keyword
MENU ▼
Read by QxMD icon Read
search

osteoarthritis and obesity

keyword
https://www.readbyqxmd.com/read/29444323/the-role-of-fat-and-inflammation-in-the-pathogenesis-and-management-of-osteoarthritis
#1
Hema Urban, Christopher B Little
OA is a complex disease involving mechanical, metabolic and inflammatory contributions to its aetiology. A key risk factor, obesity, is becoming an increasing focus of research due to its multiple potential impacts on OA incidence, progression and symptom severity. An increased load due to an increase in body mass has been well established as a mechanical contribution to the pathophysiology of OA. However, evidence of obesity-linked to OA in non-weight-bearing joints has implicated the biological role of adipose inflammation and metabolic abnormalities in OA...
February 9, 2018: Rheumatology
https://www.readbyqxmd.com/read/29428452/association-between-dietary-glycemic-index-and-knee-osteoarthritis-the-korean-national-health-and-nutrition-examination-survey-2010-2012
#2
Min Wook So, Sunggun Lee, Seong-Ho Kim
BACKGROUND: Obesity and metabolic abnormalities are important risk factors for knee osteoarthritis (KOA). Recent epidemiologic studies have found that a high glycemic index (GI) and glycemic load (GL) diet are associated with a higher risk for metabolic complications and cardiovascular mortality. OBJECTIVE: We aimed to examine the association between dietary GI, dietary GL, and KOA among Korean adults. DESIGN: This was a cross-sectional study that analyzed data obtained from the Korean National Health and Nutrition Examination Survey 2010-2012...
February 7, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29413795/effects-of-sex-and-obesity-on-gait-biomechanics-before-and-six-months-after-total-knee-arthroplasty-a-longitudinal-cohort-study
#3
K L Paterson, L Sosdian, R S Hinman, T V Wrigley, J Kasza, M Dowsey, P Choong, K L Bennell
BACKGROUND: Gait biomechanics, sex, and obesity can contribute to suboptimal outcomes from primary total knee arthroplasty. The aims of this study were to i) determine if sex and/or obesity influence the amount of change in gait biomechanics from pre-surgery to six months post-surgery and; ii) assess if gait returns to normal in men and women. METHODS: Three-dimensional gait analysis was performed on 43 patients undergoing primary total knee arthroplasty for knee osteoarthritis (pre- and six months post-operative) and 40 asymptomatic controls...
January 29, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29413192/editorial-commentary-can-we-achieve-personalized-risk-assessment-in-hip-arthroscopy
#4
EDITORIAL
Thomas Parker Vail
Gender, age, obesity, osteoarthritis, absence of labral repair, and index procedure performed by a lower volume surgeon were identified as risk factors for reoperation in a statewide study of hip arthroscopy. Although this analysis is helpful for benchmarking expectations for outcome in hip arthroscopy, unaccounted patient variables in the database could significantly complicate and confound the point of care application of the findings.
February 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29397117/the-association-between-obesity-and-disability-in-survivors-of-joint-surgery-analysis-of-the-health-and-retirement-study
#5
T G Gaulton, L A Fleisher, M D Neuman
BACKGROUND: Obesity is associated with osteoarthritis and the need for joint surgery. Obese patients who undergo joint surgery may have a higher risk of morbidity compared with normal or overweight patients but less is known about their risk of postoperative disability. The primary objective of our study was to determine the association between obesity and the development of new dependence in activities of daily living within 2 years after joint surgery. METHODS: We obtained data from the Health and Retirement Study, a longitudinal survey of older Americans...
