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penetration injury

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https://www.readbyqxmd.com/read/27906870/effectiveness-of-low-molecular-weight-heparin-versus-unfractionated-heparin-to-prevent-pulmonary-embolism-following-major-trauma-a-propensity-matched-analysis
#1
James P Byrne, William Geerts, Stephanie A Mason, David Gomez, Christopher Hoeft, Ryan Murphy, Melanie Neal, Avery B Nathens
BACKGROUND: Pulmonary embolism (PE) is a leading cause of delayed mortality in patients with severe injury. While low molecular weight heparin (LMWH) is often favored over unfractionated heparin (UH) for thromboprophylaxis, evidence is lacking to demonstrate an effect on the occurrence of PE. This study compared the effectiveness of LMWH versus UH to prevent PE in patients following major trauma. METHODS: Data for adults with severe injury who received thromboprophylaxis with LMWH or UH were derived from the American College of Surgeons Trauma Quality Improvement Program (2012-2015)...
November 30, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27906854/a-bullet-lying-next-to-the-common-carotid-artery-in-the-neck-of-a-young-boy
#2
Gülpembe Bozkurt, Meltem Esen Akpinar, Özlem Ünsal, Berna Uslu Coşkun
Penetrating neck trauma is most commonly caused by firearm discharge, and is potentially very dangerous, being associated with a high risk of mortality. A 12-year-old patient with a recent history of a gunshot wound to the neck was evaluated in detail; a bullet was located in close proximity to the left common carotid artery. Neck exploration was performed and the foreign body was removed without any complications. The management of the patient is discussed, as are contemporary approaches to the treatment of penetrating neck trauma...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27904758/penetrating-thoracic-spinal-cord-injury-with-ice-pick-extending-into-the-aorta-a-technical-note-and-review-of-the-literature
#3
Rani Nasser, Jonathan Nakhla, Saadat Sharif, Merritt Kinon, Reza Yassari
BACKGROUND: Penetrating spinal cord injuries pose a great challenge to both patients and the treating physicians. Although the overall incidence of penetrating spinal cord injury is the highest in the military, the ubiquity of guns in our society continues to make penetrating spinal cord injury prevalent in the civilian population. These types of injuries are particularly complicated because, beyond the trauma to the neural elements and supporting structures, other organs can be affected and a team approach is required for successful treatment...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27903839/the-effect-of-brain-tomography-findings-on-mortality-in-sniper-shot-head-injuries
#4
Çağdaş Can, M Bolatkale, A Sarıhan, Y Savran, A Ç Acara, M Bulut
OBJECTIVES: Penetrating gunshot head injuries have a poor prognosis and require prompt care. Brain CT is a routine component of the standard evaluation of head wounds and suspected brain injury. We aimed to investigate the effect of brain CT findings on mortality in gunshot head injury patients who were admitted to our emergency department (ED) from the Syrian Civil War. METHODS: The study group comprised patients who were admitted to the ED with gunshot brain injury...
November 30, 2016: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/27900296/outcomes-after-quadriceps-tendon-repair-in-patients-over-80-years-of-age
#5
Prasad Ellanti, Andrew Moriarty, Matthew Nagle, Tom McCarthy
BACKGROUND: Quadriceps tendon (QT) ruptures are uncommon and mostly occur in those who are 50-60 years of age. Timely surgical repair can result in a good functional outcome, however, little is known about the outcome in the older patient. METHODS: A retrospective review of all QT ruptures between 2009 and 2014 was conducted. Patients over the age of 80 were included. Those with penetrating trauma or partial ruptures were excluded. A chart review was undertaken to gather demographic and operative details...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27899393/penetrating-injury-to-the-cardiac-box-and-the-deadly-dozen
#6
Michael Nicoara, David Parizh, Vadim Meytes, Anthony Kopatsis
No abstract text is available yet for this article.
November 29, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27896450/extremity-cta-for-penetrating-trauma-10-year-experience-using-a-64-detector-row-ct-scanner
#7
Charles G Colip, Varun Gorantla, Christina A LeBedis, Jorge A Soto, Stephan W Anderson
PURPOSE: The purpose of this study is to assess the performance of CT angiography (CTA) in the evaluation of penetrating vascular trauma to the extremities in a large cohort of patients at our level I trauma center. METHODS: A retrospective, IRB-approved review of consecutive CTAs for the evaluation of penetrating trauma to the extremities in 446 patients (M/F = 396:50, mean age = 27 years) from 1/1/2005 to 5/1/2015 was performed. Medical records were reviewed to correlate diagnostic imaging findings with clinical history and subsequent interventions...
November 29, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27894433/the-role-of-minimally-invasive-surgery-in-pediatric-trauma
#8
REVIEW
Erik G Pearson, Matthew S Clifton
Minimally invasive surgery (MIS) in the management of blunt and penetrating pediatric trauma has evolved in the past 30 years. Laparoscopy and thoracoscopy possess high levels of diagnostic accuracy with low associated missed injury rates. Currently available data advocate limiting the use of MIS to blunt or penetrating injuries in the hemodynamically stable child. In the pediatric trauma population, MIS offers both diagnostic and therapeutic potential, as well as reduced postoperative pain, a decreased rate of postoperative complications, shortened hospital stay, and potentially reduced cost...
