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https://www.readbyqxmd.com/read/29443759/a-traumatic-hepatic-artery-pseudoaneurysm-and-arterioportal-fistula-with-severe-diarrhea-as-the-first-symptom-a-case-report-and-review-of-the-literature
#1
Ping Han, Lan Yang, Xiao-Wei Huang, Xiu-Qin Zhu, Li Chen, Nan Wang, Zhen Li, De-An Tian, Hua Qin
RATIONALE: Hepaticarterioportal fistula (APF) is a rare cause of portal hypertension and gastrointestinal hemorrhage, and presents as abnormal communication between the hepatic artery and portal vein. Percutaneous liver biopsy is a main iatrogenic cause of AFP. However, non-iatrogenic, abdominal, trauma-related APF is rarely reported. PATIENT CONCERNS: A 29-year-old man presenting with severe, watery diarrhea was transferred to our hospital, and his condition was suspected to be acute gastroenteritis because he ate expired food and suffered a penetrating abdominal stab wound 5 years ago...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29434169/different-patterns-in-abdominal-stab-wound-in-the-self-inflicted-and-assaulted-patients-an-observational-analysis-of-single-center-experience
#2
Takeshi Nishimura, Hiroyuki Sakata, Taihei Yamada, Mariko Terashima, Kunihiro Shirai, Isamu Yamada, Joji Kotani
Patterns of penetrating abdominal stab wounds (ASW) may be different according to the mechanism of injury. The purpose of this study was to review and characterize penetrating abdominal stab wounds in self-inflicted wound patients and assaulted patients. We retrospectively analyzed patients with ASW who were admitted to our emergency department from 2007 to 2015. The patients were divided into two groups: self-inflicted wound group and assaulted group. There were 46 stabbing cases in 45 different patients (25 males, 21 females; average age 47 y, range 21 to 85 y)...
July 20, 2017: Kobe Journal of Medical Sciences
https://www.readbyqxmd.com/read/29433538/microrna-193a-stimulates-pancreatic-cancer-cell-repopulation-and-metastasis-through-modulating-tgf-%C3%AE-2-tgf-%C3%AE-riii-signalings
#3
Chi Fang, Chen-Yun Dai, Zhu Mei, Ming-Jie Jiang, Dian-Na Gu, Qian Huang, Ling Tian
BACKGROUND: Pancreatic cancer characterizes high recurrence and poor prognosis. In clinical practice, radiotherapy is widely used for pancreatic cancer treatment. However, the outcome remains undesirable due to tumor repopulation and following recurrence and metastasis after radiation. So, it is highly needed to explore the underlying molecular mechanisms and accordingly develop therapeutic strategies. Our previous studies revealed that dying cells from chemoradiation could stimulate repopulation of surviving pancreatic cancer cells...
February 13, 2018: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/29425720/nanoengineered-injectable-hydrogels-from-kappa-carrageenan-and-two-dimensional-nanosilicates-for-wound-healing-application
#4
Giriraj Lokhande, James K Carrow, Teena Thakur, Janet R Xavier, Madasamy Parani, Kayla J Bayless, Akhilesh K Gaharwar
We report injectable nanoengineered hemostats for enhanced wound healing and tissue regeneration. The nanoengineered system consists of the natural polysaccharide, κ-carrageenan (κCA), loaded with bioactive two-dimensional (2D) nanosilicates. Nanoengineered hydrogels showed shear-thinning characteristics and can be injected for a minimally invasive approach. The hydrogel can be physically crosslinked in presence of monovalent ions and result in mechanically strong hydrogels. By controlling the ratio between κCA and nanosilicates, compressive stiffness of nanoengineered hydrogels can be modulated between 20 to 200kPa...
February 6, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29413211/gastrointestinal-traumatic-injuries-gastrointestinal-perforation
#5
REVIEW
Maria A Revell, Marcia A Pugh, Melanie McGhee
The abdomen is a big place even in a small person. Gastrointestinal trauma can result in injury to the stomach, small bowel, colon, or rectum. Traumatic causes include blunt or penetrating trauma, such as gunshot wounds, stabbings, motor vehicle collisions, and crush injuries. Nontraumatic causes include appendicitis, Crohn disease, cancer, diverticulitis, ulcerative colitis, blockage of the bowel, and chemotherapy. The mechanism of injury will affect both the nature and severity of any resulting injuries. Treatment must address the critical and emergent nature of these injuries as well as issues that affect all trauma situations, which include management of hemodynamic instability...
