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JOURNAL ARTICLE
Michael J Finnan, David Chi, Sarah N Chiang, Justin M Vader, Nicolo L Cabrera, Amy F Kells, Muhammad F Masood, Kunal D Kotkar, Ida K Fox
BACKGROUND: Left ventricular assist devices (LVAD) improve survival for patients with cardiac failure, but LVAD specific infections (VSI) remain a challenge with poorly understood predictive risk factors. Furthermore, the indications and utility of escalating medical treatment to surgical debridement and potential flap reconstruction are not well-characterized. STUDY DESIGN: A retrospective review of consecutive patients undergoing primary LVAD implantation at a tertiary academic center was performed...
April 23, 2024: Journal of the American College of Surgeons
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JOURNAL ARTICLE
Saad M Ezad, Matthew Ryan, Nicholas Barrett, Luigi Camporota, Justyna Swol, Marta V Antonini, Dirk W Donker, Federico Pappalardo, Navin K Kapur, Louise Rose, Divaka Perera
INTRODUCTION: Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) improves end-organ perfusion in cardiogenic shock but may increase afterload, which can limit cardiac recovery. Left ventricular (LV) unloading strategies may aid cardiac recovery and prevent complications of increased afterload. However, there is no consensus on when and which unloading strategy should be used. METHODS: An online survey was distributed worldwide via the EuroELSO newsletter mailing list to describe contemporary international practice and evaluate heterogeneity in strategies for LV unloading...
April 2024: Perfusion
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JOURNAL ARTICLE
Alok Kumar, Sangeeth Raj, Saurabh Singh, Gurpinder S Ghotra, Nikhil Tiwari
INTRODUCTION: Extra Corporeal Membrane Oxygenation (ECMO) has long been used for cardiorespiratory support in the immediate post-paediatric cardiac surgery period with a 2-3% success as per the ELSO registry. Success in recovery depends upon the optimal delivery of critical care to paediatric patients and a comprehensive healthcare team. METHODOLOGY: The survival benefit of children placed on central veno arterial (VA) ECMO following elective cardiac surgeries for congenital heart disease (n = 672) was studied in a cohort of 29 (4...
April 1, 2024: Annals of Cardiac Anaesthesia
#4
REVIEW
Juliette Beaulieu, Christine Vu, Sanjog Kalra, Hamza Ouazani Chahdi, Julie Cousineau, Alexis Matteau, Samer Mansour, E Marc Jolicoeur, Sabrina Jacques, Bénédicte Nauche, Renata Podbielski, Pasquale Ferraro, Charles Poirier, Brian J Potter
BACKGROUND: Severe lung disease frequently presents with both refractory hypoxemia and right ventricular (RV) failure. OxyRVAD is an extra-corporeal membrane oxygenation (ECMO) configuration of RV bypass that also supplements gas exchange. This systematic review summarizes the available literature regarding the use of OxyRVAD in the setting of severe lung disease with associated RV failure. METHODS: PubMed, Embase, and Google Scholar were queried on September 27th , 2023, for articles describing the use of an OxyRVAD configuration...
April 9, 2024: Canadian Journal of Cardiology
#5
REVIEW
Mark G Davies, Joseph P Hart
BACKGROUND: Massive pulmonary embolism (MPE) carries significant 30-day mortality, and a change in societal guidelines has promoted the increasing use of extracorporeal membrane oxygenation (ECMO) in the immediate management of MPE-associated cardiovascular shock. This narrative review examines the current status of ECMO in MPE. METHODS: A literature review was performed from 1982 to 2022 search for the terms Pulmonary embolism and ECMO and refined by examining those publications that covered MPE RESULTS: In the patient with MPE, veno-arterial-ECMO is now recommended as a bridge to interventional therapy...
