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https://www.readbyqxmd.com/read/28805207/periodontal-diseases
#1
REVIEW
Denis F Kinane, Panagiota G Stathopoulou, Panos N Papapanou
Periodontal diseases comprise a wide range of inflammatory conditions that affect the supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could lead to tooth loss and contribute to systemic inflammation. Chronic periodontitis predominantly affects adults, but aggressive periodontitis may occasionally occur in children. Periodontal disease initiation and propagation is through a dysbiosis of the commensal oral microbiota (dental plaque), which then interacts with the immune defences of the host, leading to inflammation and disease...
June 22, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28804997/does-dental-hygienist-professional-education-meet-the-needs-of-working-life-educators-views
#2
T-L Jokiaho, P Kaakinen, J I Virtanen
OBJECTIVE: The aim of this study was to describe the compatibility of dental hygienist education with working life from the perspective of their educators. METHODS: We conducted a qualitative study among principal educators of dental hygienists in Finland in 2012-2013. The participants were leading educators of dental hygienists (n = 13) from the four Finnish education units. We used semi-structured interviews based on previous Nordic studies to collect the data and analysed them using inductive content analysis...
August 14, 2017: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/28804947/periodontitis-and-non-alcoholic-fatty-liver-disease-a-population-based-cohort-investigation-in-the-study-of-health-in-pomerania
#3
Aderonke A Akinkugbe, Gary D Slade, A Sidney Barritt, Steven Offenbacher, Astrid Petersmann, Thomas Kocher, Markus M Lerch, Julia Mayerle, Henry Völzke, Gerardo Heiss, Birte Holtfreter
Non-alcoholic fatty liver disease (NAFLD) affects 20-30% of adults with risk factors like obesity and insulin resistance putatively acting through chronic low-grade inflammation. Because periodontitis elicits low-grade inflammation, we hypothesized that it could contribute to NAFLD occurrence. Objective To investigate epidemiologic associations between periodontitis and the incidence of NAFLD among 2,623 participants of the Study of Health in Pomerania METHODS: Periodontitis at baseline was defined as the percentage of sites (0%, 1-30%, ≥30%) with 1) clinical attachment level (CAL) ≥3mm; 2) probing pocket depth (PD) ≥4mm...
August 14, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28804934/complicated-untreated-apical-periodontitis-causing-paraesthesia-a-case-report
#4
Domenico Ricucci, Simona Loghin, José F Siqueira
The purpose of this article was to report a case of untreated apical periodontitis resulting in severe late complications. A patient with an asymptomatic crowned root canal-treated mandibular molar revealing a radiographic substandard endodontic treatment and a slight periapical radiolucency was made aware of the treatment options and opted for no treatment. The lesion slightly increased in size after 6 years, but the tooth remained asymptomatic and endodontic retreatment was again refused. After 4 more years, the patient presented with an abscess and severe pain, complicated by paraesthesia of the left chin and lip...
August 14, 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/28804675/transition-in-dental-treatment-utilization-in-jammu-and-kashmir-india-a-10-year-retrospective-study
#5
Aasim Farooq Shah, Manu Batra, A Ishrat
BACKGROUND: Utilization of health services is the actual attendance by the members of the public at health care facilities to receive care. Utilization, serves as an important tool for oral health policy decision-making. The aim of the present study was to retrospectively gauge and assess the utilization pattern of the dental treatments which was given in hospital for last 10 years. MATERIALS AND METHODS: This retrospective infirmary based study was carried out at Sheri Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Jammu and Kashmir, India...
December 2016: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/28804534/mtor-inhibition-rejuvenates-the-aging-gingival-fibroblasts-through-alleviating-oxidative-stress
#6
Yiru Xia, Mengjun Sun, Yufeng Xie, Rong Shu
The aging periodontium may be vulnerable to periodontal pathogens and poor response to inflammation and susceptible to tumorigenesis. Human gingival fibroblasts (hGFs) through continuously replicative culture served as an in vitro surrogate for aging. To investigate the effects of the mechanistic target of rapamycin (mTOR) inhibition on the aging gingiva, we stimulated the high-passage hGFs with rapamycin (20 nmol/L) for 3 days and 30 days. The cellular and biological changes were examined by immunofluorescence, real-time PCR, ELISA, Western blotting, and flow cytometry...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28803745/further-development-of-the-mronj-minipig-large-animal-model
#7
Sven Otto, Christoph Pautke, Olga Martin Jurado, Dirk Nehrbass, Martin J Stoddart, Michael Ehrenfeld, Stephan Zeiter
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious and potentially severe side effect of antiresorptive therapy with bisphosphonates or denosumab. Recently, a large animal minipig MRONJ model was introduced which led to early necrotic lesions in the majority of extraction sites after bisphosphonate administration. The aim of this project was to modify the preoperative cumulative bisphosphonate dose (zoledronate) and hereby firstly to demonstrate the reliability and reproducibility of the established model...
