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https://www.readbyqxmd.com/read/29036935/laser-powder-cladding-of-ti-6al-4v-%C3%AE-%C3%AE-alloy
#1
Samar Reda Al-Sayed Ali, Abdel Hamid Ahmed Hussein, Adel Abdel Menam Saleh Nofal, Salah Elden Ibrahim Hasseb Elnaby, Haytham Abdelrafea Elgazzar, Hassan Abdel Sabour
Laser cladding process was performed on a commercial Ti-6Al-4V (α + β) titanium alloy by means of tungsten carbide-nickel based alloy powder blend. Nd:YAG laser with a 2.2-KW continuous wave was used with coaxial jet nozzle coupled with a standard powder feeding system. Four-track deposition of a blended powder consisting of 60 wt % tungsten carbide (WC) and 40 wt % NiCrBSi was successfully made on the alloy. The high content of the hard WC particles is intended to enhance the abrasion resistance of the titanium alloy...
October 15, 2017: Materials
https://www.readbyqxmd.com/read/29036907/a-functional-interplay-between-igf-1-and-adiponectin
#2
REVIEW
Stefania Orrù, Ersilia Nigro, Annalisa Mandola, Andreina Alfieri, Pasqualina Buono, Aurora Daniele, Annamaria Mancini, Esther Imperlini
A functional relationship is suggested between two well-known protein hormones, insulin-like growth factor 1 (IGF-1) and adiponectin. In the last two decades in fact, different experimental evidence has indicated a non-random link between them. Here, we describe briefly the IGF-1 and adiponectin systems, and we then focus on their putative interplay in relation to several pathological conditions, including obesity, diabetes, insulin resistance, cardiovascular disease, and cancer. Although the existing studies are hardly comparable, they definitely indicate a functional connection between these two protein hormones...
October 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29036141/gloss-evaluation-from-soft-and-hard-metrologies
#3
Zihao Wang, Lihao Xu, Yu Hu, Fereshteh Mirjalili, Ming Ronnier Luo
Recent advances in bidirectional reflectance distribution function (BRDF) acquisitions have provided a novel approach for appearance measurement and analysis. In particular, since gloss appearance is dependent on the directional reflective properties of surfaces, it is reasonable to leverage the BRDF for gloss evaluation. In this paper, we investigate gloss appearance from both soft metrology and hard metrology. A psychophysical experiment was conducted for the gloss assessment of 47 neutral-color samples. In the evaluation of gloss perception from gloss meter measurements, we report several ambiguous correspondences in the medium gloss range...
September 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29036109/transparency-in-stereopsis-parallel-encoding-of-overlapping-depth-planes
#4
Adam Reeves, David Lynch
We report that after extensive training, expert adults can accurately report the number, up to six, of transparent overlapping depth planes portrayed by brief (400 ms or 200 ms) random-element stereoscopic displays, and can well discriminate six from seven planes. Naïve subjects did poorly above three planes. Displays contained seven rows of 12 randomly located ×'s or +'s; jittering the disparities and number in each row to remove spurious cues had little effect on accuracy. Removing the central 3° of the 10° display to eliminate foveal vision hardly reduced the number of reportable planes...
August 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29035855/transovarial-persistence-of-babesia-ovata-dna-in-a-hard-tick-haemaphysalis-longicornis-in-a-semi-artificial-mouse-skin-membrane-feeding-system
#5
Rika Umemiya-Shirafuji, Takeshi Hatta, Kazuhiro Okubo, Moeko Sato, Hiroki Maeda, Aiko Kume, Naoaki Yokoyama, Ikuo Igarashi, Naotoshi Tsuji, Kozo Fujisaki, Noboru Inoue, Hiroshi Suzuki
Bovine piroplasmosis, a tick-borne protozoan disease, is a major concern for the cattle industry worldwide due to its negative effects on livestock productivity. Toward the development of novel therapeutic and vaccine approaches, tick-parasite experimental models have been established to clarify the development of parasites in the ticks and the transmission of the parasites by ticks. A novel tick-Babesia experimental infection model recently revealed the time course of Babesia ovata migration in its vector Haemaphysalis longicornis, which is a dominant tick species in Japan...
