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Sickness behaviour

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https://www.readbyqxmd.com/read/27884936/constances-a-general-prospective-population-based-cohort-for-occupational-and-environmental-epidemiology-cohort-profile
#1
Marcel Goldberg, Matthieu Carton, Alexis Descatha, Annette Leclerc, Yves Roquelaure, Gaëlle Santin, Marie Zins
: WHY THE COHORT WAS SET UP?: CONSTANCES is a general-purpose cohort with a focus on occupational and environmental factors. COHORT PARTICIPANTS: CONSTANCES was designed as a randomly selected sample of French adults aged 18-69 years at inception; 200 000 participants will be included. DATA COLLECTION PHASES: At enrolment, the participants are invited to complete questionnaires and to attend a health screening centre (HSC) for a health examination...
November 24, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27862626/pro-and-anti-inflammatory-cytokine-associations-with-major-depression-in-cancer-patients
#2
Madeline Li, Ekaterina Kouzmina, Megan McCusker, Danielle Rodin, Paul C Boutros, Christopher J Paige, Gary Rodin
OBJECTIVE: Cytokines may be linked to depression, although it has been challenging to demonstrate this association in cancer because of the overlap between depressive symptoms and other sickness behaviors. This study investigates the relationship between cytokines and depression in cancer patients, accounting for confounding clinical and methodological factors. METHODS: The GRID Hamilton Rating Scale for Depression and Neurotoxicity Rating Scale (NRS) for cytokine-induced sickness behaviors were administered to 61 cancer patients and 38 healthy controls...
November 15, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27810210/early-detection-of-health-and-welfare-compromises-through-automated-detection-of-behavioural-changes-in-pigs
#3
REVIEW
Stephen G Matthews, Amy L Miller, James Clapp, Thomas Plötz, Ilias Kyriazakis
Early detection of health and welfare compromises in commercial piggeries is essential for timely intervention to enhance treatment success, reduce impact on welfare, and promote sustainable pig production. Behavioural changes that precede or accompany subclinical and clinical signs may have diagnostic value. Often referred to as sickness behaviour, this encompasses changes in feeding, drinking, and elimination behaviours, social behaviours, and locomotion and posture. Such subtle changes in behaviour are not easy to quantify and require lengthy observation input by staff, which is impractical on a commercial scale...
November 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27793181/internet-based-self-help-therapy-with-fearfighter%C3%A2-versus-no-intervention-for-anxiety-disorders-in-adults-study-protocol-for-a-randomised-controlled-trial
#4
Morten Fenger, Jane Lindschou, Christian Gluud, Per Winkel, Lise Jørgensen, Sten Kruse-Blinkenberg, Marianne Lau
BACKGROUND: Internet-based self-help psychotherapy (IBT) could be an important alternative or supplement to ordinary face-to-face therapy. The findings of randomised controlled trials indicate that the effects of various IBT programmes for anxiety disorders seem better than no intervention and in some instances are equivalent to usual therapy. In Denmark, IBT is part of future treatment plans in mental health care services, but the verification level of the current clinical scientific knowledge is insufficient...
October 28, 2016: Trials
https://www.readbyqxmd.com/read/27776506/background-design-and-conceptual-model-of-the-cluster-randomized-multiple-component-workplace-study-framed-intervention-to-decrease-occupational-muscle-pain-fridom
#5
Jeanette Reffstrup Christensen, Thomas Viskum Gjelstrup Bredahl, Jenny Hadrévi, Gisela Sjøgaard, Karen Søgaard
BACKGROUND: Several RCT studies have aimed to reduce either musculoskeletal disorders, sickness presenteeism, sickness absenteeism or a combination of these among females with high physical work demands. These studies have provided evidence that workplace health promotion (WHP) interventions are effective, but long-term effects are still uncertain. These studies either lack to succeed in maintaining intervention effects or lack to document if effects are maintained past a one-year period...
