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Sayak Ganguli, Sabdar Rahaman, Abhishek R Bera, Vineet Vishal, Shelvia Malik, K Roopalakshmi, Pankaj K Singh
This study reports the analyses of the rhizospheric microbiome of the terrestrial mangrove fern Acrostichum aureum Linn. from the Indian Sunderbans. Samples were collected using standard protocols and 16S rRNA gene V3-V4 region amplicon sequencing was performed to identify the microbial communities prevalent in the rhizosphere. A total of 1,931,252 quality checked reads were assembled into 204,818 contigs and were analysed using QIIME to reveal the abundance of Proteobacteria, Acidobacteria and Planctomycetes...
December 2017: Genomics Data
Ashwini Kumar, S C Gupta, V R Sinha
The objectives were to determine the incidence of hearing impairment in a standardized population of neonates and to determine the significance of association of epidemiological and risk factors with neonatal hearing loss. A cohort of 600 newborns was selected for study and divided into two groups-525 in 'No Risk' group and remaining 75 in 'At Risk' group. The study protocol was carried out in three steps: (a) Screening of Hearing Loss with TOAE, done from 36 h after birth to 28 days of life, (b) Re-screening of hearing loss in newborns (of 4-12 weeks of age), who were tested positive for hearing loss in the first screening, done with DPOAE, (c) Confirmation of hearing loss with BERA, in those who were tested positive in both the first and second screening...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
Krishnendu Bera, Priyanka Rani, Gaurav Kishor, Shikha Agarwal, Antresh Kumar, Durg Vijay Singh
ATP-Binding cassette (ABC) transporters play an extensive role in the translocation of diverse sets of biologically important molecules across membrane. EchnocandinB (antifungal) and EcdL protein of Aspergillus rugulosus are encoded by the same cluster of genes. Co-expression of EcdL and echinocandinB reflects tightly linked biological functions. EcdL belongs to Multidrug Resistance associated Protein (MRP) subfamily of ABC transporters with an extra transmembrane domain zero (TMD0). Complete structure of MRP subfamily comprising of TMD0 domain, at atomic resolution is not known...
September 20, 2017: Journal of Biomolecular Structure & Dynamics
Arif D Sheikh, Rahim Munir, Md Azimul Haque, Ashok Bera, Weijin Hu, Parvez Shaikh, Aram Amassian, Tom Wu
In this work, we investigated the effects of high operating temperature and thermal cycling on the photovoltaic performance of perovskite solar cells (PSCs) with a typical mesostructured (m)-TiO2-CH3NH3PbI3-xClx-spiro-OMeTAD architecture. After carrying out temperature-dependent grazing incidence wide-angle X-ray scattering (GIWAXS), in-situ X-ray diffraction (XRD) and optical absorption experiments, thermal durability of PSCs was tested by subjecting the devices to repetitive heating to 70 °C and cooling to room temperature (20 °C)...
September 18, 2017: ACS Applied Materials & Interfaces
Hriday Bera, Srilatha Mothe, Sabyasachi Maiti, Sridhar Vanga
Novel carboxymethyl fenugreek galactomannan (CFG)-gellan gum (GG)-calcium silicate (CS) composite beads were developed for controlled glimepiride (GLI) delivery. CFG having degree of carboxymethylation of 0.71 was synthesized and characterized by FTIR, DSC and XRD analyses. Subsequently, GLI-loaded hybrids were accomplished by ionotropic gelation technique employing Ca(+2)/Zn(+2)/Al(+3) ions as cross-linkers. All the formulations demonstrated excellent drug encapsulation efficiency (DEE, 48-97%) and sustained drug release behaviour (Q8h, 62-94%)...
September 12, 2017: International Journal of Biological Macromolecules
Arpita Sreemany, Melinda Kumar Bera, Anindya Sarkar
RATIONALE: The elaborate sampling and analytical protocol associated with the conventional dual-inlet isotope ratio mass spectrometry has long hindered high-resolution climate studies from biogenic accretionary carbonates. Laser-based on-line systems, in comparison, produce rapid data, but suffer from unresolvable matrix effects. It is, therefore, necessary to resolve these matrix effects to take advantage of the automated laser-based method. METHODS: Two marine bivalve shells (one aragonite and one calcite) and one fish otolith (aragonite) were first analysed using a CO2 laser ablation system attached to a continuous flow isotope ratio mass spectrometer under different experimental conditions (different laser power, sample untreated vs vacuum roasted)...
September 14, 2017: Rapid Communications in Mass Spectrometry: RCM
Goutam Bera, Amitabha Das, Sandip Chatterjee, Uttara Chatterjee
Rosette-forming glioneuronal tumor (RGNT) is a rare variety of slow growing mixed glioneuronal tumor involving primarily fourth ventricular region and occurring predominantly in young adults. We present a case of a 16-year-old boy who presented with dizziness and occipital headache. On radiological evaluation, a fairly large hypodense posterior fossa mass lesion in relation to the left side of the vermis, with a large cystic component was found. Surgical resection of the tumor was performed. Histopathological examination showed a biphasic tumor composed of bland neurocytic cells, arranged in the form of neurocytic rosettes along with glial areas resembling low-grade glioma...
