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https://www.readbyqxmd.com/read/28631020/utility-of-pas-and-%C3%AE-catenin-staining-in-histological-categorisation-and-prediction-of-prognosis-of-hepatoblastomas
#1
Goutam Bera, Ram Narayan Das, Paromita Roy, Ranajoy Ghosh, Nelofar Islam, Prafulla Kumar Mishra, Uttara Chatterjee
AIMS: The aim of this study was to assess the usefulness of PAS, β-catenin and Ki-67 in categorising hepatoblastomas (HBs) and their significance in predicting prognosis. In addition, we have also documented the various chemotherapy induced histologic changes in HBs. METHOD: In this retrospective observational study of 29 cases of hepatoblastomas, 27 cases were considered for statistical analysis, excluding two cases of diagnostic core biopsies. All clinicopathological parameters and follow up data were collected...
June 19, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28607889/outcomes-of-newborn-hearing-screening-program-a-hospital-based-study
#2
Kavita Sachdeva, Tulsi Sao
Hearing loss is hidden disability and second most common congenital pathology. Prevention, early identification and early intervention of hearing loss can prevent further disability in development of speech, language, cognition and other developmental domains. The prevalence of congenital hearing loss has been estimated to be 1.2-5.7 per thousand in neonates. In these contexts, the aim of study was to determine outcomes of neonates hearing screening program in Hospital. It is a clinical cross-sectional study which was conducted in tertiary care centre from 8th July, 2015 to 31th May, 2016...
June 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28604358/dual-stage-beamforming-in-absence-of-front-end-receive-focusing
#3
Deep Bera, Johan Bosch, Martin Verweij, Nico De Jong, Hendrik Vos
Ultrasound front-end receive designs for miniature, wireless, and/or matrix transducers might be simplified considerably by direct element summation in receive. In this paper we develop a dual-stage beamforming technique which is able to produce a high quality image from scanlines that are produced with focused transmit, and simple summation in receive (no delays). We call this Non-Delayed Sequential Beamforming (NDSB). In the first stage, low-resolution RF scanlines are formed by simple summation of element signals from a running sub-aperture...
June 12, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28599607/the-accuracy-of-objective-threshold-determination-at-low-frequencies-comparison-of-different-auditory-brainstem-response-abr-and-auditory-steady-state-response-assr-methods
#4
Jacqueline Frank, Izet Baljić, Sebastian Hoth, Dirk Eßer, Orlando Guntinas-Lichius
OBJECTIVE: The hearing threshold at 500 Hz was estimated using five methods which are suitable for the low frequency range: Low-Chirp BERA (LCBERA), Notched-noise BERA (NNBERA), Narrow band CE-Chirp BERA (NBCBERA) and Narrow band CE-Chirp ASSR (NBCASSR) (40/90 Hz). The slope of the discrimination function of each method was used for determination of the most efficient method. The threshold values were compared and the corresponding odds ratios (OR) were calculated. DESIGN: All methods were applied to each subject...
May 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28594387/3d-printing-based-integrated-water-quality-sensing-system
#5
Muinul Banna, Kaustav Bera, Ryan Sochol, Liwei Lin, Homayoun Najjaran, Rehan Sadiq, Mina Hoorfar
The online and accurate monitoring of drinking water supply networks is critically in demand to rapidly detect the accidental or deliberate contamination of drinking water. At present, miniaturized water quality monitoring sensors developed in the laboratories are usually tested under ambient pressure and steady-state flow conditions; however, in Water Distribution Systems (WDS), both the pressure and the flowrate fluctuate. In this paper, an interface is designed and fabricated using additive manufacturing or 3D printing technology-material extrusion (Trade Name: fused deposition modeling, FDM) and material jetting-to provide a conduit for miniaturized sensors for continuous online water quality monitoring...
June 8, 2017: Sensors
https://www.readbyqxmd.com/read/28589503/promise-of-adeno-associated-virus-as-a-gene-therapy-vector-for-cardiovascular-diseases
#6
REVIEW
Abesh Bera, Dwaipayan Sen
Cardiovascular diseases pose a unique threat to global mortality because it presents as one of the most diverse conglomerations of pathophysiological conditions that can create significant casualty even without straying into its collateral damage. This puts them right beside obesity and cancer in terms of severity. Their pervasive nature and high prevalence prompted biologists to seek newer prophylactic avenues of addressing this global hazard, among which adeno-associated virus (AAV) gene therapy rose to significant prominence...
June 7, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28587495/allele-specific-interaction-between-glutathione-peroxidase-1-and-manganese-superoxide-dismutase-affects-the-levels-of-bcl-2-sirt3-and-e-cadherin
#7
Dede N Ekoue, Soumen Bera, Emmanuel Ansong, Peter C Hart, Sofia Zaichick, Frederick E Domann, Marcelo G Bonini, Alan M Diamond
Manganese superoxide dismutase (MnSOD) is a mitochondrial resident enzyme that reduces superoxide to hydrogen peroxide (H2O2), which can be further reduced to water by glutathione peroxidase (GPX1). Data from human studies has indicated that common polymorphisms in both of these proteins are associated with the risk of several cancers, including breast cancer. Moreover, polymorphisms in MnSOD and GPX1 were shown to interact to increase the risk of breast cancer. To gain an understanding of the molecular mechanisms behind these observations, we engineered human MCF-7 breast cancer cells to exclusively express GPX1 and/or MnSOD alleles and investigated the consequences on the expression of several proteins associated with cancer etiology...
