keyword
MENU ▼
Read by QxMD icon Read
search

Evaluation of male infertility

keyword
https://www.readbyqxmd.com/read/29777228/effects-of-clomiphene-citrate-on-male-obesity-associated-hypogonadism-a-randomized-double-blind-placebo-controlled-study
#1
Andressa Heimbecher Soares, Nidia Celeste Horie, Lucas Augusto Piccinin Chiang, Bruno Caramelli, Mariana Gomes Matheus, Alexandre Holthausen Campos, Luciana Cavalheiro Marti, Fernanda Agostini Rocha, Marcio C Mancini, Elaine Maria Frade Costa, Cintia Cercato
BACKGROUND: Obesity causes secondary hypogonadism (HG) in men. Standard testosterone (T) replacement therapy improves metabolic parameters but leads to infertility. OBJECTIVE: To evaluate clomiphene citrate (CC) treatment of adult men with male obesity-associated secondary hypogonadism (MOSH). DESIGN: Single-center, randomized, double-blind, placebo-controlled trial. PARTICIPANTS: Seventy-eight men aged 36.5 ± 7...
May 17, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29774489/the-role-of-lifestyle-in-male-infertility-diet-physical-activity-and-body-habitus
#2
REVIEW
Russell P Hayden, Ryan Flannigan, Peter N Schlegel
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29770466/comparative-evaluation-of-the-effects-of-withania-somnifera-with-pentoxifylline-on-the-sperm-parameters-in-idiopathic-male-infertility-a-triple-blind-randomised-clinical-trial
#3
R Nasimi Doost Azgomi, H Nazemiyeh, H Sadeghi Bazargani, S M B Fazljou, F Nejatbakhsh, A Moini Jazani, Y Ahmadi AsrBadr, A Zomorrodi
In this triple-blind randomised clinical trial, we compared the effects of Withania somnifera and pentoxifylline on the sperm parameters in idiopathic male infertility. One hundred infertile male patients were randomly allocated into either W. somnifera or pentoxifylline groups. Patients in the herbal group received six capsules containing 5 g/daily of W. somnifera root, and subjects in the pentoxifylline group received six capsules containing 800 mg/daily of pentoxifylline and placebo for 90 days. Sperm parameters were analysed at the beginning and end of the study...
May 16, 2018: Andrologia
https://www.readbyqxmd.com/read/29766151/the-effect-of-supernatant-product-of-adipose-tissue-derived-mesenchymal-stem-cells-and-density-gradient-centrifugation-preparation-methods-on-pregnancy-in-intrauterine-insemination-cycles-an-rct
#4
Hoda Fazaeli, Faezeh Davoodi, Naser Kalhor, Reza Tabatabaii Qomi
Background: One of the most important involved factors in pregnancy occurrence following intrauterine insemination (IUI) is semen sample preparation. Recently, supernatant product of adipose tissue derived mesenchymal stem cells (SPAS) method has been shown to improve semen parameters. Objective: To compare the effect of preparation methods in order to IUI, SPAS and density gradient centrifugation (DGC). Materials and Methods: This trial was done on 80 couples with male factor infertility who attend jihad daneshgahi infertility treatment center of Qom province, undergoing ovarian stimulation and IUI cycle...
March 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29765499/effect-of-heat-stress-on-sperm-dna-protamine-assessment-in-ram-spermatozoa-and-testicle
#5
Thais Rose Dos Santos Hamilton, Adriano Felipe Perez Siqueira, Letícia Signori de Castro, Camilla Mota Mendes, Juliana de Carvalho Delgado, Patrícia Monken de Assis, Leonardo Pereira Mesquita, Paulo César Maiorka, Marcílio Nichi, Marcelo Demarchi Goissis, José Antonio Visintin, Mayra Elena Ortiz D Ávila Assumpção
Sperm DNA fragmentation is considered one of the main causes of male infertility. The most accepted causes of sperm DNA damage are deleterious actions of reactive oxygen species (ROS), defects in protamination, and apoptosis. Ram sperm are highly prone to those damages due to the high susceptibility to ROS and to oxidative stress caused by heat stress. We aimed to evaluate the effects of heat stress on the chromatin of ejaculated and epididymal sperm and the activation of apoptotic pathways in different cell types in ram testis...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29765438/decline-in-ovarian-reserve-may-be-an-undiagnosed-reason-for-unexplained-infertility-a-cohort-study
#6
Burak Yücel, Sefa Kelekci, Emine Demirel
Introduction: Unexplained infertility refers to the absence of a definable cause for a couple's failure to achieve pregnancy. Reproductive aging plays a role in pathogenesis of unexplained infertility. We investigated the results of ovarian reserve tests in unexplained infertility. Material and methods: The patients were divided into two groups: unexplained infertility ( n = 148) and male factor infertility ( n = 112). Follicle-stimulating hormone, estradiol, inhibin b levels and anti-Müllerian hormone levels were evaluated...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29753607/maternal-immunization-with-a-dna-vaccine-candidate-elicits-specific-passive-protection-against-post-natal-zika-virus-infection-in-immunocompetent-balb-c-mice
#7
Ran Wang, Xianzheng Liao, Dongying Fan, Lei Wang, Ji Song, Kaihao Feng, Mingyuan Li, Peigang Wang, Hui Chen, Jing An
Zika virus (ZIKV) infection is closely associated in the fetus with microcephaly and in the adults with Guillain-Barré syndrome and even male infertility. It is an urgent international priority to develop a safe and effective vaccine that offers protection to both women of childbearing age and their children. In this study, female immunocompetent BALB/c mice were immunized with a DNA-based vaccine candidate, pVAX1-ZME, expressing the prM/E protein of ZIKV, and the immunogenicity for maternal mice and the post-natal protection for suckling mice were evaluated...
