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Anna J McConnell, Catherine M Aitchison, Angela B Grommet, Jonathan R Nitschke
Subcomponent exchange transformed new high-spin Fe(II)4L4 cage 1 into previously-reported low-spin Fe(II)4L4 cage 2: 2-formyl-6-methylpyridine was ejected in favor of the less sterically hindered 2-formylpyridine, with concomitant high- to low-spin transition of the cage's Fe(II) centers. High-spin 1 also reacted more readily with electron-rich anilines than 2, enabling the design of a system consisting of two cages that could release their guests in response to combinations of different stimuli. The addition of p-anisidine to a mixture of high-spin 1 and previously-reported low-spin Fe(II)4L6 cage 3 resulted in the destruction of 1 and the release of its guest...
April 26, 2017: Journal of the American Chemical Society
A Leichtle, D Hollfelder, B Wollenberg, K-L Bruchhage
Endonasal ballon dilatation of the Eustachian tube (BET) is a promising treatment for Eustachian tube dysfunction with encouraging results over the last years in adults. In addition, in children, single studies demonstrated promising results, but revealed the necessity for broader and additional studies. Our retrospective analysis presents outcomes with BET in children with chronic obstructive dysfunction of the Eustachian tube, showing resistance to the conventional therapy after adenotomy with paracentesis or grommets (ventilation tubes)...
March 10, 2017: European Archives of Oto-rhino-laryngology
Angela B Grommet, Jonathan R Nitschke
Supramolecular capsules can now be prepared with a wide range of volumes and geometries. Consequently, many of these capsules encapsulate guests selectively by size and shape, an important design feature for separations. To successfully address practical separations problems, however, a guest cannot simply be isolated from its environment; the molecular cargo must be removed to a separate physical space. Here we demonstrate that an Fe(II)4L4 coordination cage 1 can transport a cargo spontaneously and quantitatively from water across a phase boundary and into an ionic liquid layer...
February 2, 2017: Journal of the American Chemical Society
Sadik Quoraishi, Jayan George, Amir Farboud, Conor Marnane
Bezold's and Citelli's abscesses are rare complications of otitis media. We present a case of a 44-year-old Eastern European man, with a history of recurrent otitis media, who was admitted to hospital with mastoiditis and initially treated with antibiotics. Despite clinical improvement, a CT scan showed mastoiditis with Bezold's and Citelli's abscesses. The patient underwent a myringotomy and grommet insertion, in addition to a cortical mastoidectomy and curettage of the neck abscesses. After a good recovery, he was discharged home...
January 17, 2017: BMJ Case Reports
Revadi Govindaraju, Meenakshi Adaikappan, Raman Rajagopalan
BACKGROUND: Baro-otalgia is a common complaint among passengers in an aircraft, in particular those who had a recent upper respiratory tract infection. The underlying pathophysiology is secondary to unequal aeration of the middle ear cleft with the surrounding atmosphere and it can be explained using Boyle's Law. We describe an unusual presentation of baro-otalgia in a pilot secondary to cholesteatoma obstructing the aditus despite normal middle ear pressure equalization provided by a grommet in the ear...
January 1, 2017: Aerospace Medicine and Human Performance
Roderick P Venekamp, Faisal Javed, Thijs Ma van Dongen, Angus Waddell, Anne Gm Schilder
BACKGROUND: Ear discharge (otorrhoea) is common in children with grommets (ventilation/tympanostomy tubes); the proportion of children developing discharge ranges from 25% to 75%. The most common treatment strategies include oral broad-spectrum antibiotics, antibiotic eardrops or those containing a combination of antibiotic(s) and a corticosteroid, and initial observation. Important drivers for one strategy over the other are concerns over the side effects of oral antibiotics and the potential ototoxicity of antibiotic eardrops...
