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Radovan Bílek, Nataša Kaňová, Veronika Mindžáková, David Neumann, Jan Jiskra, Lydie Ryšavá, Václav Zamrazil
INTRODUCTION: Iodine deficiency is a global public health problem which is particularly noticeable in pregnant or breastfeeding women and their children. Even mild iodine deficiency during pregnancy can lead to damage to the developing brain and thus affecting the fetus intelligence, his cognitive and neurological function, embryogenesis and growth. PATIENTS: In the period 2010-2015 was determined by spectrophotometry at the Institute of Endocrinology the basal urinary iodine in 532 pregnant women at the age of 32 ± 5 (18-44) years, which came from Prague, Hradec Kralove and Mlada Boleslav...
2016: Vnitr̆ní Lékar̆ství
Tanja Kustec, Darja Keše, Irena Klavs
INTRODUCTION: To consider whether a revision of the national chlamydia surveillance system is needed, the objectives were to estimate the proportion of laboratory confirmed cases at the Institute of Microbiology and Immunology (IMI) not reported to the National Institute of Public Health (NIPH), and to assess the completeness of reporting for individual data items. METHODS: The dataset with information about the cases diagnosed at the IMI during 2007-2010, and the national chlamydia surveillance data at the NIPH, were linked using SOUNDEX code and the date of birth as unique identifier...
September 1, 2016: Zdravstveno Varstvo
Zdeněk Fryšák, David Karásek
UNLABELLED: Decrease of blood glucose levels below 3 mmol/l is in fully developed cases accompanied by neuroglycopenic symptoms that may even lead to altered state of consciousness. The treating physician frequently faces a complicated situation. This may be due to inappropriately administered drugs including cases motivated by self-harm intentions (insulin, insulin secretagogues), or alcohol abuse. Undernourished people, or those afflicted with a serious systemic infection, end-stage liver or kidney diseases or with a failing heart, belong to a risk group...
2016: Vnitr̆ní Lékar̆ství
Guðrún Mist Gunnarsdóttir, Arna Guðmundsdóttir, Per Hellman, Peter Stålberg
UNLABELLED: A previously healthy 18 year old female has repeated admissions over a six week period to the emergency department because of seizures. She has no previous history of epilepsy and denies any drug use. Imaging and electroencephalogram do not indicate epilepsy. Blood sugar levels are low on two occasions, 1.3 mmol / L and 1.7mmól / L (4.0 - 6.0 mmol / L). After further investigations the suspicion of an insulin-producing tumor arises. Extensive research and imaging is conducted to look for tumor growth without any findings...
July 2016: Læknablađiđ
Ali Lahu, Ismet H Bajraktari, Shqipdonë Lahu, Valton Saiti, Avni Kryeziu, Fadil Sherifi, Bastri Durmishi
INTRODUCTION: Reactive arthritis is an autoimmune condition which emerges as a counteraction towards an infection which has a focus elsewhere in the body. The purpose of this study is isolation of causative agents of reactive arthritis and ascertains the source of infection. The study has been carried out in the Rheumatology Clinic in Prishtina and specialized ambulance O.S. "Vendenisi-AL" in Besiana, whereas isolation of causative agents has been carried out in the National Institute for Public Health (NIPH)...
June 2016: Materia Socio-medica
D Lžičařová, J Zavadilová, M Musílek, Z Jandová, P Křížová, K Fabiánová
AIM: To perform multiple-locus variable number tandem repeat analysis (MLVA) of B. pertussis strains from the collection of the National Reference Laboratory for Diphtheria and Pertussis (NRL/DIPE), National Institute of Public Health (NIPH), Prague. The study strains were isolated from clinical specimens collected mostly in the Czech Republic over a nearly 50-year period from 1967 to 2015 (June). The isolates from three periods characterized by different vaccination strategies and trends in pertussis are compared for genetic diversity and distribution of MLVA types (MT)...
2016: Epidemiologie, Mikrobiologie, Imunologie
Klara Henderson, Dimitrios Gouglas, Laura Craw
This commentary examines the 2014 NIPH evaluation of Gavi's co-financing policy and comments on the appropriateness of the subsequent and most significant policy changes taking effect in 2016.
August 17, 2016: Vaccine
Lukana Preechasuk, Ananya Pongpaibul, Tada Kunavisarut
Non-insulinoma pancreatogeneous hypoglycemia syndrome (NIPHS) is a rare cause of hypoglycemia in adults. The cause of NIPHS is diffuse hyperinsulinism. As a result, computed tomography (CT) of pancreas, endoscopic pancreatic ultrasonography (EUS), and somatostatin receptor scintigraphy (SSRS), which are usually performed to locate an insulinoma, are not able to diagnose NIPHS. Moreover, SSRS can give a false-positive result. In this case report, we introduce a 22-year-old Thai woman who presented with fasting and postprandial hyperinsulinemic hypoglycemia...