April 2017: Journal of Pediatric Neurosciences
Srabanti Ghosh, Susmita Bera, Sandip Bysakh, Rajendra Nath Basu
Fabrication of multimetallic nanocatalysts with controllable composition remains a challenge for the development of low-cost electrocatalysts, and incorporating metal-based catalysts into active carbon nanoarchitectures represents an emerging strategy to improve the catalytic performance of electrocatalysts. Herein, a facile method developed for Pd nanoparticle (NP)-based multimetallic alloys incorporated on polypyrrole (Ppy) nanofibers by in situ nucleation and growth of NPs using colloidal radiolytic technique is described...
September 21, 2017: ACS Applied Materials & Interfaces
Arup Chakraborty, Ruttala Devivaraprasad, Bapi Bera, Manoj Neergat
Carbon is heat-treated with a nitrogen-containing precursor (ammonia) to obtain nitrogen-doped carbon and the composition is estimated using CHN and XPS analysis. The active site density of the carbon and nitrogen-doped carbon is quantified using 1,2-dihydroxybenzene (catechol) molecules as an adsorbate in phosphate buffer (pH 7) solution. The features of the voltammograms of the catechol-adsorbed high surface area carbon and nitrogen-doped carbon are similar to that of the polished nitrogen-grafted glassy carbon electrode (GCE) reported in the literature...
September 12, 2017: Physical Chemistry Chemical Physics: PCCP
Abhirup Mookherjee, Paramita Bera, Adinpunya Mitra, Mrinal K Maiti
Plant-associated endophytes are recognized as sources of novel bioactive molecules having diverse applications. In this study, an endophytic yeast-like fungal strain was isolated from the fruit of eggplant (Solanum melongena) and identified as Geotrichum candidum through phenotypic and genotypic characterizations. This endophytic G. candidum isolate PF005 was found to emit fruity scented volatiles. The compositional profiling of volatile organic compounds (VOCs) revealed the presence of 3-methyl-1-butanol, ethyl 3-methylbutanoate, 2-phenylethanol, isopentyl acetate, naphthalene, and isobutyl acetate in significant proportion when analyzed on a time-course basis...
September 11, 2017: Microbial Ecology
Prabhjot Kaur, Chandan Bera
The effect of alloying on the thermoelectric properties of cobaltite, CoAsS, and paracostibite, CoSbS, has been investigated in this study. Density functional theory and the Boltzmann transport equation have been applied to explore the role of phonon-phonon scattering and atomistic scattering due to alloying in phonon transport. An almost 44% reduction in thermal conductivity of CoAs0.8Sb0.2S alloy compared to pure CoAsS and an ∼15% reduction in thermal conductivity of CoAs0.2Sb0.8S compared to pure CoSbS were found...
September 20, 2017: Physical Chemistry Chemical Physics: PCCP
Barnaby C Reeves, Lazaros Andronis, Jane M Blazeby, Natalie S Blencowe, Melanie Calvert, Joanna Coast, Tim Draycott, Jenny L Donovan, Rachael Gooberman-Hill, Robert J Longman, Laura Magill, Jonathan M Mathers, Thomas D Pinkney, Chris A Rogers, Leila Rooshenas, Andrew Torrance, Nicky J Welton, Mark Woodward, Kate Ashton, Katarzyna D Bera, Gemma L Clayton, Lucy A Culliford, Jo C Dumville, Daisy Elliott, Lucy Ellis, Hannah Gould-Brown, Rhiannon C Macefield, Christel McMullan, Caroline Pope, Dimitrios Siassakos, Sean Strong, Helen Talbot
BACKGROUND: Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and underpowered. METHODS/DESIGN: This study is a feasibility and pilot trial to examine the feasibility of a full trial that will compare simple dressings, no dressing and tissue-glue as a dressing. It is examining the overall acceptability of trial participation, identifying opportunities for refinement, testing the feasibility of and validating new outcome tools to assess SSI, wound management issues and patients' wound symptom experiences...
August 29, 2017: Trials
Bidhan Ch Bera, Nitin Virmani, Naveen Kumar, Taruna Anand, S Pavulraj, Adam Rash, Debra Elton, Nicola Rash, Sandeep Bhatia, Richa Sood, Raj Kumar Singh, Bhupendra Nath Tripathi
BACKGROUND: Equine influenza is a major health problem of equines worldwide. The polymerase genes of influenza virus have key roles in virus replication, transcription, transmission between hosts and pathogenesis. Hence, the comprehensive genetic and codon usage bias of polymerase genes of equine influenza virus (EIV) were analyzed to elucidate the genetic and evolutionary relationships in a novel perspective. RESULTS: The group - specific consensus amino acid substitutions were identified in all polymerase genes of EIVs that led to divergence of EIVs into various clades...
