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penetration wound

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https://www.readbyqxmd.com/read/29667639/-a-change-in-the-direction-of-the-wound-channel-in-the-case-of-the-combined-injury-inflicted-by-a-shot-from-the-9-0-mm-makarov-pistol
#1
A A Gusarov, I Yu Makarov, V A Fetisov
The authors present an example from the expert practice demonstrating the influence of such factors as the properties of the ammunition fired from a weapon (including its weight, size, shape, and speed) as well as the anatomical features of the body tissues being affected on the mechanism of formation of a gunshot wound in the human body. The investigation of the suicide of subject P. has demonstrated the penetrating bullet wound of the neck and the head. The entrance wound was located at the anterior neck surface and the exit one in the left half of the occipital region...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29659947/pediatric-thoracic-trauma-in-iraq-and-afghanistan
#2
Ryan J Keneally, Cynthia H Shields, Albert Hsu, Howard I Prior, Kevin M Creamer
Introduction: The objective of this study is to review available data on pediatric thoracic trauma seen at U.S. military treatment facilities in Iraq and Afghanistan and describe the scope of injuries, patterns seen, and associated mortality. The results were compared with adults injured in Iraq and Afghanistan and other reports of pediatric thoracic trauma in the literature. Materials and Methods: The investigators received approval from the Uniformed Services University of the Health Sciences' institutional review board before the study...
April 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29644530/a-posttraumatic-pseudoaneurysm-of-the-left-radial-artery-as-a-result-of-a-stab-wound-in-an-8-year-old-girl
#3
Goran Djuricic, Zorica Milosevic, Tijana Radovic, Ivana Dasic, Djordje Alempijevic, Jelena Sopta
Pseudoaneurysms arise from a disruption of arterial wall continuity and are most commonly related to a penetrating trauma, an arterial wall inflammation or iatrogenic causes. They differ from real aneurysms due to a lack of one or more layers of the arterial wall. The frequency of peripheral artery pseudoaneurysms in the upper extremities is less than in the lower extremities and its most common cause is a gunshot or a stab wound. The risk of a rupture is higher than in true aneurysms due to a lack of wall layers, therefore requiring surgical treatment in most cases...
April 11, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29644318/radiographically-occult-perforation-and-dissection-of-the-common-carotid-artery-following-stab-injury-to-the-neck
#4
Sebastian Gamba, Mario Lachat, Hatem Alkadhi, Hans-Peter Simmen, Kai Oliver Jensen
In recent years, many diagnostic algorithms have been devised to reduce the rate of negative explorations associated with indiscriminate surgical management of penetrating neck injuries. In hemodynamically stable patients, the need for surgical intervention is usually determined by integrating both clinical signs and radiological findings; if such investigations remain unremarkable, recommended treatment consists in close observation and sequential physical examinations. We report on a 29-year-old male who was admitted to a Swiss tertiary care hospital after sustaining a penetrating injury to his left neck following a knife attack...
June 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644299/surgical-management-of-compartment-syndrome-and-the-gradual-closure-of-a-fasciotomy-wound-using-a-dermaclose-device
#5
Gregory C Manista, Andrew Dennis, Matthew Kaminsky
The immediate recognition and timely response of compartment syndrome due to damage caused by penetrating trauma has immense clinical outcomes. The following is a case report of a complicated fasciotomy in a 33-year-old male who suffered a gunshot wound to his left lower extremity and the surgical management leading to adequate limb salvage and recovery.
April 2018: Trauma Case Reports
https://www.readbyqxmd.com/read/29644266/ureteric-transection-secondary-to-penetrating-handlebar-injury
#6
K P Debbink, D B Tashjian, M V Tirabassi, R Gaffey, J Nahmias
Ureteric trauma is rare, occurring in < 1% of all traumas. We present a unique case of a 13 year old female who sustained a penetrating abdominal injury from a bicycle handlebar. Upon initial examination there was herniation of bowel through the abdominal wound, so exploratory laparotomy was performed. A serosal injury of the colon and bleeding mesenteric veins were encountered; the retroperitoneum was not explored at that time. Postoperative course was remarkable for a doubling of the serum creatinine, increasing abdominal distention and pain...
August 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29644264/laparoscopic-approach-to-the-management-of-penetrating-traumatic-diaphragmatic-injury
#7
Teo Li Tserng, Maria Benita Gatmaitan
Background: Traditionally, laparotomy/thoracotomy is the standard approach for thoracoabdominal injuries. However, it has a non-therapeutic rate of 12-40% and 40% morbidity. Laparoscopy, as a diagnostic and therapeutic modality, has evolved to be integral to general and subspecialty surgeons in the management of patients. However, its use in the field of trauma surgery has been limited. We present a case of traumatic diaphragmatic injury from a low velocity penetrating wound successfully repaired through laparoscopic approach...
