keyword
MENU ▼
Read by QxMD icon Read
search

suicide burden

keyword
https://www.readbyqxmd.com/read/27919695/metabolomics-identifies-perturbations-in-amino-acid-metabolism-in-the-prefrontal-cortex-of-the-learned-helplessness-rat-model-of-depression
#1
Xinyu Zhou, Lanxiang Liu, Yuqing Zhang, Juncai Pu, Lining Yang, Chanjuan Zhou, Shuai Yuan, Hanping Zhang, Peng Xie
Major depressive disorder is a serious psychiatric condition associated with high rates of suicide and is a leading cause of health burden worldwide. However, the underlying molecular mechanisms of major depression are still essentially unclear. In our study, a non-targeted gas chromatography-mass spectrometry-based metabolomics approach was used to investigate metabolic changes in the prefrontal cortex of the learned helplessness rat model of depression. Body-weight measurements and behavioral tests including the active escape test, sucrose preference test, forced swimming test, elevated plus-maze and open field test were used to assess changes in the behavioral spectrum after inescapable footshock stress...
December 2, 2016: Neuroscience
https://www.readbyqxmd.com/read/27888514/the-burden-of-premature-mortality-of-epilepsy-in-high-income-countries-a-systematic-review-from-the-mortality-task-force-of-the-international-league-against-epilepsy
#2
REVIEW
David J Thurman, Giancarlo Logroscino, Ettore Beghi, W Allen Hauser, Dale C Hesdorffer, Charles R Newton, Fulvio Alexandre Scorza, Josemir W Sander, Torbjörn Tomson
Since previous reviews of epidemiologic studies of premature mortality among people with epilepsy were completed several years ago, a large body of new evidence about this subject has been published. We aim to update prior reviews of mortality in epilepsy and to reevaluate and quantify the risks, potential risk factors, and causes of these deaths. We systematically searched the Medline and Embase databases to identify published reports describing mortality risks in cohorts and populations of people with epilepsy...
November 26, 2016: Epilepsia
https://www.readbyqxmd.com/read/27883222/alcohol-misuse-and-co-occurring-mental-disorders-among-new-soldiers-in-the-u-s-army
#3
Murray B Stein, Laura Campbell-Sills, Joel Gelernter, Feng He, Steven G Heeringa, Matthew K Nock, Nancy A Sampson, Xiaoying Sun, Sonia Jain, Ronald C Kessler, Robert J Ursano
BACKGROUND: Problem drinking that predates enlistment into military service may contribute to the overall burden of alcohol misuse in the Armed Forces; however, evidence bearing on this issue is limited. This study examines prevalence and correlates of alcohol misuse among new U.S. Army soldiers. METHODS: Cross-sectional survey data were collected from soldiers reporting for basic combat training. The survey retrospectively assessed lifetime alcohol consumption and substance abuse/dependence, enabling estimation of the prevalence of lifetime binge drinking and heavy drinking in a sample of 30,583 soldiers and of probable alcohol use disorder (AUD) among 26,754 soldiers with no/minimal lifetime use of other drugs...
November 24, 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27857645/la50-in-burn-injuries
#4
K Seyed-Forootan, H Karimi, S A Motevalian, M Momeni, R Safari, M Ghadarjani
Burn injuries put a huge financial burden on patients and healthcare systems. They are the 8th leading cause of mortality and the 13th most common cause of morbidity in our country. We used data from our Burn Registry Program to evaluate risk factors for mortality and lethal area fifty percent (LA50) in all burn patients admitted over two years. We used multiple logistic regressions to identify risk factors for mortality. LA50 is a reliable aggregate index for hospital care quality and a good measure for comparing results, also with those of other countries...
