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Hypertension and diuretic

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https://www.readbyqxmd.com/read/29778133/study-of-acute-kidney-injury-on-309-hypertensive-inpatients-with-acei-arb-diuretic-treatment
#1
Qiaochao Chen, Shaofang Zhu, Jianjun Liao, Wen He
BACKGROUND: The present study investigated risk factors for acute kidney injury (AKI) in patients found to be hypertensive during hospitalization who were prescribed angiotensin converting enzyme inhibitors (ACEI)/angiotensin receptor antagonists (ARB) + diuretic combinations, in order to determine which type of diuretic or combination of diuretics used in ACE/ARB-treated patients leads to a higher risk of acute kidney injury. METHOD: Data on basic information, medical history, diagnostic information and medications prescribed were obtained from the patients' medical records...
June 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29766272/blood-pressure-is-normal-but-is-the-heart
#2
Serkan Fazlı Çelik, Cemşit Karakurt, Yılmaz Tabel, Taner Elmas, Saim Yoloğlu
BACKGROUND: There is no detailed strain analysis of cardiac functions in treated hypertensive pediatric patients. The aim of this study was to evaluate the cardio-protective effects of different drug classes in treated pediatric hypertensive patients. METHODS: Sixty non-obese-treated hypertensive patients with preserved left ventricular (LV) systolic function and 45 age-, sex-, and body mass index-matched healthy subjects underwent clinical evaluation, including 24-h ambulatory blood pressure monitoring, standard echocardiographic examination, tissue Doppler imaging, and two-dimensional Speckle Tracking Echocardiography...
May 15, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29765465/the-development-or-worsening-of-hypertension-after-transcatheter-aortic-valve-replacement-tavr-improves-short-term-and-long-term-patient-outcomes
#3
Brent J Klinkhammer, Cornelius M Dyke, Thomas A Haldis
Objectives: In patients with symptomatic aortic valve disease who are at intermediate to high risk for open surgical aortic valve replacement, transcatheter aortic valve replacement (TAVR) decreases overall mortality and improves quality of life. Hypertension (HTN) after TAVR has been associated with improved cardiac function and short-term survival but its effect on survival over 1 year is unclear. Our study aims to evaluate the effect of HTN following TAVR on short-term and long-term clinical and echocardiographic outcomes...
2018: Heart Asia
https://www.readbyqxmd.com/read/29764826/systemic-sclerosis-severe-pulmonary-arterial-hypertension-and-pericardial-effusion-at-diagnosis
#4
Patricia Moniz, Daniel Rei, Joana Rodrigues, Arturo Botella
A 51-year-old female patient with a recent hospital admission reported to the emergency room (ER) with progressive worsening of fatigue, dyspnoea and chest discomfort. She had been recently admitted and discharged with the diagnosis of pericarditis and medicated with non-steroidal anti-inflammatory drugs and diuretics. She returned to the ER with persisting symptoms. Echocardiography was repeated and showed signs of elevated right ventricular systolic pressure and a slightly increased moderate/severe pericardial effusion without signs of cardiac tamponade...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29757919/prevalence-of-ototoxic-medication-use-among-older-adults-in-beaver-dam-wisconsin
#5
Yoonmee Joo, Karen J Cruickshanks, Barbara E K Klein, Ronald Klein, OiSaeng Hong, Margaret Wallhagen
BACKGROUND AND PURPOSE: Drug-related ototoxicity may exacerbate presbycusis (age-related hearing loss); yet, few data are available on the prevalence of ototoxic medication use by older adults. The purposes of this study were to assess the impact of aging and ototoxicity on hearing loss, the prevalence of ototoxic medication use, and select characteristics associated with ototoxic medication use among older adults. METHODS: Cross-sectional analyses were conducted using select variables extracted from the baseline and 10-year follow-up assessments of the two population-based epidemiological studies to compare two points in time...