July 18, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28803674/healing-of-apical-periodontitis-after-nonsurgical-treatment-in-patients-with-type-2-diabetes
#8
Suman Arya, Jigyasa Duhan, Sanjay Tewari, Pankaj Sangwan, Veena Ghalaut, Sameer Aggarwal
INTRODUCTION: The purpose of this prospective study was to compare the success of primary root canal treatment between type 2 diabetic and nondiabetic patients and to investigate the effect of periapical healing on glycated hemoglobin (HbA1c) in type 2 diabetic patients with apical periodontitis. METHODS: Sixty mandibular molars with necrotic pulps and apical radiolucency (size ≥ 2 mm × 2 mm) were included in the study. Based on the HbA1c levels, patients were divided into 2 groups: type 2 diabetic (HbA1c ≥6...
August 10, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28803419/specific-periodontopathic-bacterial-infection-affects-hypertension-in-male-cardiovascular-disease-patients
#9
Norio Aoyama, Jun-Ichi Suzuki, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi, Mitsuaki Isobe
Hypertension (HT) is a systemic disorder that results in the decline of quality of life and death. While patients with periodontitis are at a high risk of HT, little causal information has been provided to date. To clarify the relationship, periodontopathic bacterial infection in cardiovascular patients with or without HT was evaluated. The subjects were patients with (n = 412) or without (n = 199) HT who attended Tokyo Medical and Dental University hospital. Blood examinations and periodontal measurements were performed...
August 12, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28801658/relationship-between-long-working-hours-and-periodontitis-among-the-korean-workers
#10
Wanhyung Lee, Sung-Shil Lim, Byurira Kim, Jong-Uk Won, Jaehoon Roh, Jin-Ha Yoon
We aimed to investigate the association between long working hours and periodontitis, and whether such an association constitutes an exposure-response relationship. Data for this study were collected from the Korea National Health and Nutrition Examination Surveys conducted from 2007 to 2014; 17,533 workers (9,483 of men and 8,050 of women) were included. The odds ratios (OR) and 95% confidence intervals (CI) for the analysis of periodontitis defined as positive of Community Periodontal Index in relation to working hours were calculated using multiple logistic regression models with various stratifications...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28800903/endodontically-treated-teeth-that-receive-nonsurgical-periodontal-treatment-are-more-likely-to-develop-apical-periodontitis-than-periodontally-healthy-teeth
#11
Romina Brignardello-Petersen
No abstract text is available yet for this article.
August 5, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28800670/-oral-health-and-pregnancy-patient-survey-using-a-questionnaire
#12
Tobias Odermatt, Andreas Schötzau, Irene Hoesli
Introduction and Hypothesis This study investigated how well pregnant patients were informed about the causes and effects of gingivitis during pregnancy. Factors such as age, level of education and nationality were taken into account. Data was collected for the overall oral hygiene of the patients and differences between outpatient and inpatient pregnancies were shown. Possible risk factors in terms of birth results were also defined. Methods With the use of a questionnaire, 83 patients (40 outpatients/43 inpatients) were asked about their oral hygiene, as well as their knowledge pertaining to the causes and effects of gingivitis...
August 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28800622/microbial-profile-comparisons-of-saliva-pooled-and-site-specific-subgingival-samples-in-periodontitis-patients
#13
Daniel Belstrøm, Maria Lynn Sembler-Møller, Maria Anastasia Grande, Nikolai Kirkby, Sean Liam Cotton, Bruce J Paster, Palle Holmstrup
OBJECTIVES: The purpose of this study was to compare microbial profiles of saliva, pooled and site-specific subgingival samples in patients with periodontitis. We tested the hypotheses that saliva can be an alternative to pooled subgingival samples, when screening for presence of periopathogens. DESIGN: Site specific subgingival plaque samples (n = 54), pooled subgingival plaque samples (n = 18) and stimulated saliva samples (n = 18) were collected from 18 patients with generalized chronic periodontitis...
