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Tania Køllgaard, Christian Enevold, Klaus Bendtzen, Peter R Hansen, Michael Givskov, Palle Holmstrup, Claus H Nielsen
Cholesterol deposits and pro-inflammatory cytokines play an essential role in the pathogenesis of atherosclerosis, a predominant cause of cardiovascular disease (CVD). Epidemiological evidence has linked periodontal disease (PD) with atherosclerotic CVD. Accordingly, viable periodontal pathogens, including Porphyromonas gingivalis, have been found in atherosclerotic plaques in humans and mice. We aimed to determine whether cholesterol crystals (CHCs) and oral bacteria synergize in the stimulation of human monocytes...
2017: PloS One
Miriam Ting, Matthew S Tenaglia, Gary H Jones, Jon B Suzuki
OBJECTIVES: The objective of this systematic review was to perform a comprehensive overview of systematic reviews and meta-analyses of surgical and patient factors affecting marginal bone loss around osseointegrated dental implants in humans. MATERIAL AND METHODS: Electronic databases were searched for systematic reviews and meta-analyses published up to November 2015. RESULTS: Of the 41 articles selected, 11 evaluated implant factors, 10 evaluated patient factors, 19 evaluated surgical protocol-related factors, and one evaluated all three factors...
February 23, 2017: Implant Dentistry
M Ishizuka, R Kato, Y Moriya, E Noguchi, Y Koide, S Inoue, H Itabe, M Yamamoto
BACKGROUND AND OBJECTIVE: Periodontal disease is a chronic inflammatory disease caused by bacterial infection that can lead to tooth loss. Gingival crevicular fluid can be collected easily and noninvasively. We previously discovered the presence of apolipoprotein B (apoB), the main constituent of low-density lipoprotein, and oxidized low-density lipoprotein (oxLDL) in the gingival crevicular fluid of healthy subjects. In this study, we investigated whether periodontal conditions affect the levels of apoB and oxLDL in gingival crevicular fluid...
February 24, 2017: Journal of Periodontal Research
Erkan Özcan, N Işıl Saygun, Rahşan Ilıkçı, Yıldırım Karslıoğlu, Uğur Muşabak, Sait Yeşillik
Chemerin is a chemoattractant protein that directs inflammatory cells that express its receptor chemokine receptor-like 1 (ChemR23) towards sites of inflammation. C-C chemokine receptor-like 2 (CCRL2), is the other receptor of chemerin, improves the interaction between chemerin and ChemR23. The aim of this study was to evaluate the expression of chemerin and its receptors in gingival tissues with healthy and periodontitis. Tissue biopsy samples were obtained from 20 patients with chronic periodontitis and from the gingiva of 20 healthy individuals undergoing a crown lengthening process...
February 23, 2017: Odontology
Puttu Ganesh, Ramalingam Karthikeyan, Arunachalam Muthukumaraswamy, Joseph Anand
Periodontitis, the chronic inflammatory disease of the supporting tissues of the teeth, has now been implicated in a variety of disparate systemic infections of various organs such as the lungs, heart, kidneys and brain. This review examines various associations involving chronic inflammatory processes arising from the periodontium and Alzheimer's disease, a progressive dementia of the brain with an as yet unknown origin. Causal pathways are also reviewed, e.g. the direct invasion of oral pathogens such as T...
2017: Oral Health & Preventive Dentistry
Anton Sculean
No abstract text is available yet for this article.
2017: Oral Health & Preventive Dentistry
Vanik Rangbulla, Ashutosh Nirola, Madhu Gupta, Priyanka Batra, Mili Gupta
OBJECTIVE: To compare the clinical parameters and levels of salivary immunoglobulin A (IgA), Interleukin-1β (IL-1β) and matrix metalloproteinase-8 (MMP-8) in patients with moderate to severe chronic periodontitis and in individuals with healthy gingiva. METHODS: Levels of clinical parameters plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) along with salivary biomarkers salivary IgA, IL-1β and MMP-8 were recorded among 50 adults (30 test subjects with moderate to severe generalised chronic periodontitis, constituting group A, and 20 periodontally healthy controls - group B)...