November 17, 2016: Cochrane Database of Systematic Reviews
Louise Vaile, Tim Williamson, Angus Waddell, Gordon J Taylor
BACKGROUND: The insertion of grommets (also known as ventilation or tympanostomy tubes) is one of the most common surgical procedures performed on children. Postoperative otorrhoea (discharge) is the most common complication with a reported incidence ranging from 10% to 50%. In the UK, many ENT surgeons treat with topical antibiotics/steroid combinations, but general practitioners, mainly through fears of ototoxicity, are unlikely to prescribe these and choose systemic broad-spectrum antibiotics...
November 15, 2016: Cochrane Database of Systematic Reviews
Wenchao Gao, Wenyu Liang, Kok Kiong Tan
To treat a worldwide common ear disease (OME), a device allowing fast grommet tube insertion has been designed in our earlier works (Gao et al., 2015 [1] and Liang et al., 2013 [2]). However, the instrument has to be manually placed as close as to the Tympanic Membrane before the insertion procedures. To realize a fully automated surgical process, the instrument shall be automatically manipulated to align to the axial direction of ear canal and proceed to complete the surgery. A vision-based servomechanism is proposed to solve the path planning problem...
October 5, 2016: ISA Transactions
M Khalid-Raja, K Tzifa
OBJECTIVE: This study aimed to evaluate the activity of paediatric otolaryngology services required for children with Down's syndrome in a tertiary referral centre. METHODS: A review of the paediatric otolaryngology input for children with Down's syndrome was performed; data were obtained from the coding department for a two-year period and compared with other surgical specialties. RESULTS: Between June 2011 and May 2013, 106 otolaryngology procedures were performed on children with Down's syndrome...
November 2016: Journal of Laryngology and Otology
Vasileios Gkiousias, Christopher Collett Butler, Victoria Shepherd, James Michael Kilgour, Cherry-Ann Waldron, Emma Thomas-Jones, Nick Francis
OBJECTIVES: Otitis media with effusion (OME) is a common cause of hearing loss and possible developmental delay in children, and there are a range of 'preference sensitive' treatment options. We aimed to evaluate the attitudes and beliefs of parents of affected children to treatment options including watchful-waiting, hearing aids, grommets, and, oral steroids with the intention of developing our understanding of decision-making and the factors influencing it, sources of parental information, and satisfaction with information provision...
October 2016: International Journal of Pediatric Otorhinolaryngology
Faisal R Ali, Emma E Craythorne
No abstract text is available yet for this article.
September 2016: Journal of the American Academy of Dermatology
Zahir Mughal, Vijay Thirunavukarasu, Adnan Darr, Mudit Jindal
BACKGROUND: Grommet insertion is a common procedure in children. A lengthy otolaryngology follow-up can have an adverse impact on clinic waiting times, new patient appointment availability, and pecuniary disadvantage for the hospital. OBJECTIVE OF REVIEW: To consolidate research and opinion concerning follow-up care following grommet insertion in a pediatric population. SEARCH STRATEGY: The literature between January 1990 and September 2015 was searched on MEDLINE (Ovid), Google Scholar, PubMed and Web of Science databases...
September 2016: International Journal of Pediatric Otorhinolaryngology
Klemens Trieb
The treatment of metacarpophalangeal destruction by rheumatoid arthritis is often an indication for joint replacement, here the swanson spacer still has his place. The flexible spacer may be implanted with or without titanium guide sleeves ("grommets"). However, the imaginary abrasion protection for the silicone grommets may in turn lead through micro-movements to wear as it is observed in the case shown here. PATIENTS AND METHODS: One over a period of 30 years suffering from rheumatoid arthritis 69 years old female patient is presented...
July 8, 2016: Current Rheumatology Reviews
T Tikka, A Opeodu, R Irving, J Murphy
BACKGROUND: Cerebrospinal fluid otorrhoea is a rare entity. Only a few cases of spontaneous bilateral cerebrospinal fluid otorrhoea have been reported. In all cases, there was a definite time interval between the two (left and right) presentations. OBJECTIVES: To raise awareness and report on the very rare entity of bilateral spontaneous cerebrospinal fluid otorrhoea. CASE REPORT: This paper reports the case of a bilateral, synchronous, spontaneous cerebrospinal fluid otorrhoea in a 44-year-old female...
