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https://www.readbyqxmd.com/read/28618650/anti-amnesic-effects-of-ganoderma-species-a-possible-cholinergic-and-antioxidant-mechanism
#1
Ravneet Kaur, Varinder Singh, Richa Shri
Mushrooms are valued for their nutritional as well as medicinal properties. Ganoderma species are used traditionally to treat neurological disorders but scientific evidence for this is insufficient. The present study was designed to systematically evaluate the anti-amnesic effect of selected Ganoderma species i.e. G. mediosinense and G. ramosissimum. Extracts of selected mushroom species were evaluated for their antioxidant activity and acetylcholinesterase (AChE) inhibition using in-vitro assays (DPPH and Ellman tests respectively)...
June 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28618378/simultaneously-upgrading-biogas-and-purifying-biogas-slurry-using-cocultivation-of-chlorella-vulgaris-and-three-different-fungi-under-various-mixed-light-wavelength-and-photoperiods
#2
Weixing Cao, Xue Wang, Shiqing Sun, Changwei Hu, Yongjun Zhao
In order to purify biogas slurry and biogas simultaneously, three different fungi, Pleurotus geesteranus (P. geesteranus), Ganoderma lucidum (G. lucidum), and Pleurotus ostreatus (P. ostreatus) were pelletized with Chlorella vulgaris (C. vulgaris). The results showed that the optimal light wavelength ratio for red:blue was 5:5 for these three different fungi-assisted C. vulgaris, resulting in higher specific growth rate as well as nutrient and CO2 removal efficiency compared with other ratios. G. lucidum/C...
June 1, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28608696/immunomodulatory-activity-of-ganoderma-atrum-polysaccharide-on-purified-t-lymphocytes-through-ca2-can-and-mapk-pathway-based-on-rna-seq
#3
Quan-Dan Xiang, Qiang Yu, Hui Wang, Ming-Ming Zhao, Shi-Yu Liu, Shaoping Nie, Ming-Yong Xie
Our previous study has demonstrated that Ganoderma atrum polysaccharide (PSG-1) has immunomodulatory activity on spleen lymphocytes. However, how PSG-1 exerts its effect on purified lymphocytes is still obscure. Thus, this study aimed to investigate the immunomodulatory activity of PSG-1 on purified T lymphocytes, and further elucidate the underlying mechanism based on RNA-seq. Our results showed that PSG-1 promoted T lymphocytes proliferation and increased the production of IL-2, IFN-γ and IL-12. Meanwhile, RNA-seq analysis found 394 differentially expressed genes...
June 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28606348/about-ganoderma-boninense-in-oil-palm-plantations-of-sumatra-and-peninsular-malaysia-ancient-population-expansion-extensive-gene-flow-and-large-scale-dispersion-ability
#4
Maxime Mercière, Romain Boulord, Catherine Carasco-Lacombe, Christophe Klopp, Yang-Ping Lee, Joon-Sheong Tan, Sharifah S R Syed Alwee, Alba Zaremski, Hubert De Franqueville, Frédéric Breton, Létizia Camus-Kulandaivelu
Wood rot fungi form one of the main classes of phytopathogenic fungus. The group includes many species, but has remained poorly studied. Many species belonging to the Ganoderma genus are well known for causing decay in a wide range of tree species around the world. Ganoderma boninense, causal agent of oil palm basal stem rot, is responsible for considerable yield losses in Southeast Asian oil palm plantations. In a large-scale sampling operation, 357 sporophores were collected from oil palm plantations spread over peninsular Malaysia and Sumatra and genotyped using 11 SSR markers...