2017: Chinese Journal of Dental Research
Shuang Ying Zhou, Hina Mahmood, Cai Fang Cao, Li Jian Jin
OBJECTIVE: To determine the association of high occlusal force (HOF) with the signs of occlusal trauma and periodontal conditions in periodontitis patients, and elaborate the relevant clinical implications. METHODS: Periodontal parameters and signs of occlusal trauma were recorded for 807 teeth in 30 subjects with untreated chronic periodontitis. The T-scan II occlusal analysis system determined the HOF during maximum intercuspation, lateral excursion and protrusive excursion...
2017: Chinese Journal of Dental Research
Eszter Molnár, Bálint Molnár, Zsolt Lohinai, Zsuzsanna Tóth, Zoltán Benyó, Laszló Hricisák, Péter Windisch, János Vág
The laser speckle contrast imaging (LSCI) is proved to be a reliable tool in flap monitoring in general surgery; however, it has not been evaluated in oral surgery yet. We applied the LSCI to compare the effect of a xenogeneic collagen matrix (Geistlich Mucograft®) to connective tissue grafts (CTG) on the microcirculation of the modified coronally advanced tunnel technique (MCAT) for gingival recession coverage. Gingival microcirculation and wound fluid were measured before and after surgery for six months at twenty-seven treated teeth...
2017: BioMed Research International
(no author information available yet)
No abstract text is available yet for this article.
February 24, 2017: British Dental Journal
Sergio Varela Kellesarian, Vanessa Ros Malignaggi, Hasham Abdullah Majoka, Abdulaziz A Al-Kheraif, Tammy Varela Kellesarian, Georgios E Romanos, Fawad Javed
BACKGROUND: The aim of the present systematic review was to assess the efficacy of laser-assisted (low level laser therapy [LLLT], high intensity laser therapy [HILT], or antimicrobial photodynamic therapy [aPDT]) scaling and root planing (SRP) compared with SRP alone on the expression of inflammatory cytokines in the gingival crevicular (GCF) of patients with chronic periodontitis (CP). METHODS: In order to address the focused question: "What is the efficacy of SRP with and without laser and/or aPDT on the expression of pro-inflammatory cytokines in the GCF of patients with CP?" an electronic search without time or language restrictions was conducted up to and including February 2017 in indexed databases using various key words...
February 20, 2017: Photodiagnosis and Photodynamic Therapy
Vanessa Piras, Paolo Usai, Silvia Mezzena, Marta Susnik, Francesca Ideo, Elia Schirru, Elisabetta Cotti
AIM: We evaluated the prevalence of apical periodontitis (AP) and the oral health status in patients with inflammatory bowel diseases (IBDs) treated with immunomodulators, with particular attention to biologic medications (BMs). METHODS: One hundred ten patients, 49 men and 61 women (average age, 46 ± 13.8 years), from the Gastroenterology Unit of the University Hospital with IBDs who were treated with BMs or corticosteroids were included in the study. One hundred ten patients who registered for a dental check-up at the Dental Clinic were matched for age, sex, and physical characteristics with the study group without systemic diseases and not taking medications who were the control...
March 2017: Journal of Endodontics
Camilla Dos Santos Tibúrcio-Machado, Mariana De Carlo Bello, Juliana Maier, Carlos Frederico Brilhante Wolle, Carlos Alexandre Souza Bier
INTRODUCTION: The aim of this study was to perform a critical review of the literature that investigated the association between diabetes and apical periodontitis. METHODS: An electronic search was performed on PubMed/MEDLINE, LILACS, Scientific Electronic Library Online (Scielo), and Cochrane Collaboration databases. Human studies assessing the effect of diabetes in apical periodontitis development or in healing after root canal treatment were included. The outcome was apical periodontitis...