January 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29393196/responsiveness-of-infrapatellar-fat-pad-volume-change-to-body-weight-loss-or-gain-data-from-the-osteoarthritis-initiative
#6
Eva Steidle-Kloc, Torben Dannhauer, Wolfgang Wirth, Felix Eckstein
Obesity is a potent risk factor for knee osteoarthritis (OA) that is driven by mechanical and potentially endocrine mechanisms, and it affects women more frequently than men. The infrapatellar fat pat (IPFP) represents a potential link between obesity, intra-articular inflammation and structural pathology. Here we investigate whether the IPFP is responsive to body weight loss/gain in women and how its responsiveness to weight change compares to that of subcutaneous fat (SCF) of the thigh. All female participants of the Osteoarthritis Initiative (OAI) with ≥10% weight loss/gain between baseline and a 2-year follow-up were included...
February 1, 2018: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/29391831/metabolic-syndrome-as-a-risk-factor-for-total-hip-or-knee-replacement-due-to-primary-osteoarthritis-a-prospective-cohort-study-the-hunt-study-and-the-norwegian-arthroplasty-register
#7
Alf Inge Hellevik, Marianne Bakke Johnsen, Arnulf Langhammer, Valborg Baste, Ove Furnes, Kjersti Storheim, John Anker Zwart, Gunnar Birkeland Flugsrud, Lars Nordsletten
Objective: Biochemical changes associated with obesity may accelerate osteoarthritis beyond the effect of mechanical factors. This study investigated whether metabolic syndrome and its components (visceral obesity, hypertension, dyslipidemia and insulin resistance) were risk factors for subsequent total hip replacement (THR) or total knee replacement (TKR) due to primary osteoarthritis. Design: In this prospective cohort study, data from the second survey of the Nord-Trøndelag Health Study 2 (HUNT2) were linked to the Norwegian Arthroplasty Register for identification of the outcome of THR or TKR...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29386643/mitochondrial-genetic-haplogroups-and-incident-obesity-a-longitudinal-cohort-study
#8
Nicola Veronese, Brendon Stubbs, Ai Koyanagi, Alberto Vaona, Jacopo Demurtas, Patricia Schofield, Trevor Thompson, Stefania Maggi
BACKGROUND/OBJECTIVES: A small number of case-control studies have suggested that mitochondrial haplogroups could be associated with obesity. We examined whether obesity risk was influenced by mitochondrial haplogroup in a large North American cohort across an 8-year period. We conducted a longitudinal cohort study including individuals from the Osteoarthritis Initiative. SUBJECTS/METHODS: Mitochondrial haplogroups were determined by sequencing and PCR-RFLP techniques using this nomenclature: HV, JT, KU, IWX, and super HV/others...
January 31, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29381493/is-the-association-between-obesity-and-hip-osteoarthritis-surgery-explained-by-familial-confounding
#9
Karin Magnusson, Katrina J Scurrah, Ragnhild Elise Ørstavik, Thomas Sevenius Nilsen, Ove Furnes, Kåre Birger Hagen
OBJECTIVE: Familial confounding is confounding due to genetics or environmental exposures shared by family members. We aimed to study whether familial confounding explains the association between body mass index (BMI) and severe hip osteoarthritis (OA). DESIGN: We linked data from the Norwegian Arthroplasty Registry with the Norwegian Twin Registry on the National ID-number in 2014, generating a population-based prospective cohort study of same-sex twins born 1915-60 (53...
January 29, 2018: Epidemiology
https://www.readbyqxmd.com/read/29378442/female-hormonal-factors-and-osteoarthritis-of-the-knee-hip-and-hand-a-narrative-review
#10
S M Hussain, F M Cicuttini, B Alyousef, Y Wang
Osteoarthritis is a leading cause of disability with no cure. The incidence of osteoarthritis is sexually dimorphic: women have a higher rate of osteoarthritis than men after the age of 50. Research has investigated the contribution of sex hormones, reproductive factors and hormone supplementation to osteoarthritis. It has been recognized that different joints are susceptible to different risk factors for osteoarthritis. We reviewed the evidence for the effect of endogenous sex hormones, reproductive factors and hormone supplementation on joint-specific osteoarthritis of the knee, hip and hand...
