keyword
MENU ▼
Read by QxMD icon Read
search

karla

keyword
https://www.readbyqxmd.com/read/29334616/preoperative-breast-magnetic-resonance-imaging-use-by-breast-density-and-family-history-of-breast-cancer
#1
Louise M Henderson, Rebecca A Hubbard, Weiwei Zhu, Julie Weiss, Karen J Wernli, Martha E Goodrich, Karla Kerlikowske, Wendy DeMartini, Elissa M Ozanne, Tracy Onega
BACKGROUND: Use of preoperative breast magnetic resonance imaging (MRI) among women with a new breast cancer has increased over the past decade. MRI use is more frequent in younger women and those with lobular carcinoma, but associations with breast density and family history of breast cancer are unknown. MATERIALS AND METHODS: Data for 3075 women ages >65 years with stage 0-III breast cancer who underwent breast conserving surgery or mastectomy from 2005 to 2010 in the Breast Cancer Surveillance Consortium were linked to administrative claims data to assess associations of preoperative MRI use with mammographic breast density and first-degree family history of breast cancer...
January 15, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29331845/effect-of-levetiracetam-on-extracellular-amino-acid-levels-in-the-dorsal-hippocampus-of-rats-with-temporal-lobe-epilepsy
#2
Pichardo Macías Luz Adriana, Ramírez Mendiola Blanca Alcira, Contreras García Itzel Jatziri, Zamudio Hernández Sergio Roberto, Chávez Pacheco Juan Luis, Sánchez Huerta Karla Berenice, Mendoza Torreblanca Julieta Griselda
Levetiracetam (LEV) is an anticonvulsant drug with a unique mechanism of action that is not completely understood. However, its activity profile may involve effects on excitatory and/or inhibitory neurotransmission since the primary target of LEV, synaptic vesicle protein 2A, is ubiquitously expressed in all types of synaptic vesicles. Therefore, the objective of the present study was to explore the effect of LEV (300 mg/kg/day for one week, administered via osmotic mini-pumps) on neurotransmitter release and its probable selective effect on extracellular gamma-amino butyric acid (GABA), glutamate (Glu), aspartate (Asp), glutamine (Gln), taurine (Tau) and glycine (Gly) concentrations (using in vivo microdialysis under basal and high-K+ conditions) in the dorsal hippocampus (DH), a region that undergoes major synaptic changes during epilepsy...
January 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29327045/serial-in-office-intralesional-steroid-injections-in-airway-stenosis
#3
Caitlin Bertelsen, Hagit Shoffel-Havakuk, Karla O'Dell, Michael M Johns, Lindsay S Reder
Importance: Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis (SGS/PTS). Its major limitation is restenosis requiring repeated surgery. Intralesional steroid injection (ISI) is a promising adjunctive treatment aimed at prolonging the effects of dilation. Objective: To evaluate the association of serial in-office ISI after endoscopic dilation with surgery-free interval (SFI) in adults with SGS/PTS. Design, Setting, and Participants: A retrospective study of adults with SGS/PTS who underwent at least 2 consecutive in-office ISI at the University of Southern California, Keck School of Medicine, over a 3-year period was conducted...
January 11, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29326026/treatment-outcomes-of-bilateral-medialization-thyroplasty-for-presbylaryngis
#4
Jordan J Allensworth, Karla O'Dell, Aaron Ziegler, Linda Bryans, Paul Flint, Joshua Schindler
BACKGROUND: Presbylaryngis is a common cause of dysphonia in elderly patients. Type I thyroplasty serves to improve glottic closure and vocal quality by correcting bowing. Although unilateral and injection-based procedures are well-characterized in the treatment of broadly defined glottic insufficiency, there are insufficient outcomes data for bilateral medialization thyroplasty in the treatment of presbylaryngis. The aim of this study was to review the change in measures of vocal quality before and after bilateral medialization thyroplasty for presbylaryngis...
January 8, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29325571/development-of-a-hospital-based-patient-reported-outcome-framework-for-lung-cancer-patients-a-study-protocol
#5
Natasha Moloczij, Karla Gough, Benjamin Solomon, David Ball, Linda Mileshkin, Mary Duffy, Mei Krishnasamy
BACKGROUND: Patient-reported outcome (PRO) data is central to the delivery of quality health care. Establishing sustainable, reliable and cost-efficient methods for routine collection and integration of PRO data into health information systems is challenging. This protocol paper describes the design and structure of a study to develop and pilot test a PRO framework to systematically and longitudinally collect PRO data from a cohort of lung cancer patients at a comprehensive cancer centre in Australia...