December 20, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/29035587/computer-aided-stroke-by-stroke-visualization-of-actual-and-target-power-allows-for-continuously-increasing-ramp-tests-on-wind-braked-rowing-ergometers
#6
Gunnar Treff, Kay Winkert, Katja Machus, Jürgen M Steinacker
PURPOSE: Ramp tests are continuously increasing exercise tests used for determination of maximal oxygen uptake (⩒O2max), which is identifiable by a plateau in ⩒O2despite increasing mechanical power output (LOAD). On wind-braked rowing ergometers (RowErg) it is hardly feasible to ensure a continuous increase in LOAD until test termination, because neither resistance nor stroke-frequency are externally adjustable, but depend on the rower. To enable ramp tests on rowing ergometers, we produced visual stroke-by-stroke feedback showing target and actual LOAD to the rower...
October 16, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29035570/a-median-solver-and-phylogenetic-inference-based-on-double-cut-and-join-sorting
#7
Ruofan Xia, Yu Lin, Jun Zhou, Bing Feng, Jijun Tang
Genome rearrangement is known as one of the main evolutionary mechanisms on the genomic level. Phylogenetic analysis based on rearrangement played a crucial role in biological research in the past decades, especially with the increasing availability of fully sequenced genomes. In general, phylogenetic analysis aims to solve two problems: small parsimony problem (SPP) and big parsimony problem (BPP). Maximum parsimony is a popular approach for SPP and BPP, which relies on iteratively solving an NP-hard problem, the median problem...
October 16, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29035224/efficient-local-search-for-euclidean-path-difference-median-trees
#8
Alexey Markin, Oliver Eulenstein
Synthesizing large-scale phylogenetic trees is a fundamental problem in evolutionary biology. Median tree problems have evolved as a powerful tool to reconstruct such trees. Such problems seek a median tree for a given collection of input trees under some problem-specific tree distance. There has been an increased interest in the median tree problem for the classical path-difference distance between trees. While this problem is NP-hard, standard local search heuristics have been described that are based on solving a local search problem exactly...
October 16, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/29035154/ethnographic-research-in-immigrant-specific-drug-abuse-recovery-houses
#9
Anna Pagano, Juliet P Lee, Victor García, Carlos Recarte
Access to study populations is a major concern for drug use and treatment researchers. Spaces related to drug use and treatment have varying levels of researcher accessibility based on several issues, including legality, public versus private settings, and insider/outsider status. Ethnographic research methods are indispensable for gaining and maintaining access to hidden or "hard-to-reach" populations. Here, we discuss our long-term ethnographic research on drug abuse recovery houses created by and for Latino migrants and immigrants in Northern California...
October 16, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29034911/collision-cross-sections-and-ion-structures-development-of-a-general-calculation-method-via-high-quality-ion-mobility-measurements-and-theoretical-modeling
#10
Jong Wha Lee, Kimberly L Davidson, Matthew F Bush, Hugh I Kim
Ion mobility mass spectrometry (IM-MS) has become an important tool for the structural investigation of ions in the gas phase. Accurate theoretical evaluation of ion collision cross sections (CCSs) is essential for the effective application of IM-MS in structural studies. However, current theoretical tools have limitations in accurately describing a broad range of ions from small molecules to macromolecules. Significant difficulties in developing theoretical tools for CCS calculations are associated with obtaining high-quality experimental data and molecular models...
October 16, 2017: Analyst
https://www.readbyqxmd.com/read/29034628/-screening-of-full-human-anthrax-lethal-factor-neutralizing-antibody-in-transgenic-mice
#11
Xiaolin Wang, Xiangyang Chi, Ju Liu, Weicen Liu, Shuling Liu, Shunfang Qiu, Zhonghua Wen, Pengfei Fan, Kun Liu, Xiaohong Song, Ling Fu, Jun Zhang, Changming Yu
Anthrax is a highly lethal infectious disease caused by the spore-forming bacterium Bacillus anthracis. The major virulence factor of B. anthracis consists of protective antigen (PA), lethal factor (LF) and edema factor (EF). PA binds with LF to form lethal toxin (LT), and PA binds with EF to form edema toxin (ET). Antibiotics is hard to work in advanced anthrax infections, because injuries and deaths of the infected are mainly caused by lethal toxin (LT). Thus, the therapeutic neutralizing antibody is the most effective treatment of anthrax...