March 2018: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29412018/single-contrast-ct-for-detecting-bowel-injuries-in-penetrating-abdominopelvic-trauma
#6
Hamza Jawad, Constantine Raptis, Aaron Mintz, Douglas Schuerer, Vincent Mellnick
OBJECTIVE: Many centers advocate use of triple-contrast (IV, oral, and rectal) CT for assessing hemodynamically stable patients with penetrating abdominopelvic trauma. Enteric contrast material has several disadvantages, leading our practice to pursue use of single-contrast (IV) CT. We conducted a retrospective review of electronic medical records at our institution to assess the accuracy of single-contrast CT for diagnosing bowel injuries in cases of penetrating abdominopelvic trauma...
February 7, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29410701/is-case-triaging-a-useful-tool-for-emergency-surgeries-a-review-of-106-trauma-surgery-cases-at-a-level-1-trauma-center-in-south-africa
#7
Sharfuddin Chowdhury, Andrew John Nicol, Mahammed Riyaad Moydien, Pradeep Harkison Navsaria, Luis Felipe Montoya-Pelaez
Background: The optimal timing for emergency surgical interventions and implementation of protocols for trauma surgery is insufficient in the literature. The Groote Schuur emergency surgery triage (GSEST) system, based on Cape Triaging Score (CTS), is followed at Groote Schuur Hospital (GSH) for triaging emergency surgical cases including trauma cases. The study aimed to look at the effect of delay in surgery after scheduling based on the GSEST system has an impact on outcome in terms of postoperative complications and death...
2018: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/29401652/establishment-success-of-the-beetle-tapeworm-hymenolepis-diminuta-depends-on-dose-and-host-body-condition
#8
Suraj Dhakal, Sebastian Micki Buss, Elizabeth Jane Cassidy, Nicolai Vitt Meyling, Brian Lund Fredensborg
Parasite effects on host fitness and immunology are often intensity-dependent. Unfortunately, only few experimental studies on insect-parasite interactions attempt to control the level of infection, which may contribute substantial variation to the fitness or immunological parameters of interest. The tapeworm Hymenolepis diminuta-flour beetle Tenebrio molitor model-has been used extensively for ecological and evolutionary host-parasite studies. Successful establishment of H. diminuta cysticercoids in T. molitor relies on ingestion of viable eggs and penetration of the gut wall by the onchosphere...
February 3, 2018: Insects
https://www.readbyqxmd.com/read/29401110/autopsy-case-of-a-penetrating-wound-to-the-left-cerebral-hemisphere-caused-by-an-accidental-shooting-with-a-crossbow
#9
Takeshi Kondo, Motonori Takahashi, Azumi Kuse, Mai Morichika, Kanako Nakagawa, Yoshihiro Tagawa, Tomoya Taniguchi, Yuji Taguchi, Tomohiro Fujiwara, Junpei Tsuchiya, Masahiko Nakamura, Makoto Sakurada, Migiwa Asano, Yasuhiro Ueno
A crossbow is a bow that shoots an arrow when a gun-like trigger is pulled. Deaths caused by accidental crossbow shootings are extremely rare. Here we describe an autopsy case of a penetrating wound to the left cerebral hemisphere caused by an accidental shooting with a crossbow. A man in his early 60s who lived with his wife and had used crossbows for 20 years as his hobby was found one early morning in the shed of his house, collapsed and bleeding from the head and neck. He was taken to a hospital and died after approximately 3 days of conservative treatment...
