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Thayse Bienert Goetze, Pricila Sleifer, Rafael Fabiano Machado Rosa, Alessandra Pawelec da Silva, Carla Graziadio, Paulo Ricardo Gazzola Zen
Oculoauriculovertebral spectrum (OAVS), also known as Goldenhar syndrome, is considered a condition associated to failing of embryogenesis involving the first and second branchial arches, leading to structural abnormalities arising from it. The aim of this study is to verify the hearing features presented by patients with OAVS and provide additional information that may contribute to improvement of speech therapy. The sample consisted of 10 individuals diagnosed with OAVS and cared for by the Clinical Genetics Service...
October 24, 2016: American Journal of Medical Genetics. Part A
Bera Rammohan, Karmakar Samit, Das Chinmoy, Saha Arup, Kundu Amit, Sarkar Ratul, Karmakar Sanmoy, Adhikari Dipan, Sen Tuhinadri
BACKGROUND: Traditionally GS is used to treat diabetes mellitus. Drug-herb interaction of GS via cytochrome P450 enzyme system by substrate cocktail method using HLM has not been reported. OBJECTIVE: To evaluate the in-vitro modulatory effects of GS extracts (aqueous, methanol, ethyl acetate, chloroform and n-hexane) and deacylgymnemic acid (DGA) on human CYP1A2, 2C8, 2C9, 2D6 and 3A4 activities in HLM. MATERIAL AND METHODS: Probe substrate-based LCMS/MS method was established for all CYPs...
July 2016: Pharmacognosy Magazine
Debojit Gogoi, Dilip Kumar Pal, Malay K Bera
Laparoscopic donor nephrectomy (LDN) can be performed via either transperitoneal or retroperitoneal approach. Very few studies have been carried out till now, comparing immunologic and inflammatory responses in donors after these two approaches. This is a prospective observational study. Selection of approach was decided by the operating surgeon. All patients underwent peripheral venous blood sampling preoperatively and 24 h postoperatively for the measurement of C-reactive protein (CRP), interleukein-6 (IL-6), total leukocyte count (TLC), blood urea nitrogen (BUN), and serum creatinine (SCr)...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
Soumen Bera, Sanjay Lamba, Mubasher Rashid, Anuj K Sharma, Alexander B Medvinsky, Claudia Acquisti, Amit Chakraborty, Bai-Lian Li
Impaired glutamate dehydrogenase (GDH) sensitivity to its inhibitors causes excessive insulin secretion by pancreatic beta-cells and defective ammonia metabolism in the liver. These symptoms are commonly associated with hyperinsulinism/hyperammonemia syndrome (HI/HA), which causes recurrent hypoglycaemia in early infancy. Hepatic localization of GDH amination and deamination activities linked with the urea cycle is known to be involved in ammonia metabolism and detoxification. Although deamination activities of hepatic GDH in the periportal zones of liver lobules and its connection to the urea cycle have been exhaustively investigated, physiological roles of GDH amination activity observed at pericentral zones have often been overlooked...
October 17, 2016: Integrative Biology: Quantitative Biosciences From Nano to Macro
Tapas Paul, Subhas Chandra Bera, Nidhi Agnihotri, Padmaja P Mishra
A remarkable observation about adsorption and desorption mechanism of single-stranded oligo nucleotides and hybridization of double stranded DNA (ds-DNA) on graphene oxide (GO) surface has been monitored using ensemble and single molecule fluorescence methods. The probe and target DNA, both labeled individually with fluorescence resonance energy transfer (FRET) pair and having similar adsorption affinity towards the GO surface are used to provide the detailed insight into the hybridization mechanism. The single molecule-FRET (sm-FRET) results reveals the DNA hybridization mechanism to happen "in situ", i...
October 17, 2016: Journal of Physical Chemistry. B
Manjur O Akram, Saibal Bera, Nitin T Patil
A strategy based on tandem alkynylation of o-hydroxyarylenaminones followed by intramolecular cyclization has been developed to generate a diverse array of 3-alkynyl chromones. The functionality embedded in these key intermediates enables their facile elaboration into more diverse structures by a variety of functionalizations and ring-forming processes.
October 11, 2016: Chemical Communications: Chem Comm
Jayeeta Sarkar, Sufia K Kazy, Abhishek Gupta, Avishek Dutta, Balaram Mohapatra, Ajoy Roy, Paramita Bera, Adinpunya Mitra, Pinaki Sar
Nutrient deficiency severely impairs the catabolic activity of indigenous microorganisms in hydrocarbon rich environments (HREs) and limits the rate of intrinsic bioremediation. The present study aimed to characterize the microbial community in refinery waste and evaluate the scope for biostimulation based in situ bioremediation. Samples recovered from the wastewater lagoon of Guwahati refinery revealed a hydrocarbon enriched [high total petroleum hydrocarbon (TPH)], oxygen-, moisture-limited, reducing environment...
2016: Frontiers in Microbiology
D J Muccigrosso, N M Maughan, H Wan, Y Lu, H Schultejans, R Bera, P J Parikh
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
K Grantham, H Wan, N M Maughan, D J Muccigrosso, H Schultejans, R Bera, P J Parikh
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
N M Maughan, D J Muccigrosso, H Schultejans, R Bera, P J Parikh
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
M-S Agier, C Lengellé, T Bejan-Angoulvant, F Beau-Salinas, A-P Jonville-Béra
No abstract text is available yet for this article.