January 11, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29325517/a-cluster-randomised-controlled-trial-evaluating-the-effectiveness-and-cost-effectiveness-of-the-daily-mile-on-childhood-obesity-and-wellbeing-the-birmingham-daily-mile-protocol
#6
Katie Breheny, Peymane Adab, Sandra Passmore, James Martin, Emma Lancashire, Karla Hemming, Emma Frew
BACKGROUND: Childhood obesity prevention is a public health priority. Children spend a large proportion of their waking time in school; therefore this is an appropriate setting to implement obesity prevention initiatives. Anecdotal reports suggest that implementing The Daily Mile in schools has had positive effects on childhood obesity, academic attainment and wellbeing. This trial aims to measure the effectiveness of The Daily Mile for improving health and wellbeing. METHODS: This protocol describes a cluster randomised controlled trial (RCT) in 40 primary schools located in Birmingham, UK...
January 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29325090/the-5-ws-of-a-gluten-challenge-for-gluten-related-disorders
#7
Karla A Bascuñán, Leda Roncoroni, Federica Branchi, Luisa Doneda, Alice Scricciolo, Francesca Ferretti, Magdalena Araya, Luca Elli
Gluten-related disorders (GRDs) are gradually emerging as epidemiologically relevant diseases, with a global prevalence estimated to be approximately 5% in the population. Conditions related to gluten ingestion include celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS). Although mediated by different pathogenic pathways, these 3 conditions share similar clinical manifestations and can present a difficult differential diagnosis. The gluten challenge (GC) is an important diagnostic tool for GRDs, but there is great variability in regards to deciding which patients should be challenged, what amount of gluten should be used, what the GC duration should be, when and where the GC should occur, and, sometimes, why to conduct a GC...
January 9, 2018: Nutrition Reviews
https://www.readbyqxmd.com/read/29322420/a-comprehensive-protocol-resource-for-performing-pooled-shrna-and-crispr-screens
#8
Leonie A Cluse, Iva Nikolic, Deborah Knight, Piyush B Madhamshettiwar, Jennii Luu, Karla J Cowley, Timothy Semple, Gisela Mir Arnau, Jake Shortt, Ricky W Johnstone, Kaylene J Simpson
This chapter details a compendium of protocols that collectively enable the reader to perform a pooled shRNA and/or CRISPR screen-with methods to identify and validate positive controls and subsequent hits; establish a viral titer in the cell line of choice; create and screen libraries, sequence strategies, and bioinformatics resources to analyze outcomes. Collectively, this provides an overarching resource from the start to finish of a screening project, making this technology possible in all laboratories.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29319745/short-version-of-the-instrument-for-assessment-of-stress-in-nursing-students-in-the-brazilian-reality
#9
Ana Lúcia Siqueira Costa, Rodrigo Marques da Silva, Fernanda Carneiro Mussi, Patrícia Maria Serrano, Eliane da Silva Graziano, Karla de Melo Batista
GOAL: validate a short version of the Instrument for assessment of stress in nursing students in the Brazilian reality. METHOD: Methodological study conducted with 1047 nursing students from five Brazilian institutions, who answered the 30 items initially distributed in eight domains. Data were analyzed in the R Statistical Package and in the latent variable analysis, using exploratory and confirmatory factor analyses, Cronbach's alpha and item-total correlation...
January 8, 2018: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29319415/recognizing-presymptomatic-type-1-diabetes-in-the-workplace
#10
Karla K Giese
Occupational health clinicians often collect and/or interpret annual wellness biometrics for workers. It is now known that type 1 diabetes can present in stages including presymptomatic/normal glucose, presymptomatic/impaired glucose, and symptomatic/hyperglycemia. A workplace wellness screening case illustrates the concepts, along with background pathophysiology, recommendations for new staging and first degree relative screening, and implications for occupational health nurses.