April 6, 2024: Annals of Vascular Surgery
#6
JOURNAL ARTICLE
Nurgul Seitova, Zaure Tobylbayeva, Mairash Baimuratova, Gulmira Zhauarova, Ruslan Utebaliyev, Almat Bekpan, Darkhan Autalipov, Talgat Ibrayev
No abstract text is available yet for this article.
April 5, 2024: Pediatric Pulmonology
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JOURNAL ARTICLE
Megan B Wanzer, Tracey Wilson, Suzanna Fitzpatrick
PROBLEM: Arterial blood gasses (ABGs) account for an estimated 10-20% of all costs during an ICU stay. Non-clinically indicated ABGs increased costs of care, lengths of stay, ventilator days, and line days, increasing the risk of adverse outcomes in already vulnerable critically ill patients. A cardiac surgery intensive care unit (CSICU) within a large urban mid-Atlantic academic medical center accounted for 31% of the entire institution's ABG analyses between 2018-2019, was identified as a top utilizer due to inappropriate ordering practices compared to current guidelines...
March 2024: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
#8
JOURNAL ARTICLE
Suzana Margareth Lobo, Gaétan Plantefève, Girish Nair, Adilson Joaquim Cavalcante, Nara Franzin de Moraes, Estevao Nunes, Otis Barnum, Claudio Marcel Berdun Stadnik, Maria Patelli Lima, Muriel Lins, Ludhmila Abrahao Hajjar, Christopher Lipinski, Shaheen Islam, Fabiano Ramos, Tiago Simon, Jean-Benoît Martinot, Thomas Guimard, Arnaud Desclaux, Bertrand Lioger, Fernando Carvalho Neuenschwander, Bruno DeSouza Paolino, Alpesh Amin, Samuel Amil Acosta, Daniel Forde Dilling, Edgardo Cartagena, Brian Snyder, Edouard Devaud, Ana Karolina Barreto Berselli Marinho, Suzana Tanni, Patricia Medeiros Milhomem Beato, Stephan De Wit, Vani Selvan, Jeffrey Gray, Ricardo Fernandez, Valérie Pourcher, Lee Maddox, Richard Kay, Anait Azbekyan, Mounia Chabane, Cendrine Tourette, Luis Everton Esmeraldino, Pierre J Dilda, René Lafont, Jean Mariani, Serge Camelo, Sandrine Rabut, Samuel Agus, Stanislas Veillet, Waly Dioh, Rob van Maanen, Capucine Morelot-Panzini
BACKGROUND: SARS-CoV-2 binding to ACE2 is potentially associated with severe pneumonia due to COVID-19. The aim of the study was to test whether Mas-receptor activation by 20-hydroxyecdysone (BIO101) could restore the Renin-Angiotensin System equilibrium and limit the frequency of respiratory failure and mortality in adults hospitalized with severe COVID-19. METHODS: Double-blind, randomized, placebo-controlled phase 2/3 trial. Randomization: 1:1 oral BIO101 (350 mg BID) or placebo, up to 28 days or until an endpoint was reached...
February 2024: EClinicalMedicine
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REVIEW
Tatsiana Romenskaya, Yaroslava Longhitano, Aman Mahajan, Gabriele Savioli, Antonio Voza, Manfredi Tesauro, Christian Zanza
Extracorporeal membrane oxygenation (ECMO) is a cardiac or pulmonary function support system that is used in cases of refractory organ failure in addition to conventional treatment. Currently, Level I evidence is not yet available, which reflects improved outcomes with ECMO in pregnant women, the use in pregnancy should be indicated in selected cases and only in specialized centers. We searched articles in the most important scientific databases from 2009 until 31 December 2023 consulting also the site ClinicalTrials...
