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https://www.readbyqxmd.com/read/28231414/mir-135a-3p-as-a-promising-biomarker-and-nucleic-acid-therapeutic-agent-for-ovarian-cancer
#1
Satoshi Fukagawa, Kohei Miyata, Fusanori Yotsumoto, Chihiro Kiyoshima, Sung Ouk Nam, Haruchika Anan, Takahiro Katsuda, Daisuke Miyahara, Masaharu Murata, Hiroshi Yagi, Kyoko Shirota, Shin'ichiro Yasunaga, Kiyoko Kato, Shingo Miyamoto
Ovarian cancer is the most lethal gynecologic malignancy. Recently, several molecularly targeted anticancer agents have been developed for ovarian cancer; however, its prognosis has remained extremely poor. The development of molecularly targeted therapy, as well as companion diagnostics, is required to improve outcomes for patients with ovarian cancer. In this study, to identify microRNAs involved in the progression of ovarian cancer we analyzed serum microRNAs in patients with ovarian cancer using microRNA array and qRT-PCR and examined the anticancer properties of microRNA expression in ovarian cancer cells...
February 23, 2017: Cancer Science
https://www.readbyqxmd.com/read/28231361/thyroglossal-duct-cyst
#2
Lester D Thompson
No abstract text is available yet for this article.
February 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28229914/quercetin-exerts-preventive-ameliorative-and-prophylactic-effects-on-cadmium-chloride-induced-oxidative-stress-in-the-uterus-and-ovaries-of-female-wistar-rats
#3
Victor Udo Nna, Umar Zayyanu Usman, Emmanuel Oleba Ofutet, Daniel Udofia Owu
This study examined the possible protective effect of quercetin(QE) on cadmium chloride (CdCl2) - induced reproductive toxicity in female rats. Cadmium accumulated in the uterus and ovaries of rats, decreased antioxidants [superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione (GSH)], and raised the concentrations of malondialdehyde (MDA) and hydrogen peroxide (H2O2) in the uterus and ovaries of rats. Serum concentrations of estradiol, progesterone, follicle stimulating hormone and luteinizing hormone decreased significantly after CdCl2 administration...
February 13, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28229291/a%C3%A2-patient-with-myasthenia-gravis-and-a%C3%A2-large-arachnoid-cyst-report-of-a%C3%A2-case
#4
Mira Bucuk, Iva Gasparovic, Ivan Sonnenschein, Olivio Perkovic
Myasthenia gravis is a chronic autoimmune disease characterized by weakening of voluntary muscles during the day and a marked restitution of function during the night and after rest. The symptoms may worsen over days or weeks, sometimes even in a few hours, and are usually well controlled by appropriate therapy. Arachnoid cysts are congenital or acquired deformities of the arachnoid membrane and are usually too small to cause distinct clinical symptomatology. We describe a case of a 76-year-old myasthenia gravis patient with an arachnoid cyst...
February 22, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28229165/-nasopharyngeal-cyst-of-the-respiratory-epithelium-in-a-9-year-old-yorkshire-terrier
#5
Alexander Acker, Cetina Thiel, Kernt Köhler, Kerstin von Pückler, Andreas Moritz, Martin Kramer
In a 9-year-old Yorkshire terrier a cyst of the respiratory epithelium of the nasopharynx was diagnosed. A complete obstruction of the nasopharynx leading to dyspnea was detected by computed tomography and endoscopy. A minimally invasive ablation of the cystic wall was performed under endoscopic guidance, followed by a pathohistological examination. Immediately after resection of the cyst, the clinical symptoms resolved. The follow-up endoscopical examination 3 months postoperatively was unremarkable. In the presented case the minimally invasive endoscopic ablation of the cystic wall was a successful treatment method...
February 23, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28229098/an-unusual-cause-of-pediatric-dysphagia-bronchogenic-cyst
#6
Abha Kaistha, Jeremiah Levine
No abstract text is available yet for this article.
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28229045/occurrence-of-giardia-cryptosporidium-and-entamoeba-in-wild-rhesus%C3%A2-macaques-macaca-mulatta-living-in-urban-and-semi-rural-north-west-india
#7
John J Debenham, Kristoffer Tysnes, Sandhya Khunger, Lucy J Robertson
Giardia duodenalis, Cryptosporidium spp., and Entamoeba spp. are intestinal protozoa capable of infecting a range of host species, and are important causes of human morbidity and mortality. Understanding their epidemiology is important, both for public health and for the health of the animals they infect. This study investigated the occurrence of these protozoans in rhesus macaques (Macaca mulatta) in India, with the aim of providing preliminary information on the potential for transmission of these pathogens between macaques and humans...
