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Elastography and radiotherapy

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https://www.readbyqxmd.com/read/27461395/a-longitudinal-magnetic-resonance-elastography-study-of-murine-brain-tumors-following-radiation-therapy
#1
Y Feng, E H Clayton, R J Okamoto, J Engelbach, P V Bayly, J R Garbow
An accurate and noninvasive method for assessing treatment response following radiotherapy is needed for both treatment monitoring and planning. Measurement of solid tumor volume alone is not sufficient for reliable early detection of therapeutic response, since changes in physiological and/or biomechanical properties can precede tumor volume change following therapy. In this study, we use magnetic resonance elastography to evaluate the treatment effect after radiotherapy in a murine brain tumor model. Shear modulus was calculated and compared between the delineated tumor region of interest (ROI) and its contralateral, mirrored counterpart...
August 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27169866/lipotransfer-for-radiation-induced-skin-fibrosis
#2
REVIEW
R Kumar, M Griffin, G Adigbli, N Kalavrezos, P E M Butler
BACKGROUND: Radiation-induced fibrosis (RIF) is a late complication of radiotherapy that results in progressive functional and cosmetic impairment. Autologous fat has emerged as an option for soft tissue reconstruction. There are also sporadic reports suggesting regression of fibrosis following regional lipotransfer. This systematic review aimed to identify cellular mechanisms driving RIF, and the potential role of lipotransfer in attenuating these processes. METHODS: PubMed, OVID and Google Scholar databases were searched to identify all original articles regarding lipotransfer for RIF...
July 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27147361/technical-note-multipurpose-ct-ultrasound-and-mri-breast-phantom-for-use-in-radiotherapy-and-minimally-invasive-interventions
#3
Mark Ruschin, Sean R H Davidson, William Phounsy, Tae Sun Yoo, Lee Chin, Jean-Philippe Pignol, Ananth Ravi, Claire McCann
PURPOSE: To develop a multipurpose gel-based breast phantom consisting of a simulated tumor with realistic imaging properties in CT, ultrasound and MRI, or a postsurgical cavity on CT. Applications for the phantom include: deformable image registration (DIR) quality assurance (QA), autosegmentation validation, and localization testing and training for minimally invasive image-guided procedures such as those involving catheter or needle insertion. METHODS: A thermoplastic mask of a typical breast patient lying supine was generated and then filled to make an array of phantoms...
May 2016: Medical Physics
https://www.readbyqxmd.com/read/27002558/review-of-ultrasound-image-guidance-in-external-beam-radiotherapy-part-ii-intra-fraction-motion-management-and-novel-applications
#4
Tuathan O'Shea, Jeffrey Bamber, Davide Fontanarosa, Skadi van der Meer, Frank Verhaegen, Emma Harris
Imaging has become an essential tool in modern radiotherapy (RT), being used to plan dose delivery prior to treatment and verify target position before and during treatment. Ultrasound (US) imaging is cost-effective in providing excellent contrast at high resolution for depicting soft tissue targets apart from those shielded by the lungs or cranium. As a result, it is increasingly used in RT setup verification for the measurement of inter-fraction motion, the subject of Part I of this review (Fontanarosa et al 2015 Phys...
April 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/26936715/systematic-feasibility-analysis-of-a-quantitative-elasticity-estimation-for-breast-anatomy-using-supine-prone-patient-postures
#5
Katelyn Hasse, John Neylon, Ke Sheng, Anand P Santhanam
PURPOSE: Breast elastography is a critical tool for improving the targeted radiotherapy treatment of breast tumors. Current breast radiotherapy imaging protocols only involve prone and supine CT scans. There is a lack of knowledge on the quantitative accuracy with which breast elasticity can be systematically measured using only prone and supine CT datasets. The purpose of this paper is to describe a quantitative elasticity estimation technique for breast anatomy using only these supine/prone patient postures...
March 2016: Medical Physics
https://www.readbyqxmd.com/read/26855535/advances-in-endoscopic-ultrasound-imaging-of-colorectal-diseases
#6
REVIEW
Elena Tatiana Cârțână, Dan Ionuț Gheonea, Adrian Săftoiu
The development of endoscopic ultrasound (EUS) has had a significant impact for patients with digestive diseases, enabling enhanced diagnostic and therapeutic procedures, with most of the available evidence focusing on upper gastrointestinal (GI) and pancreatico-biliary diseases. For the lower GI tract the main application of EUS has been in staging rectal cancer, as a complementary technique to other cross-sectional imaging methods. EUS can provide highly accurate in-depth assessments of tumour infiltration, performing best in the diagnosis of early rectal tumours...