June 2017: Fungal Biology
https://www.readbyqxmd.com/read/28605335/in-vitro-expression-of-toll-like-receptors-and-proinflammatory-molecules-induced-by-ergosta-7-22-dien-3-one-isolated-from-a-wild-mexican-strain-of-ganoderma-oerstedii-agaricomycetes
#5
Angel Ramos-Ligonio, Aracely López-Monteon, Maria de la Soledad Lagunes-Castro, Jorge Suarez-Medellin, Cesar Espinoza, Guillermo Mendoza, Angel Trigos
Compounds showing pharmacological activity on the immune system are of interest because of their therapeutic potential in the treatment of many diseases. However, data from primary human immune cells and in vivo studies are limited. The aim of this study was to analyze the ability to induce the expression of Toll-like receptors (TLRs) and proinflammatory molecules on cells involved in the immune system using the compound ergosta-7,22-dien-3- one, isolated from a wild Mexican strain of Ganoderma oerstedii. According to our study, ergosta-7,22-dien-3-one did not present any cytotoxic effect on HeLa or J774A...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28603120/enzyme-inhibitory-antifungal-antibacterial-and-hemolytic-potential-of-various-fractions-of-colebrookia-oppositifolia
#6
Tauheeda Riaz, Muhammad Athar Abbasi, Azizur Rehman, Sabahat Zahra Siddiqui, Muhammad Shahid, Hina Fatima, Muhammad Ashraf, Syeda Abida Ejaz, Zahid Ghulam Rasool, Ghulam Hasan Abbasi
The purpose of the present investigation was to assess the enzyme inhibition, antifungal, antibacterial and hemolytic activities of various fractions of Colebrookia oppositifolia Smith. The MeOH extract of plant was dissolved in dist. water and partitioned with n-hexane, CHCl3, EtOAc and n-BuOH sequentially. Enzyme inhibition studies were done against four enzymes i.e. α-glucosidase, butyrylcholinesterase, acetyl cholinesterase and lipoxygenase. Ethyl acetate fraction possessed very good activity against α-glucosidase (IC50 57...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28592650/identification-of-ganoderma-disease-resistance-loci-using-natural-field-infection-of-an-oil-palm-multiparental-population
#7
Sébastien Tisné, Virginie Pomiès, Virginie Riou, Indra Syahputra, Benoît Cochard, Marie Denis
Multi-parental populations are promising tools for identifying quantitative disease resistance loci. Stem rot caused by Ganoderma boninense is a major threat to palm oil production, with yield losses of up to 80% prompting premature replantation of palms. There is evidence of genetic resistance sources, but the genetic architecture of Ganoderma resistance has not yet been investigated. This study aimed to identify Ganoderma resistance loci using an oil palm multi-parental population derived from nine major founders of ongoing breeding programs...
June 7, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28588565/diversity-of-ligninolytic-enzymes-and-their-genes-in-strains-of-the-genus-ganoderma-applicable-for-biodegradation-of-xenobiotic-compounds
#8
Giselle Torres-Farradá, Ana M Manzano León, François Rineau, Lucía L Ledo Alonso, María I Sánchez-López, Sofie Thijs, Jan Colpaert, Miguel Ramos-Leal, Gilda Guerra, Jaco Vangronsveld
White-rot fungi (WRF) and their ligninolytic enzymes (laccases and peroxidases) are considered promising biotechnological tools to remove lignin related Persistent Organic Pollutants from industrial wastewaters and contaminated ecosystems. A high diversity of the genus Ganoderma has been reported in Cuba; in spite of this, the diversity of ligninolytic enzymes and their genes remained unexplored. In this study, 13 native WRF strains were isolated from decayed wood in urban ecosystems in Havana (Cuba). All strains were identified as Ganoderma sp...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28572880/effect-of-medicinal-mushrooms-on-blood-cells-under-conditions-of-diabetes-mellitus
#9
REVIEW
Taras Vitak, Borys Yurkiv, Solomon Wasser, Eviatar Nevo, Natalia Sybirna
Diabetes mellitus (DM) is the third most common non-infectious disease leading to early disability and high mortality. Moreover, the number of patients is growing every year. The main symptom of DM is hyperglycemia. Increased levels of blood glucose activate polyol, hexosamine, and protein kinase metabolic pathways cause the intensification of non-enzymatic glycosylation and nitration of macromolecules. This, in turn, leads to the development of oxidative and nitrative stresses and secondary complications, such as different kinds of micro- and macroangiopathies...
May 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28543056/cloning-and-analysis-of-the-glwc-1-and-glwc-2-genes-encoding-putative-blue-light-photoreceptor-from-ganoderma-lucidum
#10
Xinran Xu, Xiangdong Chen, Wumengxiao Yu, Yu Liu, Weiwei Zhang, Jin Lan
Blue light plays an important role during the growth of Ganoderma lucidum, one of the best-known medicinal macrofungi in China. In the present study, we cloned Glwc-1 and Glwc-2, the homologue of the blue light photoreceptors Ncwc-1 and Ncwc-2 of Neurospora crassa, from G. lucidum. The deduced amino acid sequence of Glwc-1 contained the similar function domains as NcWC-1 including LOV, PAS B, PAS C, and PAC domains. The deduced amino acid sequence of Glwc-2 contained PAS domain and GATA-type zinc finger (Znf) domain as well as NcWC-2...
