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https://www.readbyqxmd.com/read/29036941/breast-implant-associated-anaplastic-large-cell-lymphoma-in-a-transgender-woman
#1
Mintsje de Boer, Wouter B van der Sluis, Jan P de Boer, Lucy I H Overbeek, Flora E van Leeuwen, Hinne A Rakhorst, René R W J van der Hulst, Nathalie J Hijmering, Mark-Bram Bouman, Daphne de Jong
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is a rare but serious complication in patients with breast implants, Patients are at risk of BIA-ALCL whether they receive breast implants for cosmetic reasons or for reconstructive purposes after surgery for breast cancer or prophylactic mastectomy. During the past decade, an increased number of reports have addressed BIA-ALCL. Herein, we describe BIA-ALCL in a transgender woman. The patient received breast implants as part of her gender transition and was diagnosed with BIA-ALCL 20 years later...
September 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29035643/role-of-bone-modifying-agents-in-metastatic-breast-cancer-an-american-society-of-clinical-oncology-cancer-care-ontario-focused-guideline-update
#2
Catherine Van Poznak, Mark R Somerfield, William E Barlow, J Sybil Biermann, Linda D Bosserman, Mark J Clemons, Sukhbinder K Dhesy-Thind, Melissa S Dillmon, Andrea Eisen, Elizabeth S Frank, Reshma Jagsi, Rachel Jimenez, Richard L Theriault, Theodore A Vandenberg, Gary C Yee, Beverly Moy
Purpose To update, in collaboration with Cancer Care Ontario (CCO), key recommendations of the American Society of Clinical Oncology (ASCO) guideline on the role of bone-modifying agents (BMAs) in metastatic breast cancer. This focused update addressed the new data on intervals between dosing and the role of BMAs in control of bone pain. Methods A joint ASCO-CCO Update Committee conducted targeted systematic literature reviews to identify relevant studies. Results The Update Committee reviewed three phase III noninferiority trials of dosing intervals, one systematic review and meta-analysis of studies of de-escalation of BMAs, and two randomized trials of BMAs in control of pain secondary to bone metastases...
October 16, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29033716/transdermal-fentanyl-as-an-adjuvant-to-paravertebral-block-for-pain-control-after-breast-cancer-surgery-a-randomized-double-blind-controlled-trial
#3
Ahmed H Bakeer, Nasr M Abdallah
OBJECTIVE: The aim of this study is to investigate the effect of transdermal fentanyl (TDF) as an adjuvant to paravertebral block (PVB) for pain control after breast cancer surgery. PATIENTS AND METHODS: This randomized, double-blind trial included fifty females with breast cancer scheduled for surgery. They were randomly allocated into one of two equal groups. The TDF group used transdermal fentanyl patches (TFPs) 25 μg/h applied 10 h preoperative then PVB with 20 mL of bupivacaine 0...
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28985783/-fencing-for-promoting-health-after-breast-cancer
#4
REVIEW
Marie-France Leroy
Physical activity is recommended after breast cancer surgery. Fencing is a sport that is well suited to combatting fatigue, pain and reduced arm mobility. A healthcare executive, herself a fencer, puts the benefits of this sport into perspective, both physically and psychologically.
