keyword
MENU ▼
Read by QxMD icon Read
search

PERM

keyword
https://www.readbyqxmd.com/read/29424400/-validity-of-scales-for-the-functional-assessment-of-critically-ill-patients
#1
Marcela H Libuy, Paola Szita C, Juan Hermosilla P, Daniel Arellano S, Iván Rodríguez-Núñez, Claudio Báez R
The decrease in mortality in critical patient units led to an increase in intensive care unit acquired weakness (ICUAW), which significantly affects the functional performance and quality of life of patients. There are several scales that measure functionality in critical patients. The aim of this systematic review is to determine the criterion validity and reliability of the scales that evaluate functionality in critically ill adult patients. We considered studies in critically ill adult subjects of both genders that determined the psychometric properties of the scales that evaluate functionality...
September 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29402599/pembrolizumab-in-combination-with-radiotherapy-for-metastatic-melanoma-introducing-the-perm-trial
#2
EDITORIAL
K Yip, A Melcher, K Harrington, T Illidge, J Nobes, A Webster, D Smith, P Lorigan, P Nathan, J Larkin
No abstract text is available yet for this article.
February 2, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29384083/combining-optical-coherence-tomography-with-visual-field-data-to-rapidly-detect-disease-progression-in-glaucoma-a-diagnostic-accuracy-study
#3
David F Garway-Heath, Haogang Zhu, Qian Cheng, Katy Morgan, Chris Frost, David P Crabb, Tuan-Anh Ho, Yannis Agiomyrgiannakis
BACKGROUND: Progressive optic nerve damage in glaucoma results in vision loss, quantifiable with visual field (VF) testing. VF measurements are, however, highly variable, making identification of worsening vision ('progression') challenging. Glaucomatous optic nerve damage can also be measured with imaging techniques such as optical coherence tomography (OCT). OBJECTIVE: To compare statistical methods that combine VF and OCT data with VF-only methods to establish whether or not these allow (1) more rapid identification of glaucoma progression and (2) shorter or smaller clinical trials...
January 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29340765/orotracheal-tube-as-a%C3%A2-risk-factor-for-lower-respiratory-tract-infection-preliminary-data-from-a%C3%A2-randomised-trial
#4
Igor Muzlovic, Janja Perme, David Stubljar
PURPOSE: The aim of the study was to investigate whether polyurethane (PU) endotracheal tubes, continuous measurements of cuff pressure and aspiration of the subglottic space as a bundle of parameters could reduce patients' risk for developing ventilator associated pneumonia (VAP). METHODS: Two groups of patients that differed only in terms of endotracheal tubes and intubation intervention were compared. Group A was ventilated using PU tubes a with conical cuff; they also had continuous cuff pressure measurement and continuous subglottic aspiration...
January 16, 2018: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29331134/coarse-grained-model-of-nanoscale-segregation-water-diffusion-and-proton-transport-in-nafion-membranes
#5
Aleksey Vishnyakov, Runfang Mao, Ming-Tsung Lee, Alexander V Neimark
We present a coarse-grained model of the acid form of Nafion membrane that explicitly includes proton transport. This model is based on a soft-core bead representation of the polymer implemented into the dissipative particle dynamics (DPD) simulation framework. The proton is introduced as a separate charged bead that forms dissociable Morse bonds with water beads. Morse bond formation and breakup artificially mimics the Grotthuss hopping mechanism of proton transport. The proposed DPD model is parameterized to account for the specifics of the conformations and flexibility of the Nafion backbone and sidechains; it treats electrostatic interactions in the smeared charge approximation...
January 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29301538/hair-product-use-age-at-menarche-and-mammographic-breast-density-in-multiethnic-urban-women
#6
Jasmine A McDonald, Parisa Tehranifar, Julie D Flom, Mary Beth Terry, Tamarra James-Todd
BACKGROUND: Select hair products contain endocrine disrupting chemicals (EDCs) that may affect breast cancer risk. We hypothesize that, if EDCs are related to breast cancer risk, then they may also affect two important breast cancer risk factors: age at menarche and mammographic breast density. METHODS: In two urban female cohorts (N = 248): 1) the New York site of the National Collaborative Perinatal Project and 2) the New York City Multiethnic Breast Cancer Project, we measured childhood and adult use of hair oils, lotions, leave-in conditioners, root stimulators, perms/relaxers, and hair dyes using the same validated questionnaire...
