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https://www.readbyqxmd.com/read/28816601/stomate-based-defense-and-environmental-cues
#1
Shweta Panchal, Maeli Melotto
Environmental conditions play crucial roles in modulating immunity and disease in plants. For instance, many bacterial disease outbreaks occur after periods of high humidity and rain. A critical step in bacterial infection is entry into the plant interior through wounds or natural openings, such as stomata. Bacterium-triggered stomatal closure is an integral part of the plant immune response to reduce pathogen invasion. Recently, we found that high humidity compromises stomatal defense, which is accompanied by regulation of the salicylic acid and jasmonic acid pathways in guard cells...
August 17, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28814248/pediatric-abdominal-trauma
#2
Tim Lynch
Abdominal trauma is present in approximately 25% of pediatric patients with major trauma and is the most common cause of unrecognized fatal injury in children. Pediatric abdominal trauma is typically blunt in nature with the spleen being the most common organ injured. Non-operative management is employed in over 95% of patients. Penetrating injuries are less common but often require operative management. Knowledge of specific mechanisms of injury aids the clinician in the diagnosis of specific injuries. Computed tomography (CT) is the gold standard in the identification of intra-abdominal injury...
August 14, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28810875/role-of-iqgap3-in-metastasis-and-epithelial-mesenchymal-transition-in-human-hepatocellular-carcinoma
#3
Yongjie Shi, Nan Qin, Qiang Zhou, Yanqiu Chen, Sicong Huang, Bo Chen, Gang Shen, Hongyun Jia
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide owing to its high rates of metastasis and recurrence. The oncogene IQ motif-containing GTPase activating protein 3 (IQGAP3) is ubiquitously overexpressed in several human cancers, including liver, ovary, lung, large intestine, gastric, bone marrow, and breast malignancies and is involved in the invasion and metastasis of cancer cells. Therefore, we aimed to determine the biological role and molecular mechanism of IQGAP3 in HCC...
August 15, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28807080/a-descriptive-analysis-of-traction-splint-utilization-and-iv-analgesia-by-emergency-medical-services
#4
Joshua Nackenson, Amado A Baez, Jonathan P Meizoso
Study Objectives Traction splinting has been the prehospital treatment of midshaft femur fracture as early as the battlefield of the First World War (1914-1918). This study is the assessment of these injuries and the utilization of a traction splint (TS) in blunt and penetrating trauma, as well as intravenous (IV) analgesia utilization by Emergency Medical Services (EMS) in Miami, Florida (USA). METHODS: This is a retrospective study of patients who sustained a midshaft femur fracture in the absence of multiple other severe injuries or severe physiologic derangement, as defined by an injury severity score (ISS) <20 and a triage revised trauma score (T-RTS)≥10, who presented to an urban, Level 1 trauma center between September 2008 and September 2013...
August 15, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28797552/perforating-cervical-thoracic-and-abdominal-wounds
#5
REVIEW
Marije Risselada
Most body wall injuries in small animals are caused by bite wounds or vehicular trauma. Penetrating gunshot wounds are less common. Bite wounds are characterized by massive trauma to the body wall with associated defects, but fewer internal injuries, whereas gunshot wounds are associated with a high number of internal injuries. Vehicular accident injuries are caused by blunt force trauma and can lead to both body wall defects and internal organ damage. Impalement injuries are rare and are typically associated with internal damage...
August 7, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28790214/-transoral-penetrating-cranial-injury-by-a-chopstick-a-case-report
#6
Kazue Fujiwara, Fumihiro Hiraoka, Yasunobu Nakamura, Masahiko Murao, Kazuo Hanakawa, Takafumi Ide
Intracranial injury resultant from a chopstick penetrating the oral cavity is often fatal in children, and only 5 clinical cases have been reported. If the depth of penetration is indeterminable, due to the chopstick being removed or the remaining piece not being located, then injury management is challenging; here, we report such a case. A 26-month-old girl fell over with a plastic chopstick in her mouth. The chopstick was removed immediately and without breakage by her father. He noted that around 3 cm of the pointed end had pierced the palate...