April 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28229043/detection-and-molecular-characterization-of-the-mosquito-borne-filarial-nematode-setaria-tundra-in-danish-roe-deer-capreolus-capreolus
#8
Heidi Larsen Enemark, Antti Oksanen, Mariann Chriél, Jakob le Fèvre Harslund, Ian David Woolsey, Mohammad Nafi Solaiman Al-Sabi
Setaria tundra is a mosquito-borne filarial nematode of cervids in Europe. It has recently been associated with an emerging epidemic disease causing severe morbidity and mortality in reindeer and moose in Finland. Here, we present the first report of S. tundra in six roe deer (Capreolus capreolus) collected between October 2010 and March 2014 in Denmark. The deer originated from various localities across the country: the eastern part of the Jutland peninsular and four locations on the island Zealand. With the exception of one deer, with parasites residing in a transparent cyst just under the liver capsule, worms (ranging from 2 to >20/deer) were found free in the peritoneal cavity...
April 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28228944/semi-closed-surgical-technique-for-treatment-of-pilonidal-sinus-disease
#9
Georgios Sahsamanis, Stavros Samaras, Georgios Mitsopoulos, Titos Deverakis, Georgios Dimitrakopoulos, Dionysios Pinialidis
INTRODUCTION: Pilonidal sinus disease (PSD) is a highly debatable disorder regarding its surgical management, despite an assortment of surgical techniques described in the medical literature. The aim of this report is to provide an alternate semi-closed surgical method for treatment of PSD, with early recovery and a satisfactory cosmetic result. METHODS: In this retrospective study, 34 patients underwent surgical treatment for primary PSD; 32 male and 2 female. Patients were suffering from primary PSD, with the cyst located in the gluteal midline...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28228879/zinner-syndrome-diagnosed-by-magnetic-resonance-imaging-and-computed-tomography-role-of-imaging-to-identify-and-evaluate-the-uncommon-variation-in-development-of-the-male-genital-tract
#10
V Fiaschetti, L Greco, V Giuricin, D De Vivo, E Di Caprera, R Di Trapano, F Castellani, R Floris
Seminal vesicle cysts are a very rare condition and its often associated with ipsilateral renal agenesis. The diagnosis of seminal vesicle cysts may be delayed or missed because of the non-specific symptoms of this condition. This article reports a triad of right renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction (Zinner syndrome) in a 56 years old man.
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28228823/recognising-small-image-quality-differences-for-ultrasound-probes-and-the-potential-of-misdiagnosis-due-to-undetected-side-lobes
#11
Georg Doblhoff, Jaroslav Satrapa, Philip Coulthard
BACKGROUND: Ultrasonic imaging is an integral and routine procedure in many medical applications. An increased awareness of the need for quality assurance in this field has led to numerous tests being proposed. Due to the complexity of the problem, the tests directly measuring the important parameters of resolution and contrast of low-echoic structures are not unified, often more qualitative than quantitative, and are performed at large periodic intervals. Uniform sensitivity of an array transducer is a necessary but insufficient requirement for imaging quality of an ultrasound probe...
February 2017: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/28228550/interaction-of-phosphorylated-rab11-fip2-with-eps15-regulates-apical-junction-composition
#12
Lynne A Lapierre, Elizabeth H Manning, Kenya M Mitchell, Cathy M Caldwell, James R Goldenring
MARK2 regulates the establishment of polarity in MDCK cells in part through phosphorylation of serine 227 of Rab11-FIP2. We have now identified Eps15 as an interacting partner of phospho-S227-Rab11-FIP2 (pS227-FIP2). During recovery from low calcium, Eps15 localized to the lateral membrane, prior to pS227-FIP2 arrival. Later in recovery, Eps15 and pS227-FIP2 co-localized at the lateral membrane. In MDCK cells expressing the pseudophosphorylated FIP2 mutant, FIP2(S227E), during recovery from low calcium, Eps15 was trapped and never localized to the lateral membrane...
February 22, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28228430/atypical-case-of-preterm-ovarian-hyperstimulation-syndrome
#13
Michelle A Durst, Brandy Wicklow, Michael Narvey
Preterm ovarian hyperstimulation syndrome is a rare syndrome in which preterm infant girls have hypogastric, upper leg and labial swelling accompanied by elevated serum oestradiol levels and ovarian follicular cysts on ultrasound. Our case is an infant born at 23 weeks gestational age who at 30 weeks postconceptional age (PCA) developed elevated 17-hydroxyprogesterone on her newborn screen with associated clitoromegaly and a ventral groove on the inferior aspect of the erectile tissue. An initial pelvic ultrasound at 32 weeks PCA demonstrated a normal appearing uterus, but the ovaries were not visualised...
February 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28228125/rna-seq-of-life-stages-of-the-oomycete-phytophthora-infestans-reveals-dynamic-changes-in-metabolic-signal-transduction-and-pathogenesis-genes-and-a-major-role-for-calcium-signaling-in-development
#14
Audrey M V Ah-Fong, Kyoung Su Kim, Howard S Judelson
BACKGROUND: The oomycete Phytophthora infestans causes the devastating late blight diseases of potato and tomato. P. infestans uses spores for dissemination and infection, like many other filamentous eukaryotic plant pathogens. The expression of a subset of its genes during spore formation and germination were studied previously, but comprehensive genome-wide data have not been available. RESULTS: RNA-seq was used to profile hyphae, sporangia, sporangia undergoing zoosporogenesis, motile zoospores, and germinated cysts of P...
