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cat scratch disease

David Dornbos, Jocelyn Morin, Joshua R Watson, Jonathan Pindrik
Osteomyelitis of the spine with associated spinal epidural abscess represents an uncommon entity in the pediatric population, requiring prompt evaluation and diagnosis to prevent neurological compromise. Cat scratch disease, caused by the pathogen Bartonella henselae, encompasses a wide spectrum of clinical presentations; however, an association with osteomyelitis and epidural abscess has been reported in only 4 other instances in the literature. The authors report a rare case of multifocal thoracic osteomyelitis with an epidural abscess in a patient with a biopsy-proven pathogen of cat scratch disease...
September 23, 2016: Journal of Neurosurgery. Pediatrics
Christina A Nelson, Shubhayu Saha, Paul S Mead
Cat-scratch disease (CSD) is mostly preventable. More information about the epidemiology and extent of CSD would help direct prevention efforts to those at highest risk. To gain such information, we reviewed the 2005-2013 MarketScan national health insurance claims databases and identified patients <65 years of age with an inpatient admission or outpatient visit that included a CSD code from the International Classification of Diseases, Ninth Revision, Clinical Modification. Incidence of CSD was highest among those who lived in the southern United States (6...
October 2016: Emerging Infectious Diseases
E Rossi, A Perrone, D Narese, M Cangelosi, S Sollai, A Semeraro, M Mortilla, C Defilippi
Cat-scratch disease (CSD) is a zoonosis in children, result of infection by Bartonella henselae, a gram-negative bacillus. Infection is generally characterized by regional and self-limited lymphadenopathy after exposure to a scratch or bite from a cat. Rarely, B. henselae is cause of fever of unknown origin (FUO), with dissemination to various organs, most often involving the reticuloendothelial system (liver, spleen, bone marrow), mimicking an inflammatory rather than a lymphoproliferative disease. Whole-body Magnetic Resonance Imaging (WBMRI), in association with diffusion-weighted imaging (DWIBS), allows a comprehensive evaluation of pediatric patients, without the risks inherent to ionizing radiation...
July 2016: La Clinica Terapeutica
Sean K Verma, Angel Martin, Jose A Montero
No abstract text is available yet for this article.
July 30, 2016: Clinical Gastroenterology and Hepatology
Aleksandra Krasowska-Kwiecień, Jolanta Goździk, Magdalena Woźniak, Wojciech Czogała
Infections in immunocompromised patients after hematopoietic stem cell transplantation can have a severe and atypical course. Some opportunistic pathogens are difficult to detect in microbiological tests, and that is why treatment success depends on an accurate clinical diagnosis. This article presents a case of a 7-year-old girl with severe aplastic anemia treated with bone marrow transplantation with post-transplantation period complicated by persistent, hectic fever, with peak episodes of 39-40°C, lasting several weeks...
June 2016: Journal of Ultrasonography
Juan Carlos García García, Manuel Jesús Núñez Fernández, Aránzazu Portillo Barrio, José Antonio Oteo Revuelta
No abstract text is available yet for this article.
July 14, 2016: Enfermedades Infecciosas y Microbiología Clínica
Azin Abazari, Kevin Kaplowitz, Patrick Sibony
We report a case of bilateral multifocal retinochoroiditis and bilateral optic disc edema in a patient with cat-scratch disease from Bartonella henselae. The patient initially had negative serologic testing. Repeat testing showed a markedly increased IgG and IgM convalescent titer and the development of a branch retinal artery and vein occlusion. In patients for whom there is a high clinical suspicion of cat-scratch disease, a convalescent titer should be obtained 2-3 weeks following a negative initial result...
2015: Digital Journal of Ophthalmology: DJO
Serkan Feyyaz Yalin, Serdar Sahin, Mucahit Yemisen, Nukhet Tuzuner, Mehmet Riza Altiparmak, Nurhan Seyahi
Cat scratch disease (CSD) is a disorder characterized by self-limited regional lymphadenopathy and fever. We reported a case of CSD in a kidney transplant recipient who presented with fever and lymphadenopathy. Lymph node biopsy demonstrated bacterial histiocytic lymphadenitis. The patient was diagnosed with CSD. Patient had good clinical improvement after treatment. Therefore, CSD should also be borne in mind for kidney recipients though CSD had been infrequently reported in this group.
