gingival fibroblasts (HGFs). METHODS: Dose-dependent additive effects of metformin on LPS-influenced HGFs were detected...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28548883/simultaneous-detection-of-oral-pathogens-in-subgingival-plaque-and-prostatic-fluid-of-men-with-periodontal-and-prostatic-diseases
#11
John Estemalik, Catherine Demko, Nabil F Bissada, Nishant Joshi, Donald Bodner, Eswar Shankar, Sanjay Gupta
BACKGROUND: Chronic prostatitis (CP) and benign prostatic hyperplasia (BPH) are complex inflammatory conditions for which the etiological determinants are still poorly defined. Periodontitis is caused by subgingival colonizing bacteria in the oral cavity. The causal effect of periodontal disease on prostatic inflammation has not been established. The purpose of this study is to isolate oral pathogens from expressed prostatic secretions of patients with periodontal disease and chronic prostatitis or benign prostatic hyperplasia...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28548373/role-of-de-n-acetylase-pgab-from-aggregatibacter-actinomycetemcomitans-in-exopolysaccharide-export-in-biofilm-mode-of-growth
#12
Mayilvahanan Shanmugam, Abimbola O Oyeniyi, Chaitra Parthiban, Satish Kumar Gujjarlapudi, Gerald B Pier, Narayanan Ramasubbu
Aggregatibacter actinomycetemcomitans, a Gram-negative bacterium, is the causative agent of localized aggressive periodontitis. Attachment to a biotic surface is a critical first step in the A. actinomycetemcomitans infection process for which exopolysaccharides have been shown to be essential. In addition, the pga operon, containing genes encoding for biosynthetic proteins for poly-N-acetyl glucosamine (PNAG), plays a key role in A. actinomycetemcomitans virulence, as a mutant strain lacking the pga operon induces significantly less bone resorption...
May 26, 2017: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/28548243/cross-reactive-saliva-iga-antibodies-to-oxidized-ldl-and-periodontal-pathogens-in-humans
#13
Ramin Akhi, Chunguang Wang, Mikael Kyrklund, Outi Kummu, S Pauliina Turunen, Kati Hyvärinen, Arja Kullaa, Tuula Salo, Pirkko J Pussinen, Sohvi Hörkkö
AIM: Oxidized Low-Density Lipoproteins (oxLDL) are formed as a result of lipid peroxidation and are highly immunogenic and proatherogenic. In this study, saliva antibodies binding to oxLDL, Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa), were characterized and their cross reactivity was evaluated. MATERIAL & METHODS: Resting and stimulated saliva samples were collected from 36 healthy adults (mean age 26 years). Saliva IgA, IgG and IgM autoantibody levels to copper oxidized LDL (CuOx-LDL) and malondialdehyde acetaldehyde modified LDL (MAA-LDL), were determined with chemiluminescence immunoassay...
May 26, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28548211/a-haplotype-block-downstream-of-plasminogen-is-associated-with-chronic-and-aggressive-periodontitis
#14
Matthias Munz, Hong Chen, Yvonne Jockel-Schneider, Knut Adam, Per Hoffman, Klaus Berger, Thomas Kocher, Jörg Meyle, Peter Eickholz, Christof Doerfer, Matthias Laudes, André Uitterlinden, Wolfgang Lieb, Andre Franke, Stefan Schreiber, Steven Offenbacher, Kimon Divaris, Corinna Bruckmann, Bruno G Loos, Soeren Jepsen, Henrik Dommisch, Arne S Schaefer
AIM: The intronic variant rs4252120 in the plasminogen gene (PLG) is known to be associated with aggressive periodontitis (AgP) and atherosclerosis. Here, we examined the chromosomal region spanning PLG for associations with both chronic periodontitis (CP) and AgP. MATERIAL AND METHODS: The association of PLG candidate rs4252120 was tested in a German case-control sample of 1,419 CP cases using the genotyping assay hCV11225947 and 4,562 controls, genotyped with HumanOmni BeadChips...
May 26, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28547773/dental-and-periodontal-health-and-microbiological-and-salivary-conditions-in-patients-with-or-without-diabetes-undergoing-haemodialysis
#15
Gerhard Schmalz, Nora Schiffers, Sandra Schwabe, Radovan Vasko, Gerhard A Müller, Rainer Haak, Rainer F Mausberg, Dirk Ziebolz
OBJECTIVE: The aim of this cross-sectional study was to evaluate the dental and periodontal health, as well as the microbiological and salivary conditions, of patients with and without diabetes mellitus (DM) who are receiving haemodialysis. METHODS: One-hundred and fifty-nine haemodialysis patients were included and divided into groups according to the pre-existing diabetes status: DM or no DM. The oral examination included dental findings and assessment of the periodontal situation...