August 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29643807/antimicrobial-peptides-and-their-therapeutic-potential-for-bacterial-skin-infections-and-wounds
#8
REVIEW
Anja Pfalzgraff, Klaus Brandenburg, Günther Weindl
Alarming data about increasing resistance to conventional antibiotics are reported, while at the same time the development of new antibiotics is stagnating. Skin and soft tissue infections (SSTIs) are mainly caused by the so called ESKAPE pathogens ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa , and Enterobacter species) which belong to the most recalcitrant bacteria and are resistant to almost all common antibiotics. S. aureus and P. aeruginosa are the most frequent pathogens isolated from chronic wounds and increasing resistance to topical antibiotics has become a major issue...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29625989/a-cell-penetrating-peptide-fused-phage-lysin-kills-intracellular-mrsa-in-keratinocytes-and-treatment-for-skin-infections-of-mice
#9
ZhaoFei Wang, LiCheng Kong, Yang Liu, Qiang Fu, ZeLin Cui, Jian Wang, JingJiao Ma, HengAn Wang, YaXian Yan, JianHe Sun
Staphylococcus aureus ( S. aureus ) is the major pathogen that causes skin and skin structure infections, which is able to survive and persist in keratinocytes of the epidermis. Since the evolution of multi-drug resistant bacteria, the use of phages and their lysins presents a promising alternative approach. In this study, a cell wall hydrolase (also called lysin) derived from Staphylococcus phage JD007, short for JDlys, was identified. The JDlys showed a strong lytic activity against MRSA strains from different sources and multilocus sequence typing (MLST) types...
April 6, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29617508/the-role-of-heart-team-approach-in-penetrating-cardiac-trauma-case-report-and-review-of-the-literature
#10
Marzia Cottini, Amedeo Pergolini, Federico Ranocchi, Francesco Musumeci
Penetrating cardiac trauma has been increasing in clinical experience and is joined to important morbidity and mortality. A case of a 38-year-old female with history of postpartum depression was reported, admitted to our department for cardiac tamponade due to penetrating self-inflicted multiple stab wound of the chest complicated by rupture of anterior left ventricular wall and traumatic ventricular septal defect. Following the unstable hemodynamic instability, a combined therapeutic strategy was chosen: surgery and transcatheter implantation to correct free wall ventricle damage and traumatic ventricular septal defect, respectively...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29614369/candida-parapsilosis-isolates-from-burn-wounds-can-penetrate-an-acellular-dermal-matrix
#11
Erika Okuno, Isabele Carrilho Jarros, Patricia Souza Bonfim-Mendonça, Glória Vicente de Rezende, Melyssa Negri, Terezinha Estivalet Svidzinski
We isolated and identified yeasts from burn wounds and evaluated the ability of Candida parapsilosis isolates from burn wounds to penetrate an acellular dermal matrix (ADM). A prospective study was conducted with patients from the burn treatment center of North Paraná University Hospital in Londrina, Brazil from February 2015 to January 2016. Yeast cultures were obtained from the tissue of burn wounds that had been debrided and cleansed with 2% chlorhexidine. After identification and confirmation of the purity of the culture, the yeasts were placed on ADM fragments and incubated for three or seven days...
March 31, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29613947/nationwide-trends-in-mortality-following-penetrating-trauma-are-we-up-for-the-challenge
#12
Joseph V Sakran, Ambar Mehta, Ryan Fransman, Avery B Nathens, Bellal Joseph, Alistair Kent, Elliott R Haut, David T Efron
OBJECTIVES: Despite a focus on improved pre-hospital care, penetrating injuries contribute substantially to trauma mortality in the United States (U.S.). We therefore analyzed contemporary trends in pre-hospital mortality from penetrating trauma in the past decade. METHODS: We identified patients in the The National Trauma Data Bank from 2007-2010 ('early period') and 2011-2014 ('late period') with gunshot (GSW) and stab wounds (SW), who were treated at hospitals that recorded dead-on-arrival statistics...
April 3, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29605023/a-subgroup-analysis-of-penetrating-injuries-to-the-pancreas-777-patients-from-the-national-trauma-data-bank-2010-2014
#13
Bradley Phillips, Lauren Turco, Dan McDonald, Elizabeth Mause, Ryan W Walters
BACKGROUND: This study is the first to analyze penetrating injuries to the pancreas within subgroups of severe traumatic brain injury (TBI), early deaths, and potential survivors. Our objectives were to identify national patterns of injury, predictors of mortality, and to validate the American Association for Surgery of Trauma Organ Injury Scale (AAST-OIS) pancreas injury grades by mortality. Secondary outcomes included hospital and intensive care unit length of stay and days on mechanical ventilation...
May 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29602152/how-to-recognize-the-traces-left-on-a-crime-scene-by-a-3d-printed-liberator-part-1-discharge-exterior-ballistic-and-wounding-potential
#14
Hanna Honsberger, Damien Rhumorbarbe, Denis Werner, Fabiano Riva, Matthieu Glardon, Alain Gallusser, Olivier Delémont
The Liberator is a firearm that can be manufactured from its blueprints, using a 3D-printer. This weapon made of nineteen pieces - eighteen in printed plastic and one metallic nail - raises questions such as its ability to fire a round, its wounding potential and the traces produced by its discharge. In particular, knowledge must be gained to infer that a 3D-printed handgun was used, reconstruct the shooting event involving such handgun, and gather information related to the type of 3D-printed handgun used...
