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https://www.readbyqxmd.com/read/28750427/environmental-risk-factors-for-type-1-diabetes-mellitus-development
#1
Boljat Antonela, Gunjača Ivana, Konstantinović Ivan, Vidan Nikolina, Boraska Perica Vesna, Pehlić Marina, Škrabić Veselin, Zemunik Tatijana
Background Although environmental factors induce development of type 1 diabetes mellitus (T1DM) in genetically susceptible individuals, many of those factors have been uncovered. Therefore, the aim of the present study was to analyze associations of T1DM with a wide range of environmental factors. Material and Methods A case-control study was conducted on 249 diabetic and 255 healthy individuals from the Dalmatian region of South Croatia. Data regarding risk factors during pregnancy and early life period of the child were evaluated...
July 27, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28750335/ironphone-mobile-device-coupled-point-of-care-diagnostics-for-assessment-of-iron-status-by-quantification-of-serum-ferritin
#2
Balaji Srinivasan, Dakota O'Dell, Julia L Finkelstein, Seoho Lee, David Erickson, Saurabh Mehta
Iron deficiency (ID) is an urgent public health problem that has devastating effects on maternal and child health. However, due to poor access and affordability, screening and diagnosis for ID is often limited to proxy hemoglobin measurements alone. Here, we report the development and validation of ironPhone, a mobile-device coupled portable diagnostics for quantification of serum ferritin concentrations, an iron status biomarker, within a few minutes, from a drop of fingerprick blood. The ironPhone diagnostic platform comprises of a smartphone accessory, an app, and a disposable lateral flow immunoassay test strip to quantify serum ferritin...
July 19, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28750213/maternal-infection-and-stress-during-pregnancy-and-depressive-symptoms-in-adolescent-offspring
#3
Shannon K Murphy, Anna M Fineberg, Seth D Maxwell, Lauren B Alloy, Lauren Zimmermann, Nickilou Y Krigbaum, Barbara A Cohn, Deborah A G Drabick, Lauren M Ellman
Maternal infection during pregnancy has been linked to increased risk of offspring depression. Additionally, maternal stress during pregnancy has been consistently linked with adverse offspring outcomes associated with depression. Relatedly, stress has been associated with increased risk of infection; however no study has investigated stress-infection interactions during pregnancy and risk for offspring depression. Participants were drawn from the Child Health and Development Studies (CHDS), a prospective, longitudinal study that enrolled pregnant women from 1959 to 1966...
July 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28749705/associations-between-postpartum-depression-breastfeeding-and-oxytocin-levels-in-latina-mothers
#4
Sandraluz Lara-Cinisomo, Kathryn McKenney, Arianna Di Florio, Samantha Meltzer-Brody
BACKGROUND: Postpartum depression (PPD), often comorbid with anxiety, is the leading medical complication among new mothers. Latinas have elevated risk of PPD, which has been associated with early breastfeeding cessation. Lower plasma oxytocin (OT) levels have also been associated with PPD in non-Latinas. This pilot study explores associations between PPD, anxiety, breastfeeding, and OT in Latinas. MATERIALS AND METHODS: Thirty-four Latinas were enrolled during their third trimester of pregnancy and followed through 8 weeks postpartum...
July 27, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28749530/parents-willingness-to-invest-in-their-children-s-oral-health
#5
Jannetje Berendsen, Clarissa Bonifacio, Martine van Gemert-Schriks, Cor van Loveren, Erik Verrips, Denise Duijster
OBJECTIVES: This study aimed to evaluate parents' Willingness to Invest (WTI) in their children's oral health in terms of money, visits to a dental practice, and brushing minutes. Objectives were to assess the association between parents' WTI and a) children's dental caries experience, b) children's oral hygiene behavior (OHB), and c) maternal education level and ethnic background. METHODS: A sample of 630 five to six-year-old-children was recruited from pediatric dental centers in the Netherlands...
July 27, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28749486/milestones-and-controversies-in-maternal-and-child-health-examining-a-brief-history-of-micronutrient-fortification-in-the-us
#6
A Deavenport-Saman, A Britt, K Smith, R A Jacobs
Fortification of our food and drinking supply has decreased morbidity rates related to micronutrient deficiencies among mothers and their children, particularly during the perinatal and neonatal periods of development. The purpose of this historical review is to examine the impact of public policy changes related to micronutrient fortification. We provide a historical investigation of achievements and controversies related to iodine, vitamin D, fluoride and folic acid fortifications in our food and drinking supply...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28748774/exposure-to-parental-psychopathology-and-offspring-s-risk-of-suicide-related-thoughts-and-behaviours-a-systematic-review
#7
S M Goodday, J Shuldiner, S Bondy, A E Rhodes
AIMS: The primary objective of this systematic review was to identify and synthesise analytic studies examining the association between exposure to parental psychopathology in childhood and the nature of subsequent suicide-related thoughts (SRT) and suicide-related behaviour (SRB) (severity of ideation, planned/unplanned attempts/lethality) and to describe the direction, and magnitude of associations. The secondary objective was to determine if the associations from the primary objective differ by the type(s) and timing of parental psychopathology, sex/gender of the parent and child and is mediated by child psychiatric symptoms and family functioning...