October 24, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27762011/measuring-resilience-in-palliative-care-workers-using-the-situational-judgement-test-methodology
#6
Antonio Pangallo, Lara Zibarras, Fiona Patterson
OBJECTIVES: Relatively little research has been directed toward the assessment of resilience in the health care context. Given the stressors associated with the provision of health care, the present study describes the development and evaluation of a situational judgement test (SJT) designed to assess resilience in palliative care health care workers. METHODS: An SJT was developed to measure behaviours associated with resilience in a palliative care context. Next, SJT reliability and validity analyses were assessed in a sample of acute ward, hospice and community palliative care workers (n = 284)...
November 2016: Medical Education
https://www.readbyqxmd.com/read/27716317/why-hospital-physicians-attend-work-while-ill-the-spiralling-effect-of-positive-and-negative-factors
#7
Fay Giæver, Signe Lohmann-Lafrenz, Lise Tevik Løvseth
BACKGROUND: Recurrent reports from national and international studies show a persistent high prevalence of sickness presence among hospital physicians. Despite the negative consequences reported, we do not know a lot about the reasons why physicians choose to work when ill, and whether there may be some positive correlates of this behaviour that in turn may lead to the design of appropriate interventions. The aim of this study is to explore the perception and experience with sickness presenteeism among hospital physicians, and to explore possible positive and negative foundations and consequences associated with sickness presence...
October 5, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27697138/acceptance-and-commitment-group-therapy-act-g-for-health-anxiety
#8
Trine Eilenberg
Health anxiety is prevalent (5-9%) in all healthcare settings and in the general population, may have an early onset, and a poor prognosis is seen in severe cases if untreated. Research shows that health anxiety is rarely diagnosed though it causes great suffering for the individual and constitutes a substantial socio-economic burden. Studies have shown that individual cognitive behavioural therapy can relieve health anxiety, but these studies are affected by methodological problems, among others, struggling with patients declining participation, high dropout rates, and some patients not responding to the treatment...
October 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27682237/understanding-how-dogs-encourage-and-motivate-walking-cross-sectional-findings-from-reside
#9
C Westgarth, M Knuiman, H E Christian
BACKGROUND: Many people live with dogs but not all walk with them regularly. This study examines the demographic and behavioural factors that contribute towards owners reporting having a strong sense of encouragement and motivation to walk provided by their dogs, which we call 'the Lassie effect'. METHODS: Data was collected from 629 dog owners participating in the RESIDE cross-sectional survey in Perth, Western Australia. Multivariable logistic regression analyses of factors associated with two separate outcome survey items 'Dog encouragement to walk' (how often dog encouraged me to go walking in last month) and 'Dog motivation to walk' (Having a dog makes me walk more)...
September 29, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27597761/caffeic-acid-attenuates-lipopolysaccharide-induced-sickness-behaviour-and-neuroinflammation-in-mice
#10
Sanchari Basu Mallik, Jayesh Mudgal, Madhavan Nampoothiri, Susan Hall, Shailendra Anoopkumar- Dukie, Gary Grant, C Mallikarjuna Rao, Devinder Arora
Accumulating data links inflammation, oxidative stress and immune system in the pathophysiology of major depressive disorders. Sickness behaviour is a set of behavioural changes that develop during infection, eventually leading to decrease in mobility and depressed behaviour. Lipopolysaccharide (LPS) induces a depression-like state in animals that mimics sickness behaviour. Caffeic acid, a naturally occurring polyphenol, possesses antioxidant and anti-inflammatory properties. The present study was designed to explore the potential of caffeic acid against LPS-induced sickness behaviour in mice...
October 6, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27580904/immunological-processes-related-to-cognitive-impairment-in-ms
#11
REVIEW
T Berger
In this review, the immune-to-brain communication pathways are briefly summarized, with emphasis on the impact of immune cells and their mediators on learning, memory and other cognitive domains. Further, the acute response of the central nervous system to peripherally generated inflammatory stimuli - termed as sickness behaviour - is described, and the central role of microglia in this immune-to-brain crosstalk in physiological and pathological conditions is highlighted. Finally, the role and consequences of immunological processes related to cognitive impairment in multiple sclerosis are discussed...
