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https://www.readbyqxmd.com/read/28329636/correlation-between-cancer-incidences-and-google-searches-in-the-united-states
#1
Mackenzie R Wehner, Kevin T Nead, Eleni Linos
IntroductionDespite being highly prevalent, keratinocyte carcinomas (basal cell and squamous cell carcinomas lack nationwide registries. Internet search data has emerged as a new method to evaluate previously difficult to quantify public health outcomes and may be useful in keratinocyte carcinoma research.ObjectiveWe aimed to evaluate whether Google search density correlated with known incidences of common cancers in the United States.MethodsWe used the Center for Disease Control's National Program of Cancer Registries ageTadjusted cancer incidences (2008T2012 ...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28314541/risk-of-subsequent-primary-kidney-cancer-after-another-malignancy-a-population-based-study
#2
Omar Abdel-Rahman
BACKGROUND: Population-based data on the development of kidney cancer as a second malignant neoplasm following the diagnosis of other common malignancies are rare. This clinical scenario has been evaluated within the Surveillance, Epidemiology, and End Results (SEER) database. MATERIALS AND METHODS: The SEER-9 database (1973-2013) was queried using the SEER*Stat program to determine the standardized incidence ratios (SIRs) of kidney cancer development following each one of 10 common invasive malignancies (colorectal, breast, prostate, lung, thyroid, corpus uteri, urinary bladder, kidney/renal pelvis, cutaneous melanoma, and non-Hodgkin lymphoma)...
February 27, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28249616/tumor-to-tumor-metastases-papillary-thyroid-carcinoma-into-a-clear-cell-renal-cell-carcinoma
#3
Jin Soo Andy Song, S Mark Taylor, Jonathan Trites, Matthew H Rigby, Martin Joseph Bullock, Jennifer Merrimen, Ricardo Rendon, Robert D Hart
BACKGROUND: Thyroid metastases to distant sites are uncommon incidents, most often metastasizing to the lungs and bones. Rates of metastasis to the kidney are particularly low, ranging from 2.8-3.8% for papillary and 6-20% for follicular variants of well-differentiated thyroid cancers (WDTCs). In rare instances, tumor-to-tumor metastasis between two true primary neoplasms can occurs. This medical phenomenon has previously occurred as a clear cell renal cell carcinoma (CCRCC) spreading to a WDTC...
March 1, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28248052/-endoscopic-removal-of-papillary-tumors-of-upper-urinary-tract
#4
G N Akopyan, Yu G Alyaev, A Z Vinarov, L M Rapoport, M A Gazimiev, D G Tsarichenko, E V Shpot, N I Sorokin, A M Dymov, A M Pshikhachev, V Yu Lekarev, G S Akopyan
AIM: To assess the results of organ-sparing endoscopic treatment of patients with tumors of the upper urinary tract (UUT). MATERIALS AND METHODS: Twenty four patients underwent percutaneous and ureteropyeloscopic interventions for tumors of the upper urinary tract and were followed up at the Urology Clinic, I.M. Sechenov First MSMU. Retrograde removal of benign tumors of the renal pelvis and ureter (tumors sized from 5 to 35 mm), percutaneous removal of papillary carcinoma of renal pelvis of a solitary kidney, percutaneous removal of papillary carcinoma of renal pelvis of only one functioning kidney and percutaneous removal of papillary carcinoma of the lower calyx of the L-shaped kidney were performed in 21, 1, 1 and 1 patients, respectively...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28198599/impact-of-a-bladder-cuff-excision-during-radical-nephroureterectomy-on-cancer-specific-survival-in-the-patients-with-upper-tract-urothelial-cancer-in-korea-a-retrospective-multi-institutional-study
#5
Yun-Sok Ha, Jae-Wook Chung, Seock H Choi, Jun N Lee, Bum S Kim, Tae-Hwan Kim, Eun S Yoo, Tae G Kwon, Seok-Soo Byun, Young D Choi, Ho W Kang, Seok J Yun, Wun-Jae Kim, Hyun T Kim
BACKGROUND: Radical nephroureterectomy (RNU) with bladder cuff excision (BCE) is the surgical principle adopted for the treatment of upper tract urothelial cancers (UTUCs). However, not all RNUs are performed with BCE. We quantified the prognostic impact of RNU with BCE on cancer-specific survival (CSS) in a large patient population. METHODS: In total, 505 patients with UTUC were enrolled from four different institutions. The clinicopathological parameters of patients who underwent RNU with and without BCE were compared...