May 23, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28536459/a-novel-polycyclic-meroterpenoid-with-aldose-reductase-inhibitory-activity-from-medicinal-mushroom-ganoderma-leucocontextum
#11
Jinjin Zhang, Ke Ma, Hongyu Chen, Kai Wang, Weiping Xiong, Li Bao, Hongwei Liu
No abstract text is available yet for this article.
May 24, 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/28530827/overexpression-of-the-squalene-epoxidase-gene-alone-and-in-combination-with-the-3-hydroxy-3-methylglutaryl-coenzyme-a-gene-increases-ganoderic-acid-production-in-ganoderma-lingzhi
#12
De-Huai Zhang, Lu-Xi Jiang, Na Li, Xuya Yu, Peng Zhao, Tao Li, Jun-Wei Xu
The squalene epoxidase (SE) gene from the biosynthetic pathway of ganoderic acid (GA) was cloned and overexpressed in Ganoderma lingzhi. The strain that overexpressed the SE produced approximately 2 times more GA molecules than the wild-type (WT) strain. Moreover, SE overexpression upregulated lanosterol synthase gene expression in the biosynthetic pathway. These results indicated that SE stimulates GA accumulation. Then, the SE and 3-hydroxy-3-methylglutaryl coenzyme A (HMGR) genes were simultaneously overexpressed in G...
May 30, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28527898/triterpenes-and-meroterpenes-from-ganoderma-lucidum-with-inhibitory-activity-against-hmgs-reductase-aldose-reductase-and-%C3%AE-glucosidase
#13
Baosong Chen, Jin Tian, Jinjin Zhang, Kai Wang, Li Liu, Bo Yang, Li Bao, Hongwei Liu
Seven new compounds including four lanostane triterpenoids, lucidenic acids Q-S (1-3) and methyl ganoderate P (4), and three triterpene-farnesyl hydroquinone conjugates, ganolucinins A-C (5-7), one new natural product ganomycin J (8), and 73 known compounds (9-81) were isolated from fruiting bodies of Ganoderma lucidum. The structures of the compounds 1-8 were determined by spectroscopic methods. Bioactivities of compounds isolated were assayed against HMG-CoA reductase, aldose reductase, α-glucosidase, and PTP1B...
May 17, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28510717/fast-population-growth-in-physogastry-reproduction-of-luciaphorus-perniciosus-acari-pygmephoridae-at-different-temperatures
#14
Prapassorn Bussaman, Chirayu Sa-Uth, Angsumarn Chandrapatya, Remzi Atlihan, Ayhan Gökçe, Pavel Saska, Hsin Chi
Luciaphorus perniciosus Rack is one of the most serious pests of several cultivated mushroom species including Ganoderma lucidum (Fr.), Flammulina velutipes Karst., Auricularia polytricha (Mont.) Saac., Lentinus polychrous Lev., and Lentinus squarrosulus (Mont.) Singer in Thailand. Adult female Lu. perniciosus produce offspring inside their physogastric hysterosomas, with all embryos developing through to the adult stage while remaining in the abdomen. Once the abdomen ruptures, the female parent dies and the offspring consisting of mostly fertilized female adults along with a few male adults continue to emerge from the cadaver of the mother for a period of several days...
May 16, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28508676/two-new-compounds-from-the-fruiting-bodies-of-ganoderma-philippii
#15
Shuang Yang, Qing-Yun Ma, Fan-Dong Kong, Qing-Yi Xie, Sheng-Zhuo Huang, Li-Man Zhou, Hao-Fu Dai, Zhi-Fang Yu, You-Xing Zhao
Two new compounds, philippin (1) and 3β,9α,14α-trihydroxy-(22E,24R)-ergost-22-en-7-one (2), were isolated from the fruiting bodies of Ganoderma philippii. Their structures were elucidated on the basis of the spectroscopic technologies, including 1D and 2D NMR as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) showed compound 1 exhibited weak inhibitory activity against AChE.
