keyword
https://read.qxmd.com/read/38394948/abnormal-supplementary-motor-areas-are-associated-with-idiopathic-and-acquired-blepharospasm
#1
JOURNAL ARTICLE
Jinping Xu, Xiaodong Zhang, Qinxiu Cheng, Haoran Zhang, Linchang Zhong, Yuhan Luo, Yue Zhang, Zilin Ou, Zhicong Yan, Kangqiang Peng, Gang Liu
Blepharospasm is a common form of focal dystonia characterized by excessive and involuntary spasms of the orbicularis oculi. In addition to idiopathic blepharospasm, lesions in various brain regions can also cause acquired blepharospasm. Whether these two types of blepharospasm share a common brain network remains largely unknown. Herein, we performed lesion coactivation network mapping, based on meta-analytic connectivity modeling, to test whether lesions causing blepharospasm could be mapped to a common coactivation brain network...
February 9, 2024: Parkinsonism & related Disorders
https://read.qxmd.com/read/38222680/double-aneuploidy-in-a-2-month-old-male-with-edward-syndrome-and-klinefelter-syndrome-a-case-report
#2
Marah Mansour, Ahmed AlZoubi, Sham Zoukar, Ghina Aljammal, Raghad Makki, Noor Al Huda Khaled, Yara Aletesh, Rama Aljundi, Ahmad Mohammad Deeb, Mohammad Obada Ajlouni
INTRODUCTION AND IMPORTANCE: Edward syndrome is a severe chromosomal defect that occurs as a result of non-disjunction through meiosis. It presents with cardiac septal defects, horseshoe kidneys, patent ductus arteriosus, central nervous system dysgenesis, distinctive craniofacial deformities, and overriding or overlapping fingers. Klinefelter syndrome (47, XXY) is found in 1 in 660 newborn males. It is considered to be one of the most common genetic causes of infertility. It manifests with small firm testes, androgen insufficiency, and azoospermia...
January 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/37891802/a-new-finding-on-magnetic-resonance-imaging-for-diagnosis-of-hemifacial-spasm-with-high-accuracy-and-interobserver-correlation
#3
JOURNAL ARTICLE
Guilherme Finger, Kyle C Wu, Joshua Vignolles-Jeong, Saniya S Godil, Ben G McGahan, Daniel Kreatsoulas, Mohammad T Shujaat, Luciano M Prevedello, Daniel M Prevedello
Among patients with clinical hemifacial spasm (HFS), imaging exams aim to identify the neurovascular conflict (NVC) location. It has been proven that the identification in the preoperative exam increases the rate of surgical success. Despite the description of specific magnetic resonance image (MRI) acquisitions, the site of neurovascular compression is not always visualized. The authors describe a new MRI finding that helps in the diagnosis of HFS, and evaluate the sensitivity, specificity, and interobserver correlation of the described sign...
October 9, 2023: Brain Sciences
https://read.qxmd.com/read/37819413/hypocalcemia-in-combination-with-hyperphosphatemia-impairs-muscle-cell-differentiation-in-vitro
#4
JOURNAL ARTICLE
V M Bimonte, G Catanzaro, Z Spinello, M C Massari, M Curreli, G Terrana, G Defeudis, J Halupczok-Żyła, G Mantovani, E Ferretti, S Migliaccio
PURPOSE: Hypoparathyroidism is a rare endocrine disorder characterized by low or absent secretion of parathyroid hormone (PTH), which leads to decreased calcium and increased phosphorus levels in the serum. The diagnosis of hypoparathyroidism is based on the identification of the aforementioned biochemical abnormalities, which may be accompanied by clinical manifestations. Symptoms of hypoparathyroidism, primarily attributed to hypocalcemia, include muscle cramps or spasms, facial, leg, and foot pain, seizures, and tingling in the lips or fingers...
October 11, 2023: Journal of Endocrinological Investigation
https://read.qxmd.com/read/37551417/epidemiology-of-injuries-during-iran-wheelchair-basketball-professional-league-predictive-risk-factors-and-prevention-strategies
#5
JOURNAL ARTICLE
Mohammadreza Mahmoudkhani, Mehdi Norouzi, Zahra Fathi, Behnaz Charehjoo, Mona Oftadehgan, Fatemeh Alizadeh, Mahsa Miri
BACKGROUND: Very few studies have investigated athletes with disabilities during a long period of competitions, such as a professional league. Also, there are limited findings related to specific mechanisms and risk factors of injury, and prevention strategies in Wheelchair Basketball. Therefore, the objective of this study was to investigate the rate and characteristics of injuries in the 2021-2022 Iran Wheelchair Basketball League and present prevention strategies. METHODS: This retrospective study was conducted after the 2021-2022 (Mar 2021-Sep 2022) competition season...