February 14, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28195651/early-estimates-of-seer-cancer-incidence-2014
#6
Denise Riedel Lewis, Huann-Sheng Chen, Myles G Cockburn, Xiao-Cheng Wu, Antoinette M Stroup, Douglas N Midthune, Zhaohui Zou, Martin F Krapcho, Daniel G Miller, Eric J Feuer
BACKGROUND: Cancer incidence rates and trends for cases diagnosed through 2014 using data reported to the Surveillance, Epidemiology, and End Results (SEER) program in February 2016 and a validation of rates and trends for cases diagnosed through 2013 and submitted in February 2015 using the November 2015 submission are reported. New cancer sites include the pancreas, kidney and renal pelvis, corpus and uterus, and childhood cancer sites for ages birth to 19 years inclusive. METHODS: A new reporting delay model is presented for these estimates for more consistent results with the model used for the usual November SEER submissions, adjusting for the large case undercount in the February submission...
February 14, 2017: Cancer
https://www.readbyqxmd.com/read/28134806/systemic-immunotherapy-for-urothelial-cancer-current-trends-and-future-directions
#7
REVIEW
Shilpa Gupta, David Gill, Austin Poole, Neeraj Agarwal
Urothelial cancer of the bladder, renal pelvis, ureter, and other urinary organs is the fifth most common cancer in the United States, and systemic platinum-based chemotherapy remains the standard of care for first-line treatment of advanced/metastatic urothelial carcinoma (UC). Until recently, there were very limited options for patients who are refractory to chemotherapy, or do not tolerate chemotherapy due to toxicities and overall outcomes have remained very poor. While the role of immunotherapy was first established in non-muscle invasive bladder cancer in the 1970s, no systemic immunotherapy was approved for advanced disease until the recent approval of a programmed death ligand-1 (PD-L1) inhibitor, atezolizumab, in patients with advanced/metastatic UC who have progressed on platinum-containing regimens...
January 27, 2017: Cancers
https://www.readbyqxmd.com/read/28106244/second-malignancy-risk-in-patients-with-bronchopulmonary-carcinoids-epidemiological-results-from-italian-network-of-cancer-registries
#8
Filippo Lococo, Carla Galeone, Claudio Sacchettini, Giovanni Leuzzi, Alfredo Cesario, Massimiliano Paci, Lucia Mangone
PURPOSE: This epidemiological study aimed to determine the prevalence and characteristics of second tumors (STs) in patients with bronchopulmonary carcinoids (BCs). METHODS: Data on neuroendocrine carcinomas (NECs) from the AIRTUM registry (1975-2011) were used for the analysis. Among 32,325 NECs, we focused our analysis on 3,205 patients (9.9%) affected by BCs. The overall ST number and incidence were calculated. The number of STs was compared with the expected cancer number in the healthy Italian population, and the standardized incidence ratio (SIR) and 95% confidence intervals were calculated...
January 16, 2017: Tumori
https://www.readbyqxmd.com/read/28012435/estimation-of-radiation-dosimetry-for-68-ga-hbed-cc-psma-11-in-patients-with-suspected-recurrence-of-prostate-cancer
#9
Mark A Green, Jacob A Eitel, James W Fletcher, Carla J Mathias, Mark A Tann, Thomas Gardner, Michael O Koch, Wendy Territo, Heather Polson, Gary D Hutchins
INTRODUCTION: This study was performed to estimate the human radiation dosimetry for [(68)Ga]Ga-HBED-CC (PSMA-11) ((68)Ga PSMA-11). METHODS: Under an RDRC-approved research protocol, we evaluated the biodistribution and pharmacokinetics of (68)Ga PSMA-11 with serial PET imaging following intravenous administration to nine prostate cancer patients in whom clinical [(11)C]acetate PET/CT exams had been independently performed under Expanded Access IND 118,204. List-mode imaging was performed over the initial 0-10min post-injection with the pelvis in the field-of-view...