October 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28982848/lipofilling-outcomes-mimicking-breast-cancer-recurrence-case-report-and-update-of-the-literature
#5
REVIEW
Silvia Gigli, Maria Ida Amabile, Francesca DI Pastena, Alessandro DE Luca, Caterina Gulia, Lucia Manganaro, Massimo Monti, Laura Ballesio
Breast lipofilling uses autologous fat grafting to correct breast defects after radical or conservative surgery. After early concerns regarding its application in reconstruction after breast cancer (BC), in 2009 the American Society of Plastic Surgeons formed a task force to assess the indications, safety and efficacy of autologous fat grafting. We report the case of a woman who came to our attention for a painful swelling of the left breast. She had undergone breast-conserving therapy for BC, followed by lipofilling...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28953631/thoracic-paravertebral-regional-anesthesia-for-pain-relief-in-patients-with-breast-cancer-surgery
#6
RANDOMIZED CONTROLLED TRIAL
Lian-Jin Jin, Li-Yong Wen, Yan-Li Zhang, Gang Li, Ping Sun, Xuan Zhou
BACKGROUND: The present study aimed to assess the efficacy and safety of thoracic paravertebral regional anesthesia (TPVBRA) in patients with breast cancer surgery. METHODS: In total, 72 patients undergoing breast cancer surgery were randomly divided into an intervention group and a control group; each group contained 36 subjects. Both groups received TPVBRA with 20 mL 0.25% bupivacaine. In addition, subjects in the intervention group also received an additional 1 μg/kg dexmedetomidine...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28945634/influence-of-menopausal-status-on-the-symptom-experience-of-women-before-breast-cancer-surgery
#7
Melissa Mazor, Janine K Cataldo, Kathryn Lee, Anand Dhruva, Steven M Paul, Betty J Smoot, Laura B Dunn, Jon D Levine, Judy Mastick, Yvette P Conley, Christine Miaskowski
BACKGROUND: Breast cancer treatments can change women's hormonal milieu and alter their symptom experience. Little is known about associations between menopausal status and menopausal symptoms in women with breast cancer before surgery. OBJECTIVE: The purpose of this study was to evaluate for differences in occurrence, severity, and distress of symptoms between premenopausal and postmenopausal women before breast cancer surgery. METHODS: A total of 312 women with breast cancer completed the Menopausal Symptoms Scale, a self-report measure that evaluated the occurrence, severity, and distress of 46 common symptoms associated with menopause...
September 23, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28943914/metastatic-gastric-cancer-from-breast-carcinoma-a-report-of-78-cases
#8
Liang Xu, Shujing Liang, Ningning Yan, Le Zhang, Hailiang Gu, Xiaochun Fei, Yingchun Xu, Fengchun Zhang
The metastatic spread of breast carcinoma to the stomach is rare. There are a small number of previous studies that report metastases from the breast to the stomach and these provide limited information regarding this infrequent event. Consequently, the clinicopathological features, clinical outcomes and the optimal treatment for these patients remain to be elucidated. In the present study, 78 cases of gastric metastases from breast cancer, including the current case, were identified from previous studies between 1960 and 2015...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28924368/the-effects-of-perioperative-anesthesia-and-analgesia-on-immune-function-in-patients-undergoing-breast-cancer-resection-a-prospective-randomized-study
#9
Jin Sun Cho, Mi-Hyang Lee, Seung Il Kim, Seho Park, Hyung Seok Park, Ein Oh, Jong Ho Lee, Bon-Nyeo Koo
Introduction: Perioperative anesthesia and analgesia exacerbate immunosuppression in immunocompromised cancer patients. The natural killer (NK) cell is a critical part of anti-tumor immunity. We compared the effects of two different anesthesia and analgesia methods on the NK cell cytotoxicity (NKCC) in patients undergoing breast cancer surgery. Methods: Fifty patients undergoing breast cancer resection were randomly assigned to receive propofol-remifentanil anesthesia with postoperative ketorolac analgesia (Propofol-ketorolac groups) or sevoflurane-remifentanil anesthesia with postoperative fentanyl analgesia (Sevoflurane-fentanyl group)...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28918579/analysis-of-undesirable-sequelae-of-sentinel-node-surgery-in-breast-cancer-patients-a-prospective-cohort-study
#10
Dominika Kozak, Iwona Głowacka-Mrotek, Tomasz Nowikiewicz, Zygmunt Siedlecki, Wojciech Hagner, Magdalena Sowa, Wojciech Zegarski
Use of sentinel lymph node biopsy limits the frequency and severity of sequelae of surgical treatment. However, the procedure itself may not be completely free of complications. The goal of this work was to analyze prospectively the occurrence of undesirable sequelae in patients undergoing sentinel lymph node biopsy as an isolated intervention in the axillary fossa. This prospective observational study was conducted on a group of 104 women. Patients were examined on five occasions: one day before the procedure, one day after the procedure, one month, three months, and six months after the procedure...