February 2, 2018: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29399170/mir-133b-induces-chemoresistance-of-osteosarcoma-cells-to-cisplatin-treatment-by-promoting-cell-death-migration-and-invasion
#10
Yonggen Zou, Jiexiang Yang, Jian Wu, Cheng Luo, Yuanshuai Huang
As an important chemotherapeutic agent for the treatment of osteosarcoma, the effectiveness of cisplatin is considered to be due to its unique properties, which allow it to penetrate the cell membrane and form various DNA-platinum adducts, resulting in genetic alterations or DNA damage. However, chemoresistance to cisplatin remains a major challenge for its use and chemotherapeutic effects. In the present study, an isogenic model of a cisplatin resistant osteosarcoma cell line, MG63-DDP, was generated from the original MG63 cell line...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29398037/the-national-trauma-data-bank-story-for-emergency-department-thoracotomy-how-old-is-too-old
#11
Lindsay A Gil, Michael J Anstadt, Anai N Kothari, Michael J Javorski, Richard P Gonzalez, Fred A Luchette
BACKGROUND: The fastest growing segment of the American population is the elderly (>65 years). This change in demographics also is being seen in trauma centers. Emergency department thoracotomy is utilized in an attempt to restore circulation for patients arriving in extremis. The purpose of this study was to investigate the relationship between clinical variables, particularly age, and outcomes for injured patients receiving an emergency department thoracotomy. METHODS: Using the National Trauma Data Bank for years 2008-2012, observations with International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes for exploratory thoracotomy were identified...
February 2, 2018: Surgery
https://www.readbyqxmd.com/read/29393808/imaging-and-surgical-approach-to-a-pediatric-penetrating-intradural-wooden-splinter-case-report
#12
Gabrielle Santangelo, Jonathan Stone, Tyler Schmidt, G Edward Vates, Howard Silberstein, Pierre Girgis
Penetrating spinal injuries by wood are infrequently reported. They are particularly rare in children. Only 6 cases of wooden fragments causing penetrating intradural spinal injury have been reported. The authors report a case of a 3-year-old girl who suffered a penetrating wound on her lower back after sliding on a wood floor. A portion of the extraspinal part of the wooden splinter was removed prior to presentation; however, a high suspicion for retained foreign body was maintained. Findings on CT were equivocal, but the diagnosis was confirmed on MRI...
February 2, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29392073/transverse-cervicothoracic-stabbing-multidisciplinary-management-of-a-surgical-emergency
#13
Elena Molina Fernández, Ramón Moreno-Luna, Francisco López Navas, Marta López Porras, C Giménez, Serafín Sánchez Gómez
Tracheobronchial injuries are closely related to orotracheal intubations and chest traumas. Stabbing injuries are very rare and often life threatening because of the damage to vital structures such as the respiratory tract and large arterial or venous vessels. Early diagnosis and treatment of penetrating neck injuries increase survival rates. We report a case of the tracheobronchial section with a penetrating stabbing wound on the left laterocervical area associated with contralateral pneumothorax, requiring urgent surgical pulmonary repair, tracheal suture, and tracheotomy...
September 2017: Turkish Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29381243/neural-crest-derived-cells-migrate-from-nerve-to-participate-in-achilles-tendon-remodeling
#14
Kang Xu, Xin Pan, Xuefeng Qiu, Dong Wang, Nianguo Dong, Li Yang, Song Li
During tendon injuries, nerve ingrowth is one of the earliest events of tendon repair and remodeling. Since peripheral neurons and associated cells are mostly derived from neural crest (NC) cells, we sought to investigate the role of NC-derived cells in tendon regeneration. Thus, we used Sox10-Cre/ROSA26-Flox-Red Fluorescent Protein (RFP) transgenic mice to trace these cells during tendon regeneration. After 4 weeks of Achilles tendon rupture, the injured tendon tissues were harvested for immunohistological analyses, cell isolation, and phenotype identification...
January 30, 2018: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29379402/colon-trauma-evidence-based-practices
#15
REVIEW
Ryo Yamamoto, Alicia J Logue, Mark T Muir
Colon injury is not uncommon and occurs in about a half of patients with penetrating hollow viscus injuries. Despite major advances in the operative management of penetrating colon wounds, there remains discussion regarding the appropriate treatment of destructive colon injuries, with a significant amount of scientific evidence supporting segmental resection with primary anastomosis in most patients without comorbidities or large transfusion requirement. Although literature is sparse concerning the management of blunt colon injuries, some studies have shown operative decision based on an algorithm originally defined for penetrating wounds should be considered in blunt colon injuries...