February 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26343078/acoustic-radiation-force-impulse-quantitative-elastography-a-new-noninvasive-technique-for-the-evaluation-of-parotid-glands-a-preliminary-study-in-controls-and-in-patients-with-irradiated-nasopharyngeal-carcinoma
#7
Iulia Badea, Attila Tamas-Szora, Ioana Chiorean, Maria Crisan, Elisabeta Ciuleanu, Grigore Baciut, Mindra Badea
AIM: We aim to define the values of the shear wave velocity (SWV) in the normal parotid glands (PG) and to identify the modifications of tissue stiffness in patients with irradiated nasopharyngeal carcinoma. MATERIAL AND METHODS: Sixty normal parotid glands pertaining to 30 healthy volunteers and 40 pathological parotid glands pertaining to 20 patients who had had underwent radiation therapy for nasopharyngeal carcinoma were included in this study. The patients underwent a B mode ultrasonography examination and the volume of the parotid gland was determined...
September 2015: Medical Ultrasonography
https://www.readbyqxmd.com/read/25831151/primary-non-hodgkin-lymphoma-of-the-breast-ultrasonography-elastography-digital-mammography-contrast-enhanced-digital-mammography-and-pathology-findings
#8
Christina An Gkali, Athanasios N Chalazonitis, Eleni Feida, Aris Giannos, Maria Sotiropoulou, Constantine Dimitrakakis, Dimitrios Loutradis
Lymphomas constitute approximately 0.15% of malignant mammary neoplasms. Less than 0.5% of all malignant lymphomas involve the breast primarily. Primary non-Hodgkin breast lymphoma is usually right sided. The combined therapy approach, with chemotherapy and radiotherapy, is the most successful treatment. Mastectomy offers no benefit in the treatment of primary non-Hodgkin breast lymphoma. To the author's knowledge, this is the first published case of primary non-Hodgkin breast lymphoma reported with conventional ultrasonography, elastography (both freehand and acoustic radiation force impulse imaging), digital mammography, contrast-enhanced digital mammography, and pathology findings...
December 2015: Ultrasound Quarterly
https://www.readbyqxmd.com/read/25581411/focal-nodular-hyperplasia-of-the-liver-an-emerging-complication-of-hematopoietic-sct-in-children
#9
M Pillon, N S Carucci, C Mainardi, E Carraro, M Zuliani, L Chemello, E Calore, M Tumino, S Varotto, T Toffolutti, R Destro, M V Gazzola, R Alaggio, G Basso, C Messina
Hepatic focal nodular hyperplasia (FNH) is a nonmalignant condition rarely affecting children previously treated for cancer, especially those who received hematopoietic SCT (HSCT). Some aspects of its pathogenesis still remain unclear and a strong association with specific risk factors has not yet been identified. We report here a single institution's case series of 17 patients who underwent HSCT and were diagnosed with FNH, analyzing retrospectively their clinical features and the radiological appearance of their hepatic lesions...
March 2015: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/25232461/role-of-endoscopic-ultrasound-in-the-diagnosis-of-pancreatic-cancer
#10
REVIEW
Juana Gonzalo-Marin, Juan Jose Vila, Manuel Perez-Miranda
Endoscopic ultrasonography (EUS) with or without fine needle aspiration has become the main technique for evaluating pancreatobiliary disorders and has proved to have a higher diagnostic yield than positron emission tomography, computed tomography (CT) and transabdominal ultrasound for recognising early pancreatic tumors. As a diagnostic modality for pancreatic cancer, EUS has proved rates higher than 90%, especially for lesions less than 2-3 cm in size in which it reaches a sensitivity rate of 99% vs 55% for CT...
September 15, 2014: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/25202703/shear-wave-elastography-a-new-noninvasive-tool-to-assess-the-intensity-of-fibrosis-of-irradiated-salivary-glands-in-head-and-neck-cancer-patients
#11
Jarosław Kałużny, Tomasz Kopeć, Ewelina Szczepanek-Parulska, Adam Stangierski, Edyta Gurgul, Marek Ruchała, Piotr Milecki, Małgorzata Wierzbicka
The aim of the study was to assess salivary gland parenchyma by means of sonoelastography in patients irradiated for head and neck squamous cell carcinoma (HNSCC). The studied group consisted of 52 patients after radiotherapy (RT) and 54 healthy volunteers. All of the former were treated for advanced larynx (40), oropharynx (9), or maxilla (3) squamous cancers and suffered from chronic dryness. Ultrasonography (US) and elastography (ES) were performed, as well as an assessment of the amount of saliva and Common Terminology Criteria for Adverse Events (CTCAE) scale...