November 4, 2016: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/27987509/-preoperative-prognostic-factors-and-preoperative-risk-stratification-of-upper-tract-urothelial-carcinoma
#10
Y C Xing, G Y Xiong, D Fang, Z Zhang, L Cai, L Zhang, Z S He, X S Li, L Q Zhou
OBJECTIVE: To identify the preoperative prognostic factors of upper tract urothelial carcinoma (UTUC) and construct preoperative risk stratification system. METHODS: A retrospective study including 686 patients who were diagnosed with UTUC and received radical nephroureterectomy or partial ureterectomy in Peking University First Hospital during 2003 and 2013. RESULTS: Of the 686 UTUC patients, 303 (44.2%) were male and 383 (55.8%) female. The postoperative pathological examination showed that 203 (29...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27956436/cancer-incidence-and-survival-trends-by-subtype-using-data-from-the-surveillance-epidemiology-and-end-results-program-1992-2013
#11
Anne-Michelle Noone, Kathleen A Cronin, Sean F Altekruse, Nadia Howlader, Denise R Lewis, Valentina I Petkov, Lynne Penberthy
BACKGROUND: Cancers are heterogeneous comprising of distinct tumor subtypes. Therefore, presenting the burden of cancer in the population and trends over time by these tumor subtypes is important to identify patterns and differences in the occurrence of these subtypes, especially to generalize findings to the US general population. METHODS: Using SEER cancer registry data, we present incidence rates according to subtypes for diagnosis years (1992-2013) among men and women for five major cancer sites: breast (female only), esophagus, kidney and renal pelvis, lung and bronchus, and thyroid...
December 12, 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27930581/associations-between-interventions-for-urolithiasis-and-urinary-tract-cancer-among-patients-in-taiwan-the-effect-of-early-intervention
#12
Chien-Liang Lin, Wen-Tsung Huang, Wen-Chou Fan, Yin-Hsun Feng, Chia-Ho Lin, Chian-Shiung Lin, Chih-Cheng Lu, Tse-Chou Cheng, Chao-Jung Tsao, Sheng-Hsiang Lin
The aim of this study was to investigate cancer risk in patients with a history of urolithiasis and to determine whether intervention for calculi attenuated the risk of subsequent urinary tract cancer (UTC).Using data from the National Health Insurance Research Database in Taiwan, we performed a nationwide cohort study enrolling participants (n = 42,732) aged > 30 years who were diagnosed with urinary tract calculi between 2000 and 2009. Age- and gender-matched insured individuals (n = 213,660) found in the health service records over the same period were recruited as the control group...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27900539/seom-clinical-guideline-for-treatment-of-muscle-invasive-and-metastatic-urothelial-bladder-cancer-2016
#13
M Lázaro, E Gallardo, M Doménech, Á Pinto, A González Del Alba, J Puente, O Fernández, A Font, N Lainez, S Vázquez
The goal of this article is to provide recommendations for the diagnosis and treatment of muscle-invasive and metastatic bladder cancer. The diagnosis of muscle-invasive bladder cancer is made by pathologic evaluation after transurethral resection. Recently, a molecular classification has been proposed. Staging of muscle-invasive bladder cancer must be done by computed tomography scans of the chest, abdomen and pelvis and classified on the basis of UICC system. Radical cystectomy and lymph node dissection are the treatment of choice...
December 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27832048/vital-signs-disparities-in-tobacco-related-cancer-incidence-and-mortality-united-states-2004-2013
#14
S Jane Henley, Cheryll C Thomas, Saida R Sharapova, Behnoosh Momin, Greta M Massetti, Deborah M Winn, Brian S Armour, Lisa C Richardson
BACKGROUND: Tobacco use causes at least 12 types of cancer and is the leading preventable cause of cancer. METHODS: Data from the United States Cancer Statistics dataset for 2004-2013 were used to assess incidence and death rates and trends for cancers that can be caused by tobacco use (tobacco-related cancers: oral cavity and pharynx; esophagus; stomach; colon and rectum; liver; pancreas; larynx; lung, bronchus, and trachea; kidney and renal pelvis; urinary bladder; cervix; and acute myeloid leukemia) by sex, age, race, ethnicity, state, county-level poverty and educational attainment, and cancer site...
November 11, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27819754/urological-cancer-related-to-familial-syndromes
#15
Walter Henriques da Costa, George Jabboure, Isabela Werneck da Cunha
Cancer related to hereditary syndromes corresponds to approximately 5-10% of all tumors. Among those from the genitourinary system, many tumors had been identified to be related to genetic syndromes in the last years with the advent of new molecular genetic tests. New entities were described or better characterized, especially in kidney cancer such as hereditary leiomyomatosis renal cell carcinoma (HLRCC), succinate dehydrogenase kidney cancer (SDH-RCC), and more recently BAP1 germline mutation related RCC...
