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Thoracic pathology

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https://www.readbyqxmd.com/read/29778596/anterior-vs-posterior-approach-for-thoracic-corpectomy-an-analysis-of-risk-factors-outcomes-and-complications
#1
Ryan G Chiu, Jonathan Hobbs, Darian R Esfahani, Saavan Patel, David Rosenberg, Clayton L Rosinski, Akash S Patel, Anisse N Chaker, Ankit I Mehta
BACKGROUND: Thoracic corpectomies are performed for various reasons including spinal deformity, trauma, neoplasms, and infection. Regardless of indication, both anterior and posterior approaches are surgical options, selected based on pathology, anatomy, patient characteristics, and surgical experience. Risk profiles and outcomes for these procedures are poorly characterized, however, and the choice between the two approaches remains inconclusive. OBJECTIVE: To compare risk factors and complications for adult patients undergoing anterior and posterior thoracic corpectomies...
May 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29773295/the-diagnostic-yield-using-ultrasound-guided-needle-aspiration-for-subpleural-primary-lung-cancer-is-not-affected-by-the-radiological-properties-of-the-lesions-resulting-from-computed-tomography
#2
Naoko Iwakami, Shin-Ichiro Iwakami, Munechika Hara, Mitsuaki Sekiya, Takashi Dambara, Kazuhisa Takahashi
BACKGROUND: It is well known that ultrasound-guided needle-aspiration (USGNA) for intrapulmonary subpleural lesion in contact with the pleura is useful and safe, and its diagnostic yield is high. However, reports concerned with the analyses of cases with intrapulmonary subpleural lesion which could not be diagnosed using USGNA are limited. The objective of this study is to clarify the radiological properties of subpleural primary lung cancer which obstruct diagnosis by USGNA. METHODS: The consecutive cases with subpleural primary lung cancer whose radiological properties could be confirmed by thoracic computed tomography (CT) without contrast enhancement (CE), and examined by USGNA at our hospital between January 1999 and December 2014 have been analyzed...
May 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29769481/a-case-of-thoracic-endometriosis-syndrome-presenting-with-recurrent-catamenial-pneumothorax
#3
Shoaib Z Junejo, Sandeep Singh Lubana, Sukhdip Singh Shina, Sandeep Singh Tuli
BACKGROUND Catamenial pneumothorax (CP) is a spontaneous pneumothorax commonly associated with menstrual periods. Endometrial tissues most commonly involve the pelvic region. However, after the pelvis, the lungs are most frequently involved. Thoracic endometriosis should always be suspected in young women presenting with CP. CASE REPORT A 30-year-old woman with history of endometriosis presented with chief complaint of umbilical pain. A computerized tomography (CT) scan of the abdomen and pelvis was performed, which showed an incidental finding of a large right-sided pneumothorax...
May 17, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29764586/-relationship-between-fgfr1-gene-regulation-of-circulating-tumor-cells-and-clinical-features-of-non-small-cell-lung-cancer
#4
Lei Liu, Cheng Huang, Li Li, Naixin Liang, Shanqing Li
BACKGROUND: The methods of detection for recurrence and metastasis in patients with non-small cell lung cancer (NSCLC) have hysteresis and one-sidedness. This study summarizes the relationship between the circulating tumor cell (CTC) in peripheral blood, expression of fibroblast growth factor receptor 1 (FGFR1) and clinic pathological features in 30 patients with NSCLC so as to provide new ideas for the detection of tumor recurrence and metastasis. METHODS: To analyze the clinical data and CTC detection data of 30 cases of NSCLC in Department of Thoracic Surgery, Peking Union Medical College Hospital from November 2016 to June 2017...
May 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/29764516/somatic-mutation-landscape-of-a-meningioma-and-its-pulmonary-metastasis
#5
Yaran Du, Ting Lu, Song Huang, Fangfang Ren, Gang Cui, Jian Chen
BACKGROUND: Extracranial metastasis (ENM) of meningiomas is extremely rare, and typically occurs several years after a primary tumor is diagnosed. However, the genetic changes underlying ENM events have not yet been investigated. CASE PRESENTATION: A 58-year-old male patient was sent to the emergency room of our hospital because of a sudden fall. Magnetic resonance imaging detected a mass at the right frontal sagittal sinus. He underwent tumor resection and recovered well, but post-operative computed tomography revealed three lumps on the right side of his chest...