August 23, 2017: BMC Genomics
Juliane Totzke, Deepak Gurbani, Rene Raphemot, Philip F Hughes, Khaldon Bodoor, David A Carlson, David R Loiselle, Asim K Bera, Liesl S Eibschutz, Marisha M Perkins, Amber L Eubanks, Phillip L Campbell, David A Fox, Kenneth D Westover, Timothy A J Haystead, Emily R Derbyshire
Tumor necrosis factor alpha (TNF-α) has both positive and negative roles in human disease. In certain cancers, TNF-α is infused locally to promote tumor regression, but dose-limiting inflammatory effects limit broader utility. In autoimmune disease, anti-TNF-α antibodies control inflammation in most patients, but these benefits are offset during chronic treatment. TAK1 acts as a key mediator between survival and cell death in TNF-α-mediated signaling. Here, we describe Takinib, a potent and selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer...
August 17, 2017: Cell Chemical Biology
Payel Bhattacharjee, Indrani Bera, Subhamoy Chakraborty, Nanda Ghoshal, Debasish Bhattacharyya
Snake venom L-amino acid oxidase (LAAO) exerts toxicity by inducing hemorrhage, pneumorrhagia, pulmonary edema, cardiac edema, liver cell necrosis etc. Being well conserved, inhibitors of the enzyme may be synthesized using the template of the substrate, substrate binding site and features of the catalytic site of the enzyme. Previous findings showed that aristolochic acid (AA), a major constituent of Aristolochia indica, inhibits Russell's viper venom LAAO enzyme activity since, AA interacts with DNA and causes genotoxicity, derivatives of this compound were synthesized by replacing the nitro group to reduce toxicity while retaining the inhibitory potency...
August 9, 2017: Toxicon: Official Journal of the International Society on Toxinology
F Beau-Salinas, E Bouquet, L Vrignaud, C Simon, M-S Agier, A-P Jonville-Béra
No abstract text is available yet for this article.
August 7, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
S C Yadav, Ritesh Kumar, Jaideep Kumar, Meetali Singh, B C Bera, Rajender Kumar, U Tatu, Kanika Tehri
Trypanosoma evansi is a haemo-protozoan parasite responsible for the disease surra, an economically important disease of wide range of domestic and wild animals. The present diagnostic methods using soluble antigens have inherent problems like lack of standardized and reproducible antigens, as well as ethical issues. This entails further efforts for search of defined antigenic molecules with satisfying sensitivity and specificity for sero-epidemiology of trypanosomosis. In present investigation, we have identified and purified 52-55kDa immuno-dominant protein cluster in molecular mass ranges by preparatory SDS-PAGE methods from T...
August 1, 2017: Research in Veterinary Science
Nirmalendu Biswas, Debashis Patra, Bipul Mondal, Sachinath Bera, Swarnali Acharyya, Anup Kumar Biswas, Titas Kumar Mukhopadhyay, Amrita Pal, Michael G B Drew, Tapas Ghosh
Refluxing [V(IV)O(β-diketonate)2], namely [V(IV)O(acetylacetonate)2] and [V(IV)O(benzoylacetonate)2], separately with an equivalent or excess amount of 2-aminobenzoylhydrazide (ah) in laboratory grade (LG) CH3OH in aerobic conditions afforded non-oxidovanadium(iv) and oxidovanadium(v) complexes of the type [V(IV)(L(1))2] (1), [V(V)O(L(1))(OCH3)]2 (3) and [V(IV)(L(2))2] (2), and [V(V)O(L(2))(OCH3)] (4), respectively. (L(1))(2-) and (L(2))(2-) represent the dianionic forms of 2-aminobenzoylhydrazone of acetylacetone (H2L(1)) and benzoylacetone (H2L(2)), respectively, (general abbreviation, H2L), which was formed by the in situ condensation of ah with the respective coordinated [β-diketonate] in medium-to-good yield...
August 22, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
Bidesh K Bera, Dibakar Ghosh, Punit Parmananda, G V Osipov, Syamal K Dana
We report the emergence of coexisting synchronous and asynchronous subpopulations of oscillators in one dimensional arrays of identical oscillators by applying a self-feedback control. When a self-feedback is applied to a subpopulation of the array, similar to chimera states, it splits into two/more sub-subpopulations coexisting in coherent and incoherent states for a range of self-feedback strength. By tuning the coupling between the nearest neighbors and the amount of self-feedback in the perturbed subpopulation, the size of the coherent and the incoherent sub-subpopulations in the array can be controlled, although the exact size of them is unpredictable...
July 2017: Chaos
Anupam Bera, Jayanta Ghosh, Atanu Bhattacharya
Conical intersections are now firmly established to be the key features in the excited electronic state processes of polyatomic energetic molecules. In the present work, we have explored conical intersection-mediated nonadiabatic chemical dynamics of a simple analogue nitramine molecule, dimethylnitramine (DMNA, containing one N-NO2 energetic group), and its complex with an iron atom (DMNA-Fe). For this task, we have used the ab initio multiple spawning (AIMS) dynamics simulation at the state averaged-complete active space self-consistent field(8,5)/6-31G(d) level of theory...
July 28, 2017: Journal of Chemical Physics
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