November 25, 2016: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/29034386/auxeticity-enhancement-due-to-size-polydispersity-in-fcc-crystals-of-hard-core-repulsive-yukawa-particles
#12
Paweł M Pigłowski, Jakub W Narojczyk, Krzysztof W Wojciechowski, Konstantin V Tretiakov
The Poisson's ratio of the fcc hard-core repulsive Yukawa crystals with size polydispersity was determined by Monte Carlo simulations in the isothermal-isobaric ensemble. The effect of size polydispersity on the auxetic properties of Yukawa crystals has been studied. It has been found that an increase of particle size polydispersity causes a decrease of the Poisson's ratio in auxetic directions as well as appearance of a negative Poisson's ratio in formerly non-auxetic directions. A measure of auxeticity was introduced to estimate quantitatively an enhancement of auxetic properties in polydisperse Yukawa crystals...
October 16, 2017: Soft Matter
https://www.readbyqxmd.com/read/29034279/rare-and-extensive-malignant-melanoma-of-the-oral-cavity-report-of-two-cases
#13
Parviz Deyhimi, Sayed Mohammad Razavi, Shirin Shahnaseri, Saeedeh Khalesi, Solmaz Homayoni, Payam Tavakoli
Primary oral melanomas are uncommon malignant neoplasm of melanocytes origin. The most common site of oral melanoma is maxillary gingiva and hard palate. Oral mucosal melanoma exhibit a pathobiological behavior and clinical features different from cutaneous melanomas. Oral melanomas are often clinically silent which may consequently result in delayed diagnosis; thus, making the prognosis extremely poor. This case report presents clinical, histopathological and immunohistochemical features of two cases of advanced oral melanoma, one pigmented or melanotic melanoma in a 46-year-old female and another amelanotic melanoma in a 59-year-old male patient, with chief complaint of swelling in oral mucosa...
September 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29034240/dark-chocolate-opportunity-for-an-alliance-between-medical-science-and-the-food-industry
#14
Ivan M Petyaev, Yuriy K Bashmakov
Dark chocolate (DC) was originally introduced in human nutrition as a medicinal product consumable in a liquid form. Century-long efforts of food industry transformed this hardly appealing product into a valuable modern culinary delight with clear predominance of confectionery brands of DC on the market. However, current epidemiological data as well as multiple experimental and clinical observations reveal that DC consumption may have a profound effect on cardiovascular, central nervous systems, hemostasis, and lipid metabolism...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29034027/retrograde-use-of-frontrunner-catheter-in-superficial-femoral-artery-for-flushing-long-segment-occlusions-involving-distal-common-femoral-artery
#15
Nelson Chavarria, Tae-Hoon Kim, Michael Azrin, Juyong Lee
We present the case of an 81-year-old female with flush occlusion of the superficial femoral artery (SFA) and percutaneous transluminal angioplasty. Initially, the antegrade approach failed due to flush occlusion without stump. Hard, round surfaced, calcific, and eccentric plaque of the ostium of SFA was also present, which involved distal common femoral artery (CFA). Thus, we successfully used a Frontrunner catheter for retrograde reentry at the lower position of the CFA. Various treatment strategies involving Frontrunner and atherectomy devices could make percutaneous procedures possible in femoropopliteal occlusive disease, involving the CFA...