May 9, 2018: Vaccine
https://www.readbyqxmd.com/read/29744474/utilization-of-cryopreserved-sperm-cells-based-on-the-indication-for-storage
#8
Graham Luke Machen, Stephanie E Harris, Erin T Bird, Monica L Brown, Dale A Ingalsbe, Milaida M East, Michelle Reyes, Thomas J Kuehl
Purpose: Cryopreservation of sperm from human semen has been available since the 1950s. The actual utilization of available cryopreservation technology has been infrequently reported. We set out to examine the utilization and outcomes of cryopreserved sperm cells based on the indication for storage. Materials and Methods: A dataset was developed from retrospective review. The purposes for cryopreservation, eventual utilization, and outcomes of use for insemination were recorded...
May 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29737873/adamts1-and-adamts5-metalloproteases-produced-by-sertoli-cells-a-potential-diagnostic-marker-in-azoospermia
#9
Oya Sena Aydos, Yunus Yukselten, Sinan Ozkavukcu, Asuman Sunguroglu, Kaan Aydos
In this study, our aim was to detect protein levels of A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1 and 5 (ADAMTS1 and ADAMTS5) proteases and to examine the effect of in vitro FSH supplementation on protease production in cultured Sertoli cells. The expression of metalloproteases, ADAMTS1, and ADAMTS5 were investigated in Sertoli cell cultures as well as in ejaculate of azoospermic men which then were compared with ejaculates of the fertile control group. A total of 15 azoospermic men, diagnosed as obstructive (OA, n = 5) and nonobstructive (NOA, n = 10) azoospermia were included in the study...
May 8, 2018: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/29732590/preparation-and-observation-methods-can-produce-misleading-artefacts-in-human-sperm-ultrastructural-morphology
#10
W-J Zhu
The aim of this study was to evaluate the production of artefacts during preparation and observation of human sperm for ultrastructural morphology and analyse the possible reasons of causing these artefacts. Under the scanning electron microscopy, damaged sperm heads (crack or/and rupture), necks (head-neck or head-midpiece separation) and midpiece (disassembled and denuded axoneme ultrastructures, bent midpiece) were analysed to be the consequence of exogenous effects. Thirty infertile men with teratozoospermia revealed more spermatozoa with damage to head, neck and midpiece than did thirty fertile males (p < ...
May 7, 2018: Andrologia
https://www.readbyqxmd.com/read/29731401/adverse-effects-of-common-sports-and-recreational-activities-on-male-reproduction
#11
REVIEW
Kush Panara, John M Masterson, Luis F Savio, Ranjith Ramasamy
CONTEXT: Male factor infertility plays a significant role in infertility. Many factors have been associated with male infertility; however, the link between many sports and recreational factors and male reproduction remains poorly characterized. OBJECTIVE: To evaluate the current literature regarding the impact of many common sports and recreational factors on male reproduction. EVIDENCE ACQUISITION: A comprehensive PubMed and Embase search for relevant articles published between 1970 and 2017 was performed by combining the following search terms: male, sports (including individual sports), traumatic brain injury, sauna, hot tub, fertility, erectile dysfunction, varicocele, environment, cell phone, and laptop computer...
May 3, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29730678/reliability-of-testicular-stiffness-quantification-using-shear-wave-elastography-in-predicting-male-fertility-a-preliminary-prospective-study
#12
Alpaslan Yavuz, Adem Yokus, Kerem Taken, Abdussamet Batur, Mesut Ozgokce, Harun Arslan
AIMS: To evaluate the reliability of testicular stiffness quantification using shear wave elastography in predicting the fertility potential of males and for the pre-diagnosis of disorders based upon sperm quantification. MATERIAL AND METHODS: One hundred males between the ages of 19-49 years (mean age of 28.77±6.11), ninety of whom with complaints of infertility, were enrolled in this prospective study. Scrotal grey-scale, Doppler ultrasound (US), and mean testicular shear wave velocity quantifications (SWVQs) were performed...
May 2, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/29729871/sports-related-male-infertility
#13
Kathleen Hwang, David Guo
Many common sports and sports-related behaviors and practices represent potential sources of male infertility. Clinicians should be aware of these associations in the evaluation of idiopathic infertility in men.
