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https://www.readbyqxmd.com/read/29160374/study-of-the-protective-effect-of-dexamethasone-on-cisplatin-induced-ototoxicity-in-rats
#1
Isabelle Oliveira Jatai Capelo, Avner Marcos Alves Batista, Yuri Neyson Ferreira Brito, Krissia Braga Diniz, Gerly Anne de Castro Brito, Marcos Rabelo de Freitas
PURPOSE: To evaluate the ability of dexamethasone to protect against cisplatin (CDDP)-induced ototoxicity. METHODS: Male Wistar rats were divided into the following three groups: 1) Control (C): 6 animals received intraperitoneal (IP) saline solution, 8 ml/kg/day for four days; 2) C + CDDP: 11 animals received 8 ml/kg/day of IP saline and, 90 min after saline administration, 8 mg/kg/day of IP CDDP for four days; and 3) DEXA15 + CDDP: 11 animals received IP dexamethasone 15 mg/kg/day and, 90 min after dexamethasone administration, received 8 mg/kg/day of IP CDDP for four days...
October 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29149102/recombinant-immunotoxins-targeting-b-cell-maturation-antigen-are-cytotoxic-to-myeloma-cell-lines-and-myeloma-cells-from-patients
#2
T K Bera, Y Abe, T Ise, A Oberle, D Gallardo, X-F Liu, S Nagata, M Binder, I Pastan
No abstract text is available yet for this article.
November 17, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/29142063/first-person-arijita-ghosh
#3
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Arijita Ghosh is the first author on "Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca(2+) leak in HEK293 cells", published in Journal of Cell Science. Arijita is a PhD student in the laboratory of Amal Kanti Bera at the Indian Institute of Technology Madras, Chennai, India, investigating the role of leucine-rich repeat-containing 8 proteins in cellular calcium homeostasis...
November 15, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29138774/exploring-the-effect-of-substituent-in-the-hydrazone-ligand-of-a-family-of-%C3%AE-oxidodivanadium-v-hydrazone-complexes-on-structure-dna-binding-and-anticancer-activity
#4
Debashis Patra, Subhabrata Paul, Indira Majumder, Nayim Sepay, Sachinath Bera, Rita Kundu, Michael G B Drew, Tapas Ghosh
The reaction of 2-hydroxybenzoylhydrazine (H2bh) separately with equimolar amounts of [V(IV)O(aa)2] and [V(IV)O(ba)2] in CHCl3 afforded the complexes [VO3(HL(1))2] (1) and [VO3(HL(2))2] (2) respectively in good to excellent yield ((HL(1))(2-) and (HL(2))(2-) represent respectively the dianionic form of 2-hydroxybenzoylhydrazones of acetylacetone (H3L(1)) and benzoylacetone (H3L(2)) (general abbreviation H3L)). From X-ray structure analysis, the V(V)-O-V(V) angle was found to be ∼115° and 180° in 1 and 2 respectively...
November 15, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29122714/diethanolamine-modified-pectin-based-core-shell-composites-as-dual-working-gastroretentive-drug-cargo
#5
Hriday Bera, Sanoj Kumar
The current study aimed at developing diethonolamine-modified high-methoxyl pectin (DMP)-alginate (ALG) based core-shell composites for controlled intragastric delivery of metformin HCl (MFM) by combined approach of floating and bioadhesion. DMP with degree of amidation of 48.72% was initially accomplished and characterized by FTIR, DSC and XRD analyses. MFM-loaded core matrices were then fabricated by ionotropic gelation technique employing zinc acetate as cross-linker. The core matrices were further coated by fenugreek gum (FG)-ALG gel membrane via diffusion-controlled interfacial complexation method...
November 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29116575/isolation-and-characterization-of-a-novel-t7-like-phage-against-aeromonas-veronii
#6
Taruna Anand, Bidhan Ch Bera, Nitin Virmani, Rajesh Kumar Vaid, Medhavi Vashisth, Bhupendra Nath Tripathi
A virulent Aeromonas veronii biovar sobria and the corresponding novel, lytic bacteriophage (VTCCBPA5) were isolated from village pond water. The phage was found to belong to family Podoviridae. PCR analysis of major capsid protein gene confirmed its classification to T7-like genus. The protein profiling by SDS-PAGE indicated the major structural protein to be ~ 45 kDa. The phage (VTCCBPA5) is host specific and is stable over a range of pH (6-10) and temperatures (4-45 °C). On the basis of restriction endonuclease analysis combined with prediction mapping, it was observed to vary significantly from previously reported podophages of Aeromonas sp...