May 4, 2018: Cancer communications
https://www.readbyqxmd.com/read/29756107/analysis-of-89-patients-who-underwent-tube-thoracostomy-performed-by-general-surgeons
#6
Cihad Tatar, Ahmet Kocakuşak, Bahri Özer, Mehmet Celal Kızılkaya, Tamer Karşıdağ, Aziz Arı, Kenan Büyükaşık
Objective: Death due to thoracic trauma accounts for 20% of all trauma deaths. The aim of this study was to discuss the approach applied by general surgeons to thoracic trauma in our center. Material and Methods: A total of 89 patients (82 male, 7 female; mean age: 26.8 years; range: 7 to 77 years) with thoracic trauma who were admitted to the emergency department and underwent thoracostomy performed by general surgeons between January 2008 and December 2013 were retrospectively analyzed...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29755360/healthy-lung-vessel-morphology-derived-from-thoracic-computed-tomography
#7
Michael Pienn, Caroline Burgard, Christian Payer, Alexander Avian, Martin Urschler, Rudolf Stollberger, Andrea Olschewski, Horst Olschewski, Thorsten Johnson, Felix G Meinel, Zoltán Bálint
Knowledge of the lung vessel morphology in healthy subjects is necessary to improve our understanding about the functional network of the lung and to recognize pathologic deviations beyond the normal inter-subject variation. Established values of normal lung morphology have been derived from necropsy material of only very few subjects. In order to determine morphologic readouts from a large number of healthy subjects, computed tomography pulmonary angiography (CTPA) datasets, negative for pulmonary embolism, and other thoracic pathologies, were analyzed using a fully-automatic, in-house developed artery/vein separation algorithm...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29755099/-the-role-of-video-assisted-thoracic-surgery-in-multimodality-therapy
#8
Yugo Tanaka, Takanori Matsumoto, Yoshimasa Maniwa
Minimally invasive surgery is being widely performed for the management of lung cancers owing to rapid technological advances in surgical devices and techniques. In recent times, because chemotherapy and radiotherapy have both become less invasive treatment strategies, therapeutic opportunities for the use of multimodality therapy have been increasing. Minimally invasive surgery is an important component that requires additional improvements to derive the complete benefit of multimodality therapy. We have been actively performing video-assisted thoracic surgery(VATS) for the management of advanced lung cancers, as well as early lung cancers to reduce surgical stress in our patients, thereby enhancing the scope of multimodality therapy...
April 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29750932/bilateral-posterior-mediastinal-primary-myelolipoma
#9
Ishan Goel, Parul Kaushik, Rama Anand
Myelolipoma(ML) is an uncommon benign mesenchymal tumor consisting of mature adipocytes and hemopoietic elements mostly found in adrenal glands. Bilateral posterior mediastinal primary myelolipoma presents extremely rarely and only 11 such occurrences have been previously described. With no definite symptoms, pathological evaluation is essential for diagnosis. Here the authors present a case of a 63-year old man diagnosed with bilateral posterior mediastinal primary myelolipoma on basis of radiological findings who underwent surgical resection via video-assisted thoracic surgery (VATS)...