May 2, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29729841/cadmium-effects-on-sperm-morphology-and-semenogelin-with-relates-to-increased-ros-in-infertile-smokers-an-in-vitro-and-in-silico-approach
#14
Parameswari Ranganathan, Kamini A Rao, Jesu Jaya Sudan, Sridharan Balasundaram
Smoking releases cadmium (Cd), the metal toxicant which causes an imbalance in reactive oxygen species level in seminal plasma. This imbalance is envisaged to impair the sperm DNA morphology and thereby result in male infertility. In order to correlate this association, we performed in vitro and in silico studies and evaluated the influence of reactive oxygen species imbalance on sperm morphology impairments due to smoking. The study included 76 infertile smokers, 72 infertile non-smokers, 68 fertile smokers and 74 fertile non-smokers (control)...
May 2, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/29729157/the-research-of-medical-and-social-factors-of-the-risk-of-reproductive-health-of-men-by-family-doctor
#15
Serhii Yu Tsiporenko, Larysa F Matyucha
OBJECTIVE: Introduction: One of the important modern problems in the practice of a family doctor is the protection of reproductive health. Reproductive problems in marriage, including male infertility, are important components of demographic processes, therefore, attempts to resolve them are not only medical, but also social significance. Of all the physiological systems of man, for which the patterns of adaptation mechanisms are shown, the most "vulnerable" is the reproductive system, whose functioning depends on the set of exo- and endogenous influences...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29726647/-rna-simultaneous-and-amplification-testing-versus-the-culture-method-for-detecting-ureaplasma-urealyticum-infection
#16
Qu Zheng, Wei Liu, Guo-Wei Zhang, Kai-Qiang Li, Ling-Ling Wang, Jing-Ping Ge, Zhi-Qiang Weng, Xue-Jun Shang
Objective: To investigate the value of real-time RNA simultaneous amplification and testing (SAT) in the detection of Ureaplasma urealyticum (UU) in the semen of infertile males and its clinical significance. METHODS: We collected semen samples from 542 infertility patients and 120 normal fertile men as controls in the Andrology Clinic of Nanjing General Hospital from March to September 2015. We detected UU infection in the samples using the culture method and SAT technology, respectively...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29717166/comparative-proteomics-reveal-the-association-between-spanx-proteins-and-clinical-outcomes-of-artificial-insemination-with-donor-sperm
#17
X M Wang, Z Xiang, Y Fu, H L Wu, W B Zhu, L Q Fan
Semen analysis is used for diagnosing male infertility and evaluating male fertility for more than a century. However, the semen analysis simply represents the population characteristics of sperm. It is not a comprehensive assessment of the male reproductive potential. In this study, 20 semen samples from human sperm bank with distinctive artificial insemination with donor sperm (AID) clinical outcomes were collected and analyzed using a two-dimensional differential in-gel electrophoresis (2D-DIGE); 45 differentially expressed protein spots were obtained, and 26 proteins were identified...
May 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29713540/prediction-of-male-infertility-by-the-world-health-organization-laboratory-manual-for-assessment-of-semen-analysis-a-systematic-review
#18
REVIEW
Amir S Patel, Joon Yau Leong, Ranjith Ramasamy
Objective: To discuss the role, reliability and limitations of the semen analysis in the evaluation of fertility with reference to the World Health Organization (WHO) fifth edition guidelines, with semen analysis reference values published in 2010. We also discuss the limitations of using a single threshold value to distinguish 'abnormal' and 'normal' parameters. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to search the MEDLINE, EMBASE, and the Cochrane electronic database for articles discussing the effectiveness of semen analysis...
March 2018: Arab Journal of Urology
https://www.readbyqxmd.com/read/29713538/laboratory-assessment-of-oxidative-stress-in-semen
#19
Ashok Agarwal, Emily Qiu, Rakesh Sharma
Objectives: To evaluate different laboratory assessments of oxidative stress (OS) in semen and identify a cost-efficient and highly sensitive instrument capable of providing a comprehensive measure of OS in a clinical setting, as early intervention and an accurate diagnostic test are important because they help maintain a balance of free radicals and antioxidants; otherwise, excessive OS could lead to sperm damage and result in male infertility. Materials and methods: A systematic literature search was performed through a MedLine database search using the keywords 'semen' AND 'oxygen reduction potential'...
March 2018: Arab Journal of Urology
https://www.readbyqxmd.com/read/29713535/hyperprolactinaemia-in-male-infertility-clinical-case-scenarios
#20
Zeinab Dabbous, Stephen L Atkin
Objective: To explore the evaluation, treatment and impact of hyperprolactinaemia on male infertility and testicular function, as hyperprolactinaemia is commonly detected during the evaluation of infertile men. Methods: A literature search was performed using MEDLINE/PubMed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to identify all studies exploring hyperprolactinaemia in male infertility. Results: Elevated levels of serum prolactin have a detrimental effect on male reproduction through inhibition of the pulsatile release of gonadotrophins from the anterior pituitary gland, and a direct effect on spermatogenesis...
March 2018: Arab Journal of Urology
keyword
keyword
115890
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"