January 2018: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/29375943/penetrating-obturator-artery-injury-after-gunshot-wounds-a-successful-multidisciplinary-trauma-team-approach-to-a-potentially-lethal-injury
#16
Tareq I Maraqa, Ji-Sun J Shin, Ismael Diallo, Gul R Sachwani-Daswani, Leo C Mercer
Obturator artery injury (OAI) from pelvic gunshot wounds (GSW) is a rarely reported condition. Hemorrhages from pelvic trauma (PT) are mostly venous. Arterial hemorrhages represent about 10-20% of PTs. When arterial hemorrhages from PT occur, they are a severe and deadly complication often causing significant hemodynamic instability and eventual shock. A 23-year-old male presented to our emergency service via a private vehicle with multiple gunshot wounds to both thighs and to the lower back, resulted in rectal and obturator artery (OA) injuries...
November 17, 2017: Curēus
https://www.readbyqxmd.com/read/29374465/penetrating-aortic-injury-left-untreated-for-20%C3%A2-days-a-case-report
#17
Alessia Giaquinta, Dovile Mociskyte, Giuseppe D'Arrigo, Giuseppe Barbagallo, Francesco Certo, Massimiliano Veroux, Pierfrancesco Veroux
BACKGROUND: Penetrating aortic trauma remains one of the most challenging injuries with a high mortality rate if left untreated, or if the surgical treatment is delayed. We present an uncommon case of a late diagnosed abdominal firearm injury, in which the bullet partially penetrated the wall of the aorta, creating a plug that prevented immediate death due to massive bleeding. CASE PRESENTATION: A 26-year-old Libyan man was a victim of a firearm wound, with a bullet penetrating his abdominal wall from the left to right side...
January 27, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29369940/a-case-study-of-the-ncrp-156-wound-model-of-embedded-du-using-data-from-urine-uranium-concentrations-of-wounded-veterans
#18
Michael T Walkingstick, Eric S Krage, Richard R Brey
Depleted uranium (DU) munitions were initially used by the United States (U.S.) military during the first Persian Gulf War in 1991 in order to penetrate heavily armored vehicles. However, as a result of friendly fire, several U.S. military personnel received intakes from DU munitions. One of the ongoing concerns for these wounded veterans is the potential long-term exposure received from DU embedded fragments. The United States Army Institute of Public Health (AIPH) is the first laboratory that analyzes the urine bioassays from Army Soldiers that are injured with DU fragments...
March 2018: Health Physics
https://www.readbyqxmd.com/read/29368085/selective-nonoperative-management-of-liver-gunshot-injuries
#19
Pradeep Navsaria, Andrew Nicol, Jake Krige, Sorin Edu, Sharfuddin Chowdhury
PURPOSE: Nonoperative management (NOM) of gunshot liver injuries (GLI) is infrequently practiced. The aim of this study was to assess the safety of selective NOM of GLI. METHODS: A prospective, protocol-driven study, which included patients with GLI admitted to a level 1 trauma center, was conducted over a 52-month period. Stable patients without peritonism or sustained hypotension with right-sided thoracoabdominal (RTA) and right upper quadrant (RUQ), penetrating wounds with or without localized RUQ tenderness, underwent contrasted abdominal CT scan to determine the trajectory and organ injury...
January 24, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29356844/characteristics-and-management-of-penetrating-abdominal-injuries-in-a-german-level-i-trauma-center
#20
Patrizia Malkomes, Philipp Störmann, Hanan El Youzouri, Sebastian Wutzler, Ingo Marzi, Thomas Vogl, Wolf Otto Bechstein, Nils Habbe
PURPOSE: Penetrating abdominal injuries caused by stabbing or firearms are rare in Germany, thus there is lack of descriptive studies. The management of hemodynamically stable patients is still under dispute. The aim of this study is to review and improve our management of penetrating abdominal injuries. METHODS: We retrospectively reviewed a 10-year period from the Trauma Registry of our level I trauma center. The data of all patients regarding demographics, clinical and outcome parameters were examined...
January 22, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
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