January 2018: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29751840/prevalence-of-the-potentially-inappropriate-kampo-medications-to-be-used-with-caution-among-elderly-patients-taking-any-prescribed-kampo-medications-at-a-single-centre-in-japan-a-retrospective-cross-sectional-study
#6
Junpei Komagamine, Kazuhiko Hagane
BACKGROUND: Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications. METHODS: A retrospective cross-sectional study was conducted using electronic medical records. All patients aged 65 years or older who continued visiting internal medicine physicians and were prescribed any Kampo medications from January 2015 to March 2015 were included...
May 11, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29743915/anginal-pain-and-elevated-troponin-level-despite-normal-coronary-angiography-hypertrophic-cardiomyopathy-with-severe-obstruction-due-to-vasodilator-diuretic-therapy-for-coincident-arterial-hypertension
#7
Adam Gębka, Renata Rajtar-Salwa, Rafał Hładij, Paweł Petkow Dimitrow
No abstract text is available yet for this article.
2018: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/29739234/effects-of-long-and-intermediate-acting-dihydropyridine-calcium-channel-blockers-in-hypertension-a-systematic-review-and-meta-analysis-of-18-prospective-randomized-actively-controlled-trials
#8
Chaugai Sandip, Sherpa Lhamo Yangchen, Sepehry Amir, Jafarian Kerman Scott Rezza, Arima Hisatomi
BACKGROUND: Dihydropyridine calcium channel blockers are a heterogeneous group of antihypertensive drugs. Long-acting dihydropyridine agent amlodipine is widely used for monotherapy and combination therapy for hypertension in clinical practice, while intermediate-acting dihydropyridine agents have shown inconsistent results in randomized clinical trials (RCTs). METHODS AND RESULTS: A meta-analysis of 18 RCTs enrolling a total of 80,483 patients with hypertension followed for a mean of 51...
January 1, 2018: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29738355/morning-blood-pressure-surge-is-associated-independently-with-orthostatic-hypotension-in-hypertensive-patients-under-treatment
#9
Hakan Caf, Yurdaer Dönmez, Emel Çeliker Güler, Onur Kaypakli, Yahya Kemal İçen, Mevlüt Koç
OBJECTIVE: Morning blood pressure surge (MBPS) and orthostatic hypotension (OH) play a role in the occurrence of cardiovascular events. We aimed to investigate the association between MBPS and OH in hypertensive patients under treatment. PATIENTS AND METHODS: We prospectively included 297 patients (mean age: 53.8±10.7 years, male/female: 101/196) with essential hypertension. Tilt table testing was performed for the diagnosis of OH. OH was classified into three groups as initial OH (0-15 s), classical OH (15 s to 3 min), and delayed OH (3-30 min)...
May 7, 2018: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29737255/should-all-hypertensive-patients-be-screened-for-primary-aldosteronism
#10
Stelina Alkagiet, Konstantinos Tziomalos
Primary aldosteronism (PA) is not only a leading cause of secondary and resistant hypertension, but is also quite frequent in unselected hypertensive patients. Moreover, PA is associated with increased cardiovascular risk, which is disproportionate to BP levels. In addition, timely diagnosis of PA and prompt initiation of treatment attenuates this increased risk. On the other hand, there are limited data regarding the usefulness of screening for PA in all asymptomatic or normokalemic hypertensive patients. More importantly, until now, no well-organized, large-scale, prospective, randomized controlled trial has proved the effectiveness of screening for PA for improving clinical outcome...
May 7, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29723931/photosensitizing-antihypertensive-drug-use-and-risk-of-cutaneous-squamous-cell-carcinoma
#11
K A Su, L A Habel, N S Achacoso, G D Friedman, M M Asgari
BACKGROUND: Many antihypertensive drugs (ADs) are photosensitizing, heightening reactivity of the skin to sunlight. Photosensitizing ADs have been associated with lip cancer, but whether they impact cutaneous squamous cell carcinoma (cSCC) risk is unknown. OBJECTIVES: To examine the association between AD use and cSCC risk among a cohort of non-Hispanic whites with hypertension enrolled in a comprehensive integrated healthcare delivery system in northern California (n=28,357)...