January 4, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29282769/glial-m6b-stabilizes-the-axonal-membrane-at-peripheral-nodes-of-ranvier
#7
Marie L Bang, Anya Vainshtein, Hyun-Jeong Yang, Yael Eshed-Eisenbach, Jerome Devaux, Hauke B Werner, Elior Peles
Glycoprotein M6B and the closely related proteolipid protein regulate oligodendrocyte myelination in the central nervous system, but their role in the peripheral nervous system is less clear. Here we report that M6B is located at nodes of Ranvier in peripheral nerves where it stabilizes the nodal axolemma. We show that M6B is co-localized and associates with gliomedin at Schwann cell microvilli that are attached to the nodes. Developmental analysis of sciatic nerves, as well as of myelinating Schwann cells/dorsal root ganglion neurons cultures, revealed that M6B is already present at heminodes, which are considered the precursors of mature nodes of Ranvier...
December 28, 2017: Glia
https://www.readbyqxmd.com/read/29260772/-department-of-otorhinolaryngology-at-the-academician-e-a-vagner-perm-state-medical-university
#8
A M Elovikov
The present article was designed to describe the history of the Department of Otorhinolaryngology based at the Academician E.A. Vagner Perm State Medical University and overview its research, educational, and therapeutic activities.
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/29260746/-the-spectrum-of-primary-drug-resistance-of-mycobacterium-tuberculosis-in-patients-with-tuberculosis-in-relation-to-human-immunodeficiency-virus-status
#9
V N Zimina, O E Mikova, T A Varetskaya, D A Oborin, S Yu Degtyareva, V I Sergevnin
AIM: To estimate the detection rate and spectrum of primary drug resistance of Mycobacterium tuberculosis (MBT) in patients with tuberculosis (TB) in relation to their human immunodeficiency virus (HIV) status in a region with high HIV infection rates (the Perm Territory) and to compare of drug-resistant MBT (DR-MBT) in patients with HIV/TB co-infection, by using phenotypic and molecular genetic testing (MGT) methods. SUBJECTS AND METHODS: The results of sputum bacteriological examination were analyzed in 178 HIV-infected patients and 354 non-HIV-infected individuals with a TB diagnosis made in the period July 1, 2014 to August 1, 2015...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29205302/population-based-cancer-survival-in-the-united-states-data-quality-control-and-statistical-methods
#10
Claudia Allemani, Rhea Harewood, Christopher J Johnson, Helena Carreira, Devon Spika, Audrey Bonaventure, Kevin Ward, Hannah K Weir, Michel P Coleman
BACKGROUND: Robust comparisons of population-based cancer survival estimates require tight adherence to the study protocol, standardized quality control, appropriate life tables of background mortality, and centralized analysis. The CONCORD program established worldwide surveillance of population-based cancer survival in 2015, analyzing individual data on 26 million patients (including 10 million US patients) diagnosed between 1995 and 2009 with 1 of 10 common malignancies. METHODS: In this Cancer supplement, we analyzed data from 37 state cancer registries that participated in the second cycle of the CONCORD program (CONCORD-2), covering approximately 80% of the US population...
December 15, 2017: Cancer
https://www.readbyqxmd.com/read/29124996/a-30-year-mortality-and-respiratory-morbidity-study-of-refractory-ceramic-fiber-workers
#11
Grace LeMasters, James E Lockey, Timothy J Hilbert, Linda S Levin, Jeff W Burkle, Ralph Shipley, Charles Perme, Cristopher A Meyer, Carol H Rice
AIM: Report mortality (n = 1119), cancer incidence (n = 1207) and radiographic (n = 1451) findings from a 30-year investigation of current and former refractory ceramic fiber (RCF) workers. METHODS: Cause of death, health and work histories, radiographs and spirometry were collected. Mortality and cancer incidence were analyzed. Logistic regression analysis investigated the associations of latency and cumulative fiber exposure (CFE) on radiographic changes...