August 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28781920/delayed-presentation-of-spinal-foreign-body-case-report-and-review-of-literature
#7
Franz J Onishi, Mirto N Prandini, Sergio Cavalheiro
BACKGROUND: Although spinal cord injuries are frequent causes of myelopathy in young patients, stab wounds of the spinal cord rarely occur and are typically maximal symptomatic immediately after the trauma. CASE DESCRIPTION: A 31-year-old male developed delayed onset of symptoms 4 years after a stab wound to the cervical spinal cord attributed to a plant needle (plant called Mandacaru). Following removal of the foreign body and decompression/excision of scarring at the C34 level, the patient's symptoms resolved...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28769999/non-operative-management-for-penetrating-splenic-trauma-how-far-can-we-go-to-save-splenic-function
#8
Roy Spijkerman, Michel Paul Johan Teuben, Fatima Hoosain, Liezel Phyllis Taylor, Timothy Craig Hardcastle, Taco Johan Blokhuis, Brian Leigh Warren, Luke Petrus Hendrikus Leenen
BACKGROUND: Selective non-operative management (NOM) for the treatment of blunt splenic trauma is safe. Currently, the feasibility of selective NOM for penetrating splenic injury (PSI) is unclear. Unfortunately, little is known about the success rate of spleen-preserving surgical procedures. The aim of this study was to investigate the outcome of selective NOM for penetrating splenic injuries. METHODS: A dual-centre study is performed in two level-one trauma centres...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28760404/retinal-toxicity-after-accidental-intravitreal-injection-of-mepivacaine-and-adrenaline
#9
F López-Herrero, J L Sánchez-Vicente, J Monge-Esquivel, E Parra-Oviedo, A Martínez-Borrego, A Muñoz-Morales
CASE REPORT: The case is presented of a 32 year-old male with no medical history of interest who suffered a traffic accident with mild traumatic brain injury. He had a left supraciliary incised and contused wound that extended to the left upper eyelid, with no loss of vision. After palpebral anaesthetic injection, there was a sudden visual acuity decrease in the left eye and hyposphagma located between I-III at 4mm from the limbus, with increased intraocular pressure. A whitish lesion with a central haemorrhagic focus was observed in the ocular fundus, corresponding to the area where the hyposphagma was located...
July 28, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28759541/traumatic-ventricular-septal-defect-after-stab-wound-to-the-chest-missed-by-transthoracic-echocardiography-a-case-report
#10
Abimbola O Faloye, Raphael Y Gershon
Traumatic ventral septal defect may be sustained after either blunt force or penetrating trauma to the chest. Severity ranges from asymptomatic to acute decompensated heart failure. Our patient suffered a stab wound to the chest and was initially taken to the operating room for repair of a lacerated right ventricle. Subsequent postoperative hemodynamic deterioration prompted a bedside transthoracic echocardiogram, which failed to identify causal factors. A transesophageal echocardiogram performed immediately after ventral septal defect was demonstrated...
August 1, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28757422/combined-antibacterial-tissue-regeneration-response-in-thermal-burns-promoted-by-functional-chitosan-silver-nanocomposites
#11
E Luna-Hernández, M E Cruz-Soto, F Padilla-Vaca, R A Mauricio-Sánchez, D Ramirez-Wong, R Muñoz, L Granados-López, L R Ovalle-Flores, J L Menchaca-Arredondo, A Hernández-Rangel, E Prokhorov, J L García-Rivas, B L España-Sánchez, G Luna-Bárcenas
We report the combined antibacterial/tissue regeneration responses to thermal burns promoted by functional chitosan/silver nanocomposites (CS/nAg) with ultralow silver content (0.018wt.%, 7-30nm). Our approach allows one to produce CS/nAg nanocomposites without silver nanoparticles (nAg) agglomeration, with bactericide potency higher than 1wt.% of nAg (ca. 10nm) content and, promoting the healing process in controlled thermal burns. CS/nAg films exhibit high antibacterial activity against S. aureus and P. aeruginosa after 1...
July 28, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28748419/can-we-train-military-surgeons-in-a-civilian-trauma-center
#12
H Uchino, V Y Kong, G V Oosthuizen, J L Bruce, W Bekker, G L Laing, D L Clarke
INTRODUCTION: The objective of this study was to review the trauma workload and operative exposure in a major South African trauma center and provide a comparison with contemporary experience from major military conflict. MATERIALS AND METHODS: All patients admitted to the PMTS following trauma were identified from the HEMR. Basic demographic data including mechanism of injury and body region injured were reviewed. All operative procedures were categorized. The total operative volume was compared with those available from contemporary literature documenting experience from military conflict in Afghanistan...
July 26, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28732899/in-situ-reduction-of-silver-nanoparticles-by-chitosan-l-glutamic-acid-hyaluronic-acid-enhancing-antimicrobial-and-wound-healing-activity
#13
Bitao Lu, Fei Lu, Yini Zou, Jiawei Liu, Bao Rong, Zhiquan Li, Fangying Dai, Dayang Wu, Guangqian Lan
Spongy composites with silver nanoparticles (AgNPs) were synthesized by freeze-drying a mixture of silver nitrate (AgNO3) and chitosan-l-glutamic acid (CG) derivative loaded with hyaluronic acid (HA) solution. CG/AgNP spongy composites had an interconnected porous structure and rough surfaces. When AgNPs (5-20nm) were immobilized on these spongy composites, AgNP aggregation was dependent on AgNO3 concentration. The spongy composites exhibited good mechanical properties, swelling, and water retention capacity...