March 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27790508/role-of-urinary-and-serum-carbohydrate-antigen-19-9-as-a-biomarker-in-diagnosis-of-adult-giant-hydronephrosis
#16
Indraneel Banerjee, Vinay Tomar, Sher Singh Yadav, Nachiket Vyas, Suresh Yadav, Brijesh Sathian
INTRODUCTION: The most common cause of adult Giant Hydronephrosis (GH) is congenital Uretero-Pelvic Junction (UPJ) obstruction. Conventional imaging modalities, like Intravenous Urography (IVU) and Computed Tomography Urography (CTU) and radionuclide renal scan can be fallacious. Serum carbohydrate antigen 19-9 (CA19-9) is a useful tumour marker for gastrointestinal and pancreatic cancer. Only a few studies and case reports have shown raised serum levels due to benign hydronephrosis and GH...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27785421/lynch-syndrome-and-exposure-to-aristolochic-acid-in-upper-tract-urothelial-carcinoma-its-clinical-impact
#17
REVIEW
Pierre Colin, Thomas Seisen, Romain Mathieu, Sharohkh F Shariat, Morgan Rouprêt
The purpose of the current review was to describe the clinical risk for Lynch syndrome (LS) after exposure to aristolochic acid (AA) in cases of upper urinary-tract urothelial carcinoma (UTUC). A systematic review of the scientific literature was performed using the Medline database (National Library of Medicine, PubMed) using the following keywords: epidemiology, risk factor, AA, Balkan nephropathy (BNe), LS, hereditary cancer, hereditary non-polyposis colorectal cancer (HNPCC), mismatch repair genes, urothelial carcinomas, upper urinary tract, renal pelvis, ureter, Amsterdam criteria, genetic counselling, mismatch repair genes, genetic instability, microsatellite, and Bethesda guidelines...
October 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/27775761/state-level-cancer-mortality-attributable-to-cigarette-smoking-in-the-united-states
#18
Joannie Lortet-Tieulent, Ann Goding Sauer, Rebecca L Siegel, Kimberly D Miller, Farhad Islami, Stacey A Fedewa, Eric J Jacobs, Ahmedin Jemal
Importance: State-specific information about the health burden of smoking is valuable because state-level initiatives are at the forefront of tobacco control. Smoking-attributable cancer mortality estimates are currently available nationally and by cancer, but not by state. Objective: To calculate the proportion of cancer deaths among adults 35 years and older that were attributable to cigarette smoking in 2014 in each state and the District of Columbia. Design, Setting, and Participants: The population-attributable fraction (PAF) of cancer deaths due to cigarette smoking was computed using relative risks for 12 smoking-related cancers (acute myeloid leukemia and cancers of the oral cavity and pharynx; esophagus; stomach; colorectum; liver; pancreas; larynx; trachea, lung, and bronchus; cervix uteri; kidney and renal pelvis; and urinary bladder) from large US prospective studies and state-specific smoking prevalence data from the Behavioral Risk Factor Surveillance System...
December 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27720534/systematic-review-on-the-fate-of-the-remnant-urothelium-after-radical-cystectomy
#19
REVIEW
Georgios Gakis, Peter C Black, Bernard H Bochner, Stephen A Boorjian, Arnulf Stenzl, George N Thalmann, Wassim Kassouf
CONTEXT: Urothelial carcinoma is considered a pan-urothelial disease. As such, the remnant urothelium in the upper urinary tract and urethra following radical cystectomy (RC) remains at risk for secondary urothelial tumors (SUTs). OBJECTIVE: To describe the incidence, diagnosis, treatment, and outcomes of patients with SUTs after RC. EVIDENCE ACQUISITION: A systematic search was conducted using PubMed database according to Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines to identify studies between 1970 and 2016 reporting on malignant diseases of the urothelium after RC for bladder cancer...
October 6, 2016: European Urology
https://www.readbyqxmd.com/read/27694174/evaluation-of-prostate-cancer-with-radiolabeled-amino-acid-analogs
#20
David M Schuster, Cristina Nanni, Stefano Fanti
Conventional imaging of prostate cancer has limitations related to the frequently indolent biology of the disease. PET is a functional imaging method that can exploit various aspects of tumor biology to enable greater detection of prostate cancer than can be provided by morphologic imaging alone. Radiotracers that are in use or under investigation for targeting salient features of prostate cancer include those directed to glucose, choline, acetate, prostate-specific membrane antigen, bombesin, and amino acids...
October 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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