August 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29040269/elevated-blood-pressure-and-risk-of-mitral-regurgitation-a-longitudinal-cohort-study-of-5-5-million-united-kingdom-adults
#12
Kazem Rahimi, Hamid Mohseni, Catherine M Otto, Nathalie Conrad, Jenny Tran, Milad Nazarzadeh, Mark Woodward, Terence Dwyer, Stephen MacMahon
BACKGROUND: Mitral regurgitation in people without prior cardiac disease is considered a degenerative disease with no established risk factors for its prevention. We aimed to test the hypothesis that elevated systolic blood pressure (SBP) across its usual spectrum is associated with higher risk of mitral regurgitation. METHODS AND FINDINGS: We used linked electronic health records from the United Kingdom Clinical Practice Research Datalink (CPRD) from 1 January 1990 to 31 December 2015...
October 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29022078/survival-benefit-of-mantle-cell-lymphoma-patients-enrolled-in-clinical-trials-a-joint-study-from-the-lysa-group-and-french-cancer-registries
#13
Alix Augustin, Steven Le Gouill, Rémy Gressin, Aurélie Bertaut, Alain Monnereau, Anne-Sophie Woronoff, Brigitte Trétarre, Patricia Delafosse, Xavier Troussard, Anne Moreau, Olivier Hermine, Marc Maynadié
PURPOSE: Mantle cell lymphoma (MCL) is a rare non-Hodgkin's lymphoma entity with a poor prognosis. Therapeutic advances have improved the survival of patients enrolled in clinical trials; however, their impact on patients outside clinical trials remains unclear. In this work, we compared patient outcome inside and outside clinical trials. METHODS: We identified MCL patients recorded in six French population-based registries between 2008 and 2012 to perform a comparison with patients enrolled in two prospective multicenter MCL clinical trials conducted by the LYSA group during the same period...
October 11, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28968953/brip1-coding-variants-are-associated-with-a-high-risk-of-hepatocellular-carcinoma-occurrence-in-patients-with-hcv-or-hbv-related-liver-disease
#14
Abderrahim Oussalah, Patrice Hodonou Avogbe, Erwan Guyot, Céline Chery, Rosa-Maria Guéant-Rodriguez, Nathalie Ganne-Carrié, Aurélie Cobat, Darius Moradpour, Bertrand Nalpas, Francesco Negro, Thierry Poynard, Stanislas Pol, Pierre-Yves Bochud, Laurent Abel, Hélène Jeulin, Evelyne Schvoerer, Nicodème Chabi, Emile Amouzou, Ambaliou Sanni, Hélène Barraud, Pierre Rouyer, Thomas Josse, Laetitia Goffinet, Jean-Louis Jouve, Anne Minello, Claire Bonithon-Kopp, Gérard Thiefin, Vincent Di Martino, Michel Doffoël, Carine Richou, Jean-Jacques Raab, Patrick Hillon, Jean-Pierre Bronowicki, Jean-Louis Guéant
The molecular mechanisms of hepatocellular carcinoma (HCC) carcinogenesis are still not fully understood. DNA repair defects may influence HCC risk. The aim of the study was to look for potential genetic variants of DNA repair genes associated with HCC risk among patients with alcohol- or viral-induced liver disease. We performed four case-control studies on 2,006 European- (Derivation#1 and #2 studies) and African-ancestry (Validation#1 and #2 studies) patients originating from several cohorts in order to assess the association between genetic variants on DNA repair genes and HCC risk using a custom array encompassing 94 genes...
September 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28959160/selection-of-non-small-cell-lung-cancer-patients-for-intercalated-chemotherapy-and-tyrosine-kinase-inhibitors
#15
Matjaz Zwitter, Antonio Rossi, Massimo Di Maio, Maja Pohar Perme, Gilberto Lopes
BACKGROUND: When treating patients with advanced non-small cell lung cancer (NSCLC) with tyrosine kinase inhibitors and chemotherapy, intercalated schedule with time separation between the two classes of drugs should avoid their mutual antagonism. In a survey of published trials, we focus on relation between eligibility criteria and effectiveness of intercalated treatment. METHODS: Published documents were identified using major medical databases, conference proceedings and references of published trials...