September 22, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Bastab Ghosh, Deepak K Biswal, Malay K Bera, Dilip K Pal
INTRODUCTION: Vesicovaginal fistula (VVF) is the most common type of urogenital fistula. Gynecologic surgery is the most common cause associated with it. Laparoscopic approach for VVF repair gives the benefit of minimally invasive surgery with principles similar to open transabdominal approach. MATERIALS AND METHODS: We retrospectively reviewed data of 13 patients who underwent laparoscopic vesicovaginal repair at our department from December 2012 to December 2014...
October 2016: Journal of Obstetrics and Gynaecology of India
Santanu Ghosh, Nabanita Kar, Tanmoy Bera
Oleanolic acid (OA) has low aqueous solubility and low permeability, which results poor bioavailability. To surmount the inadequacy, our aim was to fabricate oleanolic acid loaded poly lactic co- glycolic acid (PLGA)- d-α- tocopheryl polyethylene glycol 1000 succinate (TPGS) nanoparticles, which could be efficacious for the treatment of Leishmania donovani mediated visceral leishmaniasis (VL). OA loaded PLGA- TPGS nanoparticles were prepared by emulsion solvent evaporation technique. Cellular uptake was investigated...
September 17, 2016: International Journal of Biological Macromolecules
Goutam Bera, Ram Narayan Das, Nelofar Islam, Paromita Roy, Prafulla Kumar Mishra, Chhanda Datta, Manoj Kumar Chaudhuri, Uttara Chatterjee
Hepatoblastoma is the most common primary malignant hepatic tumour of infancy and early childhood. Histologically hepatoblastomas are categorized into pure epithelial and mixed epithelial-mesenchymal types and epithelial type is further subcategorized into pure fetal type, fetal and embryonal type, pure embryonal, and small cell types. This categorization has been shown to have prognostic and therapeutic implication. Fine needle aspiration cytology (FNAC) is useful in pre-operative diagnosis and categorization in most cases of hepatoblastomas...
September 15, 2016: Diagnostic Cytopathology
Sudipta K Bera, Avinash Kumar, Souvik Sil, Tushar Kanti Saha, Tanumoy Saha, Ayan Banerjee
We trap absorbing micro-particles in air by photophoretic forces generated using a single loosely focused Gaussian trapping beam. We measure a component of the radial Brownian motion of a trapped particle cluster and determine the power spectral density, mean squared displacement, and normalized position and velocity autocorrelation functions to characterize the photophoretic body force in a quantitative fashion for the first time. The trapped particles also undergo spontaneous rotation due to the action of this force...
September 15, 2016: Optics Letters
Sagar Suman Panda, Venkata Varaha Bera Ravi Kumar, Sarwar Beg, Sunil Kumar Sahu, Swayamprabha Muni
A stability-indicating liquid chromatographic method was developed employing the principles of quality by design (QbD) to quantify vilazodone hydrochloride (VLN) in pharmaceutical dosage form. A Box-Behnken experimental design was employed to establish optimum conditions including method robustness by selecting organic phase proportion (%), mobile phase flow rate (mL/min) and pH of buffer as the factors, to study their effect on plate number as the response variable. Chromatography was performed on a C-18 column using methanol:phosphate buffer of pH 7...
September 6, 2016: Journal of Chromatographic Science
Abeer Hashem, E F Abd Allah, A A Alqarawi, A A Al-Huqail, M A Shah
The role of soil microbiota in plant stress management, though speculated a lot, is still far from being completely understood. We conducted a greenhouse experiment to examine synergistic impact of plant growth promoting rhizobacterium, Bacillus subtilis (BERA 71), and arbuscular mycorrhizal fungi (AMF) (Claroideoglomus etunicatum; Rhizophagus intraradices; and Funneliformis mosseae) to induce acquired systemic resistance in Talh tree (Acacia gerrardii Benth.) against adverse impact of salt stress. Compared to the control, the BERA 71 treatment significantly enhanced root colonization intensity by AMF, in both presence and absence of salt...
2016: BioMed Research International
M Scheich, D Ehrmann-Müller, W Shehata-Dieler, R Hagen
OBJECTIVE: The aim of this study was to evaluate the hearing results after surgery for T1 and T2 vestibular schwannomas (VS) via the middle cranial fossa (MCF) approach at one institution and to review outcomes in the recent literature. PATIENTS AND METHODS: In our department, 208 consecutive patients have undergone surgery using the MCF approach between December 2005 and February 2015. Audiological testing included pure-tone audiometry, speech-discrimination-tests pre- and postoperatively, as well as a pre- and intraoperative brainstem evoked response audiometry (BERA)...
September 2, 2016: HNO
Indrani Pal, Varsha P Brahmkhatri, Swapna Bera, Dipita Bhattacharyya, Yasrib Quirishi, Anirban Bhunia, Hanudatta S Atreya
The conjugation of nanoparticles with antimicrobial peptides (AMP) is emerging as a promising route to achieve superior antimicrobial activity. However, the nature of peptide-nanoparticle interactions in these systems remains unclear. This study describes a system consisting of a cysteine containing antimicrobial peptide conjugated with silver nanoparticles, in which the two components exhibit a dynamic interaction resulting in a significantly enhanced stability and biological activity compared to that of the individual components...
December 1, 2016: Journal of Colloid and Interface Science
Bidesh K Bera, Dibakar Ghosh, Tanmoy Banerjee
In this paper, we report the occurrence of chimera patterns in a network of neuronal oscillators, which are coupled through local, synaptic gradient coupling. We discover a new chimera pattern, namely the imperfect traveling chimera state, where the incoherent traveling domain spreads into the coherent domain of the network. Remarkably, we also find that chimera states arise even for one-way local coupling, which is in contrast to the earlier belief that only nonlocal, global, or nearest-neighbor local coupling can give rise to chimera state; this find further relaxes the essential connectivity requirement of getting a chimera state...
July 2016: Physical Review. E
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