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Transactional analysis

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https://www.readbyqxmd.com/read/28968797/ipromoter-2l-a-two-layer-predictor-for-identifying-promoters-and-their-types-by-multi-window-based-pseknc
#1
Bin Liu, Fan Yang, De-Shuang Huang, Kuo-Chen Chou
Motivation: Being responsible for initiating transaction of a particular gene in genome, promoter is a short region of DNA. Promoters have various types with different functions. Owing to their importance in biological process, it is highly desired to develop computational tools for timely identifying promoters and their types. Such a challenge has become particularly critical and urgent in facing the avalanche of DNA sequences discovered in the postgenomic age. Although some prediction methods were developed, they can only be used to discriminate a specific type of promoters from non-promoters...
September 14, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28940074/imaging-of-dna-and-protein-by-sfm-and-combined-sfm-tirf-microscopy
#2
Małgorzata Grosbart, Dejan Ristić, Humberto Sánchez, Claire Wyman
Direct imaging is invaluable for understanding the mechanism of complex genome transactions where proteins work together to organize, transcribe, replicate and repair DNA. Scanning (or atomic) force microscopy is an ideal tool for this, providing 3D information on molecular structure at nm resolution from defined components. This is a convenient and practical addition to in vitro studies as readily obtainable amounts of purified proteins and DNA are required. The images reveal structural details on the size and location of DNA bound proteins as well as protein-induced arrangement of the DNA, which are directly correlated in the same complexes...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28938612/magnetic-resonance-imaging-tracking-and-assessing-repair-function-of-the-bone-marrow-mesenchymal-stem-cells-transplantation-in-a-rat-model-of-spinal-cord-injury
#3
Hongwu Zhang, Liqin Wang, Shihong Wen, Qingfeng Xiang, Xianhong Xiang, Caixia Xu, Yong Wan, Jingnan Wang, Bin Li, Yiqian Wan, Zhiyun Yang, David Y B Deng
The transplantation of bone marrow mesenchymal stem cells (BMSCs) to repair spinal cord injury (SCI) has become a promising therapy. However, there is still a lack of visual evidence directly implicating the transplanted cells as the source of the improvement of spinal cord function. In this study, BMSCs were labeled with NF-200 promoter and lipase-activated gadolinium-containing nanoparticles (Gd-DTPA-FA). Double labeled BMSCs were implanted into spinal cord transaction injury in rat models in situ, the function recovery was evaluated on 1st, 7th, 14th, 28 th days by MRI, Diffusion Tensor Imaing, CT imaging and post-processing, and histological observations...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28934923/discriminative-sparse-features-for-alzheimer-s-disease-diagnosis-using-multimodal-image-data
#4
A Ortiz, F Lozano, J M Gorriz, J Ramírez, F J Martinez-Murci, For The Alzheimer S Disease Neuroimaging Initiative
BACKGROUND: Feature extraction in medical image processing still remains a challenge, especially in high-dimensionality datasets, where the expected number of available samples is considerably lower than the dimension of the feature space. This is a common problem in real-world data, and, specifically, in medical image pro- cessing as, while images are composed of hundreds of thousands voxels, only a reduced number of patients are available. OBJECTIVE: Extracting descriptive and discriminative features to represent each sample (image) by a small number of features, which is particularly important in classification task, due to the curse of dimensionality problem...
September 21, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28926025/animal-health-and-price-transmission-along-livestock-supply-chains
#5
M Aragrande, M Canali
Animal health diseases can severely affect the food supply chain by causing variations in prices and market demand. Price transmission analysis reveals in what ways price variations are transmitted along the supply chain, and how supply chains of substitute products and different regional markets are also affected. In perfect markets, a price variation would be completely and instantaneously transmitted across the different levels of the supply chain: producers, the processing industry, retailers and consumers...
April 2017: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28885861/deuterated-drugs-updates-and-obviousness-analysis
#6
Graham S Timmins
The pharmacokinetics and/or toxicity of many known drugs can be modified by selective deuteration, an area of significant commercial interest and scientific and regulatory progress. Areas covered: This review firstly discusses recent developments in deuterated drugs including the FDA approval of deutetrabenazine. Secondly, it discusses 35 U.S.C. §103 'obviousness' as it relates to recent patent prosecution, and also to Inter Partes Review (IPR). IPR is a new post-award review of patentability under §102 or §103, two IPR petitions upon deuterated drugs have been instituted and included §103 arguments...