January 1, 2018: Workplace Health & Safety
https://www.readbyqxmd.com/read/29319190/effects-of-response-preference-on-resistance-to-change
#11
Joel E Ringdahl, Wendy K Berg, David P Wacker, Kayla Crook, Maggie A Molony, Kristina K Vargo, Jodi E Neurnberger, Karla Zabala, Christopher J Taylor
Treatments based on differential reinforcement of alternative behavior, such as functional communication training, are widely used. Research regarding the maintenance of related treatment effects is limited. Nevin and Wacker (2013) provided a conceptual framework, rooted in behavioral momentum theory, for the study of treatment maintenance that addressed two components: (a) reemergence of problem behavior, and (b) continued expression of appropriate behavior. In the few studies on this topic, focus has been on variables impacting the reemergence of problem behavior, with fewer studies evaluating the persistence of appropriate behavior...
January 10, 2018: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/29318916/promoting-physical-activity-using-a-wearable-activity-tracker-in-college-students-a-cluster-randomized-controlled-trial
#12
Youngdeok Kim, Angela Lumpkin, Marc Lochbaum, Steven Stegemeier, Karla Kitten
This study examined the effects of utilizing a wearable activity tracker in a credit-based physical activity instructional program (PAIP) for promoting physical activity (PA) in college students. Fourteen PAIP courses in a large public university were randomly assigned into intervention (k = 7; n = 101) and control (k = 7; n = 86) groups. All courses focused on a core curriculum that covers basic exercise and behavioral science contents through lectures and activity sessions. A Misfit Flash activity tracker was provided to students in the intervention group...
January 10, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29318250/razor-printed-sticker-microdevices-for-cell-based-applications
#13
Loren E Stallcop, Yasmín R Álvarez-García, Ana M Reyes-Ramos, Karla P Ramos-Cruz, Molly M Morgan, Yatao Shi, Lingjun Li, David J Beebe, Maribella Domenech, Jay W Warrick
Tape-based razor-printing is a flexible and affordable ultra-rapid prototyping approach for microscale device fabrication. However, integration of this prototyping approach into cell-based assay development has been limited to proof of principle demonstrations. This is in large part due to lack of an established or well-characterized option for biocompatible adhesive tape. Without such an option, integration of these areas will remain unexplored. Therefore, to address this critical hurdle, we characterized microscale devices made using a potentially biocompatible double-sided adhesive, ARCare 90106...
January 10, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29317454/casein-kinase-1-is-a-therapeutic-target-in-chronic-lymphocytic-leukemia
#14
Pavlina Janovska, Jan Verner, Jiri Kohoutek, Lenka Bryjova, Michaela Gregorova, Marta Dzimkova, Hana Skabrahova, Tomasz Radaszkiewicz, Petra Ovesna, Olga Vondalova Blanarova, Tereza Nemcova, Zuzana Hoferova, Katerina Vasickova, Lucie Smyckova, Alexander Egle, Sarka Pavlova, Lucie Poppova, Karla Plevova, Sarka Pospisilova, Vitezslav Bryja
Casein kinase (CK) 1δ/ε is a key component of non-canonical Wnt signaling pathways, which were shown previously to drive pathogenesis of chronic lymphocytic leukemia (CLL). In this study we investigated thoroughly the effects of CK1δ/ε inhibition on the primary CLL cells and analyzed the therapeutic potential in vivo using two murine model systems based on the Eµ-TCL1-induced leukemia (syngeneic adoptive transfer model and spontaneous disease development), which resemble closely the human CLL. We can demonstrate that CK1δ/ε inhibitor PF-670462 significantly blocks microenvironmental interactions - chemotaxis, invasion and communication with stromal cells in primary CLL cells in all major subtypes of CLL...
January 9, 2018: Blood
https://www.readbyqxmd.com/read/29316356/plasma-zinc-levels-in-ecuadorian-mothers-of-infants-with-nonsyndromic-cleft-lip-with-or-without-cleft-palate-a-case-series
#15
Miguel Ángel Jara-Palacios, Angélica Carolina Cornejo, Camila Narváez-Caicedo, Gabriela Moreano, Karla Patricia Vásquez, Cristina Moreno-Izquierdo, Natalia Romero-Sandoval
BACKGROUND: Previous studies have reported an association between maternal zinc deficiency and increased risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in offspring. A high prevalence of zinc deficiency and a high prevalence of NSCL/P have been reported in Ecuador. We postulated that mothers of infants with NSCL/P may have lower serum zinc levels than women from the general population. METHODS: A case series study was conducted from November 2013 to July 2016...