November 7, 2017: Virus Genes
https://www.readbyqxmd.com/read/29105646/randomness-in-quantum-mechanics-philosophy-physics-and-technology
#7
Manabendra Nath Bera, Antonio Acín, Marek Kuś, Morgan W Mitchell, Maciej Lewenstein
This progress report covers recent developments in the area of quantum randomness, which is an extraordinarily interdisciplinary area that belongs not only to physics, but also to philosophy, mathematics, computer science, and technology. For this reason the article contains three parts that will be essentially devoted to different aspects of quantum randomness, and even directed, although not restricted, to various audiences: a philosophical part, a physical part, and a technological part. For these reasons the article is written on an elementary level, combining simple and non-technical descriptions with a concise review of more advanced results...
December 2017: Reports on Progress in Physics
https://www.readbyqxmd.com/read/29103691/immunogenicity-and-protective-efficacy-of-inactivated-equine-influenza-h3n8-virus-vaccine-in-murine-model
#8
Selvaraj Pavulraj, Nitin Virmani, Bidhan Chandra Bera, Alok Joshi, Taruna Anand, Meenakshi Virmani, Rajendra Singh, Raj Kumar Singh, Bhupendra Nath Tripathi
Equine influenza viruses (EIVs) are responsible for acute contagious respiratory infection in equines and the disease remains a major threat for equine population throughout the world despite vaccination strategies in place. The present study was aimed to assess the suitability of BALB/c mice as a potential small animal model for preliminary screening of EI vaccine candidates. For this, we evaluated the immunogenicity and protective efficacy of an inactivated EIV (H3N8) vaccine in BALB/c mouse model after challenge with homologous H3N8 virus (Clade 2 virus, Florida sublineage) through serology, clinical signs, gross and histopathology lesions with grading, immunohistochemistry and virus quantification...
October 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29100610/pregnancy-outcome-following-in-utero-exposure-to-azathioprine-a-french-comparative-observational-study
#9
Zayneb Alami, Marie Sara Agier, Samir Ahid, Thierry Vial, Anne Dautriche, Laurence Lagarce, Annick Toutain, Yahia Cherrah, Annie-Pierre Jonville-Bera
AIM OF THE STUDY: To evaluate whether azathioprine exposure during pregnancy increases the risk of birth defects and prematurity. METHOD: Prospective comparative observational study using the French pregnancy database TERAPPEL. To evaluate birth defects, outcomes of pregnancies exposed to azathioprine during the 1st trimester were prospectively assessed and compared to that of pregnancies exposed to another drug used for the same indications. Secondly, the rate of preterm births was compared between fetuses exposed to azathioprine at least during the third trimester and those exposed during the first trimester only...
October 6, 2017: Thérapie
https://www.readbyqxmd.com/read/29075712/correction-an-efficient-charge-separation-and-photocurrent-generation-in-the-carbon-dot-zinc-oxide-nanoparticle-composite
#10
Monoj Kumar Barman, Piyali Mitra, Rajesh Bera, Somnath Das, Amitava Pramanik, Amitava Patra
Correction for 'An efficient charge separation and photocurrent generation in the carbon dot-zinc oxide nanoparticle composite' by Monoj Kumar Barman et al., Nanoscale, 2017, 9, 6791-6799.
November 9, 2017: Nanoscale
https://www.readbyqxmd.com/read/29063630/isolation-and-characterization-of-multi-drug-resistant-leclercia-species-from-animal-clinical-case
#11
Mamta Choudhary, Binod Kumar Choudhary, Smita Bhoyar, Satyajit B Kale, S P Chaudhari, B C Bera, Ashok Jain, S B Barbuddhe
Leclercia adecarboxylata, a Gram-negative bacillus of family Enterobacteriaceae, is an uncommonly identified pathogen isolated from environmental and clinical specimens. Most of the human infections are polymicrobial and commonly occur in immunocompromised hosts, although nosocomial infections in immunocompetent hosts have been documented. Here, we describe the case of isolation of Leclercia species as polymicrobial infection from bovine suffering from respiratory distress in Chhattisgarh state of India. The isolates were identified by their phenotypes, 16S rDNA sequencing and by MALDI TOF-MS...