March 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Naser Ramadani, Kreshnike Dedushi, Sefedin Muçaj, Serbeze Kabashi, Naim Jerliu, Astrit Hoxhaj
THE AIM: The aim of this paper is to analyze different factors that influence the trends of pancreatic cancer mortality and morbidity of patients treated at the UCCK of Kosovo. Within this study, we have evaluated pancreatic cancer risk factors, durability and lethality regarding Kosovan patients who have been diagnosed and treated within Kosovo. The study in question is that of retrospective research traversing the period of 2011-2015. MATERIALS AND METHODOLOGY: This retrospective research study includes 362 patients recently diagnosed with pancreatic cancer, 2011-2015 at the University Clinical Center of Kosovo in Pristina...
April 2016: Materia Socio-medica
Piotr Polański, Joanna Ostrek, Małgorzata Sadkowska-Todys
AIM: The purpose of the study is to assess the epidemiological situation of food poisonings and infections in Poland in 2013. MATERIALS AND METHODS: The evaluation was based on the analysis of information from reports of epidemiological investigations in outbreaks of food poisonings and infections, submitted by the sanitary-epidemiological stations to the Department of Epidemiology, NIZP-PZH annual bulletins (Czarkowski MP et al. "Infectious diseases and poisonings in Poland", 2006-2013...
2015: Przegla̧d Epidemiologiczny
Iwona Paradowska-Stankiewicz, Jolanta Rudowska
INTRODUCTION: The epidemiological situation of pertussis in recent years has changed dramatically. There is a high percentage of cases of pertussis among adolescents and adults. Infected adults can be a source of infection for non-immune individuals such as infants. The best strategy to prevent illness remains the implementation of vaccination in accordance with the applicable schedule. THE AIM OF THE STUDY: To assess the epidemiological situation of pertussis in Poland in 2013 in comparison to previous years and evaluation of vaccine coverage of children...
2015: Przegla̧d Epidemiologiczny
Wioletta Kmieciak, Marcin Ciszewski, Eligia M Szewczyk
The article presents an overview of diagnostics of tick-borne diseases in Poland, which form one of the most prevalent group of occupational illnesses in the Polish area. This is a current issue due to a constantly growing number of tick-borne infections, i.e., Lyme borreliosis, tick-borne encephalitis, tularemia, Q fever, human granulocytic anaplasmosis and babesiosis. The scale of the problem is well illustrated by the latest reports of the Polish National Institute of Public Health - National Institute of Hygiene (NIPH - NIH)...
2016: Medycyna Pracy
Alexandr Nemec, Lenka Radolfova-Krizova, Martina Maixnerova, Eliska Vrestiakova, Petr Jezek, Ondrej Sedo
We aimed to define the taxonomic status of 40 haemolytic and/or proteolytic strains of the genus Acinetobacter which were previously classified into five putative species termed as genomic species 14BJ (n=9), genomic species 17 (n=9), taxon 18 (n=7), taxon 19 (n=6) and taxon 20 (n=9). The strains were recovered mostly from human clinical specimens or soil and water ecosystems and were highly diverse in geographical origin and time of isolation. Comparative analysis of the rpoB and gyrB gene sequences of all strains, and the whole-genome sequences of selected strains, showed that these putative species formed five respective, well-supported clusters within a distinct clade of the genus Acinetobacter which typically, although not exclusively, encompasses strains with strong haemolytic activity...
April 2016: International Journal of Systematic and Evolutionary Microbiology
Alexander S Shashkov, Johanna J Kenyon, Sof'ya N Senchenkova, Mikhail M Shneider, Anastasiya V Popova, Nikolay P Arbatsky, Konstantin A Miroshnikov, Nikolay V Volozhantsev, Ruth M Hall, Yuriy A Knirel
Capsular polysaccharides (CPSs), from Acinetobacter baumannii isolates 1432, 4190 and NIPH 70, which have related gene content at the K locus, were examined, and the chemical structures established using 2D(1)H and(13)C NMR spectroscopy. The three isolates produce the same pentasaccharide repeat unit, which consists of 5-N-acetyl-7-N-[(S)-3-hydroxybutanoyl] (major) or 5,7-di-N-acetyl (minor) derivatives of 5,7-diamino-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic (legionaminic) acid (Leg5Ac7R), D-galactose, N-acetyl-D-galactosamine and N-acetyl-D-glucosamine...