July 27, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28748583/overall-and-abortion-related-maternal-mortality-rates-in-uruguay-over-the-past-25-years-and-their-association-with-policies-and-actions-aimed-at-protecting-women-s-rights
#8
Leonel Briozzo, Rodolfo Gómez Ponce de León, Giselle Tomasso, Anibal Faúndes
OBJECTIVE: To evaluate changes in maternal mortality rates in Uruguay over the past 25 years, as well as their distribution by cause, and their temporal relationship with social changes and Human Development Index (HDI) indicators. METHODS: Data on maternal mortality obtained directly from the Uruguayan Ministry of Public Health for the 2001 to 2015 period were analyzed together with data from the United Nations Inter-Agency Group for Child Mortality Estimation for the 1990 to 2015 period...
August 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28748335/the-broader-autism-phenotype-in-mothers-is-associated-with-increased-discordance-between-maternal-reported-and-clinician-observed-instruments-that-measure-child-autism-spectrum-disorder
#9
Eric Rubenstein, Rebecca Edmondson Pretzel, Gayle C Windham, Laura A Schieve, Lisa D Wiggins, Carolyn DiGuiseppi, Andrew F Olshan, Annie G Howard, Brian W Pence, Lisa Young, Julie Daniels
Autism spectrum disorder (ASD) diagnosis relies on parent-reported and clinician-observed instruments. Sometimes, results between these instruments disagree. The broader autism phenotype (BAP) in parent-reporters may be associated with discordance. Study to Explore Early Development data (N = 712) were used to address whether mothers with BAP and children with ASD or non-ASD developmental disabilities were more likely than mothers without BAP to 'over-' or 'under-report' child ASD on ASD screeners or interviews compared with clinician observation or overall impression...
July 26, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28748061/host-molecular-factors-and-viral-genotypes-in-the-mother-to-child-hiv-1-transmission-in-sub-saharan-africa
#10
REVIEW
Linda Chapdeleine M Mouafo, Béatrice Dambaya, Nicole N Ngoufack, Céline N Nkenfou
Maternal viral load and immune status, timing and route of delivery, viral subtype, and host genetics are known to influence the transmission, acquisition and disease progression of human immunodeficiency virus-1 (HIV-1) infection. This review summarizes the findings from published works on host molecular factors and virus genotypes affecting mother to child transmission (MTCT) in Africa and identifies the gaps that need to be addressed in future research. Articles in PubMed, Google and AIDSearch and relevant conference abstracts publications were searched...
June 23, 2017: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/28747858/smoking-and-secondhand-smoke-exposure-and-prevalence-of-depressive-symptoms-during-pregnancy-in-japan-baseline-data-from-the-kyushu-okinawa-maternal-and-child-health-study
#11
Yuri Kawasaki, Yoshihiro Miyake, Keiko Tanaka, Shinya Furukawa, Masashi Arakawa
No abstract text is available yet for this article.
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28747160/adverse-events-in-women-and-children-who-have-received-intrapartum-antibiotic-prophylaxis-treatment-a-systematic-review
#12
Farah Seedat, Chris Stinton, Jacoby Patterson, Julia Geppert, Bee Tan, Esther R Robinson, Noel Denis McCarthy, Olalekan A Uthman, Karoline Freeman, Samantha Ann Johnson, Hannah Fraser, Colin Stewart Brown, Aileen Clarke, Sian Taylor-Phillips
BACKGROUND: Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. METHODS: We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016...
July 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28746574/institutional-violence-and-quality-of-service-in-obstetrics-are-associated-with-postpartum-depression
#13
Karina Junqueira de Souza, Daphne Rattner, Muriel Bauermann Gubert
OBJECTIVE: To investigate the association between institutional violence in obstetrics and postpartum depression (PP depression) and the potential effect of race, age, and educational level in this outcome. METHODS: This is a cross-sectional study about the health care conditions for the maternal and child population of the Federal District, Brazil, carried out in 2011. The study has used a probabilistic sample of 432 women, whose children were aged up to three months, stratified by clusters...
July 20, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28746341/association-of-prenatal-exposure-to-benzodiazepines-and-child-internalizing-problems-a-sibling-controlled-cohort-study
#14
Ragnhild E Brandlistuen, Eivind Ystrom, Sonia Hernandez-Diaz, Svetlana Skurtveit, Randi Selmer, Marte Handal, Hedvig Nordeng
BACKGROUND: During pregnancy, many women experience sleep problems and anxiety that require treatment. The long-term safety for the child of maternal benzodiazepine (BZD) and z-hypnotic use during pregnancy remains controversial. METHOD: We conducted a cohort and a sibling control study using data from the Norwegian Mother and Child Cohort Study. Data on use of BZD and z-hypnotics, internalizing and externalizing outcomes, and covariates were collected from mothers at gestational weeks 17 and 30 and when children were 0...