October 24, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/29062193/application-of-radio-frequency-based-digital-thermometer-for-real-time-monitoring-of-dairy-cattle-rectal-temperature
#12
Tridib Debnath, Santanu Bera, Suman Deb, Prasenjit Pal, Nibash Debbarma, Avijit Haldar
AIM: Dairy cattle health monitoring program becomes vital for detecting the febrile conditions to prevent the outbreak of the animal diseases as well as ensuring the fitness of the animals that are directly affecting the health of the consumers. The aim of this study was to validate real-time rectal temperature (RT) data of radio frequency based digital (RFD) thermometer with RT data of mercury bulb (MB) thermometer in dairy cattle. MATERIALS AND METHODS: Two experiments were conducted...
September 2017: Veterinary World
https://www.readbyqxmd.com/read/29050596/morphological-structural-and-functional-properties-of-starch-granules-extracted-from-the-tubers-and-seeds-of-sphenostylis-stenocarpa
#13
Paul Malumba, Lynn Doran, Wilfried Zanmenou, Sylvanus Odjo, Joseph Katanga, Christophe Blecker, François Béra
Sphenostylis stenocarpa (Hochst. ex A. Rich.) Harms, is a legume widely recognized in Africa for its edible starchy tuber and seeds. In the present morphological, structural and functional properties of starch extracted from the tubers and seeds of a same accession of this plant were characterized and compared. With smaller and more angular granules, tuber starch displayed higher resistance toward amylolysis and gelatinization than seed starch. The amylolysis of seed starch resulted in fragmented granules with typical layered structures of growth rings...
December 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29035522/cobalt-ion-promoted-redox-cascade-a-route-to-spiro-oxazine-oxazepine-derivatives-and-a-dinuclear-cobalt-iii-complex-of-an-n-1-4-naphthoquinone-o-aminophenol-derivative
#14
Sandip Mondal, Sachinath Bera, Suvendu Maity, Prasanta Ghosh
The study discloses that the redox activity of N-(1,4-naphthoquinone)-o-aminophenol derivatives (L(R)H2) containing a (phenol)-NH-(1,4-naphthoquinone) fragment is notably different from that of a (phenol)-NH-(phenol) precursor. The former is a platform for a redox cascade. L(R)H2 is redox noninnocent and exists in Cat-N-(1,4-naphthoquinone)(2-) (L(R 2-)) and SQ-N-(1,4-naphthoquinone) (L(R •-)) states in the complexes. Reactions of L(R)H2 with cobalt(II) salts in MeOH in air promote a cascade affording spiro oxazine-oxazepine derivatives ((OX)L(R)) in good yields, when R = H, Me, (t)Bu...
November 6, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29034339/a-method-for-the-production-of-large-volumes-of-waf-and-cewaf-for-dosing-mesocosms-to-understand-marine-oil-snow-formation
#15
Terry L Wade, Maya Morales-McDevitt, Gopal Bera, Dawai Shi, Stephen Sweet, Binbin Wang, Gerado Gold-Bouchot, Antonietta Quigg, Anthony H Knap
Marine oil snow (MOS) formation is a mechanism to transport oil from the ocean surface to sediments. We describe here the use of 110L mesocosms designed to mimic oceanic parameters during an oil spill including the use of chemical dispersants in order to understand the processes controlling MOS formation. These experiments were not designed to be toxicity tests but rather to illustrate mechanisms. This paper focuses on the development of protocols needed to conduct experiments under environmentally relevant conditions to examine marine snow and MOS...
