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https://www.readbyqxmd.com/read/28645214/sodium-fluorescein-facilitates-guided-sampling-of-diagnostic-tumor-tissue-in-nonenhancing-gliomas
#1
Stephen G Bowden, Justin A Neira, Brian J A Gill, Timothy H Ung, Zachary K Englander, George Zanazzi, Peter D Chang, Jorge Samanamud, Jack Grinband, Sameer A Sheth, Guy M McKhann, Michael B Sisti, Peter Canoll, Randy S D'Amico, Jeffrey N Bruce
BACKGROUND: Accurate tissue sampling in nonenhancing (NE) gliomas is a unique surgical challenge due to their intratumoral histological heterogeneity and absence of contrast enhancement as a guide for intraoperative stereotactic guidance. Instead, T2/fluid-attenuated inversion-recovery (FLAIR) hyperintensity on MRI is commonly used as an imaging surrogate for pathological tissue, but sampling from this region can yield nondiagnostic or underdiagnostic brain tissue. Sodium fluorescein is an intraoperative fluorescent dye that has a high predictive value for tumor identification in areas of contrast enhancement and NE in glioblastomas...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28645182/stereotactic-radiosurgery-for-brainstem-arteriovenous-malformations-a-multicenter-study
#2
Or Cohen-Inbar, Robert M Starke, Cheng-Chia Lee, Hideyuki Kano, Paul Huang, Douglas Kondziolka, Inga S Grills, Danilo Silva, Mohmoud Abbassy, Symeon Missios, Gene H Barnett, L Dade Lunsford, Jason P Sheehan
BACKGROUND: The management of brainstem arteriovenous malformations (bAVMs) is a formidable challenge. bAVMs harbor higher morbidity and mortality compared to other locations. OBJECTIVE: To review the outcomes following stereotactic radiosurgery (SRS) of bAVMs in a multicenter study. METHODS: Six medical centers contributed data from 205 patients through the International Gamma Knife Research Foundation. Median age was 32 yr (6-81). Median nidus volume was 1...
June 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28644200/electrical-stimulations-of-the-human-insula-their-contribution-to-the-ictal-semiology-of-insular-seizures
#3
Laure Mazzola, François Mauguière, Jean Isnard
INTRODUCTION: Stereotactic stimulations of the insular cortex through intracranial electrodes aim at characterizing the semiology of insular seizures. These stimulations, carried out in the context of Stereo-Electro-Encephalography (SEEG) during presurgical monitoring of epilepsy, reproduce the ictal symptoms observed during the development of insular seizures. METHODS: The authors reviewed the results of insular stimulations performed in 222 patients admitted between 1997 and 2015 for presurgical SEEG exploration of atypical temporal or perisylvian epilepsy...
July 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28644075/spine-stereotactic-radiosurgery-for-metastatic-sarcoma-patterns-of-failure-and-radiation-treatment-volume-considerations
#4
Andrew J Bishop, Randa Tao, B Ashleigh Guadagnolo, Pamela K Allen, Neal C Rebueno, Xin A Wang, Behrang Amini, Claudio E Tatsui, Laurence D Rhines, Jing Li, Eric L Chang, Paul D Brown, Amol J Ghia
OBJECTIVE Given the relatively lower radiosensitivity of sarcomas and the locally infiltrative patterns of spread, the authors sought to investigate spine stereotactic radiosurgery (SSRS) outcomes for metastatic sarcomas and to analyze patterns of failure. METHODS The records of 48 patients with 66 sarcoma spinal metastases consecutively treated with SSRS between 2002 and 2013 were reviewed. The Kaplan-Meier method was used to estimate rates of overall survival (OS) and local control (LC). Local recurrences were categorized as occurring infield (within the 95% isodose line [IDL]), marginally (between the 20% and 95% IDLs), or out of field...