September 2016: Progress in Transplantation
Rosario Cerpa Polar, Gabriela Orellana, Wilmer Silva Caso, José Sánchez Carbonel, Javier Santisteban, Juana Del Valle Mendoza, Javier Santisteban
Cat scratch's disease caused by Bartonella henselae, is known to be a self-limited benign process in immunocompetent children. The association with neurologic manifestations is very uncommon especially in patient with no immunologic defects and in cases without specific treatment. A 7 years old male patient, without any immunocompromised defect, presented an atypic presentation of the cat scratch disease. The patient came to the hospital in two opportunities in a status epilepticus, in both cases the diagnosis was encephalitis by Bartonella henselae and the evolution with treatment was monitored with PCR (polymerase chain reaction) in cerebrospinal fluid and blood, as well as IFI (IgM, IgG) serology (indirect immunofluorescence)...
June 2016: Asian Pacific Journal of Tropical Medicine
Aaron Rohr, Ryan Ash, John Vadaparampil, Jacqueline Hill, Louis Wetzel
A 51-year-old man with history of undiagnosed pulmonary nodules 4 years prior, presented with right-sided chest pain. Acute cardiac workup was negative, and a chest computed tomography examination demonstrated marked improvement in bilateral pulmonary nodules. A concordant abdominal computed tomography examination showed new subcentimeter hypodense lesions throughout the liver and spleen, mild progressive abdominopelvic lymphadenopathy, and new small lytic lesions of T11 and L4 vertebrae. A positron emission tomography examination demonstrated hypermetabolic activity of these abdominopelvic lesions suggesting metastatic disease...
June 2016: Radiology case reports
Ramin Mazaheri Nezhad Fard, Seyed Milad Vahedi, Iraj Ashrafi, Faranak Alipour, Golnaz Sharafi, Hesam Akbarein, Seyed Javid Aldavood
One of the most important species of the Bartonella genus is B. henselae that causes a zoonotic infection, cat scratch disease (CSD). The main source of the bacteria is cat and the carrier is Ctenocephalides felis flea. One hundred and forty nail and saliva samples were collected from 70 domestic cats. Positive samples for B. henselae were characterized by polymerase chain reaction (PCR) and sequencing. Sequences of gltA gene were trimmed using BioEdit software and then compared with the sequences of the same gene from B...
2016: Veterinary Research Forum
Wojciech Świątkowski, Mansur Rahnama, Katarzyna Strzelczyk, Jakub Baszak, Jadwiga Sierocińska-Sawa
Cat scratch disease (CSD) - bartonellosis, is zoonosis caused by the intracellular gram negativebacterium Bartonellahenselae or Bartonellaquintana. The pathogens of this disease enter the human body usually as a consequence of a bite or scratch by young cats which are the natural source of such bacteria. The illness proceeds asymptomatically or with topical symptoms of infection such as a lump, spot or blister. Within 14 days a high fever and topical lymphadenopathy are observed. Lymph nodes are sore and start suppurating...
March 1, 2016: Polski Przeglad Chirurgiczny
Stephanie A Bernard, Eric A Walker, John F Carroll, Mary Klassen-Fischer, Mark D Murphey
OBJECTIVE: Evaluate anatomic and imaging features of epitrochlear regional adenopathy secondary to cat scratch disease (CSD) to assist differentiation of CSD from other soft tissue masses at the elbow. MATERIALS AND METHODS: Retrospective review of 24 confirmed cases of CSD. Patient demographics, clinical presentation and radiographic (R; n = 10), CT (n = 3), ultrasound (US; n = 5), and MR (n = 21) images were reviewed. Lesion location, size, number of masses, and intrinsic characteristics on R/CT/US/MR and presence of soft tissue inflammatory changes or adjacent bone or joint involvement were established through the consensus interpretation by four musculoskeletal radiologists...