May 3, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29721584/-therapy-resistant-and-therapy-refractory-arterial-hypertension
#12
M Wallbach, M J Koziolek
Therapy-resistant and therapy-refractory arterial hypertension differ in prevalence, pathogenesis, prognosis and therapy. In both cases, a structured approach is required, with the exclusion of pseudoresistance and, subsequently, secondary hypertension. Resistant hypertension has been reported to be more responsive to intensified diuretic therapy, whereas refractory hypertension is presumed to require sympathoinhibitory therapy. Once the general measures and the drug-based step-up therapy have been exhausted, interventional procedures are available...
May 2, 2018: Der Internist
https://www.readbyqxmd.com/read/29713053/first-line-renin-angiotensin-system-inhibitors-vs-other-first-line-antihypertensive-drug-classes-in-hypertensive-patients-with-type-2-diabetes-mellitus
#13
Ganmi Wang, Yujie Chen, Liangjin Li, Wenlu Tang, James M Wright
First-line renin-angiotensin system (RAS) inhibitors are recommended for diabetic patients because of their potential nephron-protective properties. For hypertensive patients with type 2 diabetes mellitus, little is known about first-line RAS inhibitors vs. other first-line antihypertensive agents in terms of cardiovascular outcomes. We performed a meta-analysis of randomized controlled trials (RCTs) to assess the comparative efficacy of first-line RAS inhibitors vs. other first-line antihypertensive drug classes in hypertensive patients with type 2 diabetes mellitus...
May 1, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29713047/cardiovascular-morbidity-of-severe-resistant-hypertension-among-treated-uncontrolled-hypertensives-a-4-year-follow-up-study
#14
Alexandros Kasiakogias, Costas Tsioufis, Kyriakos Dimitriadis, Dimitrios Konstantinidis, Areti Koumelli, Ioannis Leontsinis, Eirini Andrikou, Nikos Vogiatzakis, Smaragdi Marinaki, Dimitrios Petras, Christos Fragoulis, Konstantinos Konstantinou, Vasilios Papademetriou, Dimitrios Tousoulis
Data regarding the prognosis of resistant hypertension (RHTN) with respect to its severity is limited. We investigated the cardiovascular risk of severe RHTN in a prospective observational study. A cohort of 1700 hypertensive patient with treated uncontrolled HTN was followed for a mean period of 3.6 ± 1.8 years. At baseline, standard clinical and laboratory workup was performed, including testing for secondary causes of RHT where applicable. Three groups were identified depending on presence of RHTN (office-based uncontrolled HTN under at least three drugs including a diuretic) and levels of office systolic blood pressure (BP): 1187 patients (70%) without RHTN, 313 (18%) with not-severe RHTN (systolic BP < 160 mmHg) and 200 (12%) with severe RHTN (systolic BP ≥ 160 mmHg)...
May 1, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29704920/hypertension-in-patients-with-type-2-diabetes-mellitus-targets-and-management
#15
REVIEW
Dimitra I Pavlou, Stavroula Α Paschou, Panagiotis Anagnostis, Michael Spartalis, Eleftherios Spartalis, Andromachi Vryonidou, Nicholas Tentolouris, Gerasimos Siasos
Two-thirds of patients with type 2 diabetes mellitus (T2DM) have arterial hypertension. Hypertension increases the incidence of both micro- and macrovascular complications in these patients, while the co-existence of these two major risk factors leads to a four-fold increased risk for cardiovascular disease (CVD) compared with normotensive non-diabetic controls. The aim of this article is to comprehensively review the literature and present updated information on targets for blood pressure (BP) and on the management of hypertension in patients with T2DM...