June 23, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28643878/frameless-stereotactic-radiotherapy-alone-and-combined-with-temozolomide-for-presumed-canine-gliomas
#5
M Dolera, L Malfassi, C Bianchi, N Carrara, S Finesso, S Marcarini, G Mazza, S Pavesi, M Sala, G Urso
We evaluated stereotactic volume modulated arc radiotherapy (VMAT) for canine gliomas, alone (radiotherapy [RT]) and in combination with temozolomide (RT + TMZ), compared with palliation. Overall and disease-specific survival times were estimated. Thirty dogs were palliated, 22 dogs were treated with RT and 20 with RT + TMZ. Complete and partial responses were observed in 63.2% and 90.9% of patients in the RT and RT + TMZ arms, respectively, that were alive at 1 year. Median survival in the palliation arm was 94 days (95% conformity index [CI] 87÷101)...
June 23, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28643730/an-overview-on-small-field-dosimetry-in-photon-beam-radiotherapy-developments-and-challenges
#6
REVIEW
Hamed Bagheri, Azadeh Soleimani, Nahideh Gharehaghaji, Asghar Mesbahi, Farhad Manouchehri, Babak Shekarchi, Banafsheh Dormanesh, Habib Alah Dadgar
Small fields are more repeatedly used for radiation therapy as small segments in intensity-modulated radiotherapy or as in the form of independent fields in stereotactic radiosurgery and other novel equipment such as cyberknife and tomotherapy. Nevertheless, the application of small fields for radiotherapy of lung makes the dose calculation and planning inaccurate due to the existence of electronic disequilibrium and intrinsic deficiencies within most of the analytical dose calculation algorithms. The current review attempts to gather the information in this regard and focuses on the current progresses and retaining issues associated with this type of photon beams...
April 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28643523/management-of-quadrigeminal-arachnoid-cyst-associated-with-obstructive-hydrocephalus-report-on-stereotactic-ventricular-cystic-stenting
#7
Yosef Laviv, Sergio Neto, Ekkehard M Kasper
Quadrigeminal arachnoid cysts (QAC) are usually accompanied by a symptomatic obstructive hydrocephalus. Several endoscopic and surgical treatments exist; however, the critical location of these cysts further complicates treatment and usually more than one procedure is required. In this report, a 31 year old female with QAC and associated obstructive hydrocephalus was successfully treated with stereotactic placement of a permanent ventricular - cystic stent (intraventricualr - cystic catheterization) in single - session...
June 23, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28642817/cerebral-vasculitis-mimicking-intracranial-metastatic-progression-of-lung-cancer-during-pd-1-blockade
#8
Heinz Läubli, Jürgen Hench, Michal Stanczak, Ingmar Heijnen, Alexandros Papachristofilou, Stephan Frank, Alfred Zippelius, Frank Stenner-Liewen
BACKGROUND: Stimulation of the immune system by targeting the PD-1/PD-L1 pathway can result in activation of anti-tumor immunity. Besides its clinical benefit immune checkpoint therapy leads to significant immune-related adverse events (irAEs). Some rare irAEs are not well described yet but are critical in patient management. CASE PRESENTATION: Here, we describe a case of autoimmune cerebral vasculitis/encephalitis after PD-1 inhibitor treatment for metastatic adenocarcinoma of the lung...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28642352/management-of-brain-arteriovenous-malformations-a-scientific-statement-for-healthcare-professionals-from-the-american-heart-association-american-stroke-association
#9
REVIEW
Colin P Derdeyn, Gregory J Zipfel, Felipe C Albuquerque, Daniel L Cooke, Edward Feldmann, Jason P Sheehan, James C Torner
PURPOSE: The aim of this statement is to review the current data and to make suggestions for the diagnosis and management of both ruptured and unruptured brain arteriovenous malformations. METHODS: The writing group met in person and by teleconference to establish search terms and to discuss narrative text and suggestions. Authors performed their own literature searches of PubMed, Medline, or Embase, specific to their allocated section, through the end of January 2015...
June 22, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28641280/17th-quadrennial-meeting-of-the-world-society-for-stereotactic-and-functional-neurosurgery-berlin-germany-june-26-29-2017-abstracts
#10
(no author information available yet)
No abstract text is available yet for this article.