June 6, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28566415/a-rare-cause-of-anuria-in-a-case-of-pre-b-acute-lymphoblastic-leukaemia
#8
Siddhesh Arun Kalantri, Rahul Singla, Malay Kumar Bera, Maitreyee Bhattyacharyya
Renal failure in cases of acute lymphoblastic leukaemia during induction is mainly because of sepsis and tumour lysis syndrome. This 18-year-old man had sudden onset anuria with increase in creatine. At this time, patient did not have any overt signs or laboratory features suggestive of sepsis. Imaging studies documented bilateral hydronephrosis. Ureteroscopy was done, and it showed presence of soft tissue mass obstructing the ureter. On the the left side, it was noted in its middle part and on the right, at the ureteropelvic junction...
May 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28561828/leveraging-a-temperature-tunable-scale-like-microstructure-to-produce-multimodal-supersensitive-sensors
#9
Yanlong Tai, Tushar Kanti Bera, Zhenguo Yang, Gilles Lubineau
The microstructure of a flexible film plays an important role in its sensing capability. Here, we fabricate a temperature-dependent wrinkled single-walled carbon nanotube (SWCNT)/polydimethyl-siloxane (PDMS) film (WSPF) and a wrinkle-dependent scale-like SWCNT/PDMS film (SSPF) successfully, and address the formation and evolution mechanisms of each film. The low elastic modulus and high coefficient of thermal expansion of the PDMS layer combined with the excellent piezoresistive behavior of the SWCNT film motivated us to investigate how the scale-like microstructure of the SSPF could be used to design multimodal-sensing devices with outstanding capabilities...
May 31, 2017: Nanoscale
https://www.readbyqxmd.com/read/28551147/ft-mir-supported-electrical-impedance-spectroscopy-based-study-of-sugar-adulterated-honeys-from-different-floral-origin
#10
Chirantan Das, Subhadip Chakraborty, Krishnendu Acharya, Nirmal Kumar Bera, Dipankar Chattopadhyay, Anupam Karmakar, Sanatan Chattopadhyay
This study sought to detect the presence of sucrose as an adulterant in selected honey varieties from different floral origins by employing Electrical Impedance Spectroscopy (EIS) technique which has been simultaneously supported by Fourier Transform-Mid Infrared Spectroscopy (FT-MIR) measurements to provide a rapid, robust yet simple platform for honey quality evaluation. Variation of electrical parameters such as impedance, capacitance and conductance for 10%, 20%, 30%, 40%, 50%, 60% and 70% (w/w) sucrose syrup (SS) adulterated honey samples are analyzed and their respective current-voltage (I-V) characteristics are studied...
August 15, 2017: Talanta
https://www.readbyqxmd.com/read/28548510/density-propagator-for-many-body-localization-finite-size-effects-transient-subdiffusion-and-exponential-decay
#11
Soumya Bera, Giuseppe De Tomasi, Felix Weiner, Ferdinand Evers
We investigate charge relaxation in quantum wires of spinless disordered fermions (t-V model). Our observable is the time-dependent density propagator Π_{ϵ}(x,t), calculated in windows of different energy density ϵ of the many-body Hamiltonian and at different disorder strengths W, not exceeding the critical value W_{c}. The width Δx_{ϵ}(t) of Π_{ϵ}(x,t) exhibits a behavior dlnΔx_{ϵ}(t)/dlnt=β_{ϵ}(t), where the exponent function β_{ϵ}(t)≲1/2 is seen to depend strongly on L at all investigated parameter combinations...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28546537/basin-stability-for-chimera-states
#12
Sarbendu Rakshit, Bidesh K Bera, Matjaž Perc, Dibakar Ghosh
Chimera states, namely complex spatiotemporal patterns that consist of coexisting domains of spatially coherent and incoherent dynamics, are investigated in a network of coupled identical oscillators. These intriguing spatiotemporal patterns were first reported in nonlocally coupled phase oscillators, and it was shown that such mixed type behavior occurs only for specific initial conditions in nonlocally and globally coupled networks. The influence of initial conditions on chimera states has remained a fundamental problem since their discovery...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28536705/role-of-gntr-family-regulatory-gene-sco1678-in-gluconate-metabolism-in-streptomyces-coelicolor-m145
#13
Olga Tsypik, Roman Makitrynskyy, Agnieszka Bera, Lijiang Song, Wolfgang Wohlleben, Victor Fedorenko, Bohdan Ostash
Here we report functional characterization of the Streptomyces coelicolor M145 gene SCO1678, which encodes a GntR-like regulator of the FadR subfamily. Bioinformatic analysis suggested that SCO1678 is part of putative operon (gnt) involved in gluconate metabolism. Combining the results of SCO1678 knockout, transcriptional analysis of gnt operon, and Sco1678 protein-DNA electromobility shift assays, we established that Sco1678 protein controls the gluconate operon. It does so via repression of its transcription from a single promoter located between genes SCO1678 and SCO1679...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28529377/depression-in-mothers-of-the-mentally-retarded-patients-need-to-look-deeper
#14
Sagar Chandra Bera
No abstract text is available yet for this article.