September 2016: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27549163/community-perceptions-and-practices-of-treatment-seeking-for-childhood-pneumonia-a-mixed-methods-study-in-a-rural-district-ghana
#12
Mercy Abbey, Margaret A Chinbuah, Margaret Gyapong, L Kay Bartholomew, Bart van den Borne
BACKGROUND: The World Health Organization recommends community case management of malaria and pneumonia for reduction of under-five mortality in developing countries. Caregivers' perception and understanding of the illness influences the care a sick child receives. Studies in Ghana and elsewhere have routinely shown adequate recognition of malaria by caregivers. Similarly, evidence from Asia and some African countries have shown adequate knowledge on pneumonia. However, in Ghana, little has been documented about community awareness, knowledge, perceptions and management of childhood pneumonia particularly in the Dangme West district...
2016: BMC Public Health
https://www.readbyqxmd.com/read/27529430/exaggerated-increases-in-microglia-proliferation-brain-inflammatory-response-and-sickness-behaviour-upon-lipopolysaccharide-stimulation-in-non-obese-diabetic-mice
#13
Barry McGuiness, Sinead M Gibney, Wouter Beumer, Marjan A Versnel, Inge Sillaber, Andrew Harkin, Hemmo A Drexhage
: The non-obese diabetic (NOD) mouse, an established model for autoimmune diabetes, shows an exaggerated reaction of pancreas macrophages to inflammatory stimuli. NOD mice also display anxiety when immune-stimulated. Chronic mild brain inflammation and a pro-inflammatory microglial activation is critical in psychiatric behaviour. OBJECTIVE: To explore brain/microglial activation and behaviour in NOD mice at steady state and after systemic lipopolysaccharide (LPS) injection...
2016: Neuroimmunomodulation
https://www.readbyqxmd.com/read/27513602/variations-in-attack-behaviours-between-glossina-palpalis-gambiensis-and-g-tachinoides-in-a-gallery-forest-suggest-host-specificity
#14
E Salou, J B Rayaisse, D Kaba, V Djohan, W Yoni, I Barry, F Dofini, J Bouyer, P Solano
Tsetse flies Glossina palpalis gambiensis and G. tachinoides are among the major vectors of sleeping sickness (Human African Trypanosomiasis-HAT) and nagana (African Animal Trypanosomiasis - AAT) in West Africa. Both riparian species occur sympatrically in gallery forests of south west Burkina Faso, but little is known of their interspecies relationships although different authors think there may be some competition between them. The aim of this study was to check if sympatric species have different strategies when approaching a host...
August 11, 2016: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/27475810/ants-detect-but-do-not-discriminate-diseased-workers-within-their-nest
#15
Jean-Baptiste Leclerc, Claire Detrain
Social insects have evolved an array of individual and social behaviours that limit pathogen entrance and spread within the colony. The detection of ectoparasites or of fungal spores on a nestmate body triggers their removal by allogrooming and appears as a primary component of social prophylaxis. However, in the case of fungal infection, one may wonder whether ant workers are able to detect, discriminate and keep at bay diseased nestmates that have no spores over their cuticle but which constitute a latent sanitary risk due to post-mortem corpse sporulation...
August 2016: Die Naturwissenschaften
https://www.readbyqxmd.com/read/27466236/scissor-spinal-cord-injury-study-on-small-molecule-derived-rho-inhibition-a-clinical-study-protocol
#16
Marcel A Kopp, Thomas Liebscher, Ralf Watzlawick, Peter Martus, Stefan Laufer, Christian Blex, Ralf Schindler, Gerhard J Jungehulsing, Sven Knüppel, Martin Kreutzträger, Axel Ekkernkamp, Ulrich Dirnagl, Stephen M Strittmatter, Andreas Niedeggen, Jan M Schwab
INTRODUCTION: The approved analgesic and anti-inflammatory drugs ibuprofen and indometacin block the small GTPase RhoA, a key enzyme that impedes axonal sprouting after axonal damage. Inhibition of the Rho pathway in a central nervous system-effective manner requires higher dosages compared with orthodox cyclooxygenase-blocking effects. Preclinical studies on spinal cord injury (SCI) imply improved motor recovery after ibuprofen/indometacin-mediated Rho inhibition. This has been reassessed by a meta-analysis of the underlying experimental evidence, which indicates an overall effect size of 20...