September 2016: Skeletal Radiology
Manuel Alamán Valtierra, Carmen Simón Valencia, Hector Fuertes Negro, Amaya Unzueta Galarza, Byron Flores Somarriba, Nabil Halaihel Kassab
OBJECTIVE: Bartonella henselae is responsible for the Cat Scratch Disease in humans, being it underdiagnosed. This study aims to detect and quantify the load of B. henselae DNA in oral and whole blood samples from stray and shelthered cats from Zaragoza (Spain), and analyze associations with epidemiological and clinical factors. METHODS: 47 cats entered in the estudy. Real time PCR was used to detect B. henselae DNA in blood and oral samples. The SPSS software was applied to the statistical analysis of positivity of paired samples and its relationship with variables as age, sex, origin, month of sampling and fleas/ticks observation in fur and clinical factors (health status and observation of oral lesions)...
2016: Revista Española de Salud Pública
Chih-Chen Chang, Chia-Jie Lee, Liang-Shiou Ou, Chao-Jan Wang, Yhu-Chering Huang
Cat scratch disease (CSD) can present as a systemic disease in 5-10% of cases and lead to various disease entities. A previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. Abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. Despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. Inguinal lymph node biopsy confirmed CSD by immunohistochemistry staining...
January 12, 2016: Paediatrics and International Child Health
Hesamaddin Shirzad Aski, Mohammad Tabatabaei
Pasteurella multocida infects a wide range of animals and the infection may spread to human through animal bites and scratches. Pasteurella multocida isolates, obtained from several clinically healthy and diseased animals (bovine, sheep, goat, poultry, dog and cat), were investigated for capsule biosynthesis (capA, B, D, E and F) and expression of 22 virulence-associated genes using Polymerase Chain Reaction (PCR). Multiplex PCR results revealed expression of capA, capD and capB genes in 81 (61.83%), 30 (22...
July 2016: Microbial Pathogenesis
Yoshihiro Aoki, Katsuhiko Kitazawa
No abstract text is available yet for this article.
2016: IDCases
Catriona MacPhail
Ear disease, such as otitis externa, resulting in aggressive head shaking or ear scratching, is the most common cause of the development of aural hematomas in dogs and cats. An underlying immunologic cause has also been proposed to explain cartilage and blood vessel fragility. Numerous options exist for management of aural hematomas, from medical management alone with corticosteroids, to simple hematoma centesis, to surgical intervention. Because this condition is usually secondary to another disease process, regardless of mode of treatment, likelihood of recurrence is low if the underlying condition is managed properly...
July 2016: Veterinary Clinics of North America. Small Animal Practice
Maurizio Mennini, Diletta Valentini, Chiara DI Camillo, Anna C Vittucci, Annalisa Grandin, Laura Lancella, Andrea Bartuli, Alberto Villani
BACKGROUND: Symptomatic Bartonella henselae infection is considered rare in Europe. Cat fleas transmit the microorganism between cats, but their role in transmission of B. henselae to humans has not been defined. The aim of our study was to perform a retrospective study of detected cases at our Hospital. METHODS: We retrospectively analyzed data of all children showing lymphoadenopathy and a 4-fold increase in specific IgM for B.henselae over the period from June 2010 to May 2015...
March 23, 2016: Minerva Pediatrica
Pedro Paulo Vissotto de Paiva Diniz, Paulo Eduardo Neves Ferreira Velho, Luiza Helena Urso Pitassi, Marina Rovani Drummond, Bruno Grosselli Lania, Maria Lourdes Barjas-Castro, Stanley Sowy, Edward B Breitschwerdt, Diana Gerardi Scorpio
Bacteria from the genus Bartonella are emerging blood-borne bacteria, capable of causing long-lasting infection in marine and terrestrial mammals, including humans. Bartonella are generally well adapted to their main host, causing persistent infection without clinical manifestation. However, these organisms may cause severe disease in natural or accidental hosts. In humans, Bartonella species have been detected from sick patients presented with diverse disease manifestations, including cat scratch disease, trench fever, bacillary angiomatosis, endocarditis, polyarthritis, or granulomatous inflammatory disease...
March 2016: PLoS Neglected Tropical Diseases
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