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Renzo Gutierrez-Loli, Miguel A Orrego, Oscar G Sevillano-Quispe, Luis Herrera-Arrasco, Cristina Guerra-Giraldez
MicroRNAs (miRNAs) are short, endogenous, non-coding, single-stranded RNAs involved in post-transcriptional gene regulation. Although, several miRNAs have been identified in parasitic helminths, there is little information about their identification and function in Taenia . Furthermore, the impact of miRNAs in neurocysticercosis, the brain infection caused by larvae of Taenia solium is still unknown. During chronic infection, T. solium may activate numerous mechanisms aimed to modulate host immune responses...
2017: Frontiers in Microbiology
Mirtha Gabriela Soto-Cabezas, Ana María Chávez-Pachas, Juan Carlos Arrasco-Alegre, Martin Javier Alfredo Yagui-Moscoso
Objectives.: To describe the characteristics of tuberculosis epidemiology in Peruvian health workers. Materials and methods.: A descriptive study was performed. It included all health workers with tuberculosis listed in the national epidemiological surveillance system of the Peruvian Ministry of Health, during 2013, 2014, and 2015. Results.: A total of 755 cases of tuberculosis in health workers were reported: 60% worked in hospitals, 28% worked in primary-care facilities, and 12% worked in private facilities...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
Marianela Oré, Eliana Sáenz, Rufino Cabrera, Juan F Sanchez, Maxy B De Los Santos, Carmen M Lucas, Jorge H Núñez, Kimberly A Edgel, Justino Sopan, Jorge Fernández, Andres M Carnero, G Christian Baldeviano, Juan C Arrasco, Paul C F Graf, Andres G Lescano
Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2-36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L...
August 2015: American Journal of Tropical Medicine and Hygiene
Elena Vargas-Linares, Franco Romaní-Romaní, Ricardo López-Ingunza, Juan Arrasco-Alegre, Martín Yagui-Moscoso
The Potos flavus is a nocturnal mammal that lives in neotropical forests from Central America to South America. A study of four cases of rabies in Potos flavus was conducted; these occurred in April 2012 in the Madre de Dios region in Peru and were collected as part of epidemiological surveillance. The analysis performed in the regional reference laboratory of Madre de Dios determined the presence of the rabies virus antigen in three of the brain tissue samples. Results were verified in the Laboratory of Viral Zoonoses of the Peruvian National Institute of Health by direct immunofluorescence...
2014: Revista Peruana de Medicina Experimental y Salud Pública
Victor Alberto Laguna-Torres, Jorge Gómez, Patricia V Aguilar, Julia S Ampuero, Cesar Munayco, Víctor Ocaña, Juan Pérez, María E Gamero, Juan Carlos Arrasco, Irmia Paz, Edward Chávez, Rollin Cruz, Jaime Chavez, Silvia Mendocilla, Elizabeth Gomez, Juana Antigoni, Sofía Gonzalez, Cesar Tejada, Gerardo Chowell, Tadeusz J Kochel
BACKGROUND: We describe the temporal variation in viral agents detected in influenza like illness (ILI) patients before and after the appearance of the ongoing pandemic influenza A (H1N1) (pH1N1) in Peru between 4-January and 13-July 2009. METHODS: At the health centers, one oropharyngeal swab was obtained for viral isolation. From epidemiological week (EW) 1 to 18, at the US Naval Medical Research Center Detachment (NMRCD) in Lima, the specimens were inoculated into four cell lines for virus isolation...
2010: PloS One
J Gomez, Cv Munayco, Jc Arrasco, L Suarez, Va Laguna-Torres, Pv Aguilar, G Chowell, Tj Kochel
This paper presents a description of Peru s experience with pandemic H1N1 influenza 2009. It is based on data from four main surveillance systems: a) ongoing sentinel surveillance of influenza-like illness cases with virological surveillance of influenza and other respiratory viruses; b) sentinel surveillance of severe acute respiratory infections and associated deaths; c) surveillance of acute respiratory infections in children under the age of five years and pneumonia in all age groups; and d) case and cluster surveillance...
2009: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
C V Munayco, J Gomez, V A Laguna-Torres, J Arrasco, T J Kochel, V Fiestas, J Garcia, J Perez, I Torres, F Condori, H Nishiura, G Chowell
We present a preliminary analysis of 1,771 confirmed cases of influenza A(H1N1)v reported in Peru by 17 July including the frequency of the clinical characteristics, the spatial and age distribution of the cases and the estimate of the transmission potential. Age-specific frequency of cases was highest among school age children and young adults, with the lowest frequency of cases among seniors, a pattern that is consistent with reports from other countries. Estimates of the reproduction number lie in the range of 1...
2009: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
P G Palacios Malmaceda, J J Vela Acosta, W Gutiérez Arrasco
Out of 130 children under 12 years of age with a diagnosis of typhoid fever, nine were under two years of age; the youngest was five months old. Six patients were males and the most frequent findings were: high fever, poor physical condition, vomiting, diarrhea, malnutrition, dehydration, meteorism, liver and spleen enlargement, cough, bleeding disorders and central nervous system abnormalities which were suggestive of sepsis. The clinical diagnosis was confirmed in all patients through the isolation of Salmonella typhi in blood cultures...
May 1981: Boletín Médico del Hospital Infantil de México
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