September 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28943456/permethrin-pesticide-induces-nurr1-up-regulation-in-dopaminergic-cell-line-is-the-pro-oxidant-effect-involved-in-toxicant-neuronal-damage
#16
Laura Bordoni, Donatella Fedeli, Cinzia Nasuti, Melania Capitani, Dennis Fiorini, Rosita Gabbianelli
The mechanisms associated to the development of neurodegeneration due to pesticide exposure are not clear yet. In this study we evaluated how permethrin pesticide (PERM) can influence the Nurr1 gene and protein expression, and if a pro-oxidant activity of the pesticide contributes to up-regulation of Nurr1 in a dopaminergic cell line. Incubation of PC12 cells with 1μM PERM for 72h, leads to over expression of Nurr1 gene. This effect occurs with both corn oil and extra virgin olive oil (EVO) used to solubilize the toxicant...
September 22, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28921571/comparing-touch-senses-of-na%C3%A3-ve-and-expert-panels-through-treated-hair-swatches-which-associated-wordings-correlate-with-hair-physical-properties
#17
A Galliano, J Y Kempf, M Fougere, M Applebaum, L J Wolfram, H Maibach
OBJECTIVES: This study (i) compared the sense of touch between a naïve and expert panels, under visual or blind conditions, using differently treated hair swatches and (ii) explored possible common wordings used by both panels and their possible links with some physical properties of hairs. METHODS: Two sets of 15 hair swatches of Caucasian and Chinese origins were differently treated (bleached, permed, brushed, etc.) or organized (root-tip vs. tip-root). These were evaluated by tactile assessments by two panels (105 naïve consumers and 10 hair experts) under visual or blind conditions, in two geographical locations...
September 16, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28921374/prostate-cancer-clinical-presentation-incidence-mortality-and-survival-in-guadeloupe-over-the-period-2008-2013-from-a-population-based-cancer-registry
#18
J Deloumeaux, B Bhakkan, R Eyraud, F Braud, N Manip M'Ebobisse, P Blanchet, L Brureau
PURPOSE: The Caribbean population of Guadeloupe has one of the highest incidence rates of prostate cancer worldwide. In 2008, a population-based cancer registry was set up for the monitoring of cancer incidence in the aftermath of the environmental pollution with chlordecone, a persistent organochlorine insecticide formerly used in banana plantations. We describe the clinical presentation, incidence, mortality and survival of prostate cancer for the period 2008-2013. METHODS: The Guadeloupe cancer registry has been routinely collecting all incident cases of cancer since 2008...
November 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28914690/incidence-trends-and-survival-of-skin-melanoma-and-squamous-cell-carcinoma-in-cluj-county-romania
#19
Ofelia Şuteu, Mihaiela L Blaga, Florian Nicula, Patricia Şuteu, Ovidiu Coza, Patriciu Achimaş-Cadariu, Daniela Coza
The aim of this study was to determine the incidence trends of cutaneous melanoma (CM) and squamous cell carcinoma (SCC) in Cluj County, from 1998 to 2011, and the 5-year net survival between 2006 and 2010. Data on all cases of CM and SCC between 1998 and 2011 were obtained from Cluj Cancer Registry. Incidence rates were age standardized by the direct method Age Standardized Incidence Rate (ASIR), using the world standard population. Trends and annual percentage change (APC) of incidence rates were calculated by joinpoint regression analysis...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28910945/-nested-case-control-study-on-associated-factors-for-anemia-during-pregnancy
#20
C L Fan, J Y Luo, W J Gong, X Q Liu, S J Zhou, F F Zhang, J Zeng, H X Li, N Feng
Objective: To explore the related factors of anemia during pregnancy and provide scientific evidence for the primary prevention of anemia during pregnancy. Methods: The pregnant women (≤12 pregnant weeks) who received the first pregnancy care in a local medical institution in Hunan province from June 2013 to November 2014 were included in this cohort study, and for them anemia had been excluded by physical examination. Baseline survey and follow up till childbirth were conducted for them. A queue-based nested case-control study (1 ∶ 2) was conducted (380 pregnant women with anemia detected in this study as case group, 760 pregnant women without anemia randomly selected and matched by age, habitual residence during pregnancy as control group...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
keyword
keyword
116052
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"