Yeonwoo Choi, Jung-Min Ahn, Do-Yoon Kang, Hwa Jung Kim, Hoyun Kim, Jinho Lee, Mijin Kim, Jinsun Park, Kyung Won Kim, Hyun Jung Koo, Dong Hyun Yang, Seung Chai Jung, Byungjun Kim, Yiu Tung Anthony Wong, Cheung Chi Simon Lam, Wei-Hsian Yin, Jeng Wei, Yung-Tsai Lee, Hsien-Li Kao, Mao-Shin Lin, Tsung-Yu Ko, Won-Jang Kim, Se Hun Kang, Seung-Ah Lee, Dae-Hee Kim, Jae-Hong Lee, Seung-Jung Park, Duk-Woo Park
BACKGROUND: Subclinical aortic valve complex (valvular and perivalvular) thrombus is not rare after transcatheter aortic valve replacement (TAVR). The risk factors and clinical implications of these findings remain uncertain. OBJECTIVES: This study sought to evaluate the frequency, predictors, and clinical outcome of aortic valve complex thrombus after TAVR. METHODS: In the ADAPT-TAVR (Anticoagulation Versus Dual Antiplatelet Therapy for Prevention of Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement) trial comparing edoxaban vs dual antiplatelet therapy in TAVR patients without an indication for chronic anticoagulation, the frequency of valvular (subclinical leaflet thrombus) and perivalvular (supravalvular, subvalvular, and sinus of Valsalva) thrombus was evaluated by 4-dimensional computed tomography at 6 months...
December 25, 2023: JACC. Cardiovascular Interventions