October 2017: Heliyon
https://www.readbyqxmd.com/read/29016904/arabinogalactan-proteins-accumulate-in-the-cell-walls-of-searching-hyphae-of-the-stem-parasitic-plants-cuscuta-campestris-and-cuscuta-japonica
#16
Akitaka Hozumi, Subhankar Bera, Daiki Fujiwara, Takeshi Obayashi, Ryusuke Yokoyama, Kazuhiko Nishitani, Koh Aoki
Stem parasitic plants (Cuscuta spp.) develop a specialized organ called a haustorium to penetrate their hosts' stem tissues. To reach the vascular tissues of the host plant, the haustorium needs to overcome the physical barrier of the cell wall, and the parasite-host interaction via the cell wall is a critical process. However, the cell wall components responsible for the establishment of parasitic connections have not yet been identified. In this study, we investigated the spatial distribution patterns of cell wall components at a parasitic interface using parasite-host complexes of Cuscuta campestris-Arabidopsis thaliana and Cuscuta japonica-Glycine max...
November 1, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28988180/are-there-any-differences-between-different-testing-sites-a-cross-sectional-study-of-a-norwegian-low-threshold-hiv-testing-service-for-men-who-have-sex-with-men
#17
Bera Ulstein Moseng, Vegar Bjørnshagen
OBJECTIVE: To describe a Norwegian low-threshold HIV testing service targeting men who have sex with men (MSM). DESIGN AND SETTING: After the HIV testing consultation, all users of the HIV testing service were invited to answer the study questionnaire. The study setting included the sites where testing was performed, that is, the testing service's office in Oslo, cruising areas, bars/clubs and in hotels in other Norwegian cities. PARTICIPANTS: MSM users of the testing service...
October 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28972132/leucine-rich-repeat-containing-8b-lrrc8b-protein-is-associated-with-the-endoplasmic-reticulum-calcium-leak-in-hek293-cells
#18
Arijita Ghosh, Nitin Khandelwal, Arvind Kumar, Amal Kanti Bera
Leucine-rich repeat-containing 8 (LRRC8) proteins have been proposed to be originated from the combination of a channel protein pannexin, and a leucine-rich repeat (LRR) domain. Five paralogs of LRRC8, namely LRRC8A, B, C, D and E have been reported. LRRC8A has been shown to be instrumental in cell swelling. We have identified LRRC8B as a key player in cellular Ca(2+) signaling network. Overexpression of human LRRC8B in HEK293 cells reduced Ca(2+) level in the endoplasmic reticulum (ER). LRRC8B overexpressed cells exhibited lesser release of ER-Ca(2+) in response to ATP, carbachol and intracellular administration of IP3 LRRC8B knockdown cells showed slower depletion of the ER-Ca(2+) stores when sarco-endoplasmic reticulum Ca(2+)-ATPase was blocked with thapsigargin (TG), while overexpression of LRRC8B had opposite effect...
October 2, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28971196/esipt-induced-fluorescent-o-hydroxycinnamate-a-self-monitoring-phototrigger-for-prompt-image-guided-uncaging-of-alcohols
#19
Amrita Paul, Rakesh Mengji, Olive Abraham Chandy, Surajit Nandi, Manoranjan Bera, Avijit Jana, Anakuthil Anoop, N D Pradeep Singh
o-Hydroxycinnamate derivatives are well-known phototriggers for fast and direct release of alcohols and amines without proceeding through the cleavage of carbonate or carbamate linkages. Despite these unique features, o-hydroxycinnamates lack extensive applications in biological systems mainly because of their non-fluorescent nature. To overcome this limitation, we have attached a 2-(2'-hydroxyphenyl) benzothiazole (HBT) moiety, capable of rapid excited-state intramolecular proton transfer (ESIPT) to the o-hydroxycinnamate group...
October 18, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28969145/wilms-tumour-in-an-adult-a-case-report-of-an-unusual-lesion
#20
Goutam Bera, Zeenat Ara, Moumita Sengupta, Uttara Chatterjee, Madhumita Mukhopadhyay
Wilms' tumour, a renal malignancy, primarily occurs in children with a peak incidence between 2 to 5 years age group and accounts for approximately 95% of childhood renal malignancies. Though rarely, it may also occur in adults with an incidence rate of less than 0.2 per million per year. Microscopically, there is no difference between Wilms' tumour of paediatric and adult age groups. But the prognosis for adults with Wilms' tumour is thought to be worse than that for children possibly due to more aggressive clinical course in case of adult Wilms' tumour...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
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