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https://www.readbyqxmd.com/read/29679695/serial-nse-measurement-identifies-non-survivors-following-out-of-hospital-cardiac-arrest
#1
Kieran Gillick, Kieron Rooney
AIMS: Prognostication following out-of-hospital cardiac arrest (OHCA) remains challenging. A multimodal approach is favoured, including consideration of the biomarker neuron-specific enolase (NSE) (Sandroni et al., 2014). Our objective was to investigate the utility of serial NSE measurements and to determine an appropriate cut-off value for prediction of death before hospital discharge using data from our tertiary care centre. METHODS: Retrospective analysis of patients admitted to the critical care unit of a tertiary centre critical care unit in the UK following an out-of-hospital cardiac arrest...
April 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29679639/decoding-fibrosis-mechanisms-and-translational-aspects
#2
Liliana Schaefer
Fibrosis, a complex process of abnormal tissue healing which inevitably leads to loss of physiological organ structure and function, is a world-wide leading cause of death. Despite a large body of research over the last two decades, antifibrotic approaches are mainly limited to organ replacement therapy generating high costs of medical care. In this translational issue, a unique group of basic and clinical researchers provide meaningful answers to a desperate call of society for effective antifibrotic treatments...
April 18, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29679531/the-association-of-early-postoperative-lactate-levels-with-morbidity-after-elective-major-abdominal-surgery
#3
Jelena Veličković, Ivan Palibrk, Biljana Miličić, Dejan Veličković, Bojan Jovanović, Goran Rakić, Milorad Petrović, Vesna Bumbaširević
Lactate levels are widely used as an indicator of outcome in critically ill patients. We investigated the prognostic value of postoperative lactate levels for postoperative complications (POC), mortality and length of hospital stay after elective major abdominal surgery. A total of 195 patients were prospectively evaluated. Lactate levels were assessed on admission to the intensive care unit (ICU) [L0], 4 hours (L4), 12 hours (L12), and 24 hours (L24) after the operation. Demographic and perioperative clinical data were collected...
April 21, 2018: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29679387/the-pharmacokinetics-and-pharmacodynamics-of-carfentanil-after-recreational-exposure-a-case-report
#4
Uvaraj Uddayasankar, Colin Lee, Curtis Oleschuk, Gregg Eschun, Robert E Ariano
Carfentanil and related fentanyl analogues have been linked to a number of overdose deaths from drug users in several cities across North America. Diagnosis of carfentanil exposure requires a very high index of clinical suspicion, especially because available laboratory narcotic screens do not detect this agent. We describe a 34-year-old male admitted with depressed level of consciousness and in respiratory failure after recreational exposure to a white powder later inferred to contain carfentanil. Urine and whole blood samples were obtained for conventional preliminary drug screen immunoassays for unknown exposures; in addition to utilizing high pressure liquid chromatography tandem mass spectrometry assay for quantification of carfentanil and its metabolite...
April 20, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29679189/an-exploratory-study-of-spirituality-and-spiritual-care-among-malaysian-nurses
#5
Mohd Arif Atarhim, Susan Lee, Beverley Copnell
The increasing evidence that spirituality is a critical component for promoting health and well-being has made spirituality more significant to nursing practice. However, although nurses' perceptions of spirituality have been studied in western countries, there has been little research on this topic in Southeast Asian countries where religions other than Christianity predominate. This study explores Malaysian nurses' perceptions of spirituality and spiritual care and examines associations between socio-demographics and their perceptions...
April 20, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29679169/the-utility-of-scrotal-ultrasonography-in-the-emergent-setting-beyond-epididymitis-versus-torsion
#6
Christopher R McAdams, Andrew J Del Gaizo
Scrotal pain is a common acute presentation for medical care. Testicular torsion and epididymo-orchitis are two diagnoses for which early detection is critical and their sonographic imaging features have been thoroughly described in the radiologic literature. Other important conditions for which radiologists must be aware have received less attention. This article will highlight key traumatic and non-traumatic causes of acute scrotal pain other than testicular torsion and epididymo-orchitis that may present in the emergency department setting...
April 21, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29679132/-self-reported-vision-in-gerontological-health-services-research-and-practice-an-opening-plea
#7
REVIEW
J Köberlein-Neu, A Seifert, I Himmelsbach
The use of self-reported vision is an integral part of most population surveys and is primarily used for healthcare monitoring. Since the patient's assessment is not always consistent with the objectively measured clinical parameters, the majority of the literature looks critically at the adequacy of self-reported vision, particularly with respect to answering epidemiological questions; however, it is often misunderstood that self-reported vision measures far more than the directly derived information show...