March 31, 2016: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/27854440/experiencing-racial-microaggressions-influences-suicide-ideation-through-perceived-burdensomeness-in-african-americans
#5
David W Hollingsworth, Ashley B Cole, Victoria M O'Keefe, Raymond P Tucker, Chandra R Story, LaRicka R Wingate
Racial microaggressions are a contemporary form of subtle discrimination that occur in everyday exchanges, and are associated with a variety of negative mental health outcomes, including suicide ideation. Previous work (e.g., Torres-Harding, Andrade, & Romero Diaz, 2012) has identified 6 dimensions of racial microaggressions: invisibility, criminality, low-achieving/undesirable culture, sexualization, foreigner/not belonging, and environmental invalidations. The current study examined whether the 6 dimensions of racial microaggressions were associated with increased suicide ideation through perceived burdensomeness and thwarted belongingness among 135 African American young adults...
November 17, 2016: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/27845485/physician-assisted-suicide-and-clinical-vulnerability-a-slippery-slope
#6
F Monacelli, M Martini, P Odetti, R Ciliberti
AIMS: The Belgian case of a 24 years' woman affected by resistant depression, who obtained the legal right to assisted suicide rehearsed ethical issues. From the famous Chabot case of the Dutch court in 1994, accumulating legal evidence indicates that the unbearable psychiatric suffering may be equate to the physical struggle of end of life patients. The Belgian law has addressed assisted suicide as an option in case of unbearable psychic suffering with no future prospective. DESIGN: It is unlikely that the practice of euthanasia may be mechanistically reduced to the provision of a suicide as alleviating the burden of suffering in depression is a long life commitment; moreover, the principle of patient's self determination and autonomy is highly debatable: the closure to the future, the hopelessness and the suicidal ideation represent per se core features of depression...
September 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27836391/diagnosing-and-treating-depression-in-epilepsy
#7
Christian E Elger, Samantha A Johnston, Christian Hoppe
At least one third of patients with active epilepsy suffer from significant impairment of their emotional well-being. A targeted examination for possible depression (irrespective of any social, financial or personal burdens) can identify patients who may benefit from medical attention and therapeutic support. Reliable screening instruments such as the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) are suitable for the timely identification of patients needing help. Neurologists should be capable of managing mild to moderate comorbid depression but referral to mental health specialists is mandatory in severe and difficult-to-treat depression, or if the patient is acutely suicidal...
October 31, 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27816846/bipolar-i-disorder-in-remission-vs-schizophrenia-in-remission-is-there-a-difference-in-burden
#8
Oluyomi Esan, Christopher Osunbote, Oluremi Oladele, Sina Fakunle, Christopher Ehindero, Konstantinos N Fountoulakis
INTRODUCTION: Bipolar disorder (BD) is considered to have a better outcome in comparison to schizophrenia. However, recent data dispute this notion. The current study aimed to compare the burden of patients with BD type I (BD-I) in remission with similar patients with schizophrenia (SZ) in remission. MATERIALS AND METHODS: Patients with schizophrenia (n=75) and BD-I (n=54) aged 18-64years were included in the study. The diagnosis was made with the SCID-I/P. Patients were assessed for sociodemographic variables, stigma, quality of life, disability, suicidality and current symptomatology...
January 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27789949/managing-drug-resistant-epilepsy-challenges-and-solutions
#9
REVIEW
Linda Dalic, Mark J Cook
Despite the development of new antiepileptic drugs (AEDs), ~20%-30% of people with epilepsy remain refractory to treatment and are said to have drug-resistant epilepsy (DRE). This multifaceted condition comprises intractable seizures, neurobiochemical changes, cognitive decline, and psychosocial dysfunction. An ongoing challenge to both researchers and clinicians alike, DRE management is complicated by the heterogeneity among this patient group. The underlying mechanism of DRE is not completely understood. Many hypotheses exist, and relate to both the intrinsic characteristics of the particular epilepsy (associated syndrome/lesion, initial response to AED, and the number and type of seizures prior to diagnosis) and other pharmacological mechanisms of resistance...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27768608/testing-the-interpersonal-theory-of-suicide-in-chronic-pain
#10
Keith G Wilson, Adam Heenan, John Kowal, Peter R Henderson, Lachlan A McWilliams, Dyana Castillo
OBJECTIVES: The interpersonal theory of suicide offers a conceptual framework for understanding suicidal ideation (SI) that may be applicable to individuals with chronic pain. The theory emphasizes the importance of two interpersonal constructs as precursors to SI: perceived burdensomeness (the belief that one has become a burden to others) and thwarted belongingness (a lack of social integration or connection). Our objective was to test the interpersonal theory of suicide in people with chronic pain...