September 16, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28918186/health-related-quality-of-life-in-melanoma-patients-impact-of-melanoma-related-limb-lymphoedema
#11
Caroline A Gjorup, Mogens Groenvold, Helle W Hendel, Karin Dahlstroem, Krzysztof T Drzewiecki, Tobias W Klausen, Lisbet R Hölmich
AIM: To explore health-related quality of life (HRQoL) in recurrence-free melanoma patients, with a focus on the association between melanoma-related limb lymphoedema and HRQoL. METHODS: HRQoL was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the breast cancer module (EORTC QLQ-BR23) subscales body image and future perspective, the Functional Assessment for Cancer Therapy-General subscale social/family well-being and the Hospital Anxiety and Depression Scale...
November 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28916957/perspectives-of-women-considering-bilateral-prophylactic-mastectomy-and-their-peers-towards-a-telephone-based-peer-support-intervention
#12
D St-Pierre, K Bouchard, L Gauthier, J Chiquette, Michel Dorval
Prophylactic mastectomy is an effective strategy to reduce the risk of breast cancer for women carrying a BRCA1/2 germline mutation. This decision is complex and may raise various concerns. Women considering this surgery have reported their desire to discuss the implications of this procedure with women who have undergone prophylactic mastectomy. We conducted a qualitative study to describe the topics covered during a telephone-based peer support intervention between women considering prophylactic mastectomy (recipients) and women who had undergone this surgery (peers), and to explore their perspectives regarding the intervention...
September 15, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28870961/the-local-recurrence-of-breast-cancer-with-squamous-metaplasia-and-obvious-histological-heterogeneity
#13
Nami Yamashita, Eriko Tokunaga, Hidetaka Yamamoto, Chikako Shimizu, Kenji Taketani, Yuka Inoue, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara
CASE REPORT: We herein report a case of local recurrence of breast cancer with squamous metaplasia and obvious intratumoral and intertumoral heterogeneity. A 39-year-old female patient was diagnosed with T3N2M0 stage IIIB right breast cancer and underwent right total mastectomy and axillar lymph node dissection. At four years after surgery, she became aware of chest wall pain and diagnostic imaging revealed recurrence in the lung, right thoracic wall and sternum. The recurrent lesions remained stable for 18 months with endocrine therapy...
September 2017: Anticancer Research
https://www.readbyqxmd.com/read/28868021/a-case-of-recurrent-breast-cancer-identified-by-pulmonary-tumor-thrombotic-microangiopathy
#14
Tomomi Abe, Ippei Fukada, Taro Shiga, Hidetomo Morizono, Koichi Ikebata, Tomoko Shibayama, Kokoro Kobayashi, Takuji Iwase, Shinji Ohno, Yoshinori Ito
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare, cancer-related, pulmonary complication that causes hypoxia and pulmonary hypertension. We report on a 42-year-old woman who was diagnosed with recurrent breast cancer that was detected due to the presence of PTTM. Eleven months after surgery for heterochronous bilateral cancer of the left breast, she developed progressive dyspnea but computerized tomography showed no pulmonary thromboembolism, and a transthoracic echocardiography revealed mild pulmonary hypertension...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28862111/how-can-we-improve-education-of-breast-surgeons-across-europe
#15
Agnieszka Kolacinska
The proposed global curriculum developed by the American Society of Surgical Oncology (SSO) and the European Society of Surgical Oncology (ESSO) and the textbook: provides a state-of- the- art of breast cancer surgery, complements the syllabus and curriculum of the Union Europeenne des Medecins Specialistes (UEMS) examination in breast surgery/ European Board of Surgery Qualification in Breast Surgery (EBSQinBS) administered by ESSO (1) Knowledge and understanding of the principles of breast cancer incidence, aetiology, risk factors, genetics, premalignant and high-risk lesions, pathology, prognostic and predictive factors, risk prediction models, screening, diagnosis and imaging, breast cancer, oncoplastic, reconstructive breast surgery, axillary surgery and future perspective for this, radiation therapy, neoadjuvant and adjuvant systemic treatment- endocrine-, immuno- and chemotherapy, side effects and toxicities of treatment, locoregional recurrence, follow-up, locally advanced breast cancer, metastatic breast cancer, breast cancer in young and elderly patients, survivor issues, lymphedema, palliative care, chroni pain, body image and sexuality, fertility issues, cognitive functions, etc...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28861642/chronic-pain-and-other-symptoms-among-breast-cancer-survivors-prevalence-predictors-and-effects-on-quality-of-life
#16
Rola Hamood, Hatem Hamood, Ilya Merhasin, Lital Keinan-Boker
PURPOSE: To investigate prevalence and risk factors associated with self-reported chronic pain, and other symptoms related to breast cancer or its treatment among breast cancer survivors (BCS). METHODS: A cross-sectional study of a random sample of 410 female BCS, members of "Leumit" healthcare fund, diagnosed with primary nonmetastatic invasive breast cancer in the years 2002-2012. The study questionnaire included questions on health-related quality of life, pain symptoms, and was completed by all women contacted...