April 20, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29679089/general-practitioner-s-attitudes-and-confidence-in-managing-patients-with-dementia-in-singapore
#8
Mythily Subramaniam, Hui Lin Ong, Edimansyah Abdin, Boon Yiang Chua, Saleha Shafie, Fiona Devi Siva Kumar, Sophia Foo, Li Ling Ng, Alvin Lum, Janhavi A Vaingankar, Siow Ann Chong
The number of people living with dementia is increasing globally as a result of an ageing population. General practitioners (GPs), as the front-line care providers in communities, are important stakeholders in the system of care for people with dementia. This commentary describes a study conducted to understand GPs' attitudes and self-perceived competencies when dealing with patients with dementia and their caregivers in Singapore. A set of study information sheet and survey questionnaires were mailed to selected GP clinics in Singapore...
March 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29678866/gaps-in-guidelines-for-the-management-of-diabetes-in-low-and-middle-income-versus-high-income-countries-a-systematic-review
#9
REVIEW
Mayowa O Owolabi, Joseph O Yaria, Meena Daivadanam, Akintomiwa I Makanjuola, Gary Parker, Brian Oldenburg, Rajesh Vedanthan, Shane Norris, Ayodele R Oguntoye, Morenike A Osundina, Omarys Herasme, Sulaiman Lakoh, Luqman O Ogunjimi, Sarah E Abraham, Paul Olowoyo, Carolyn Jenkins, Wuwei Feng, Hernán Bayona, Sailesh Mohan, Rohina Joshi, Ruth Webster, Andre P Kengne, Antigona Trofor, Lucia Maria Lotrean, Devarsetty Praveen, Jessica H Zafra-Tanaka, Maria Lazo-Porras, Kirsten Bobrow, Michaela A Riddell, Konstantinos Makrilakis, Yannis Manios, Bruce Ovbiagele
OBJECTIVE: The extent to which diabetes (DM) practice guidelines, often based on evidence from high-income countries (HIC), can be implemented to improve outcomes in low- and middle-income countries (LMIC) is a critical challenge. We carried out a systematic review to compare type 2 DM guidelines in individual LMIC versus HIC over the past decade to identify aspects that could be improved to facilitate implementation. RESEARCH DESIGN AND METHODS: Eligible guidelines were sought from online databases and websites of diabetes associations and ministries of health...
May 2018: Diabetes Care
https://www.readbyqxmd.com/read/29678798/analysis-of-college-students-personal-health-information-activities-online-survey
#10
Sujin Kim, Donghee Sinn, Sue Yeon Syn
BACKGROUND: With abundant personal health information at hand, individuals are faced with a critical challenge in evaluating the informational value of health care records to keep useful information and discard that which is determined useless. Young, healthy college students who were previously dependents of adult parents or caregivers are less likely to be concerned with disease management. Personal health information management (PHIM) is a special case of personal information management (PIM) that is associated with multiple interactions among varying stakeholders and systems...
April 20, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29678531/-restructuring-of-medical-specialist-treatment-using-the-example-of-ambulatory-special-medical-care-asv-taking-a-critical-look-at-its-aims-and-implementation
#11
REVIEW
Robert Dengler, Manfred Cassens
With the GKV-VStG act in 2012, the former section 116b SGB V was transformed into ambulatory special medical care (ASV). This system comprises the diagnosis and therapy of rare or complex diseases which are difficult to treat, in need of a special qualification of doctors, an interdisciplinary cooperation and/or special facilities. For the first time, a uniform regulatory framework was established for the participation of office- as well as hospital-based doctors in ambulatory care. There is no planning of demand or licensed permission...
April 18, 2018: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29678473/female-sexual-dysfunction-among-muslim-women-increasing-awareness-to-improve-overall-evaluation-and-treatment
#12
REVIEW
Sameena Rahman
INTRODUCTION: Muslim women are an increasingly underserved population in the United States and worldwide. Diagnosis and treatment of female sexual dysfunction bring unique challenges because of the conservative nature of those practicing the religion. Several cultural and religious codes of conduct affect sexual behavior and the dysfunction that can ensue. AIM: To assess and describe the types of sexual dysfunction that have been found in Muslim women internationally and encourage a better understanding of their issues to enhance health care delivery...
April 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29678439/prevalence-and-associated-factors-with-voice-disorders-in-brazilian-community-dwelling-older-adults
#13
Amanda C B Góis, Leandro Pernambuco, Kenio Costa de Lima
OBJECTIVES: This study aimed to estimate the prevalence and factors associated with voice disorders (VDs) in Brazilian community-dwelling older adults. STUDY DESIGN: This is a cross-sectional study. METHODS: The sample comprised 463 older adults (60 years or more) of both sexes living in a Brazilian northeastern city. Variables were related to socioeconomic and demographic profile, lifestyle, and general health conditions, in addition to the validated "Screening for Voice Disorders in Older Adults" (RAVI) questionnaire...