October 20, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27745614/burden-of-violent-death-on-years-of-life-lost-in-rhode-island-2006-2013
#11
Yongwen Jiang, Megan L Ranney, Beatriz Perez, Samara Viner-Brown
INTRODUCTION: Mortality from injuries, particularly violent injuries, is more common among the young. Although traditional epidemiologic measures describe burden of death using rate-related mortalities, this method may not accurately represent burden of premature death. Years of life lost (YLLs) incorporate time discounting and age weighting to more accurately estimate the burden of death. To the authors' knowledge, there has been no examination of YLLs using the Rhode Island Violent Death Reporting System data...
November 2016: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/27741468/illnesses-in-siblings-of-us-patients-with-bipolar-disorder-relate-to-multigenerational-family-history-and-patients-severity-of-illness
#12
Robert M Post, Lori L Altshuler, Ralph Kupka, Susan L McElroy, Mark A Frye, Michael Rowe, Heinz Grunze, Trisha Suppes, Paul E Keck, Willem A Nolen
BACKGROUND: Patients with bipolar disorder from the US have more early-onset illness and a greater familial loading for psychiatric problems than those from the Netherlands or Germany (abbreviated here as Europe). We hypothesized that these regional differences in illness burden would extend to the patients siblings. METHODS: Outpatients with bipolar disorder gave consent for participation in a treatment outcome network and for filling out detailed questionnaires...
October 6, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27733061/temperament-and-character-profiles-of-group-based-suicide-cases
#13
Monique Séguin, Marie Robert, Guy Beauchamp
BACKGROUND: Personality and character traits may be a key predisposing factor to consider in the life course of people who are vulnerable to suicide. AIMS: The aim of this study is first to explore the possible presence of different subgroups of suicide decedents based on developmental profiles of adversity, and secondly to examine the association of personality and character dimensions (covariates) with the trajectory outcome. METHOD: A total of 90 cases of suicide decedents were analyzed using growth mixture modeling (GMM)...
October 12, 2016: Crisis
https://www.readbyqxmd.com/read/27693866/demographic-and-clinical-characteristics-of-current-comorbid-psychiatric-disorders-in-a-randomized-clinical-trial-for-adults-with-stimulant-use-disorders
#14
Diane Warden, Katherine Sanchez, Tracy Greer, Thomas Carmody, Robrina Walker, Adriane Dela Cruz, Marisa Toups, Chad Rethorst, Madhukar H Trivedi
This study aimed to determine if current comorbid psychiatric disorders differ in adults with cocaine use disorder, other stimulant (primarily methamphetamine) use disorder, or both, and identify demographic and clinical characteristics in those with increasing numbers of comorbid disorders. Baseline data from a randomized controlled trial beginning in residential settings (N=302) was used. Mood disorders were present in 33.6%, and anxiety disorders in 29.6%, with no differences among stimulant use disorder groups...
September 15, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27682491/-hospital-costs-and-related-influencing-factors-in-patients-with-acute-poisoning
#15
Y M Ye, F M Wang, C Jin, L L Zhou, D Q Chen
Objective: To investigate the hospital costs and related influencing factors in patients with acute poisoning. Methods: A retrospective analysis was performed for the general status and hospital costs of 373 patients with acute poisoning who were admitted to The Second Affiliated Hospital of Wenzhou Medical College from January 2009 to March 2015. The questionnaires were completed, the data were entered into Excel forms, and SPSS 18.0 was used to perform statistical analysis. Results: Among the 373 patients, 44...