March 20, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29598788/gene-silencing-of-heparanase-results-in-suppression-of-invasion-and-migration-of-gallbladder-carcinoma-cells
#15
Hao Jin, Min Cui
This study investigated the effect of transcriptional gene silencing of the heparanase gene on standard gallbladder carcinoma cells (GBC-SD). The miRNAs targeting the promoter region and coding region of the heparanase gene were designed and synthesized. We transfected four recombinant miRNA vectors into GBC-SD. We performed the wound healing assays and invasion assays. The result shows that the heparanase expression was significantly decreased by recombinant vectors in transfected GBC-SD cells (p < 0...
March 29, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29594359/-vascular-surgical-training-concept-for-military-surgeons-in-germany
#16
REVIEW
M Engelhardt, K Elias, B Friemert, K Klemm, C Willy
BACKGROUND: Due to the increasing threat of terrorist attacks and assassinations even in Europe, the interest in management of severe vascular injuries, which, with an increased incidence of 10% are to be expected with such penetrating wounds, is also growing; however, with increasing subspecialization in surgery there is a threat that the know-how in vascular surgery will become lost among non-vascular surgical specialists. Therefore, the Germany military established an educational program, the so-called DUOplus concept, to ensure that future military surgeons acquire and retain the experience and skills to fulfill the demanding role of a deployed surgeon...
March 28, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29589085/real-time-computerised-tomography-assisted-porous-tantalum-implant-in-arco-stage-i-ii-non-traumatic-osteonecrosis-of-the-femoral-head-minimum-five-year-follow-up
#17
Ruyin Hu, Pengfei Lei, Bo Li, Hao Liu, Xucheng Yang, Ting Wen, Yihe Hu, Xiaobin Tian
PURPOSES: This study was established to investigate the medium-term clinical effect of real-time CT assisted porous tantalum implant for the treatment of ARCO stage I-II non-traumatic osteonecrosis of the femoral head (ONFH). METHODS: This study comprised 24 ONFH patients (29 hips) who were treated with intra-operative real-time CT accurate rapid positioning assisted drilling decompression, lesion removal and porous tantalum implant. Harris score, VAS score and imaging in pre-operation and follow-up period were recorded...
March 27, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29583119/management-of-intra-abdominal-vascular-injury-in-trauma-laparotomy-a-south-african-experience
#18
Ross Weale, Victor Kong, Vassil Manchev, Wanda Bekker, George Oosthuizen, Petra Brysiewicz, Grant Laing, John Bruce, Damian Clarke
BACKGROUND: Intra-abdominal vascular injury (IAVI) is uncommon but continues to be associated with high mortality rates despite technological advances in the past decades. In light of these ongoing developments, we reviewed our contemporary experience with IAVI in an attempt to clarify and refine our management strategies and the outcome of these patients. METHODS: We retrospectively reviewed the charts of all patients admitted between January 2011 and December 2014 at a major trauma centre in South Africa who were found to have an IAVI during laparotomy for trauma...
April 1, 2018: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/29580233/oligohistidine-and-targeting-peptide-functionalized-tat-nls-for-enhancing-cellular-uptake-and-promoting-angiogenesis-in-vivo
#19
Qian Li, Xuefang Hao, Syed Saqib Ali Zaidi, Jintang Guo, Xiangkui Ren, Changcan Shi, Wencheng Zhang, Yakai Feng
BACKGROUND: Gene therapy has been developed and used in medical treatment for many years, especially for the enhancement of endothelialization and angiogenesis. But slow endosomal escape rate is still one of the major barriers to successful gene delivery. In order to evaluate whether introducing oligohistidine (Hn ) sequence into gene carriers can promote endosomal escape and gene transfection or not, we designed and synthesized Arg-Glu-Asp-Val (REDV) peptide functionalized TAT-NLS-Hn (TAT: typical cell-penetrating peptide, NLS: nuclear localization signals, Hn : oligohistidine sequence, n: 4, 8 and 12) peptides with different Hn sequence lengths...
March 26, 2018: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/29579354/penetrating-head-injuries-in-children-presenting-to-the-emergency-department-in-australia-and-new-zealand-a-predict-prospective-study
#20
Franz E Babl, Mark D Lyttle, Silvia Bressan, Meredith L Borland, Natalie Phillips, Amit Kochar, Sarah Dalton, John A Cheek, Yuri Gilhotra, Jeremy Furyk, Jocelyn Neutze, Susan Donath, Stephen Hearps, Marta Arpone, Louise Crowe, Stuart R Dalziel, Ruth Barker, Ed Oakley
AIM: Penetrating head injuries (pHIs) are associated with high morbidity and mortality. Data on pHIs in children outside North America are limited. We describe the mechanism of injuries, neuroimaging findings, neurosurgery and mortality for pHIs in Australia and New Zealand. METHODS: This was a planned secondary analysis of a prospective observational study of children <18 years who presented with a head injury of any severity at any of 10 predominantly paediatric Australian/New Zealand emergency departments (EDs) between 2011 and 2014...
March 26, 2018: Journal of Paediatrics and Child Health
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