May 16, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28504879/antitubercular-activity-of-mycelium-associated-ganoderma-lanostanoids
#16
Masahiko Isaka, Panida Chinthanom, Malipan Sappan, Sumalee Supothina, Vanicha Vichai, Kannawat Danwisetkanjana, Thitiya Boonpratuang, Kevin D Hyde, Rattaket Choeyklin
In a continuation of our research into antitubercular lanostane triterpenoids from submerged cultures of Ganoderma species, three strains, Ganoderma orbiforme BCC 22325, Ganoderma sp. BCC 60695, and Ganoderma australe BCC 22314, have been investigated. Fourteen new lanostane triterpenoids, together with 35 known compounds, were isolated. Antitubercular activities of these mycelium-associated Ganoderma lanostanoids against Mycobacterium tuberculosis H37Ra were evaluated. Taken together with the assay data of previously isolated compounds, structure-activity relationships of the antitubercular activity are proposed...
May 15, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28496309/effect-of-electromagnetic-fields-and-antioxidants-on-the-trace-element-content-of-rat-teeth
#17
Mehmet Sinan Dogan, Mehmet Cihan Yavas, Yasemin Yavuz, Sait Erdogan, İsmail Yener, İbrahim Simsek, Zeki Akkus, Veysel Eratilla, Abdulsamet Tanik, Mehmet Zulkuf Akdag
The purpose of this study was to examine the possible effect of extremely low-frequency electromagnetic fields (ELF-EMFs), from a high-voltage source, on rat teeth in terms of changes in trace elements (TEs) and the effect of antioxidants (melatonin [MLT] and Ganoderma lucidum [GL]) in counteracting these effects. We used adult male Wistar albino rats with a mean weight of 250-300 g and divided the rats into eight groups. The groups were subjected to an ELF-EMF that was applied with a high-voltage line for 8 hours/day for 26 days (Groups I, II, and III) or 52 days (Groups V, VI, and VII)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28491940/data-on-eleven-sesquiterpenoids-from-the-cultured-mycelia-of-ganoderma-capense
#18
Zhen Tan, Jinlian Zhao, Jimei Liu, Min Zhang, Ridao Chen, Kebo Xie, Jungui Dai
The data included in this paper are associated with the research article entitled "Sesquiterpenoids from the cultured mycelia of Ganoderma capense" [1]. (1)H NMR, (13)C NMR, DEPT, HSQC, (1)H-(1)H COSY, HMBC, NOESY, HRESIMS, and IR spectra of Ganodermanol A-H (1-11), together with Mo2(AcO)4-induced CD spectrum of Ganodermanol A, CD spectra of Ganodermanol D-E were included in the Data in Brief article. In addition, the cytotoxicities and anti-HIV-1 activity of isolated compounds were also included in the Data in Brief article...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28484937/effects-of-ganoderma-lucidum-shell-broken-spore-on-oxidative-stress-of-the-rabbit-urinary-bladder-using-an-in-vivo-model-of-ischemia-reperfusion
#19
Robert M Levin, Li Xia, Wu Wei, Catherine Schuler, Robert E Leggett, Alpha D-Y Lin
Oxidative stress plays an important role in specific disease pathophysiology and the aging process. In the history of human kind, many herbs were utilized for disease prevention and anti-aging treatment. However, there are few direct evidences provided by modern laboratory technology. The current study was designed to evaluate Ganoderma Lucidum's (GL) ability to reduce the damage from in vivo ischemia/reperfusion (I/R) using a rabbit model of I/R that has been effectively utilized to prove the effects of drugs and supplements to reduce oxidative stress...
May 8, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28473815/gel-based-purification-and-biochemical-study-of-laccase-isozymes-from-ganoderma-sp-and-its-role-in-enhanced-cotton-callogenesis
#20
Amit Kumar, Deepti Singh, Krishna K Sharma, Sakshi Arora, Amarjeet K Singh, Sarvajeet S Gill, Barkha Singhal
Basidiomycetous fungi, Ganoderma lucidum MDU-7 and Ganoderma sp. kk-02 secreted multiple laccase isozymes under diverse growth condition. Aromatic compounds and metal salts were also found to regulate the differential expression of laccase isozymes from both the Ganoderma sp. Laccase isozymes induced in the presence of copper from G. lucidum MDU-7 were purified by gel-based (native-PAGE) purification method. The purity of laccase isozymes was checked by zymogram and SDS-PAGE. The SDS-PAGE of purified proteins confirmed the multimeric nature of laccase isozymes...
2017: Frontiers in Microbiology
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