June 2017: International Dental Journal
https://www.readbyqxmd.com/read/28547733/comparative-evaluation-of-post-traumatic-periodontal-ligament-cell-viability-using-three-storage-media
#16
V V Kokkali, V Bendgude, G Sharangpani
AIM: To evaluate the potential of milk, coconut water and buttermilk in maintaining periodontal ligament cell (PDL) viability. METHODS: Freshly extracted premolars (55) were divided into three experimental groups each having 15 teeth and the negative and positive control groups which had 5 teeth per group. The teeth in the experimental groups were immersed in their respective storage medium for a period of 75 min before the laboratory procedures were performed...
May 25, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28547570/the-effect-of-iloprost-on-cell-proliferation-and-angiogenesis-related-gene-expression-in-human-periodontal-ligament-cells
#17
Thanomsuk Jearanaiphaisarn, Teeranuch Sanharati, Prasit Pavasant, Chalida Nakalekha Limjeerajarus
Periodontal ligament is considered a rich source of mesenchymal stem cells for pulp regeneration. This study investigated the effect of iloprost, a prostacyclin analog, on cell proliferation and the expression of angiogenesis-related genes in human periodontal ligament cells (hPDLs) in vitro. The hPDLs were treated with 10(-9)-10(-6) M iloprost for 1, 6 and 24 h. Cell proliferation was determined by an MTT assay. Vascular endothelial growth factor (VEGF), alpha-1 type I collagen (COL1), and basic fibroblast growth factor (bFGF) mRNA expression were determined by semi-quantitative and qPCR...
May 25, 2017: Odontology
https://www.readbyqxmd.com/read/28544936/effect-of-follicular-dendritic-cell-secreted-protein-on-gene-expression-of-human-periodontal-ligament-cells
#18
Lin Xiang, Na Xin, Ying Yuan, Xiaogang Hou, Junwei Chen, Na Wei, Ping Gong
OBJECTIVE: The objective of this study was to investigate the specific roles of follicular dendritic cell secreted protein (FDC-SP), a protein exists in saliva, in the inhibition of calcium precipitation during periodontal regeneration, as well as affect phenotype expression of human periodontal ligament cells (hPDLCs) during the differentiation process. DESIGN: To investigate this, we applied microarray technology to identify gene expression changes in hPDLCs transfected with FDC-SP and then clustered them according to their biological functions...
May 17, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28544606/effects-of-tooth-storage-media-on-periodontal-ligament-preservation
#19
Md Riasat Hasan, Hiroaki Takebe, Nazmus Shalehin, Nobuko Obara, Takashi Saito, Kazuharu Irie
BACKGROUND / AIMS: An easily available tooth storage medium is required to preserve a tooth after avulsion. Milk and Hank's balanced salt solution (HBSS) are recommended as tooth storage media, and egg white is also reported to be comparable with milk. The aim of the present study was to histologically and immunohistochemically evaluate the effect of different tooth storage media on the periodontal ligament (PDL) of extracted teeth. MATERIAL AND METHODS: This experiment used HBSS, milk and egg white as tooth storage media...
May 24, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28544588/the-in-vivo-th17-and-treg-immune-responses-to-aggregatibacter-actinomycetemcomitans
#20
Susan Mahabady, Natalia Tjokro, Shant Aharonian, Homayoun H Zadeh, Casey Chen, Hooman Allayee, Parish P Sedghizadeh
The periodontal pathogen Aggregatibacter actinomycetemcomitans is known to elicit systemic immune response in infected host, and occasionally causes non-oral infections. Detailed information on its immunopathological responses and the involvement of bacterial virulence factors remains to be elucidated. The aim of this study was to assess the systemic immune response to A. actinomycetemcomitans oral infection. We used an animal model that simulates systemic dissemination of the bacteria by injecting live wild type (WT) D7S-1 and double knockout mutant of leukotoxin and cytolethal distending toxin (ΔltxΔcdt) A...
May 22, 2017: Molecular Oral Microbiology
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