May 8, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29750880/akt-enos-and-mapk-signaling-pathways-mediated-the-phenotypic-switching-of-thoracic-aorta-vascular-smooth-muscle-cells-in-aging-hypertensive-rats
#10
Lin Zhang, Zhaoxia Xu, Ying Wu, Jingwen Liao, Fanxing Zeng, Lijun Shi
Considerable evidence demonstrates that phenotypic switching of vascular smooth muscle cells (VSMCs) is influenced by aging and hypertension. During phenotypic switching, VSMCs undergo a switch to a proliferative and migratory phenotype, with this switch being a common pathology in cardiovascular diseases. The aim of this study was to explore the joint influence of age and hypertension on thoracic aortic smooth muscle phenotypic switching and the balance of Akt and mitogen-activated protein kinase (MAPK) signaling during this switch...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29750136/dysfunctional-closed-chest-drainage-common-causative-factors-and-recommendations-for-prevention
#11
Usman Hashmi, Muhammad Nadeem, Abdul Aleem, Fuad Ul Hasan H Khan, Rabeea Gull, Kaleen Ullah, Iftikhar H Khan
Introduction Dysfunctional closed chest drainage unit (CDU) dysfunction is a common but serious clinical problem associated with tube thoracostomy and results in a significant rise in morbidity, prolonged hospital stays, and increased economic burden. This observational study examines the proximate factors of closed CDU dysfunction in addition to their relative frequency. Based on our findings, we suggest logical recommendations for preventing the factors that contribute to closed chest drainage unit dysfunction...
March 9, 2018: Curēus
https://www.readbyqxmd.com/read/29748903/sagittal-classification-in-adolescent-idiopathic-scoliosis-original-description-and-therapeutic-implications
#12
K Abelin-Genevois, D Sassi, S Verdun, P Roussouly
INTRODUCTION: Surgical treatment of AIS aims to correct the coronal and sagittal alignment of the spine. The global alignment of the spine may be normalized through reciprocal changes between the fused spine and adjacent segments. We propose a new classification system describing the specific sagittal patterns induced by AIS to define reproducible guidelines for the surgical strategy. METHODS: We analyzed 100 consecutive AIS patients aged between 12 and 18 years candidate for spinal fusion...
May 10, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29747952/awake-thoracic-endovascular-aneurysm-repair-for-aortic-rupture-a-case-series
#13
Jessica Forcillo, Yazan M Duwayri, William D Jordan, Bradley G Leshnower
Thoracic endovascular aortic repair (TEVAR) has been proven to be the optimal therapy for patients with a ruptured descending thoracic aortic pathology. In these emergent settings, TEVAR provides a rapid delivery of treatment to an unstable patient with a lethal disease. Typically, the greatest challenge is maintaining hemodynamic stability until the time of graft deployment. In this report, we describe our technique of performing awake TEVAR for ruptured descending thoracic aortic disease.
April 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29745733/anterior-cervical-approach-for-the-treatment-of-axial-or-high-thoracic-levels
#14
Ran Harel, Maya Nulman, Zvi R Cohen, Nachshon Knoller
PURPOSE: Application of the anterior sub-axial cervical approach to the axial spine or the high thoracic spine has been previously described. Evaluation methods to determine the feasibility of these approaches were also described but alternative method was utilized in the current study. We describe our experience expanding the boundaries of anterior cervical approach utilizing a novel algorithm for approach selection. MATERIALS AND METHODS: A retrospective analysis of patients' files and imaging data of all anterior cervical approach to treat pathologies above C2-3 disc space or below C7-D1 disc space...
May 10, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29742312/semi-quantitative-methods-yield-greater-inter-and-intraobserver-agreement-than-subjective-methods-for-interpreting-99m-technetium-hydroxymethylene-diphosphonate-uptake-in-equine-thoracic-processi-spinosi
#15
Claudia van Zadelhoff, Anna Ehrle, Roswitha Merle, Werner Jahn, Christoph Lischer
Scintigraphy is a standard diagnostic method for evaluating horses with back pain due to suspected thoracic processus spinosus pathology. Lesion detection is based on subjective or semi-quantitative assessments of increased uptake. This retrospective, analytical study is aimed to compare semi-quantitative and subjective methods in the evaluation of scintigraphic images of the processi spinosi in the equine thoracic spine. Scintigraphic images of 20 Warmblood horses, presented for assessment of orthopedic conditions between 2014 and 2016, were included in the study...