January 2017: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28523326/hashimoto-s-thyroiditis-associated-with-thyroid-adenoma-with-h%C3%A3-rthle-cells-case-report
#15
Mihaela Stanciu, Liana Gabriela Bera, Mihaela Popescu, Florin Grosu, Florina Ligia Popa
Chronic thyroiditis may present a focal lesion, often-palpable abnormality, simulating nodular disease. The number and morphology of the Hürthle cells (HC) vary in the thyroid aspirate. Distinguishing between neoplastic and non-neoplastic HC lesions is difficult when using the fine-needle aspiration cytology (FNAC). We present the case of a 46-year-old female with a large right nodular goiter and hypothyroidism and high titer of anti-thyroid peroxidase antibody (TPO). The thyroid ultrasound showed a large well-defined nodule (more than 6...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28489112/an-efficient-charge-separation-and-photocurrent-generation-in-the-carbon-dot-zinc-oxide-nanoparticle-composite
#16
Monoj Kumar Barman, Piyali Mitra, Rajesh Bera, Somnath Das, Amitava Pramanik, Amitava Parta
The development of light harvesting systems based on heterostructures for efficient conversion of solar energy to renewable energy is an emerging area of research. Here, we have designed heterostructures by using carbon dots (C-dots) and zinc oxide nanoparticles (ZnO NP) to develop an efficient light harvesting system. Interestingly, the conduction band and the valence band positions of ZnO NP are lower than the LUMO and HOMO positions of C-dots in this type II heterostructure of C dot-ZnO NP, which causes efficient charge separation and photocurrent generation...
May 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28488658/walker-warburg-syndrome-with-gonadal-dysgenesis-a-rare-association
#17
Goutam Bera, Aniket Halder, Bappa Mandal, Ram Narayan Das, Suchandra Mukherjee, Uttara Chatterjee
No abstract text is available yet for this article.
May 2017: Neurology India
https://www.readbyqxmd.com/read/28487688/gamma-glutamylpolyamine-synthetase-glna3-is-involved-in-the-first-step-of-polyamine-degradation-pathway-in-streptomyces-coelicolor-m145
#18
Sergii Krysenko, Nicole Okoniewski, Andreas Kulik, Arne Matthews, Jan Grimpo, Wolfgang Wohlleben, Agnieszka Bera
Streptomyces coelicolor M145 was shown to be able to grow in the presence of high concentrations of polyamines, such as putrescine, cadaverine, spermidine, or spermine, as a sole nitrogen source. However, hardly anything is known about polyamine utilization and its regulation in streptomycetes. In this study, we demonstrated that only one of the three proteins annotated as glutamine synthetase-like protein, GlnA3 (SCO6962), was involved in the catabolism of polyamines. Transcriptional analysis revealed that the expression of glnA3 was strongly induced by exogenous polyamines and repressed in the presence of ammonium...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28487073/a-minimalistic-tetrapeptide-amphiphile-scaffold-for-transmembrane-pores-with-a-preference-for-sodium
#19
Debajyoti Basak, Sucheta Sridhar, Amal K Bera, Nandita Madhavan
Synthetic channels or pores that are easy to synthesize, stable and cation-selective are extremely attractive for the development of therapeutics and materials. Herein, we report a pore developed from a small tetrapeptide scaffold that shows a preference for sodium over lithium/potassium. The sodium selectivity is attributed to the appended oligoether tail at the C-terminus. A peptide dimer is proposed as the predominant cation-transporting pore. Such pyridine containing stable pores can be potentially utilized for the pH modulated ion transport...
April 27, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28482582/core-shell-alginate-ghatti-gum-modified-montmorillonite-composite-matrices-for-stomach-specific-flurbiprofen-delivery
#20
Hriday Bera, Sohitha Reddy Ippagunta, Sanoj Kumar, Pavani Vangala
Novel alginate-arabic gum (AG) gel membrane coated alginate-ghatti gum (GG) modified montmorillonite (MMT) composite matrices were developed for intragastric flurbiprofen (FLU) delivery by combining floating and mucoadhesion mechanisms. The clay-biopolymer composite matrices containing FLU as core were accomplished by ionic-gelation technique. Effects of polymer-blend (alginate:GG) ratios and crosslinker (CaCl2) concentrations on drug entrapment efficiency (DEE, %) and cumulative drug release after 8h (Q8h, %) were studied to optimize the core matrices by a 3(2) factorial design...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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