February 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27893642/comparison-of-nonoperative-and-surgial-management-of-renal-trauma-can-we-predict-when-nonoperative-management-fails
#9
Marc A Bjurlin, Richard Jacob Fantus, Richard Joseph Fantus, Dana Villines
BACKGROUND: Limited data exists on risk factors for the failure of nonoperative management of renal trauma. Our study objective was to determine the incidence, salvage procedure, and risk factors for failure of nonoperative management of renal trauma. METHODS: The National Trauma Data Bank research datasets admission year 2010 - 2014 were queried for renal injury by Abbreviated Injury Score (AIS) code. Patients were stratified by interventional therapy (renal procedure code <24 hrs from admission) and nonoperative management (no surgical renal procedure <24 hrs)...
November 23, 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27890320/trepanation-in-the-late-bronze-age-and-early-iron-age-in-armenia
#10
A Yu Khudaverdyan
In this study, trepanations in ancient Armenia are discussed. In total, 10 cases were studied. Seven were male, 1 female and 2 were children. Age of the individuals ranged from 6 to 65 years. Among nine cases of surgical trepanations four had possible healing signs. In these cases the individuals showed evidence of previous trauma to the skull or infection (mastoiditis, tuberculosis), suggesting that the operation had been carried out for therapeutic purposes. This provides further support for the suggestion that trepanation (or trephination) was performed primarily for therapeutic purposes, and because of cranial infection or injury...
October 4, 2016: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/27886952/complex-inferior-vena-cava-filter-retrieval-complicated-by-migration-of-filter-fragment-into-the-aorta-and-subsequent-distal-embolization
#11
Erica M Knavel, Michael A Woods, Mark G Kleedehn, Orhan S Ozkan, Paul F Laeseke
In 2005, a 48-year-old man with a spinal cord injury had an inferior vena cava filter placed for recurrent deep vein thrombosis and pulmonary embolism. He was referred for filter retrieval after a computed tomography scan demonstrated caval stenosis and 2 fractured filter arms, 1 in a pulmonary artery and 1 penetrating into the retroperitoneum and impinging on the aorta. During retrieval, 1 arm was inadvertently advanced into the aorta, and embolization of the arm occurred to the left profunda femoris artery...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27884321/the-role-of-computed-tomography-after-emergent-trauma-operation
#12
Kazuhide Matsushima, Kenji Inaba, Ryan Dollbaum, Desmond Khor, Vidhi Jhaveri, Omar Jimenez, Aaron Strumwasser, Demetrios Demetriades
BACKGROUND: Although computed tomography (CT) has become the preferred diagnostic modality, immediate surgical intervention is often required for severely injured patients with minimum preoperative radiographic evaluation. The utility of postoperative CT (postop-CT) for the identification of undiagnosed injuries and its impact on patient management remain unclear. The purpose of this study was to evaluate the utility of postop-CT for the identification of clinically significant injuries in patients who underwent an emergent life-saving procedure...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27881824/two-tissue-resident-progenitor-lineages-drive-distinct-phenotypes-of-heterotopic-ossification
#13
Devaveena Dey, Jana Bagarova, Sarah J Hatsell, Kelli A Armstrong, Lily Huang, Joerg Ermann, Ashley J Vonner, Yue Shen, Agustin H Mohedas, Arthur Lee, Elisabeth M W Eekhoff, Annelies van Schie, Marie B Demay, Charles Keller, Amy J Wagers, Aris N Economides, Paul B Yu
Fibrodysplasia ossificans progressiva (FOP), a congenital heterotopic ossification (HO) syndrome caused by gain-of-function mutations of bone morphogenetic protein (BMP) type I receptor ACVR1, manifests with progressive ossification of skeletal muscles, tendons, ligaments, and joints. In this disease, HO can occur in discrete flares, often triggered by injury or inflammation, or may progress incrementally without identified triggers. Mice harboring an Acvr1(R206H) knock-in allele recapitulate the phenotypic spectrum of FOP, including injury-responsive intramuscular HO and spontaneous articular, tendon, and ligament ossification...
November 23, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27881496/penetrating-intracranial-injury-caused-by-an-unusual-home-made-iron-pyrotechnic-device
#14
Slobodan Nikolić, Vladimir Živković
Herein, a potentially dangerous explosive home-made device used for fun and entertainment is described. It consists of two iron parts connected with a U-shaped thick wire: a wedge about 8 cm in length, which fits into a hollow cylinder, filled with a small amount of nitre (the mineral form of potassium nitrate). Striking the device onto a hard surface creates a spark inside it, which burns the nitre, producing a very loud bang. We are in possession of such device in our forensic museum collection. We present a case from 1937 related to the use of this explosive home-made device...