January 30, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29375253/evaluation-of-functional-characteristics-in-patients-with-knee-osteoarthritis
#11
Serkan Bakirhan, Ozgur Bozan, Bayram Unver, Vasfi Karatosun
Objective: This study evaluated the physical and functional characteristics of Turkish patients with knee osteoarthritis and how this disease affects their physical and functional status. Methods: This study included 320 patients, who were evaluated to assess body mass index (BMI) and Hospital for Special Surgery (HSS) score in terms of age, sex and functional characteristics. Results: Mean patient age was 66.92±8.89 years and mean BMI was 31...
November 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/29373032/tissue-level-diet-and-sex-by-diet-interactions-reveal-unique-metabolite-and-clustering-profiles-using-untargeted-liquid-chromatography-mass-spectrometry-on-adipose-skeletal-muscle-and-liver-tissue-in-c57bl6-j-mice
#12
Ann Wells, William T Barrington, Stephen Dearth, Amanda May, David W Threadgill, Shawn R Campagna, Brynn H Voy
Dietary intervention is commonly used for weight loss or to improve health, as diet-induced obesity increases risk of developing type 2 diabetes, hypertension, cardiovascular disease, stroke, osteoarthritis, and certain cancers. Various dietary patterns are associated with effects on health, yet little is known about the effects of diet at the tissue level. Using untargeted metabolomics, this study aimed to identify changes in water-soluble metabolites in C57BL/6J males and females, fed one of five diets (Japanese, ketogenic, Mediterranean, American, and standard mouse chow) for seven months...
January 26, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29359299/comparing-the-efficacy-of-the-total-stabilizing-and-posterior-stabilizing-knee-prostheses-in-obese-and-preobese-females-a-retrospective-cohort-study
#13
Kellen Worhacz, Marc C Jacofsky, David J Jacofsky, Sarim Ahmed
Obesity is associated with increased surgical complications that may lead to suboptimal total knee arthroplasty (TKA) outcomes. Additionally, females exhibit increased rates of severe, clinical osteoarthritis OA, along with increased ligamentous laxity. Therefore, obese females present a particularly challenging case for TKA with increased joint loads coupled with a propensity for instability. This study retrospectively analyzed knee range of motion and stability of one TKA designs with two different degrees of polyethylene conformity in the obese female population...
January 22, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29353745/comparison-of-soft-tissue-artifact-and-its-effects-on-knee-kinematics-between-non-obese-and-obese-subjects-performing-a-squatting-activity-recorded-using-an-exoskeleton
#14
Julien Clément, Jaques A de Guise, Alexandre Fuentes, Nicola Hagemeister
BACKGROUND: Rigid attachment systems are one of the methods used to compensate for soft tissue artifact (STA) inherent in joint motion analyses. RESEARCH QUESTION: The goal of this study was to quantify STA of an exoskeleton design to reduce STA at the knee, and to assess the accuracy of 3D knee kinematics recorded with the exoskeleton in non-obese and obese subjects during quasi-static weight-bearing squatting activity using biplane radiography. METHODS: Nine non-obese and eight obese subjects were recruited...
January 12, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29331761/prevention-of-articular-cartilage-degeneration-in-a-rat-model-of-monosodium-iodoacetate-induced-osteoarthritis-by-oral-treatment-with-withaferin-a
#15
Dharmendra Choudhary, Sulekha Adhikary, Naseer Ahmad, Priyanka Kothari, Ashwni Verma, Prabodh Kumar Trivedi, Prabhat Ranjan Mishra, Ritu Trivedi
Withaferin A (WFA), a highly oxygenated withanolide is used for anti-osteoporotic, fracture healing, obesity control as medicine and dietary supplement in Ayurveda and Unani medicine but its potential remains to be investigate for the osteoarthritis studies. In the present study, chondro-protective effects of WFA, under in vitro and in vivo conditions were evaluated. In-vitro pharmacological activity of WFA was tested on rat articular chondrocytes through MTT, DPPH, different staining, FACS and translation studies...