March 24, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033976/conffuse-high-confidence-fusion-gene-detection-across-tumor-entities
#16
Zhiqin Huang, David T W Jones, Yonghe Wu, Peter Lichter, Marc Zapatka
Background: Fusion genes play an important role in the tumorigenesis of many cancers. Next-generation sequencing (NGS) technologies have been successfully applied in fusion gene detection for the last several years, and a number of NGS-based tools have been developed for identifying fusion genes during this period. Most fusion gene detection tools based on RNA-seq data report a large number of candidates (mostly false positives), making it hard to prioritize candidates for experimental validation and further analysis...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29033431/diagnostic-challenge-in-pancreatic-sarcoidosis-using-endoscopic-ultrasonography
#17
Nobuaki Azemoto, Teru Kumagi, Mitsuhito Koizumi, Taira Kuroda, Hirofumi Yamanishi, Yoshinori Ohno, Yoshiki Imamura, Eiji Takeshita, Yoshiko Soga, Yoshiou Ikeda, Morikazu Onji, Yoichi Hiasa
We herein report a 55-year-old woman who presented with erythema and bilateral hilar lymphadenopathy 4 months prior to the detection of pancreatic lesions on an ultrasound. A skin biopsy showed evidence of sarcoidosis. The largest lesion in the tail of the pancreas was hypoechoic on endoscopic ultrasonography (EUS). The lesion was initially iso-enhanced on contrast enhanced-EUS (CE-EUS) but subsequently became hypoenhanced. The lesion revealed heterogeneous components of both soft and hard tissue on EUS elastography...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29033393/new-bioactive-glass-scaffolds-with-exceptional-qualities-for-bone-tissue-regeneration-response-of-osteoblasts-and-osteoclasts
#18
Tia Kowal, Natalie C Hahn, Stephanie Eider, Jutta Marzillier, Daniella Marie Fodera, Ukrit Thamma, Himanshu Jain, Matthias M Falk
Tissue regeneration is a significantly improved alternative to tissue replacement by implants. It requires porous bioscaffolds for the restoration of natural tissue rather than relying on bio-inactive, often metallic implants. Recently, we developed technology for fabricating novel, nano-macroporous bioactive 'Tailored Amorphous Multi-Porous (TAMP)' hard tissue scaffolds using a 70 mol% SiO2-30 mol% CaO model composition. The TAMP silicate scaffolds, fabricated by a modified sol-gel process, have shown excellent biocompatibility via the rapid formation of hydroxyapatite in biological fluids as well as in early tests with bone forming cells...
October 16, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/29033170/assessing-the-effect-of-mercury-pollution-on-cultured-benthic-foraminifera-community-using-morphological-and-edna-metabarcoding-approaches
#19
Fabrizio Frontalini, Mattia Greco, Letizia Di Bella, Franck Lejzerowicz, Emanuela Reo, Antonio Caruso, Claudia Cosentino, Antonella Maccotta, Giovanna Scopelliti, Maria Pia Nardelli, Maria Teresa Losada, Eric Armynot du Châtelet, Rodolfo Coccioni, Jan Pawlowski
Mercury (Hg) is a highly toxic element for living organisms and is known to bioaccumulate and biomagnify. Here, we analyze the response of benthic foraminifera communities cultured in mesocosm and exposed to different concentrations of Hg. Standard morphological analyses and environmental DNA metabarcoding show evidence that Hg pollution has detrimental effects on benthic foraminifera. The molecular analysis provides a more complete view of foraminiferal communities including the soft-walled single-chambered monothalamiids and small-sized hard-shelled rotaliids and textulariids than the morphological one...
October 13, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29033149/management-of-cervicofacial-infections-a-survey-of-current-practice-in-maxillofacial-units-in-the-uk
#20
C McDonald, A Hennedige, A Henry, B Dawoud, R Kulkarni, K Gilbert, P Kyzas, R Morrison, J A McCaul
Cervicofacial infections are common emergency presentations to maxillofacial departments in the UK, there is no consensus about their management and, in particular, the role of corticosteroids is not clear. Our aim was to find out the current practice of UK maxillofacial surgeons in managing these infections using a multicentre questionnaire study. The questionnaire was designed, piloted, and revised before distribution, and questions were asked to assess preoperative, operative, and postoperative management...
October 12, 2017: British Journal of Oral & Maxillofacial Surgery
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