October 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28724890/centrosomal-protein-55-activates-nf-%C3%AE%C2%BAb-signalling-and-promotes-pancreatic-cancer-cells-aggressiveness
#14
Tao Peng, Wei Zhou, Feng Guo, He-Shui Wu, Chun-You Wang, Li Wang, Zhi-Yong Yang
Centrosomal protein 55 (CEP55) is a microtubule-bundling protein that participants in cell mitosis. It is overexpressed in several solid tumours and promotes the growth and invasion of cancer cells. However, the role of CEP55 in pancreatic cancer (PANC) remains unclear. Herein, upregulated expression of CEP55 (associated with poor prognosis) was detected in PANC using quantitative real-time reverse transcription PCR, western blotting, and immunohistochemistry. Cell migration, colony formation, wound-healing, and Transwell matrix penetration assays, revealed that upregulation of CEP55 promoted PANC cells proliferation, migration, and invasion in vitro, whereas knockdown of CEP55 attenuated it...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724813/correlation-between-the-graft-host-junction-of-penetrating-keratoplasty-by-anterior-segment-optical-coherence-tomography-and-the-magnitude-of-postoperative-astigmatism
#15
Ghada Azab Nassar, Shaimaa Abd El Salam Arfeen
PURPOSE: This study aimed to evaluate the alignment pattern of the graft-host junction after penetrating keratoplasty (PK) by anterior segment-optical coherence tomography (AS-OCT) and to correlate this pattern with the magnitude of postoperative astigmatism. METHODS: This retrospective observational study was carried out on forty patients who underwent PK from February 2013 to August 2014. AS-OCT was performed, and the graft-host junctions were classified into well-apposed junction, malapposed junction, and equally apposed junction...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28717964/wound-morphology-in-contact-shots-from-blank-cartridge-handguns-a-study-on-composite-models
#16
Rebecca Pircher, Markus Große Perdekamp, Annette Thierauf-Emberger, Lena Kramer, Stefan Pollak, Dorothee Geisenberger
It is a well-known fact that blank cartridge guns can cause penetrating and even fatal injuries when discharged in contact or at very close ranges. In these cases, the gas jet perforates the skin leaving an entrance wound similar to that from a conventional gun. In order to investigate the wound morphology in contact shots from blank firearms, test shots were fired at composite models of pig skin and gelatin blocks using three different calibre 9-mm blank cartridge handguns (two pistols and one revolver) and two types of ammunition...
July 17, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28714284/egg-albumen-as-a-fast-and-strong-medical-adhesive-glue
#17
Kaige Xu, Yuqing Liu, Shousan Bu, Tianyi Wu, Qiang Chang, Gurankit Singh, Xiaojian Cao, Chuang Deng, Bingyun Li, Gaoxing Luo, Malcolm Xing
Sutures penetrate tissues to close wounds. This process leads to inflammatory responses, prolongs healing time, and increases operation complexity. It becomes even worse when sutures are applied to stress-sensitive and fragile tissues. By bonding tissues via forming covalent bonds, some medical adhesives are not convenient to be used by surgeons and have side effects to the tissues. Here egg albumen adhesive (EAA) is reported with ultrahigh adhesive strength to bond various types of materials and can be easily used without any chemical and physical modifications...
July 17, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28709823/intracardiac-foreign-body-resulting-from-a%C3%A2-transmediastinal-gunshot-mimics-an-extracardiac-foreign-body-an-image-presentation
#18
Hsun-Yi Fu, Mao Ting, Yi-Chia Wang, Hsi-Yu Yu
A transmediastinal gunshot wound (TMGW) is one of the most severe traumatic injuries, with a high mortality rate. Prompt diagnosis and emergency surgical intervention with or without cardiopulmonary bypass are usually required to save lives. We report a particular case of TMGW in which the computed tomography imaging findings indicated an extracardiac foreign body. However, intraoperative findings revealed an intracardiac foreign body, and urgent cardiopulmonary bypass was performed to remove the foreign body...
July 11, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28706766/a-case-based-review-of-the-management-of-penetrating-brain-trauma
#19
Jason Milton, Alex Rugino, Kailash Narayan, Chris Karas, Victor Awuor
Principles of penetrating head trauma management were established by Harvey Cushing in relation to the management of penetrating brain injuries of World War One. Cushing radically debrided the scalp and skull and aggressively irrigated wound tracks to remove foreign bodies. He would then obtain water-tight closure. Cushing significantly decreased infection rates which reportedly limited the major cause of mortality due to penetrating head injuries. Many advances have been made by contributions from World War Two, Korean War, Vietnam War, and Iran/Iraq conflicts...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28705774/american-spinal-injury-association-a-sensory-and-motor-complete-is-not-different-from-american-spinal-injury-association-b-sensory-incomplete-motor-complete-in-gunshot-related-spinal-cord-injury
#20
Eric McCoy, Nima Eftekhary, Kenneth Nwosu, Dudley Fukunaga, Charles Liu, Kevin Rolfe
BACKGROUND CONTEXT: We receive a large number of patients with spinal cord injury (SCI) due to penetrating gunshot wounds (GSW) at our national rehabilitation center. Although many patients are labeled American Spinal Injury Association (ASIA) B sensory incomplete because of sensory sparing, especially deep anal pressure, with purported prognostic value, we have not observed a clinical difference from patients labeled ASIA A complete. We hypothesized that sensory sparing, if meaningful, should reduce the occurrence of pressure ulcers...
July 10, 2017: Spine Journal: Official Journal of the North American Spine Society
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