March 2017: Journal of Endodontics
Ibrahim Ethem Yaylali, Anil Teke, Yasar Meric Tunca
INTRODUCTION: This single-blind, randomized controlled trial aimed to evaluate whether foraminal enlargement (FE) with a continuous rotary system during endodontic treatment causes more postoperative pain than nonforaminal enlargement (NFE). METHODS: Seventy qualified patients were randomized into 1 of 2 groups in a 1:1 ratio using a series of random numbers: the FE group and the NFE group. The patients were followed up for 7 days to evaluate between-group differences in the outcome measures...
March 2017: Journal of Endodontics
Sadiye Gunpinar, Nilgun Ozlem Alptekin, Niyazi Dundar
OBJECTIVES: The purpose of this study was to investigate the gingival crevicular fluid (GCF) levels of Monocyte Chemoattractant Protein (MCP)-1 in aggressive periodontitis (AgP) and whether GCF MCP-1 levels differ among localized (L) AgP and generalized (G) AgP. MATERIAL AND METHODS: A total of 160 subjects including, 80 AgP and 80 age and gender matched periodontally healthy (H) controls were recruited in this cross-sectional study (NCT02927704). GCF samples were collected from 160 patients including 50 LAgP, 30 GAgP and 80 H...
February 23, 2017: Oral Diseases
Lili Ye, Yinhua Jiang, Weidong Liu, HaiBiao Tao
OBJECTIVE: The purpose of this study is to investigate the correlation between periodontal disease and oral cancer risk by meta-analysis. METHODS: We searched the electronic databases of PubMed and Wanfang to include the articles related to periodontal disease and oral cancer risk. The association between periodontal disease and oral cancer risk was assessed by odds ratio (OR) and its corresponding 95% confidence interval (95% CI). The publication bias was evaluated by Begg's funnel plot and Egger's line regression test...
December 2016: Journal of Cancer Research and Therapeutics
Mathilde Jalladaud, Mike Lahmi, Corinne Lallam
INTRODUCTION: The periodontal morphotype is a leading feature to be born in mind during surgical, implant, prosthetic, restorative as well as orthodontic treatment. A fragile morphotype will rapidly trigger severe and worrying clinical repercussions for the patient. MATERIALS AND METHODS: In order to minimize the risks involved, sound knowledge of the different morphotypes and of the techniques for clinically evaluating them is a major requirement. These factors need to be regularly reassessed since morphotypes can vary throughout the course of treatment...
March 2017: L' Orthodontie Française
Olivier Sorel, Mohamed Naaim, Pierre-Alexandre Chataigner, Damien Brézulier, Valérie Bertaud
INTRODUCTION: The study examines how the shape of the teeth is taken into account in the context of facial hyperdivergency. One aim was to check out the widely-held belief that the hyperdivergent patient has long teeth. DISCUSSION: Our study found no link between the shape of the teeth and facial hyperdivergency, thus confirming the results in the literature. We examined the issue of how to characterize dental shapes. We found three diversely-appreciated types of shape: rectangular, triangular and ovoid...
March 2017: L' Orthodontie Française
Domingo Martin, Amaia Maté, Paula Zabalegui, Jaime Valenzuela
INTRODUCTION: The FACE philosophy is characterized by clearly defined treatment goals: facial esthetics, dental esthetics, periodontal health, functional occlusion, neuromuscular mechanism and joint function. The purpose is to establish ideal occlusion with good facial esthetics and an orthopedic stable joint position. MATERIALS AND METHODS: The authors present all the concepts of FACE philosophy and illustrate them through one case report. RESULTS: Taking into account all the FACE philosophy concepts increases diagnostic ability and improves the quality and stability of treatment outcomes...
March 2017: L' Orthodontie Française
José Chaqués-Asensi
INTRODUCTION: The extraction-non extraction dilemma is a classic one in the history of orthodontics [2, 19, 30]. In some cases the decision seems to be very clear whereas in some others discrepancies among clinicians can easily be found. Different authors propose different protocols in order to decide whether extractions are necessary in a particular clinical situation. In the last 25 years, the debate has been reframed with new non-extractionists trends based on new treatment philosophies or mechanics...
March 2017: L' Orthodontie Française
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