June 22, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28640703/integrating-evidence-based-medicine-for-treatment-of-spinal-metastases-into-a-decision-framework-neurologic-oncologic-mechanicals-stability-and-systemic-disease
#11
Ori Barzilai, Ilya Laufer, Yoshiya Yamada, Daniel S Higginson, Adam M Schmitt, Eric Lis, Mark H Bilsky
Patients with cancer are frequently affected by spinal metastases. Treatment is palliative, with the principle goals of pain relief, preservation of neurologic function, and improvement in quality of life. In the past decade, we have witnessed a dramatic change in the treatment paradigms due to the development of improved surgical strategies and systemic and radiation therapy. The most important change to these paradigms has been the integration of spinal stereotactic radiosurgery (SSRS), allowing delivery of tumoricidal radiation doses with sparing of nearby organs at risk...
June 22, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28639387/determining-the-orientation-angle-of-directional-leads-for-deep-brain-stimulation-using-computed-tomography-and-digital-x-ray-imaging-a-phantom-study
#12
Alexander Sitz, Mauritius Hoevels, Alexandra Hellerbach, Andreas Gierich, Klaus Luyken, Till A Dembek, Martin Klehr, Jochen Wirths, Veerle Visser-Vandewalle, Harald Treuer
PURPOSE: Orientating the angle of directional leads for deep brain stimulation (DBS) in an axial plane introduces a new degree of freedom that is indicated by embedded anisotropic directional markers. Our aim was to develop algorithms to determine lead orientation angles from computed tomography (CT) and stereotactic x-ray imaging using standard clinical protocols, and subsequently assess the accuracy of both methods. METHODS: In CT the anisotropic marker artifact was taken as a signature of the lead orientation angle and analyzed using discrete Fourier transform of circular intensity profiles...
June 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28639133/stereotactic-biopsy-in-elderly-patients-risk-assessment-and-impact-on-treatment-decision
#13
Stephanie G Kellermann, Christina A Hamisch, Daniel Rueß, Tobias Blau, Roland Goldbrunner, Harald Treuer, Stefan J Grau, Maximilian I Ruge
To evaluate risk profile, diagnostic yield and impact on treatment decision of stereotactic biopsy (SB) in elderly patients with unclear cerebral lesions. In this single center retrospective analysis we identified all patients aged ≥70 years receiving SB between January 2005 and December 2015. Demographic data, Karnofsky Performance Status (KPS), histology, comorbidity (by CHA2DS2-VASc Score) and use of anticoagulation were retrieved. We scrutinized diagnostic yield, procedural complications (mortality, transient and permanent morbidity), hospitalization time and therapeutic consequence...
June 21, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28638802/target-migration-from-re-inflation-of-adjacent-atelectasis-during-lung-stereotactic-body-radiotherapy
#14
Bijing Mao, Vivek Verma, Dandan Zheng, Xiaofeng Zhu, Nathan R Bennion, Abhijeet R Bhirud, Maria A Poole, Weining Zhen
Stereotactic body radiotherapy (SBRT) is a widely accepted option for the treatment of medically inoperable early-stage non-small cell lung cancer (NSCLC). Herein, we highlight the importance of interfraction image guidance during SBRT. We describe a case of early-stage NSCLC associated with segmental atelectasis that translocated 15 mm anteroinferiorly due to re-expansion of the adjacent segmental atelectasis following the first fraction. The case exemplifies the importance of cross-sectional image-guided radiotherapy that shows the intended target, as opposed to aligning based on rigid anatomy alone, especially in cases associated with potentially "volatile" anatomic areas...