August 7, 2023: Journal of Injury & Violence Research
https://read.qxmd.com/read/37501199/hypocalcemic-tetany-associated-with-simultaneous-administration-of-cimetidine-and-nifedipine-a-case-report
#6
JOURNAL ARTICLE
Yihienew M Bezabih, Mekides A Bimrew, Woldesellassie M Bezabhe
BACKGROUND: Acute hypocalcemia is generally caused by a sudden drop in serum calcium ion and presents with a mild or severe form of tetany. Even though the occurrence of hypocalcemia is well documented with certain drugs such as calcium chelators, bisphosphonates, and cisplatin, it is a very unusual and poorly documented adverse event with cimetidine and nifedipine. Here, we present a case of severe hypocalcemic tetany during simultaneous administration of cimetidine and nifedipine in a hypertensive patient with dyspepsia...
July 28, 2023: Journal of Medical Case Reports
https://read.qxmd.com/read/37335237/finger-exercise-could-reduce-painfulness-and-radial-artery-complications-related-to-coronary-artery-angiography
#7
JOURNAL ARTICLE
Kai Zhang, Peng Hu, Lin Zhao, Liqin Cai, Yi Zhang
OBJECTIVE: To estimate if applying a finger exercise during trans-radial coronary artery angiography (CAG) could help to reduce a patient's painfulness and evaluate its protective effects against radial artery complications. METHODS: This is a prospective, controlled, single-center trial. Overall, 390 patients who underwent coronary angiography through radial path in our hospital during 2022 were randomized 1 : 1 to the following two groups: test group: finger exercise in addition to routine perioperative care; control group: routine care...
June 13, 2023: Coronary Artery Disease
https://read.qxmd.com/read/37301824/a-randomized-controlled-trial-evaluating-the-short-term-efficacy-of-a-single-administration-intramuscular-injection-with-the-fixed-combination-of-thiocolchicoside-diclofenac-versus-diclofenac-monotherapy-in-patients-with-acute-moderate-to-severe-low-back-pain
#8
JOURNAL ARTICLE
Konstantinos Iliopoulos, Panagiota Koufaki, Stavros Tsilikas, Kyriakos Avramidis, Antonios Tsagkalis, Clio Mavragani, Elias Zintzaras
BACKGROUND: Non-specific acute low back pain (LBP) is a common health problem that may be accompanied by muscle spasm and decreased mobility. The combination of non-steroidal anti-inflammatory drugs and muscle relaxants represents an advantageous therapeutic option, however, available data on their combined use are conflicting. This prospective, randomized, single-blind, two-parallel-group trial assessed the efficacy of a single intramuscular (IM) injection of the fixed-dose combination (FDC) diclofenac (75 mg)-thiocolchicoside (4 mg/4 ml) product (test treatment) compared to diclofenac (75 mg/3 ml) alone (reference treatment) for the symptomatic relief of acute LBP...
June 10, 2023: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/37055560/topological-differences-and-confounders-of-mental-rotation-in-cervical-dystonia-and-blepharospasm
#9
JOURNAL ARTICLE
Thorsten M Odorfer, Marie Yabe, Shawn Hiew, Jens Volkmann, Daniel Zeller
Mental rotation (mR) bases on imagination of actual movements. It remains unclear whether there is a specific pattern of mR impairment in focal dystonia. We aimed to investigate mR in patients with cervical dystonia (CD) and blepharospasm (BS) and to assess potential confounders. 23 CD patients and 23 healthy controls (HC) as well as 21 BS and 19 hemifacial spasm (HS) patients were matched for sex, age, and education level. Handedness, finger dexterity, general reaction time, and cognitive status were assessed...