May 2016: Glycobiology
Jennifer Nowak, Thamarai Schneiders, Harald Seifert, Paul G Higgins
Overexpression of the resistance-nodulation-cell division-type efflux pump AdeABC is often associated with multidrug resistance in Acinetobacter baumannii and has been linked to mutations in the genes encoding the AdeRS two-component system. In a previous study, we reported that the Asp20→Asn amino acid substitution in the response regulator AdeR is associated with adeB overexpression and reduced susceptibility to the antimicrobials levofloxacin, tigecycline, and trimethoprim-sulfamethoxazole. To further characterize the effect of the Asp20→Asn substitution on antimicrobial susceptibility, the expression of the efflux genes adeB, adeJ, and adeG, and substrate accumulation, four plasmid constructs [containing adeR(Asp20)S, adeR(Asn20)S, adeR(Asp20)SABC, and adeR(Asn20)SABC] were introduced into the adeRSABC-deficient A...
February 2016: Antimicrobial Agents and Chemotherapy
Pavla Škarková, Radek Kadlubiec, Michal Fischer, Jana Kratěnová, Miloš Zapletal, Jiři Vrubel
AIM: This study presents a procedure of complex assessment of the environment impact on asthma prevalence. This approach is also applicable for any other disease which is supposed to be associated with the quality of the outdoor environment. METHODS: The input data included asthma prevalence values from the National Institute of Public Health (NIPH) cross-section questionnaire survey (13,456 children) and annual reports on activities of all paediatricians in the Czech Republic (2,072 surgeries); concentrations of PM10, PM2...
September 2015: Central European Journal of Public Health
Midori Ishikawa, Kaoru Kusama, Saiko Shikanai
In Japan, the national health policy "Healthy Japan 21 (second term)" was introduced in 2013 to support prevention of lifestyle-related disease. Policy has also been recently revised on the promotion of nutrition education (shokuiku). Community-based food and nutrition actions were developed based on those policies and aimed to reinforce the linkages across the food chain, looking along its length "from field to food", including production, processing, preparation, eating and disposal. Local government is responsible for identifying the important food and nutritional problems, to devise and group effective actions on the basis of local health issues...
2015: Journal of Nutritional Science and Vitaminology
Bhavana B Rao, Benjamin Click, George Eid, Ronald A Codario
Background. Roux-en-Y gastric bypass (RYGB) is a commonly performed, effective bariatric procedure; however, rarely, complications such as postprandial hypoglycemia due to noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS) may ensue. Management of refractory NIPHS is challenging. We report a case that was successfully treated with RYGB reversal. Case Report. A 58-year-old male with history of RYGB nine months earlier for morbid obesity presented for evaluation of postprandial, hypoglycemic seizures...
2015: Case Reports in Endocrinology
Shelly Mathur, Jasmine Boparai, Sanjay N Mediwala, Jose M Garcia, Glenn R Cunningham, Marco Marcelli, Madhuri M Vasudevan
Objective. Noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS) is a disorder of endogenous hyperinsulinemia that is clinically distinguishable from insulinoma, with a greater preponderance after Roux-en-Y gastric bypass (RYBG). Hyperinsulinemic hypoglycemia can predispose to attenuation of counterregulatory hormone responses to hypoglycemia, and consequent suppression of the hypothalamic-pituitary-adrenal (HPA) axis. This case series describes 3 individuals who were diagnosed with adrenal insufficiency (AI) after undergoing RYGB, complicated by NIPHS...
January 2014: Journal of Investigative Medicine High Impact Case Reports
Scott M Thompson, Adrian Vella, Geoffrey B Thompson, Kandelaria M Rumilla, F John Service, Clive S Grant, James C Andrews
CONTEXT: In adult patients with endogenous hyperinsulinemic hypoglycemia and negative or inconclusive noninvasive imaging, insulinoma and non-insulinoma pancreatogenous hypoglycemic syndrome (NIPHS) resulting from diffuse nesidioblastosis must be considered in the differential diagnosis. It is not known whether the biochemical results of selective arterial calcium stimulation (SACST) with hepatic venous sampling can differentiate insulinoma from diffuse nesidioblastosis. OBJECTIVE: To determine the specificity of SACST with hepatic venous sampling in differentiating insulinoma from diffuse nesidioblastosis...
November 2015: Journal of Clinical Endocrinology and Metabolism
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