June 10, 2017: World Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28637635/stereotactic-bilateral-transfrontal-minimal-radiofrequency-thermocoagulation-of-the-amygdalohippocampal-complex-for-bilateral-medial-temporal-lobe-epilepsy-a-retrospective-study-of-12-patients
#15
Quanjun Zhao, Tiejun Shi, Shaojie Cui, Zhaohui Wu, Wei Wang, Yunfeng Jia, Zengmin Tian, Fuli Wang, Feng Yin, Hulin Zhao, Xia Xiao, Haiying Wang, Changlan Cai, Huimin Luo
Some patients with temporal lobe epilepsy have bilateral discharges and a few have bilateral medial temporal sclerosis. Stereotactic bilateral radiofrequency thermocoagulation (RFTC) of the amygdalohippocampal complex can terminate seizures or reduce seizure severity in patients with bilateral medial temporal lobe epilepsy (BMTLE). To explore the safety and efficacy of bilateral transfrontal minimal RFTC of the amygdalohippocampal complex for the treatment of BMTLE. A total of 12 BMTLE patients were treated with bilateral transfrontal minimal RFTC of the amygdalohippocampal complex under limited coagulations...
June 19, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28637480/institutional-analysis-of-stereotactic-body-radiotherapy-sbrt-for-oligometastatic-lymph-node-metastases
#16
Rosanna Yeung, Jeremy Hamm, Mitchell Liu, Devin Schellenberg
BACKGROUND: In limited metastatic burden of disease, stereotactic body radiotherapy (SBRT) has been shown to achieve high local control rates. It has been hypothesized that SBRT may translate to a better quality of life by delaying the need for systemic chemotherapy and possibly increasing survival. There is limited published literature on the efficacy of SBRT in limited nodal metastases. The primary aim is to review institutional outcomes of patients with solitary or oligometastatic lymph nodes treated with SBRT...
June 21, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28636658/efficacy-and-safety-of-ultrasound-guided-implantation-of-fiducial-markers-in-the-liver-for-stereotactic-body-radiation-therapy
#17
So Hyun Park, Hyung Jin Won, So Yeon Kim, Yong Moon Shin, Pyo Nyun Kim, Sang Min Yoon, Jin-Hong Park, Jong Hoon Kim
OBJECTIVE: Stereotactic body radiation therapy (SBRT) for the treatment of a malignancy in the liver requires the perilesional implantation of fiducial markers for lesion detection. The purpose of this study is to evaluate the efficacy and safety of ultrasound (US) -guided marker implantation for SBRT. METHODS: We retrospectively reviewed 299, US-guided, intrahepatic fiducial markers implanted in 101 patients between November 2013 and September 2014. SBRT-planning CT images were analyzed to determine the technical success of the implantation, the mean distance between the tumor margin and the marker, with the ideal location of fiducials defined as the distance between a marker and a tumor less than 3 cm and the distance between markers greater than 2 cm according to the tumor conspicuity seen on gray-scale US and the artifact obscuring tumor margins...
2017: PloS One
https://www.readbyqxmd.com/read/28636530/gamma-analysis-with-a-gamma-criterion-of-2-1-mm-for-stereotactic-ablative-radiotherapy-delivered-with-volumetric-modulated-arc-therapy-technique-a-single-institution-experience
#18
Jung-In Kim, Minsoo Chun, Hong-Gyun Wu, Eui Kyu Chie, Hak Jae Kim, Jin Ho Kim, Jong Min Park
To report a single-institution experience of gamma evaluations with 2%/1 mm for stereotactic ablative radiotherapy (SABR) delivered with volumetric modulated arc therapy (VMAT) technique, from January 2014 to January 2016. A total of 168 SABR VMAT plans were analyzed with a gamma criterion of 2%/1 mm, a threshold value of 10%, and a tolerance level of 90%. Of the 168 cases, four cases failed with 2%/1 mm. The average passing rate was 97.0% ± 2.5%. Three of the four failed cases showed passing rates higher than 90%, which was achieved by shifting the measuring device by 1 mm in the left-to-right or anterior-to-posterior directions...
June 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28633510/in-reply-stereotactic-radiosurgery-for-cystic-vestibular-schwannomas
#19
Michael J Link
No abstract text is available yet for this article.
June 17, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28633492/letter-stereotactic-radiosurgery-for-cystic-vestibular-schwannomas
#20
Eduardo de Arnaldo Silva Vellutini, Matheus Fernandes de Oliveira
No abstract text is available yet for this article.
June 17, 2017: Neurosurgery
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