July 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/27681146/clinical-correlates-of-suicidality-among-individuals-with-hiv-infection-and-aids-disease-in-mbarara-uganda
#16
Godfrey Zari Rukundo, Eugene Kinyanda, Brian Mishara
The association between suicidality and HIV/AIDS has been demonstrated for three decades, but little is know about risk factors that can help understand this association and help identify who is most at risk. Few research studies have been conducted in sub-Saharan Africa, a region that accounts for more than 70% of the HIV global burden. This paper describes clinical risk factors for suicidality among individuals with HIV infection and AIDS disease in Mbarara, Uganda. In this study, suicidality includes both suicidal ideation and suicidal attempts...
September 2016: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/27664596/interventions-for-adolescent-mental-health-an-overview-of-systematic-reviews
#17
REVIEW
Jai K Das, Rehana A Salam, Zohra S Lassi, Marium Naveed Khan, Wajeeha Mahmood, Vikram Patel, Zulfiqar A Bhutta
Many mental health disorders emerge in late childhood and early adolescence and contribute to the burden of these disorders among young people and later in life. We systematically reviewed literature published up to December 2015 to identify systematic reviews on mental health interventions in adolescent population. A total of 38 systematic reviews were included. We classified the included reviews into the following categories for reporting the findings: school-based interventions (n = 12); community-based interventions (n = 6); digital platforms (n = 8); and individual-/family-based interventions (n = 12)...
October 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27661557/-mental-health-in-chile-and-finland-challenges-and-lessons
#18
Pedro Retamal C, Niina Markkula, Sebastián Peña
This article analyses and compares the epidemiology of mental disorders and relevant public policies in Chile and Finland. In Chile, a specific mental health law is still lacking. While both countries highlight the role of primary care, Finland places more emphasis on participation and recovery of service users. Comprehensive mental health policies from Finland, such as a successful suicide prevention program, are presented. Both countries have similar prevalence of mental disorders, high alcohol consumption and high suicide rates...
July 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27631148/probable-posttraumatic-stress-disorder-in-the-us-veteran-population-according-to-dsm-5-results-from-the-national-health-and-resilience-in-veterans-study
#19
Blair E Wisco, Brian P Marx, Mark W Miller, Erika J Wolf, Natalie P Mota, John H Krystal, Steven M Southwick, Robert H Pietrzak
OBJECTIVE: With the publication of DSM-5, important changes were made to the diagnostic criteria for posttraumatic stress disorder (PTSD), including the addition of 3 new symptoms. Some have argued that these changes will further increase the already high rates of comorbidity between PTSD and other psychiatric disorders. This study examined the prevalence of DSM-5 PTSD, conditional probability of PTSD given certain trauma exposures, endorsement of specific PTSD symptoms, and psychiatric comorbidities in the US veteran population...
September 13, 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27631141/age-at-onset-of-bipolar-disorder-related-to-parental-and-grandparental-illness-burden
#20
Robert M Post, Lori L Altshuler, Ralph Kupka, Susan L McElroy, Mark A Frye, Michael Rowe, Heinz Grunze, Trisha Suppes, Paul E Keck, Gabriele S Leverich, Willem A Nolen
OBJECTIVE: The age at onset of bipolar disorder varies greatly in different countries and continents. The association between load of family history of psychiatric illness and age at onset has not been adequately explored. METHODS: 979 outpatients with bipolar disorder (from 4 sites in the United States and 3 in the Netherlands and Germany) gave informed consent and completed a questionnaire about their demographics, age at onset of illness, and family history of unipolar and bipolar disorder, alcohol and substance abuse comorbidity, suicide attempts, and "other" illnesses in their parents, 4 grandparents, and any offspring...
September 13, 2016: Journal of Clinical Psychiatry
keyword
keyword
115923
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"