2017: PloS One
https://www.readbyqxmd.com/read/28800332/cerebral-oxidative-stress-and-microvasculature-defects-in-tnf-%C3%AE-expressing-transgenic-and-porphyromonas-gingivalis-infected-apoe-mice
#14
Farheen Rokad, Ryan Moseley, Rowan S Hardy, Sasanka Chukkapalli, StJohn Crean, Lakshmyya Kesavalu, Sim K Singhrao
The polymicrobial dysbiotic subgingival biofilm microbes associated with periodontal disease appear to contribute to developing pathologies in distal body sites, including the brain. This study examined oxidative stress, in the form of increased protein carbonylation and oxidative protein damage, in the tumor necrosis factor-α (TNF-α) transgenic mouse that models inflammatory TNF-α excess during bacterial infection; and in the apolipoprotein knockout (ApoE-/-) mouse brains, following Porphyromonas gingivalis gingival monoinfection...
August 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28800203/smokers-have-a-higher-risk-of-inflammatory-peri-implant-disease-than-non-smokers
#15
Önder Gürlek, Pınar Gümüş, Nurcan Buduneli
AIM: To comparatively evaluate peri-implant health status in smokers and non-smokers. MATERIALS AND METHODS: A total of 142 implants (74 implants in non-smokers, 68 in smokers) in 43 smoker or non-smoker systemically healthy patients were included in the study. Demographic and clinical periodontal data were recorded and analysed by Chi-square and Mann-Whitney U tests. RESULTS: Peri-implantitis and mucositis cases were significantly more frequent in the smokers than non-smokers (p=0...
August 11, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28800160/exercise-attenuates-alveolar-bone-loss-and-anxiety-like-behaviour-in-rats-with-periodontitis
#16
Eric F Andrade, Débora R Orlando, Júlia A S Gomes, Renata de C Foureaux, Rafael C Costa, Mary S Varaschin, Gustavo P Rogatto, Rodrigo F de Moura, Luciano J Pereira
AIM: To evaluate the effects of physical training on inflammatory and behavioral parameters of Wistar rats with periodontal disease (PD). MATERIALS AND METHODS: Twenty four animals were distributed in a 2x2 factorial design (with and without exercise, with and without PD). Trained animals swimmed one hour daily during eight weeks. PD was induced by ligature 14 days before the end of experiment and in the last week all animals were submitted to the Marble Burying Test...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800151/cost-comparison-of-prediction-based-decision-making-for-periodontally-affected-molars
#17
Falk Schwendicke, Michael Stolpe, Christian Graetz
AIM: Tooth loss prediction could improve decision-making for periodontally-affected molars. We analyzed the costs of removing all, none or only those molars predicted to be at-risk for extraction during supportive periodontal therapy (SPT). METHODS: This is a model-based study using a German private-payer-perspective. Building mainly on cost and effectiveness data from 2039 molars (301 patients) which received long-term SPT, five (exemplary) prediction/decision strategies were compared: Retaining all molars, removing molars with furcation-involvement (FI) ≥I/≥II/III, or removing all molars...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800146/the-relationship-between-open-versus-normal-contact-point-and-inter-proximal-papilla-dimensions-in-periodontally-healthy-young-adults-a-controlled-clinical-trial
#18
Ronaldo Barcellos de Santana, Jose Luis Carneiro de Miranda, Carolina Miller Mattos de Santana
AIM: The gingival architecture is determined by the spatial orientation of the gingival zenith (GZ) and the interdental papillae (IP). Among the factors commonly associated with the presence and morphology of the IP, the contact point (CP) and the interdental distance relationships have been considered the most important. The objective of the present controlled clinical trial was to evaluate the role of the CP in determining the clinical and morphometric parameters of the interdental papilla...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800144/at-least-three-phenotypes-exist-among-periodontitis-patients
#19
Chryssa Delatola, Bruno G Loos, Evgeni Levin, Marja L Laine
AIM: To identify phenotypes of periodontitis patients by the use of an unsupervised modeling technique (clustering), based on pre-treatment radiographic and microbiological characteristics. MATERIALS AND METHODS: This retrospective study included data from 392 untreated periodontitis patients. Co-regularized spectral clustering algorithm was used to cluster the patients. The resulting clusters were subsequently characterized based on their demographics, radiographic bone loss patterns and microbial data...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28798498/non-parametric-regression-in-clustered-multistate-current-status-data-with-informative-cluster-size
#20
Ling Lan, Dipankar Bandyopadhyay, Somnath Datta
Datasets examining periodontal disease records current (disease) status information of tooth-sites, whose stochastic behavior can be attributed to a multistate system with state occupation determined at a single inspection time. In addition, the tooth-sites remain clustered within a subject, and the number of available tooth-sites may be representative of the true PD status of that subject, leading to an 'informative cluster size' scenario. To provide insulation against incorrect model assumptions, we propose a nonparametric regression framework to estimate state occupation probabilities at a given time and state exit/entry distributions, utilizing weighted monotonic regression and smoothing techniques...
January 2017: Statistica Neerlandica
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