August 2016: Journal of Laryngology and Otology
Chin-Kuo Chen, Jui Fang, Yung-Liang Wan, Po-Hsiang Tsui
Ultrasound detection of middle ear effusion (MEE) is an emerging technique in otolaryngology. This study proposed using ultrasound characterization of the mastoid to noninvasively measure MEE-induced mastoid effusion (ME) as a new strategy for determining the presence of MEE. In total, 53 patients were enrolled (Group I: normal, n = 20; Group II: proven MEE through both otoscopy and tympanometry, n = 15; Group III: patients with MEE having effusions observed during grommet surgery, n = 18). A 2...
2016: Scientific Reports
Rachel Easto, Rishi Shukla, Charlie Rowland, Richard Williams
Paediatric grommet insertions are a common ENT procedure which is typically carried out as a daycase procedure. National guidelines exist (NICE CG60) outlining the criteria for grommet insertions. At our institution it was noted that children were experiencing long waits for their grommet surgery with 78% breaching the national 18 week RTT target by time of surgery in the preceding 6 months. 38% of children were attending for surgery with out of date audiograms and as a consequence, due to children no longer meeting the NICE criteria for grommet insertions, 8% of children were being cancelled on the day of surgery...
2016: BMJ Quality Improvement Reports
Konstantinos Markou, Marios Stavrakas, Petros Karkos, Georgios Psillas
Otosclerosis in childhood and adolescence or juvenile otosclerosis is a rare disorder resulting in conductive hearing loss. A 9-year-old boy presented to our clinic, suffering from moderate hearing loss. According to his parents, his hearing acuity had progressively deteriorated over the past 2 years. Otoscopy and tympanometry revealed bilateral secretory otitis media and the patient underwent bilateral grommet insertion. However, he continued to report of hearing loss and a right exploratory tympanotomy was performed...
2016: BMJ Case Reports
Stephen L Barrett
This case illustrates the complexity and interrelationship of osseous pathology with peripheral nerve entrapment and neuromata. She had an iatrogenic nerve injury of a branch of the medial dorsal cutaneous nerve causing her painful scar. Secondarily, she developed an injury to her common peroneal nerve from the cast immobilization, resulting in palsy/drop foot. The tarsal tunnel entrapment was likely a sequela of the cast immobilization and chronic swelling. Her postoperative chronic pain was compounded by the failure to use grommets with the polymeric silicon (Silastic) implant at the initial surgery, leading to a breakdown of the implant with subsequent detritic synovitis...
April 2016: Clinics in Podiatric Medicine and Surgery
Wafaa A Kaf, Enass S Mohamed, Hamza Elshafiey
PURPOSE: Accurate estimation of mild, low-frequency hearing loss is difficult in young children. This study aimed to determine the accuracy of 40-Hz sinusoidal auditory steady-state response (sASSR) compared with tone burst auditory brainstem response (TB-ABR) to detect mild, low-frequency hearing loss in children with otitis media with effusion and to measure postoperative thresholds. METHODS: Thresholds at 500 and 4000 Hz were measured behaviorally and electrophysiologically using TB-ABR and 40-Hz sASSR with a Kalman filter in 26 children with otitis media with effusion...
March 2016: American Journal of Audiology
Rupert G Ricks, Rachel Easto, Venkat M Reddy
The insertion of middle ear ventilation tubes remains one of the most common procedures for ENT surgeons. A common concern amongst patients undergoing such procedures is the effect on their ability to partake in swimming and other water sports. Currently there is little evidence comparing the penetration ability of different water solutions encountered by swimmers. This study compares the water penetration of four different water solutions for Shah, mini-Shah, T tube and titanium bobbin ventilation tubes. A model was constructed to replicate a grommet inserted through a tympanic membrane using a syringe barrel, latex membrane and one of the ventilation tubes...
October 2016: European Archives of Oto-rhino-laryngology
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