2014: BioMed Research International
https://www.readbyqxmd.com/read/25176033/combined-endorectal-ultrasonography-and-strain-elastography-for-the-staging-of-early-rectal-cancer
#12
J E R Waage, S P Bach, F Pfeffer, S Leh, R F Havre, S Ødegaard, G Baatrup
AIM: Strain elastography is a novel approach to rectal tumour evaluation. The primary aim of this study was to correlate elastography to pT stages of rectal tumours and to assess the ability of the method to differentiate rectal adenomas (pT0) from early rectal cancer (pT1-2). Secondary aims were to compare elastography with endorectal ultrasonography (ERUS) and to propose a combined strain elastography and ERUS staging algorithm. METHOD: In all, 120 consecutive patients with a suspected rectal tumour were examined in this staging study...
January 2015: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/25171602/shear-wave-elastography-a-new-quantitative-assessment-of-post-irradiation-neck-fibrosis
#13
K H Liu, K Bhatia, W Chu, L T He, S F Leung, A T Ahuja
PURPOSE: Shear wave elastography (SWE) is a new technique which provides quantitative assessment of soft tissue stiffness. The aim of this study was to assess the reliability of SWE stiffness measurements and its usefulness in evaluating post-irradiation neck fibrosis. MATERIALS AND METHODS: 50 subjects (25 patients with previous radiotherapy to the neck and 25 sex and age-matched controls) were recruited for comparison of SWE stiffness measurements (Aixplorer, Supersonic Imagine)...
August 2015: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/24942263/long-term-cerebral-and-vascular-complications-after-irradiation-of-the-neck-in-head-and-neck-cancer-patients-a-prospective-cohort-study-study-rationale-and-protocol
#14
Joyce Wilbers, Arnoud C Kappelle, Roy Pc Kessels, Stefan Ca Steens, Frederick Ja Meijer, Johannes H Kaanders, Roy Am Haast, Laura E Versteeg, Anil M Tuladhar, Chris L de Korte, Hendrik Hg Hansen, Frank J Hoebers, Willem Boogerd, Erik D van Werkhoven, Marlies E Nowee, Guus Hart, Harry Bartelink, Lucille D Dorresteijn, Ewoud J van Dijk
BACKGROUND: Successful treatment options for cancer result in more young long-term survivors prone for long-term complications. Carotid artery vasculopathy is a potential long-term complication after radiotherapy of the neck, resulting in cerebrovascular events and probably deficits in cognitive and motor functioning. Better insight into the underlying pathofysiology of radiotherapy induced carotid artery vasculopathy is needed for prognostic purposes and to develop preventive strategies...
2014: BMC Neurology
https://www.readbyqxmd.com/read/23412910/ultrasound-elastography-as-an-objective-diagnostic-measurement-tool-for-lymphoedema-of-the-treated-breast-in-breast-cancer-patients-following-breast-conserving-surgery-and-radiotherapy
#15
Nele Adriaenssens, Dries Belsack, Ronald Buyl, Leonardo Ruggiero, Catherine Breucq, Johan De Mey, Pierre Lievens, Jan Lamote
BACKGROUND.: Lymphoedema of the operated and irradiated breast is a common complication following early breast cancer treatment. There is no consensus on objective diagnostic criteria and standard measurement tools. This study investigates the use of ultrasound elastography as an objective quantitative measurement tool for the diagnosis of parenchymal breast oedema. PATIENTS AND METHODS.: The elasticity ratio of the subcutis, measured with ultrasound elastography, was compared with high-frequency ultrasound parameters and subjective symptoms in twenty patients, bilaterally, prior to and following breast conserving surgery and breast irradiation...
December 2012: Radiology and Oncology
https://www.readbyqxmd.com/read/20426026/tracked-regularized-ultrasound-elastography-for-targeting-breast-radiotherapy
#16
Hassan Rivaz, Pezhman Foroughi, Ioana Fleming, Richard Zellars, Emad Boctor, Gregory Hager
Tracked ultrasound elastography can be used for guidance in partial breast radiotherapy by visualizing the hard scar tissue around the lumpectomy cavity. For clinical success, the elastography method needs to be robust to the sources of decorrelation between ultrasound images, specifically fluid motions inside the cavity, change of the appearance of speckles caused by compression or physiologic motions, and out-of-plane motion of the probe. In this paper, we present a novel elastography technique that is based on analytic minimization of a regularized cost function...
2009: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/19945211/quantitative-ultrasonic-elastography-for-gel-dosimetry
#17
Remo A Crescenti, Jeffrey C Bamber, Assad A Oberai, Paul E Barbone, Joseph P Richter, Carlos Rivas, Nigel L Bush, Steve Webb
Advanced radiation techniques such as intensity-modulated radiotherapy (IMRT) for complex geometries in which targets are close to organs at risk have been introduced in radiation therapy, creating a need for procedures that allow easy three-dimensional (3-D) measurement of dose for verification purposes. Polymer gels that change their material properties when irradiated have been suggested for such use. For example, the change in their magnetic properties has been thoroughly investigated with magnetic resonance imaging (MRI)...
February 2010: Ultrasound in Medicine & Biology
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