March 13, 2024: Journal of Clinical Medicine
#10
JOURNAL ARTICLE
Anne Kristin Fischer, Dirk Stippel, Ali Canbay, Dirk Nierhoff, Michael Thomas, Jan Best, Reinhard Büttner, Uta Drebber
We report on two cases of orthotopic liver transplantation (OLTX) due to SARS-Cov2-associated secondary sclerosing cholangitis (SSC) following long-term artificial respiration and extra-corporal membrane oxygenation in intensive care. Under these conditions, SSC is a rapidly progredient biliary disease featuring degenerative cholangiopathy, loss of bile ducts, ductular and parenchymal cholestasis, biliary fibrosis, and finally cirrhosis. Reduced perfusion and oxygenation of the peribiliary plexus, severe concurrent infections, and secondary medico-toxic effects appear to play a crucial role in the pathogenesis of the disease...
March 25, 2024: Virchows Archiv: An International Journal of Pathology
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EDITORIAL
Sachin Gupta, Deeksha Singh Tomar
How to cite this article: Gupta S, Tomar DS. Acute Kidney Injury and ECMO: Two Sides of the Same Coin. Indian J Crit Care Med 2024;28(1):3-4.
January 2024: Indian Journal of Critical Care Medicine
#12
JOURNAL ARTICLE
Igor Gostyuzhev, Adham Mohamed, Carole E Freiberger-O'Keefe, Michelle M Haines, Jonathan B Kozinn
OBJECTIVE: Our study aimed to compare the outcomes of COVID-19 patients who met a low-risk inclusion criteria for veno-venous extra corporeal membrane oxygenation (VV ECMO) with those who did not meet criteria due to higher risk but were subsequently cannulated. METHODS: This was a retrospective observational cohort study that included adult patients who were placed on VV ECMO for COVID-19 related acute respiratory distress syndrome (ARDS) at a tertiary care academic medical center...
March 20, 2024: International Journal of Artificial Organs
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JOURNAL ARTICLE
Sigridur Olga Magnusdottir, Carsten Simonsen, Dan Stieper Karbing, Bodil Steen Rasmussen, Benedict Kjaergaard
INTRODUCTION: Hypoxic pulmonary vasoconstriction (HPV) can be a challenging clinical problem. It is not fully elucidated where in the circulation the regulation of resistance takes place. It is often referred to as if it is in the arteries, but we hypothesized that it is in the venous side of the pulmonary circulation. METHODS: In an open thorax model, pigs were treated with a veno-venous extra corporeal membrane oxygenator to either oxygenate or deoxygenate blood passing through the pulmonary vessels...
March 20, 2024: Animal Models and Experimental Medicine
#14
JOURNAL ARTICLE
Luca Voltolini, Alberto Salvicchi, Alessandro Gonfiotti, Sara Borgianni, Giovanni Cianchi, Giovanni Mugnaini, Stefano Bongiolatti
BACKGROUND: Elective extra-corporeal membrane oxygenation (ECMO) is rarely used in thoracic surgery, apart from lung transplantation. The purpose of this study was to summarize our institutional experience with the intraoperative use of veno-venous (VV) ECMO in selected cases of main airway surgery. METHODS: We retrospectively analyzed the data of 10 patients who underwent main airway surgery with the support of VV-ECMO between June 2013 and August 2022. RESULTS: Surgical procedures included: three carinal resection and reconstruction with complete preservation of the lung parenchyma, one right upper double-sleeve lobectomy and hemi-carinal resection, and one sleeve resection of the left main bronchus after previous right lower bilobectomy, for thoracic malignancies; four tracheal/carinal repair for extensive traumatic laceration; one extended tracheal resection due to post-tracheostomy stenosis in a patient who had previously undergone a left pneumonectomy...
February 29, 2024: Journal of Thoracic Disease
#15
JOURNAL ARTICLE
Christopher Alexander Hinze, Jan Fuge, Denis Grote-Koska, Korbinian Brand, Hortense Slevogt, Markus Cornberg, Susanne Simon, Oana Joean, Tobias Welte, Jessica Rademacher
BACKGROUND: In clinical routine, voriconazole plasma trough levels ( C min ) out of target range are often observed with little knowledge about predisposing influences. OBJECTIVES: To determine the distribution and influencing factors on voriconazole blood levels of patients treated on intensive- or intermediate care units (ICU/IMC). PATIENTS AND METHODS: Data were collected retrospectively from patients with at least one voriconazole trough plasma level on ICU/IMC ( n = 153) to determine the proportion of sub-, supra- or therapeutic plasma levels...