April 17, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29678361/chikungunya-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#14
Pravin Amin, Gisele Sampaio Silva, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Dilip R Karnad, Guy A Richards
Chikungunya is an arbovirus that is transmitted by the Aedes mosquito causing a febrile illness with periodic outbreaks in large parts of the world. In the last decade it has become a public health concern in a host of countries and has affected international tourists. In the vast majority of cases Chikungunya presents as an acute febrile illness, associated with rash, headache, myalgia and debilitating arthralgia or even polyarthritis. A small proportion of patients present atypically with nervous, ocular, renal, myocardial, respiratory and renal system involvement and may require ICU management...
April 7, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29678304/improving-postoperative-neonatal-nutritional-practices-in-an-intensive-care-unit-using-the-pdsa-cycle
#15
Jennifer Newcombe, Eileen Fry-Bowers
Quality Improvement models offer a framework for health care professionals to follow in implementing process improvement changes. Use of these models promotes a systematic approach to problem solving, keeps providers from eliminating important steps, facilitates team work, and provides a clear plan for ongoing communication. This paper describes use of the Plan-Do-Study-Act model to implement a unit-based quality improvement project that focused on improving postoperative nutritional practices for neonates with critical congenital heart disease following complex cardiac surgery...
April 17, 2018: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/29678121/the-relationship-between-adverse-neighborhood-socioeconomic-context-and-hiv-continuum-of-care-outcomes-in-a-diverse-hiv-clinic-cohort-in-the-southern-united-states
#16
Peter F Rebeiro, Chanelle J Howe, William B Rogers, Sally S Bebawy, Megan Turner, Asghar Kheshti, Catherine C McGowan, Stephen P Raffanti, Timothy R Sterling
Retention in care and viral suppression are critical to delaying HIV progression and reducing transmission. Neighborhood socioeconomic context (NSEC) may affect HIV care receipt. We therefore assessed NSEC's impact on retention and viral suppression in a diverse HIV clinical cohort. HIV-positive adults with ≥1 visit at the Vanderbilt Comprehensive Care Clinic and 5-digit ZIP code tabulation area (ZCTA) information between 2008 and 2012 contributed. NSEC z-score indices used neighborhood-level socioeconomic indicators for poverty, education, labor-force participation, proportion of males, median age, and proportion of residents of black race by ZCTA...
April 20, 2018: AIDS Care
https://www.readbyqxmd.com/read/29678088/translating-ehealth-visions-from-strategy-to-practice-a-benefit-management-approach
#17
Sidsel Villumsen, Christian Nøhr, Arild Faxvaag
The municipalities and the Regional Health Authorities in Central Norway have been assigned a mandate to implement a shared electronic health record, Helseplattformen, reflecting the visions set out in the national eHealth white paper 'One Citizen - One Record'. This study identifies and describe anticipated benefit streams of clinical decision support in 'One Citizen - One Record' and the user requirement specification documents of Helseplattformen. This study found that the benefit stream of clinical decision support translates from the health policy visions stated in 'One Citizen - One Record' into Helseplattformen...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29678030/medical-system-choice-information-that-affects-the-selection-of-healthcare-provider-in-australia
#18
Tony Sahama, Andrew Stranieri, Kerryn Butler-Henderson, Isaac Golden
Many complementary and alternative medical practices (CAM) are readily assessable in Australia alongside Allopathic practitioners. Although CAM practices are prevalent, little is known about how patients seek and use information when deciding which system to consult. We report some preliminary findings of a longitudinal study, designed to solicit factors that influence the Australian public when selecting from diverse medical systems. Fifty-four general public participants, willing to provide their confidential and anonymous opinion were included...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677975/minimal-important-difference-in-outcome-of-disc-degenerative-disease-treatment-the-patients-perspective
#19
Linda Greta Dui, Federico Cabitza, Pedro Berjano
Evaluation of treatments effectiveness in a context of value-based health care is based on outcomes, and in their assessment. The patient perspective is gaining renovated interest, as demonstrated by the increasing diffusion of Patient Reported Outcome Measure (PROMs) collection initiatives. The concept of Minimal Clinically Important Dif-ference (MID) is generally seen as the basis to estimate the actual effect perceived by the patient after a treatment, like a surgical intervention, but a universally recognized threshold has not yet been established...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677941/automated-differentiation-of-incident-and-prevalent-cases-in-primary-care-computerised-medical-records-cmr
#20
Nadia Smith, Valerie Livina, Rachel Byford, Filipa Ferreira, Ivelina Yonova, Simon de Lusignan
Identifying incident (first or new) episodes of illness is critical in sentinel networks to inform about the seasonal onset of diseases and to give early warning of epidemics, as well as differentiating change in health service utilization from change in pattern of disease. The most reliable way of differentiating incident from prevalent cases is through the clinician assigning episode type to the patient's computerized medical record (CMR). However, episode type assignment is often made inconsistently. The objective of this collaborative study between the Royal College of General Practitioners Research and Surveillance Centre (RCGP RSC), University of Surrey and the National Physical Laboratory (NPL) is to develop a methodology to reconstruct missing or miscoded episode types...
2018: Studies in Health Technology and Informatics
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