February 23, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28227414/breast-lesion-detection-and-characterization-with-3d-features
#15
Arathi Sreekumari, K S Shriram, Vivek Vaidya, Arathi Sreekumari, K S Shriram, Vivek Vaidya, Vivek Vaidya, K S Shriram, Arathi Sreekumari
Automated Breast Ultrasound (ABUS) is highly effective as breast cancer screening adjunct technology. Automation can greatly enhance the efficiency of the clinician sifting through the quantum of data in ABUS volumes to spot lesions. We have implemented a fully automatic generic algorithm pipeline for detection and characterization of lesions on such 3D volumes. We compare a wide range of features for region description on their effectiveness at the dual goals of lesion detection and characterization. On multiple feature images, we compute region descriptors at lesion candidate locations obviating the need for explicit lesion segmentation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227204/ultrasound-plane-wave-imaging-with-delay-multiply-and-sum-beamforming-and-coherent-compounding
#16
Giulia Matrone, Alessandro S Savoia, Giosue Caliano, Giovanni Magenes, Giulia Matrone, Alessandro S Savoia, Giosue Caliano, Giovanni Magenes, Giulia Matrone, Giovanni Magenes, Alessandro S Savoia, Giosue Caliano
Improving the frame rate is an important aspect in medical ultrasound imaging, particularly in 3D/4D cardiac applications. However, an accurate trade-off between the higher frame rate and image contrast and resolution should be performed. Plane-Wave Imaging (PWI) can potentially achieve frame rates in the order of 10 kHz, as it uses a single unfocused plane wave (and thus a single transmit event) to acquire the image of the entire region of interest. The lack of transmit focusing however causes a significant drop of image quality, which can be restored by coherently compounding several tilted plane-wave frames, at the expense of the frame rate...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226739/automated-segmentation-of-intra-retinal-cysts-from-optical-coherence-tomography-scans-using-marker-controlled-watershed-transform
#17
G N Girish, Abhishek R Kothari, Jeny Rajan, G N Girish, Abhishek R Kothari, Jeny Rajan, Jeny Rajan, G N Girish, Abhishek R Kothari
Optical Coherence Tomography (OCT) has emerged as a major diagnostic modality for retinal imaging. Although OCT generates gross volumetric data, manual analysis of the images for locating or quantifying retinal cysts is a time consuming process. Recently semi- and fully-automatic methods for locating and segmenting retinal cysts have been proposed in the literature. Our paper proposes a fully automatic method for intra-retinal cyst segmentation using marker controlled watershed transform on B-scan images obtained on OCT scanning...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226379/cutaneous-lymphadenoma-a-trichoblastoma-with-regressive-inflammatory-changes
#18
Sarah Keesecker, Jad Saab, Cynthia M Magro, Vivek Dokania, Anthony P Sclafani
The authors address the entity of cutaneous lymphadenoma. Although considered benign, cutaneous lymphadenoma can be easily misdiagnosed as basal cell carcinoma because of its close clinical and histological resemblance. This entity is rare and controversial both in terms of its histogenesis and the various diagnostic terms assigned to it throughout the literature. While rare, cutaneous lymphadenoma should be considered in the differential of any facial nodule or papule in addition to the more common basal cell carcinoma, nevi, cysts, and appendiceal tumors...
February 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28225971/giant-cell-tumor-of-the-tendon-sheath-a-rare-periungual-location-simulating-myxoid-cyst
#19
Renan Minotto, Camila Britto Rodrigues, Aline Barcellos Grill, Roque Furian
Giant cell tumor of the tendon sheath is a benign soft tissue tumor most frequent between the third and fifth decades of life. It can mimic and make differential diagnoses with several hand tumors. Definitive diagnosis and the treatment of choice are reached with complete resection and histopathological examination. Here we describe a case with clinical presentation similar to that of a myxoid cyst.
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28225802/effect-of-various-nitrogen-conditions-on-population-growth-temporary-cysts-and-cellular-biochemical-compositions-of-karenia-mikimotoi
#20
Yan Zhao, Xuexi Tang, Xiaowei Zhao, You Wang
The harmful algal bloom (HAB)-forming dinoflagellate Karenia mikimotoi was exposed to different nitrogen (N) conditions, in order to study the population growth, temporary cyst production and cellular biochemical compositions in laboratory. The results indicated the population growth of K. mikimotoi was inhibited by different levels of N starvation but showed similar fast recovery after the resupplement of N, and temporary cysts were induced in the period of N starvation. K. mikimotoi grew well in inorganic (NO3-, NO2- and NH4+) and organic (urea) nitrogen sources, but the growth parameters (K, Tp, r) showed differences when simulated by Logistic model regressions...
2017: PloS One
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