May 9, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29742176/proportion-and-clinical-characteristics-of-non-asthmatic-non-smokers-among-adults-with-airflow-obstruction
#16
Hiroto Takiguchi, Tomoe Takeuchi, Kyoko Niimi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Tsuyoshi Oguma, Takuya Aoki, Tetsuya Urano, Satomi Asai, Hayato Miyachi, Koichiro Asano
BACKGROUND AND OBJECTIVES: Chronic obstructive pulmonary disease (COPD) mainly develops after long-term exposure to cigarette or biomass fuel smoke, but also occurs in non-smokers with or without a history of asthma. We investigated the proportion and clinical characteristics of non-smokers among middle-aged to elderly subjects with airflow obstruction. METHODS: We retrospectively analyzed 1,892 subjects aged 40-89 years who underwent routine preoperative spirometry at a tertiary university hospital in Japan...
2018: PloS One
https://www.readbyqxmd.com/read/29742150/efficacy-of-parenteral-vaccination-against-tuberculosis-with-heat-inactivated-mycobacterium-bovis-in-experimentally-challenged-goats
#17
Claudia Arrieta-Villegas, Tania Perálvarez, Enric Vidal, Zoë Puighibet, Xavier Moll, Albert Canturri, Iker A Sevilla, Yvonne Espada, Ramón A Juste, Mariano Domingo, Bernat Pérez de Val
Tuberculosis (TB) in animals is a re-emerging disease with a wide range of hosts that causes large economic losses in livestock. Goats are particularly susceptible to TB and, in endemic areas, vaccination may be a valuable measure to control the disease. The main aim of this study was to evaluate the efficacy of parenteral vaccination of goats with a heat-inactivated Mycobacterium bovis (HIMB) vaccine, and compare it to M. bovis Bacille Calmette-Guérin (BCG) vaccine. Twenty-four goat kids were divided in 3 groups as following: HIMB vaccinated group (n = 8), BCG vaccinated group (n = 8) and unvaccinated group (n = 8)...
2018: PloS One
https://www.readbyqxmd.com/read/29735032/composite-and-multivisceral-transplantation-nomenclature-surgical-techniques-current-practice-and-long-term-outcome
#18
REVIEW
Guilherme Costa, Neha Parekh, Mohammed Osman, Sherif Armanyous, Masato Fujiki, Kareem Abu-Elmagd
The successful development of multivisceral and composite visceral transplantation is among the milestones in the recent history of human organ transplantation. All types of gastrointestinal transplantation have evolved to be the standard of care for patients with gut failure and complex abdominal pathologic conditions. The outcome has markedly improved over the last 3 decades owing to technical innovation, novel immunosuppression, and better postoperative care. Recent data documented significant improvement in the long-term therapeutic indices of all types of visceral transplantation close to that achieved with thoracic and solid abdominal organs...
June 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29733012/robotic-approach-in-benign-and-malignant-esophageal-tumors-a-preliminary-seven-case-series
#19
Victor Tomulescu, Codrut Stanescu, Cristian Blajut, Loredana Barbulescu, Gabriela Droc, Vlad Herlea, Irinel Popescu
Esophageal surgery has been recognized as very challenging for surgeons and risky for patients. Thoracoscopic approach have proved its benefit in esophageal surgery but has some drawbacks as tremor and limited degrees of freedom, contra-intuitive movements and fulcrum effect of the surgical tools. Robotic technology has been developed with the intent to overcome these limitations of the standard laparoscopy or thoracoscopy. These benefits of robotic procedure are most advantageous when operating in remote areas difficult to reach as in esophageal surgery...
March 2018: Chirurgia
https://www.readbyqxmd.com/read/29732192/electromagnetic-navigation-bronchoscopy-chungnam-national-university-hospital-experience
#20
Hyun Jin Cho, Md Roknuggaman, Woo Sik Han, Shin Kwang Kang, Min-Woong Kang
Background: To find small pulmonary nodules or ground grass nodules (GGNs) with video-assisted thoracoscopic surgery (VATS) is very difficult. There are several conventional methods to localize small nodules or GGNs, which require additional radiation exposure and may cause some complications such as pneumothorax or hemothorax. We aimed to evaluate the effectiveness and feasibility of electromagnetic navigational bronchoscopy-guided pulmonary localization in a minimally invasive thoracic surgery field...
April 2018: Journal of Thoracic Disease
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