April 2024: JAC-antimicrobial resistance
#16
JOURNAL ARTICLE
Maria Chalia, Davinder Singh, Stewart G Boyd, Simon Hannam, Aparna Hoskote, Ronit Pressler
To evaluate EEG monitoring during neonatal ECMO and to identify any correlations between seizure detection to abnormal neuroimaging. Eight-year, service evaluation of neonates who received at least one continuous EEG (cEEG) whilst on ECMO at Great Ormond Street Hospital. Pearson's chi-square test and multivariate logistic regression analysis were used to assess clinical and EEG variables association with seizures and neuroimaging findings. Fifty-seven neonates were studied; 57 cEEG recordings were reviewed...
March 15, 2024: European Journal of Pediatrics
#17
REVIEW
Salman Pervaiz Butt, Nabeel Razzaq, Yasir Saleem, Bill Cook, Salman Abdulaziz
INTRODUCTION: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure. This comprehensive review examines the various factors that influence the timing of oxygenator replacement in the ECMO circuit. By considering these factors, clinicians can make informed decisions to ensure timely and effective change-out, enhancing patient outcomes and optimizing the delivery of ECMO therapy...
March 2024: Journal of Extra-corporeal Technology
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JOURNAL ARTICLE
Lis Frykler Abazi, Andreas Liliequist, Felix Böhm, Magnus Hedberg, Moa Simonsson, Anders Bäckman, Malin Ax, Frieder Braunschweig, Linda Mellbin, Rickard Linder, Leif Svensson, Juliane Jurga, Per Nordberg, Mattias Ringh, Sune Forsberg, Jacob Hollenberg
BACKGROUND: The aim of this study was to evaluate the implementation of a novel extra corporeal cardiopulmonary (ECPR) program in the greater Stockholm area with focus on feasibility, safety aspects and clinical outcomes. METHODS: Prospective observational study of ECPR program including patients with OHCA from January 2020 to December 2022, fulfilling ECPR criteria: age 18-65 years, initial shockable rhythm or pulseless electrical activity, witnessed arrest, bystander cardiopulmonary resuscitation and refractory arrest after three cycles of advance cardiac life support...
June 2024: Resuscitation plus
#19
REVIEW
Sindhu Geetha, Neeta Verma, Vivek Chakole
Extracorporeal membrane oxygenation (ECMO) has evolved into a pivotal intervention in critical care, offering a lifeline for patients facing severe respiratory or cardiac failure. This review provides a comprehensive exploration of ECMO, spanning its definition and historical background to its contemporary advancements and ongoing impact in critical care. The versatility of ECMO in addressing diverse critical conditions, careful patient selection criteria, and the nuanced management of complications are discussed...
January 2024: Curēus
#20
JOURNAL ARTICLE
Kana Sugiyama, Osamu Nomura, Jin Irie, Yoshiya Ishizawa, Shuhei Takauji, Mineji Hayakawa, Yoshinori Tamada, Hiroyuki Hanada
BACKGROUND: Rewarming therapies for accidental hypothermia (AH) include extracorporeal membrane oxygenation (ECMO) and non-ECMO related (conventional) therapies. However, there are limited data available to inform the selection of conventional rewarming therapy. The aim of the present study was to explore what patients' factors and which rewarming therapy predicted favorable prognosis. METHODS: This study is a secondary analysis of the Intensive Care with Extra Corporeal membrane oxygenation Rewarming in Accidentally Severe Hypothermia (ICE-CRASH) study, a multicenter prospective, observational study conducted in Japan...
February 15, 2024: American Journal of Emergency Medicine
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