September 14, 2017: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/28880372/the-making-of-a-moral-economy-women-s-views-of-monetary-transactions-in-an-egg-sharing-for-research-scheme
#7
Erica Haimes, Robin Williams
There are growing debates about the appropriateness of offering money in exchange for the provision of bodily materials for clinical treatment and research. The bioethics literature and many practice guidelines have generally been opposed to such entanglement, depicting the use of money as contaminating, creating undue inducement, exploitation and commodification of the human body. However, two elements have been missing from these debates: (i) the perspectives of those people providing bodily materials when money is offered; and (ii) systematic empirical engagement with the notion of 'money' itself...
September 7, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28880181/eva-visual-analytics-to-identify-fraudulent-events
#8
Roger A Leite, Theresia Gschwandtner, Silvia Miksch, Simone Kriglstein, Margit Pohl, Erich Gstrein, Johannes Kuntner
Financial institutions are interested in ensuring security and quality for their customers. Banks, for instance, need to identify and stop harmful transactions in a timely manner. In order to detect fraudulent operations, data mining techniques and customer profile analysis are commonly used. However, these approaches are not supported by Visual Analytics techniques yet. Visual Analytics techniques have potential to considerably enhance the knowledge discovery process and increase the detection and prediction accuracy of financial fraud detection systems...
August 31, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28871456/queueing-theoretic-analysis-of-labor-and-delivery-understanding-management-styles-and-c-section-rates
#9
Matthew Gombolay, Toni Golen, Neel Shah, Julie Shah
Childbirth is a complex clinical service requiring the coordinated support of highly trained healthcare professionals as well as management of a finite set of critical resources (such as staff and beds) to provide safe care. The mode of delivery (vaginal delivery or cesarean section) has a significant effect on labor and delivery resource needs. Further, resource management decisions may impact the amount of time a physician or nurse is able to spend with any given patient. In this work, we employ queueing theory to model one year of transactional patient information at a tertiary care center in Boston, Massachusetts...
September 4, 2017: Health Care Management Science
https://www.readbyqxmd.com/read/28861551/access-to-medical-and-mental-health-services-across-the-hiv-care-continuum-among-young-transgender-women-a-qualitative-study
#10
Nadia Dowshen, Susan Lee, Joshua Franklin, Marné Castillo, Frances Barg
Purpose: (1) To describe psychosocial, medical, and mental health outcomes of young transgender women (YTW) living with or at risk for HIV infection and (2) to explore barriers and facilitators to medical and mental health services across the HIV care continuum. Methods: We conducted a cross-sectional observational study of YTW aged 16-24 years who were at risk for contracting or living with HIV. Participants were recruited from an adolescent HIV clinic and local community-based organizations that serve YTW...
2017: Transgender Health
https://www.readbyqxmd.com/read/28857687/-there-was-a-struggle-between-my-instinct-and-my-head-women-s-perception-and-experience-of-masturbation-in-contemporary-vietnam
#11
Bui Thu Huong, Pranee Liamputtong
This paper investigates how masturbation, as one form of non-coital sexual practice, is interpreted and experienced by young married women in contemporary Vietnam. Data were collected through semi-structured interviews with 20 professional women aged 25-40 living in Hanoi. Thematic analysis suggests that by embracing the pursuit of pleasure and aspiring to achieve this goal, many women stake a claim for modernity by promoting the idea that they are no longer traditional in this particular domain of social life...
August 31, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28845320/transactional-sex-between-men-and-its-implications-on-hiv-and-sexually-transmitted-infections-in-nigeria
#12
Eniola A Bamgboye, Titilope Badru, Afolabi Bamgboye
INTRODUCTION: Men who have transactional sex with men (MTSM) are known to be at higher risk for HIV and sexually transmitted infections (STIs). This study explored the risk factors associated with STI symptoms and HIV prevalence among men who have transactional sex with men in Nigeria. METHODS: In 2014, a cross-sectional study, using respondent driven sampling technique, was carried out to recruit 3,172 MSM across eight states in Nigeria. Relevant information on sociodemographic characteristics, sexual behaviors, and self-reported symptoms of STI was obtained...
2017: Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28844622/from-transitions-to-transformation-a-study-of-pharmacists-developing-patient-centered-communication-skills
#13
Karen Luetsch, Judith Burrows
BACKGROUND: Pharmacists' communication with patients often focuses on technical aspects of advice giving, while limiting socio-emotional content. To develop pharmacists' patient-centered communication a learning and practice module integrating motivational interviewing (MI) was designed for an online postgraduate program, and its impact on their self-described practice evaluated. OBJECTIVES: To investigate whether training in patient-centered communication changes pharmacists' perceptions of communicating with patients, and how any changes in their communication style influenced interactions and relationships with patients...