2017: PloS One
https://www.readbyqxmd.com/read/28746325/effect-of-maternal-socio-demographic-factors-and-child-feeding-practice-on-wasting-among-under-five-years-children-in-slum-area-of-rupandehi-district-in-nepal
#15
S Gautam, S Ruchal, B Timalsina, D Acharya, B Khadka, V Gautam, J K Singh
INTRODUCTION: Childhood wasting although well studied elsewhere, it has not been well understood about in slum area of Nepal. This study aimed to assess effect of socio-demographic factors and child feeding practice in the determination of wasting among the children under five years of age in slum area of Nepal. METHODS: A community based cross-sectional study was performed among 150 children under five years of age from the slum area of Nepal between 1st January and 28th February 2013 using simple random sampling techniques...
April 2017: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28746086/hiv-drug-resistance-in-infants-increases-with-changing-prevention-of-mother-to-child-transmission-regimens
#16
Lisa K Poppe, Catherine Chunda-Liyoka, Eun H Kwon, Clement Gondwe, John T West, Chipepo Kankasa, Clement B Ndongmo, Charles Wood
OBJECTIVES: The objectives of this study were to determine HIV drug resistance (HIVDR) prevalence in Zambian infants upon diagnosis, and to determine how changing prevention of mother-to-child transmission (PMTCT) drug regimens affect drug resistance. DESIGN: Dried blood spot (DBS) samples from infants in the Lusaka District of Zambia, obtained during routine diagnostic screening, were collected during four different years representing three different PMTCT drug treatment regimens...
August 24, 2017: AIDS
https://www.readbyqxmd.com/read/28744935/emergency-department-presentations-in-infants-predictors-from-an-australian-birth-cohort
#17
Julia Crilly, Cate M Cameron, Paul A Scuffham, Norm Good, Rani Scott, Gabor Mihala, Amy Sweeny, Gerben Keijzers
AIM: Infants under 12 months of age are disproportionately represented amongst emergency department (ED) presentations, and infants are more likely to be frequent ED users. This study aimed to describe and identify psychosocial predictors of ED presentation in infants. METHODS: A prospective birth cohort from Queensland and New South Wales (Environments for Healthy Living) was used to understand infant health service use. Baseline and 12-month questionnaire data pertaining to children born between 2006 and 2011 were used to identify predictors of ED presentation, using multiple regression analysis...
July 25, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28744795/prediction-of-fetal-darunavir-exposure-by-integrating-human-ex-vivo-placental-transfer-and-physiologically-based-pharmacokinetic-modeling
#18
Stein Schalkwijk, Aaron O Buaben, Jolien J M Freriksen, Angela P Colbers, David M Burger, Rick Greupink, Frans G M Russel
BACKGROUND: Fetal antiretroviral exposure is usually derived from the cord-to-maternal concentration ratio. This static parameter does not provide information on the pharmacokinetics in utero, limiting the assessment of a fetal exposure-effect relationship. OBJECTIVE: The aim of this study was to incorporate placental transfer into a pregnancy physiologically based pharmacokinetic model to simulate and evaluate fetal darunavir exposure at term. METHODS: An existing and validated pregnancy physiologically based pharmacokinetic model of maternal darunavir/ritonavir exposure was extended with a feto-placental unit...
July 25, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28742825/impact-of-maternal-and-neonatal-health-initiatives-on-inequity-in-maternal-health-care-utilization-in-bangladesh
#19
Mohammad Rifat Haider, Mohammad Masudur Rahman, Md Moinuddin, Ahmed Ehsanur Rahman, Shakil Ahmed, M Mahmud Khan
BACKGROUND: Despite remarkable progress in maternal and child health, inequity persists in maternal care utilization in Bangladesh. Government of Bangladesh (GOB) with technical assistance from United Nation Population Fund (UNFPA), United Nation Children's Fund (UNICEF) and World Health Organization (WHO) started implementing Maternal and Neonatal Health Initiatives in selected districts of Bangladesh (MNHIB) in 2007 with an aim to reduce inequity in healthcare utilization. This study examines the effect of MNHIB on inequity in maternal care utilization...
2017: PloS One
https://www.readbyqxmd.com/read/28741262/maternal-mental-quality-of-life-mediates-the-associations-between-intimate-partner-abuse-against-mothers-and-their-children-s-behaviours-and-quality-of-life-in-low-income-chinese-families
#20
Vivian Yawei Guo, Esther Yee Tak Yu, Rosa Sze Man Wong, Patrick Ip, Agnes Fung Yee Tiwari, Carlos King Ho Wong, Colman Siu Cheung Fung, Wilfred Hing Sang Wong, Cindy Lo Kuen Lam
PURPOSE: To explore the association between maternal intimate partner abuse (IPA) and their children's health-related quality of life (HRQOL) and behavioural problem, and to establish a mediation model and investigate the mediating role of mothers' HRQOL on this association. METHODS: A cross-sectional study was conducted on 197 mothers of 227 children (112 boys and 115 girls) from low-income Chinese families. The mothers were asked to complete the 5-item abuse assessment screen questionnaire for the presence of IPA, the Chinese (Hong Kong) version of 12-item Short-Form Health Survey (SF-12) for their HRQOL and a structured socio-demographics questionnaire...
July 24, 2017: Quality of Life Research
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