August 31, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28816143/radiation-therapy-versus-no-radiation-therapy-to-the-neo-breast-following-skin-sparing-mastectomy-and-immediate-autologous-free-flap-reconstruction-for-breast-cancer-patient-reported-and-surgical-outcomes-at-1-year-a-mastectomy-reconstruction-outcomes-consortium
#17
MULTICENTER STUDY
Andrew L Cooke, Julian Diaz-Abele, Tom Hayakawa, Ed Buchel, Kimberly Dalke, Pascal Lambert
PURPOSE: To determine whether adjuvant radiation therapy (RT) is associated with adverse patient-reported outcomes and surgical complications 1 year after skin-sparing mastectomy and immediate autologous free flap reconstruction for breast cancer. METHODS AND MATERIALS: We compared 24 domains of patient-reported outcome measures 1 year after autologous reconstruction between patients who received adjuvant RT and those who did not. A total of 125 patients who underwent surgery between 2012 and 2015 at our institution were included from the Mastectomy Reconstruction Outcomes Consortium study database...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28799015/risk-factors-of-pain-in-breast-cancer-survivors-a-systematic-review-and-meta-analysis
#18
REVIEW
Laurence Leysen, David Beckwée, Jo Nijs, Roselien Pas, Thomas Bilterys, Sofie Vermeir, Nele Adriaenssens
BACKGROUND: Breast cancer remains the number 1 lethal malignancy in women. With rising incidence and decreased mortality, the number of breast cancer survivors has increased. Consequently, sequelae, such as pain, are becoming more important. PURPOSE: The purpose of this study was to identify risk factors for the development of pain in breast cancer survivors. METHODS: PubMed and Web of Science were systematically screened for studies encompassing risk factors for the development of pain in breast cancer survivors...
August 10, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28797856/neuropathic-pain-after-breast-cancer-treatment-characterization-and-risk-factors
#19
Susana Pereira, Filipa Fontes, Teresa Sonin, Teresa Dias, Maria Fragoso, José Castro-Lopes, Nuno Lunet
CONTEXT: Neuropathic pain (NP) may be an important contributor to the morbidity burden of breast cancer. OBJECTIVES: We aimed to quantify the incidence of NP in the first year after diagnosis of breast cancer, and to identify its main determinants. METHODS: We performed a prospective cohort study including 506 patients with incident breast cancer, recruited at the Portuguese Institute of Oncology of Porto, and followed for one year; patients with incident NP were additionally evaluated when this condition was diagnosed and after six months, to identify chronic NP...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28764974/associations-between-genetic-and-epigenetic-variations-in-cytokine-genes-and-mild-persistent-breast-pain-in-women-following-breast-cancer-surgery
#20
Kimberly E Stephens, Jon D Levine, Bradley E Aouizerat, Steven M Paul, Gary Abrams, Yvette P Conley, Christine Miaskowski
Persistent pain following breast cancer surgery is a significant problem. Both inherited and acquired mechanisms of inflammation appear to play a role in the development and maintenance of persistent pain. In this longitudinal study, growth mixture modeling was used to identify persistent breast pain phenotypes based on pain assessments obtained prior to and monthly for 6months following breast cancer surgery. Associations between the "no pain" and "mild pain" phenotypes and single nucleotide polymorphisms (SNPs) spanning 15 cytokine genes were evaluated...
July 29, 2017: Cytokine
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