August 12, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28836298/a-qualitative-examination-of-patients-experiences-of-dietitians-consultation-engagement-styles-within-nephrology
#14
A Morris, T Herrmann, C Liles, C Roskell
BACKGROUND: Dietitians provide individuals with tailored, practical nutritional advice. For this reason, skills in effective interpersonal communication are essential. In the case of chronic kidney disease, the specifics of dietary advice may change according to renal function. The conveyance of accurate dietary advice and compliance is critical and requires full engagement with the service. The effect of communication styles on patients ' engagement experiences with renal dietetics is unknown...
August 23, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28830394/young-women-s-perceptions-of-transactional-sex-and-sexual-agency-a-qualitative-study-in-the-context-of-rural-south-africa
#15
Meghna Ranganathan, Catherine MacPhail, Audrey Pettifor, Kathleen Kahn, Nomhle Khoza, Rhian Twine, Charlotte Watts, Lori Heise
BACKGROUND: Evidence shows that HIV prevalence among young women in sub-Saharan Africa increases almost five-fold between ages 15 and 24, with almost a quarter of young women infected by their early-to mid-20s. Transactional sex or material exchange for sex is a relationship dynamic that has been shown to have an association with HIV infection. METHODS: Using five focus group discussions and 19 in-depth interviews with young women enrolled in the HPTN 068 conditional cash transfer trial (2011-2015), this qualitative study explores young women's perceptions of transactional sex within the structural and cultural context of rural South Africa...
August 22, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28775998/industry-payments-to-urologists-in-2014-an-analysis-of-the-open-payments-program
#16
Parth K Modi, Nicholas J Farber, Michael E Zavaski, Thomas L Jang, Eric A Singer, Steven L Chang
INTRODUCTION: Physician-industry relationships are common in the U.S. and a source of considerable public scrutiny. The Open Payments program is a public database of all physician-industry financial interactions in the U.S. administered by the Centers for Medicare & Medicaid Services. In this study we describe payments received by urologists for research and nonresearch purposes. METHODS: The number and value of payments to urologists were determined using Open Payments program data...
July 2017: Urology Practice
https://www.readbyqxmd.com/read/28764585/sexual-transactions-between-long-distance-truck-drivers-and-female-sex-workers-in-south-africa
#17
Nosipho Faith Makhakhe, Tim Lane, James McIntyre, Helen Struthers
BACKGROUND: Female sex workers (FSWs) and long distance truck drivers (LDTDs) are considered key populations at high risk for HIV transmission due to high prevalence. The intersection of these mobile populations presents unique challenges in the fight against HIV and the movement towards reducing new infections. OBJECTIVE: The purpose of this study was to explore the nature of sex trade along a particular transport route. Sexual transactions and the vulnerabilities that exist between these two groups with regards to HIV/AIDS are described, with the purpose of furthering the agenda for targeted interventions...
2017: Global Health Action
https://www.readbyqxmd.com/read/28742457/epidemic-network-analysis-for-mitigation-of-invasive-pathogens-in-seed-systems-potato-in-ecuador
#18
Christopher Buddenhagen, John Hernandez Nopsa, Kelsey F Andersen, Jorge Andrade-Piedra, Greg Forbes, Peter Kromann, Sara Thomas-Sharma, Pilar Useche, Karen A Garrett
Seed systems have an important role in the distribution of high quality seed and improved varieties. The structure of seed networks also helps to determine the epidemiological risk for seedborne disease. We present a new method for evaluating the epidemiological role of nodes in seed networks, and apply it to a regional potato farmer consortium (CONPAPA) in Ecuador. We surveyed farmers to estimate the structure of networks of farmer seed tuber and ware potato transactions, and farmer information sources about pest and disease management...
July 25, 2017: Phytopathology
https://www.readbyqxmd.com/read/28737057/commercial-transactions-in-children-the-case-of-ghana
#19
Mensah Adinkrah
The current article represents an examination of commercial transactions involving the sale of children in contemporary Ghana. It presents the results of a criminological analysis of 20 cases of commercial transactions in children in Ghana. It describes the sociodemographic characteristics of offenders and victims, victim-offender relationships, offender motivations, public reactions to the phenomenon, as well as the criminal justice system's responses to the crime. The data were extracted from Ghanaian print and electronic presses...
July 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/28709384/beyond-words-using-qualitative-video-methods-for-researching-occupation-with-young-children
#20
Helen Lynch, Mandy Stanley
Researching with children is fundamental for furthering our understanding of children's occupational worlds. Furthermore, researching occupation from a transactional perspective is important for gaining a deeper understanding. However historically, most approaches to researching with children do not capture the transactional nature of occupation. The use of video methods in qualitative research is proposed as a potential solution. This article illustrates how videography can be used as an effective, inclusive qualitative research method, and uses a study of infant play occupation to illuminate video techniques...
July 1, 2017: OTJR: Occupation, Participation and Health
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