November 23, 2016: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/27879614/getting-a-better-look-outcomes-of-laparoscopic-versus-transdiaphragmatic-pericardial-window-for-penetrating-thoracoabdominal-trauma-at-a-level-i-trauma-center
#15
Jamie E Anderson, Edgardo S Salcedo, Kacie M Rounds, Joseph M Galante
BACKGROUND: In penetrating thoracoabdominal trauma, it is necessary to evaluate both the pericardial fluid and the diaphragm directly. Transdiaphragmatic pericardial windows (TDWs) provide direct access to the pericardium and diaphragm but expose the patient to the risks of laparotomy. We hypothesize that transabdominal laparoscopic pericardial windows (LPWs) are a safe and effective alternative to TDWs in stable patients. METHODS: This is a retrospective observational study of stable patients with thoracoabdominal penetrating trauma at a level I trauma center between January 2007 and June 2015, comparing outcomes after TDW versus LPW...
December 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27876619/inhibition-of-the-potassium-channel-kca3-1-by-senicapoc-reverses-tactile-allodynia-in-rats-with-peripheral-nerve-injury
#16
Roland G W Staal, Tanzilya Khayrullina, Hong Zhang, Scott Davis, Shaun M Fallon, Manuel Cajina, Megan E Nattini, Andrew Hu, Hua Zhou, Suresh Babu Poda, Stevin Zorn, Gamini Chandrasena, Elena Dale, Brian Cambpell, Lars Christian B Rønn, Gordon Munro, Thomas Mӧller
Neuropathic pain is a debilitating, chronic condition with a significant unmet need for effective treatment options. Recent studies have demonstrated that in addition to neurons, non-neuronal cells such as microglia contribute to the initiation and maintenance of allodynia in rodent models of neuropathic pain. The Ca(2+)- activated K(+) channel, KCa3.1 is critical for the activation of immune cells, including the CNS-resident microglia. In order to evaluate the role of KCa3.1 in the maintenance of mechanical allodynia following peripheral nerve injury, we used senicapoc, a stable and highly potent KCa3...
November 19, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27874147/open-globe-eye-injury-characteristics-and-prognostic-factors-in-jazan-saudi-arabia
#17
Mashaal A Makhrash, Ibrahim M Gosadi
To evaluate characteristics and prognostic factors of open globe injuries (OGI) presented to King Fahad Specialist Hospital in the Jazan region, Saudi Arabia.  Methods: This study is a retrospective review of medical records of OGI patients who underwent operative repair of their injuries in King Fahad Central Hospital, Jazan, Saudi Arabia between January 2011 and December 2013. Demographic information, eye injury, preoperative, and postoperative visual acuity were collected. The initial and final visual acuity outcomes were compared to identify subjects who witnessed any improvement in their visual acuity...
December 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27872763/effects-of-microtubule-stabilization-by-epothilone-b-depend-on-the-type-and-age-of-neurons
#18
Eun-Hae Jang, Aeri Sim, Sun-Kyoung Im, Eun-Mi Hur
Several studies have demonstrated the therapeutic potential of applying microtubule- (MT-) stabilizing agents (MSAs) that cross the blood-brain barrier to promote axon regeneration and prevent axonal dystrophy in rodent models of spinal cord injury and neurodegenerative diseases. Paradoxically, administration of MSAs, which have been widely prescribed to treat malignancies, is well known to cause debilitating peripheral neuropathy and axon degeneration. Despite the growing interest of applying MSAs to treat the injured or degenerating central nervous system (CNS), consequences of MSA exposure to neurons in the central and peripheral nervous system (PNS) have not been thoroughly investigated...
2016: Neural Plasticity
https://www.readbyqxmd.com/read/27871682/factors-affecting-mortality-after-penetrating-cardiac-injuries-10-year-experience-at-urban-level-i-trauma-center
#19
Michael J Mina, Rashi Jhunjhunwala, Rondi B Gelbard, Stacy D Dougherty, Jacquelyn S Carr, Christopher J Dente, Jeffrey M Nicholas, Amy D Wyrzykowski, Jeffrey P Salomone, Gary A Vercruysse, David V Feliciano, Bryan C Morse
BACKGROUND: Despite the lethality of injuries to the heart, optimizing factors that impact mortality for victims that do survive to reach the hospital is critical. METHODS: From 2003 to 2012, prehospital data, injury characteristics, and clinical patient factors were analyzed for victims with penetrating cardiac injuries (PCIs) at an urban, level I trauma center. RESULTS: Over the 10-year study, 80 PCI patients survived to reach the hospital...
October 15, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27871107/the-large-omnidirectional-child-lodc-atd-biofidelity-comparison-with-the-hybrid-iii-10-year-old
#20
Jason Stammen, Kevin Moorhouse, Brian Suntay, Michael Carlson, Yun-Seok Kang
When the Hybrid III 10-year old (HIII-10C) anthropomorphic test device (ATD) was adopted into Code of Federal Regulations (CFR) 49 Part 572 as the best available tool for evaluating large belt-positioning booster seats in Federal Motor Vehicle Safety Standard (FMVSS) No. 213, NHTSA stated that research activities would continue to improve the performance of the HIII-10C to address biofidelity concerns. A significant part of this effort has been NHTSA's in-house development of the Large Omnidirectional Child (LODC) ATD...
November 2016: Stapp Car Crash Journal
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