January 8, 2018: Birth Defects Research
https://www.readbyqxmd.com/read/29316317/cytotechnologists-as-coinvestigators-in-anatomical-pathology-research
#16
Karla J Kopp, Marie R Passow, Kristina M Del Rosario, Michael R Christensen, John W O'Shaughnessy, Mary K Bartholet, Mary E Francis, Thomas J Flotte
BACKGROUND: The amount of time available to pathologists with which to perform research is becoming limited due to an increasing manpower shortage in pathology, decreased reimbursement, and increased workload. This is occurring at the same time as demands escalate for pathologists to develop new companion tests, correlate the molecular findings with traditional methods, and assist in the development of individualized medicine. This study examined whether cytotechnologists may be integrated into a research team that uses their expertise in understanding pathology and clinical disease to provide interpretations of experiments that traditionally were performed by pathologists...
January 9, 2018: Cancer
https://www.readbyqxmd.com/read/29315917/covalent-bonding-of-thermoplastics-to-rubbers-for-printable-reel-to-reel-processing-in-soft-robotics-and-microfluidics
#17
Jay M Taylor, Karla Perez-Toralla, Ruby Aispuro, Stephen A Morin
The lamination of mechanically stiff structures to elastic materials is prevalent in biological systems and popular in many emerging synthetic systems, such as soft robotics, microfluidics, stretchable electronics, and pop-up assemblies. The disparate mechanical and chemical properties of these materials have made it challenging to develop universal synthetic procedures capable of reliably adhering to these classes of materials together. Herein, a simple and scalable procedure is described that is capable of covalently laminating a variety of commodity ("off-the-shelf") thermoplastic sheets to silicone rubber films...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29315688/modeling-clustering-and-treatment-effect-heterogeneity-in-parallel-and-stepped-wedge-cluster-randomized-trials
#18
Karla Hemming, Monica Taljaard, Andrew Forbes
Cluster randomized trials are frequently used in health service evaluation. It is common practice to use an analysis model with a random effect to allow for clustering at the analysis stage. In designs where clusters are exposed to both control and treatment conditions, it may be of interest to examine treatment effect heterogeneity across clusters. In designs where clusters are not exposed to both control and treatment conditions, it can also be of interest to allow heterogeneity in the degree of clustering between arms...
January 8, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29313600/dna-damage-in-acute-myeloid-leukemia-patients-of-northern-mexico
#19
Martha I Dávila-Rodríguez, Elva I Cortés-Gutiérrez, Roberto Hernández-Valdés, Karla Guzmán-Cortés, Rosa E De León-Cantú, Ricardo M Cerda-Flores, Enrique Báez-De la Fuente
The purpose of this study was to evaluate DNA damage in the whole genome of peripheral blood leukocytes from patients with acute myeloid leukemia (AML) compared with a control group using DNA breakage detection-fluorescent in situ hybridization (DBD-FISH). Our results suggest that the DNA damage detected in patients with newly diagnosed AML was similar to that observed for the controls; this might be explained by the stimulation of a repair pathway by the pathogenesis itself. These findings indicate that inhibiting the repair pathway could be proposed to enhance the efficacy of chemotherapy...
December 11, 2017: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/29310627/continuity-of-care-is-an-important-and-distinct-aspect-of-childbirth-experience-findings-of-a-survey-evaluating-experienced-continuity-of-care-experienced-quality-of-care-and-women-s-perception-of-labor
#20
Hilde Perdok, Corine J Verhoeven, Jeroen van Dillen, Tjerk Jan Schuitmaker, Karla Hoogendoorn, Jolanda Colli, François G Schellevis, Ank de Jonge
BACKGROUND: To compare experienced continuity of care among women who received midwife-led versus obstetrician-led care. Secondly, to compare experienced continuity of care with a. experienced quality of care during labor and b. perception of labor. METHODS: We conducted a questionnaire survey in a region in the Netherlands in 2014 among 790 women after they gave birth. To measure experienced continuity of care, the Nijmegen Continuity Questionnaire was used. Quality of care during labor was measured with the Pregnancy and Childbirth Questionnaire, and to measure perception of labor we used the Childbirth Perception Scale...
January 8, 2018: BMC Pregnancy and Childbirth
keyword
keyword
116085
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"