June 2018: Maturitas
https://www.readbyqxmd.com/read/29698719/serum-chloride-levels-track-with-survival-in-patients-with-pulmonary-arterial-hypertension
#16
Tawfeq Naal, Batool Abuhalimeh, Ghaleb Khirfan, Raed A Dweik, W H Wilson Tang, Adriano R Tonelli
BACKGROUND: Serum chloride is an important homeostatic biomarker in left heart failure, with significant prognostic implications. The impact of serum chloride in the long-term survival of pulmonary arterial hypertension (PAH) patients is unknown. We tested whether serum chloride levels are associated with long-term survival in PAH patients. METHODS: We included patients with idiopathic or heritable PAH who had a basic metabolic panel performed at the time of their diagnostic right heart catheterization...
April 23, 2018: Chest
https://www.readbyqxmd.com/read/29686438/frequency-and-associations-of-chronic-kidney-disease-among-gout-patients-from-a-university-teaching-hospital-in-nigeria
#17
Akpabio Akanimo Akpabio, Pam Stephen Dung-Gwom, Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo
Objectives: To highlight common precipitants and co-morbidities of gout in Nigerians; determine the frequency of chronic kidney disease (CKD) in Nigerian gout patients, as well as identify significant associations of CKD in gout patients. Material and methods: Retrospective cross-sectional study of gout cases seen at the Rheumatology Clinic of the Lagos State University Teaching Hospital over five years from January 2011 to December 2015. Gout was diagnosed using the 1977 American Rheumatism Association (ARA) criteria...
2018: Reumatologia
https://www.readbyqxmd.com/read/29683884/visit-to-visit-blood-pressure-variation-is-associated-with-outcomes-in-a-u-shaped-fashion-in-patients-with-myocardial-infarction-complicated-with-systolic-dysfunction-and-or-heart-failure-findings-from-the-ephesus-and-optimaal-trials
#18
João Pedro Ferreira, Kévin Duarte, Bertram Pitt, Kenneth Dickstein, John J V McMurray, Faiez Zannad, Patrick Rossignol
BACKGROUND: Visit-to-visit office blood pressure variation (BPV) has prognostic implications independent from mean BP across several populations in the cardiovascular field. The association of BPV with outcomes in patients with myocardial infarction (MI) with systolic dysfunction and/or heart failure is yet to be determined. METHODS: Two independent cohorts were assessed: the EPHESUS and the OPTIMAAL trials with a total of more than 12 000 patients. The primary outcome was all-cause death...
April 21, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29683249/hypertension-control-after-an-initial-cardiac-event-among-medicare-patients-with-diabetes-mellitus-a-multidisciplinary-group-practice-observational-study
#19
Ashish Chaddha, Maureen A Smith, Mari Palta, Heather M Johnson
Patients with diabetes mellitus and cardiovascular disease have a high risk of mortality and/or recurrent cardiovascular events. Hypertension control is critical for secondary prevention of cardiovascular events. The objective was to determine rates and predictors of achieving hypertension control among Medicare patients with diabetes and uncontrolled hypertension after hospital discharge for an initial cardiac event. A retrospective analysis of linked electronic health record and Medicare data was performed...
April 23, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29676870/-which-place-for-thiazide-and-thiazide-like-diuretics-in-patients-with-type-2-diabetes
#20
A J Scheen, J M Krzesinski
The use of thiazides as antihypertensive agents has been challenged because associated metabolic adverse events, including new-onset diabetes. However, these metabolic disturbances are less marked with low-dose of hydrochlorothiazide and with thiazide-like diuretics such as chlorthalidone and indapamide. In post hoc analyses of subgroups of patients with hypertension and type 2 diabetes, thiazide(-like) diuretics resulted in a significant reduction in cardiovascular events, all-cause mortality and hospitalization for heart failure compared to placebo...
April 2018: Revue Médicale de Liège
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