July 26, 2016: BMJ Open
https://www.readbyqxmd.com/read/27463979/community-based-reports-of-morbidity-mortality-and-health-seeking-behaviours-in-four-monrovia-communities-during-the-west-african-ebola-epidemic
#17
Kristen E McLean, Sharon Alane Abramowitz, Jacob D Ball, Josephine Monger, Kodjo Tehoungue, Sarah Lindley McKune, Mosoka Fallah, Patricia A Omidian
The goal of this study was to assess morbidity, mortality, and health-seeking behaviours during the 2014 Ebola outbreak in Monrovia, Liberia. This study examined commonly reported symptoms of illness, pre-clinical diagnostic practices, typical healthcare-seeking strategies, and health resources available to populations, in order to identify salient needs and gaps in healthcare that would inform local emergency response efforts. Semi-structured interviews were conducted with household members in four Monrovia neighbourhoods...
July 27, 2016: Global Public Health
https://www.readbyqxmd.com/read/27458105/a-global-measure-of-sickness-behaviour-development-of-the-sickness-questionnaire
#18
Anna Andreasson, Rikard K Wicksell, Karin Lodin, Bianka Karshikoff, John Axelsson, Mats Lekander
Symptoms after inflammatory activation, so-called sickness behaviour, overlap with trans-diagnostic complaints. As no self-report questionnaire to assess sickness behaviour exists, we aimed to develop such an instrument, the Sickness Questionnaire. Items responsive to experimentally induced inflammatory activation (randomized double-blind study endotoxin (0.6 ng/kg) versus placebo, n = 52) were selected and the statistical properties were examined in 172 primary care patients. A principal component analysis indicated a one-factor solution (Cronbach's alpha = ...
July 24, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27412286/calling-in-sick-impacts-of-fever-on-intra-urban-human-mobility
#19
T Alex Perkins, Valerie A Paz-Soldan, Steven T Stoddard, Amy C Morrison, Brett M Forshey, Kanya C Long, Eric S Halsey, Tadeusz J Kochel, John P Elder, Uriel Kitron, Thomas W Scott, Gonzalo M Vazquez-Prokopec
Pathogens inflict a wide variety of disease manifestations on their hosts, yet the impacts of disease on the behaviour of infected hosts are rarely studied empirically and are seldom accounted for in mathematical models of transmission dynamics. We explored the potential impacts of one of the most common disease manifestations, fever, on a key determinant of pathogen transmission, host mobility, in residents of the Amazonian city of Iquitos, Peru. We did so by comparing two groups of febrile individuals (dengue-positive and dengue-negative) with an afebrile control group...
July 13, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27371259/integrated-community-case-management-and-community-based-health-planning-and-services-a-cross-sectional-study-on-the-effectiveness-of-the-national-implementation-for-the-treatment-of-malaria-diarrhoea-and-pneumonia
#20
Blanca Escribano Ferrer, Jayne Webster, Jane Bruce, Solomon A Narh-Bana, Clement T Narh, Naa-KorKor Allotey, Roland Glover, Constance Bart-Plange, Isabella Sagoe-Moses, Keziah Malm, Margaret Gyapong
BACKGROUND: Ghana has developed two main community-based strategies that aim to increase access to quality treatment for malaria, diarrhoea and pneumonia: the Home-based Care (HBC) and the Community-based Health Planning and Services (CHPS). The objective was to assess the effectiveness of HBC and CHPS on utilization, appropriate treatment given and users' satisfaction for the treatment of malaria, diarrhoea and pneumonia. METHODS: A household survey was conducted 2 and 8 years after implementation of HBC in the Volta and Northern Regions of Ghana, respectively...
2016: Malaria Journal
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