January 10, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29330101/telephone-based-weight-loss-support-for-patients-with-knee-osteoarthritis-a-pragmatic-randomized-controlled-trial
#16
Kate M O'Brien, John Wiggers, Amanda Williams, Elizabeth Campbell, Rebecca K Hodder, Luke Wolfenden, Sze Lin Yoong, Emma K Robson, Robin Haskins, Steven J Kamper, Chris Rissel, Christopher M Williams
OBJECTIVE: To determine the effectiveness of telephone-based weight loss support in reducing the intensity of knee pain in patients with knee osteoarthritis, who are overweight or obese, compared to usual care. DESIGN: We conducted a parallel randomized controlled trial (RCT), embedded within a cohort multiple RCT of patients on a waiting list for outpatient orthopaedic consultation at a tertiary referral hospital in NSW, Australia. Patients with knee osteoarthritis, classified as overweight or obese (body mass index between ≥27kg/m2 and <40kg/m2) were randomly allocated to receive referral to an existing non-disease specific government funded 6-month telephone-based weight management and healthy lifestyle service or usual care...
January 9, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29327778/impact-of-physical-activity-and-body-mass-index-in-cardiovascular-and-musculoskeletal-health-a-review
#17
Morad Chughtai, Chukwuweike U Gwam, Nequesha Mohamed, Anton Khlopas, Nipun Sodhi, Assem A Sultan, Anil Bhave, Michael A Mont
Due to an increasing elderly population coupled with a growing obesity epidemic, there has been an increased prevalence in cardiovascular and musculoskeletal diseases. This has led to an increased burden in healthcare expenditures, now estimated to be over 17.8% of gross domestic product. As a result, physical activity has been increasingly encouraged due to its potential prophylactic effects on health. Recent reports have demonstrated a relationship between physical activity and body mass index (BMI) on cardiovascular and musculoskeletal health...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29325839/the-effect-of-low-load-exercise-on-joint-pain-function-and-activities-of-daily-living-in-patients-with-knee-osteoarthritis
#18
Jason Peeler, Jacquie Ripat
BACKGROUND: Knee osteoarthritis has a lifetime risk of nearly one in two, with obese individuals being most susceptible. While exercise is universally recognized as a critical component for management, unsafe or ineffective exercise frequently leads to exacerbation of joint symptoms. AIM: Evaluate the effect of a 12week lower body positive pressure (LBPP) supported low-load treadmill walking program on knee pain, joint function, and performance of daily activities in patients with knee osteoarthritis (OA)...
January 8, 2018: Knee
https://www.readbyqxmd.com/read/29300722/health-care-provider-counseling-for-physical-activity-or-exercise-among-adults-with-arthritis-united-states-2002-and-2014
#19
Jennifer M Hootman, Louise B Murphy, John D Omura, Teresa J Brady, Michael Boring, Kamil E Barbour, Charles G Helmick
Arthritis affects an estimated 54 million U.S. adults and, as a common comorbidity, can contribute arthritis-specific limitations or barriers to physical activity or exercise for persons with diabetes, heart disease, and obesity (1). The American College of Rheumatology's osteoarthritis management guidelines recommend exercise as a first-line, nonpharmacologic strategy to manage arthritis symptoms (2), and a Healthy People 2020 objective is to increase health care provider counseling for physical activity or exercise among adults with arthritis...
January 5, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29285567/management-of-symptomatic-knee-osteoarthritis-in-obesity-a-survey-of-orthopaedic-surgeons-opinions-and-practice
#20
Daniel S Hill, Matthew Freudmann, Jamie C Sergeant, Tim Board
INTRODUCTION: The aim of this survey was to explore knee surgeons' opinions and practices regarding the management of symptomatic knee osteoarthritis in obesity. METHODS: Questionnaires were sent electronically to all consultant members of the British Association for Surgery of the Knee. RESULTS: The response rate was 52%. The survey showed considerable practice variation and divided opinion on the evidence base. The majority stated that weight loss should be the first-line treatment...
December 28, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
keyword
keyword
116006
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"