April 13, 2023: Scientific Reports
https://read.qxmd.com/read/37035517/laminar-vaso-fmri-in-focal-hand-dystonia-patients
#10
JOURNAL ARTICLE
Laurentius Huber, Panagiotis Kassavetis, Omer Faruk Gulban, Mark Hallett, Silvina G Horovitz
Focal Hand Dystonia (FHD) is a disabling movement disorder characterized by involuntary movements, cramps and spasms. It is associated with pathological neural microcircuits in the cortical somatosensory system. While invasive preclinical modalities allow researchers to probe specific neural microcircuits of cortical layers and columns, conventional functional magnetic resonance imaging (fMRI) cannot resolve such small neural computational units. In this study, we take advantage of recent developments in ultra-high-field MRI hardware and MR-sequences to capture altered digit representations and laminar processing in FHD patients...
2023: Dystonia
https://read.qxmd.com/read/36319147/-genetics-and-clinical-phenotypes-of-epilepsy-associated-with-chromosome-2q24-3-microdeletion
#11
JOURNAL ARTICLE
N Zhao, M M Cheng, Y Yang, X Y Niu, Y Chen, X L Yang, Y H Zhang
Objective: To summarize the genetics and clinical phenotypes of epilepsy children with 2q24.3 microdeletion. Methods: All the patients with 2q24.3 microdeletion were retrospectively collected at the Pediatric Department of Peking University First Hospital from March 2017 to July 2022. The features of clinical manifestations, electroencephalogram (EEG), and neuroimaging were analyzed. Results: There were 13 patients with 2q24.3 microdeletion were included. All 13 patients had de novo copy number variation (CNV) with a deletion size ranged 0...
November 2, 2022: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/36281446/a-rarely-occurring-spinal-fracture-precipitated-by-generalized-spasms-of-tetanus-patient-with-spondylitis-tuberculosis
#12
Fathul Huda, Paulus Anam Ong, Yusuf Wibisono, Sofiati Dian, Ahmad Rizal Ganiem
Background: The occurrence of spinal fracture due to tetanus nowadays is extremely rare, as compared to the 1950s, since the widely available anti-tetanus and antispasmodic therapy. The spinal fracture in tetanus patients is usually reported in higher thoracic vertebrae, previously with a rate as high as 57.5%. Spondylitis is the most common form of skeletal tuberculosis (TB) and can cause a spinal fracture. In Indonesia, tetanus is still reported, while tuberculosis is still endemic; however, co-infection of both diseases is rarely reported...
2022: International Medical Case Reports Journal
https://read.qxmd.com/read/35764314/use-of-doppler-ultrasound-for-early-rehabilitation-of-replanted-hand-and-finger
#13
JOURNAL ARTICLE
Takashi Kageyama, Hokuto Morii, Koichi Inokuchi
No abstract text is available yet for this article.
September 26, 2022: Journal of Reconstructive Microsurgery
https://read.qxmd.com/read/35712943/-treatment-of-finger-spasm-after-stroke-with-wheat-grain-moxibustion-at-shixuan-ex-ue-11-combined-with-rehabilitation-training-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Li Niu, Yan-Jie Li, He-Wei Qin, Ning Guo, Hao-Yuan Liu, Xiao-Qiong Hua, Shu-Qin Zhang, Yu-Bin Sun
OBJECTIVE: To compare the clinical effect of wheat grain moxibustion combined with rehabilitation training and simple rehabilitation training on finger spasm after stroke. METHODS: A total of 80 patients with finger spasm after stroke were randomly divided into an observation group and a control group, 40 cases in each group. The control group was given routine rehabilitation training, once a day, 30 min each time. The observation group was given wheat grain moxibustion at Shixuan (EX-UE 11) on the basis of the control group, 8~10 moxibustion cones at each point, once a day...
June 12, 2022: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://read.qxmd.com/read/34430883/complex-region-pain-syndrome-following-shoulder-surgery
#15
JOURNAL ARTICLE
Kevin M Magone, Erel Ben-Ari, Jacques H Hacquebord, Mandeep S Virk
PURPOSE: To describe the clinical features, treatment, and outcomes in patients with complex region pain syndrome (CRPS) following shoulder surgeries. METHODS: Three patients were diagnosed with CRPS according to the Budapest criteria. Patients were followed up prospectively at regular intervals for a minimum of 2 years. Demographic data, clinical symptoms, physical examination findings, treatment received, and outcomes were collected and reported. RESULTS: The minimum time interval between surgery and diagnosis was 3 weeks (average, 8 weeks)...
August 2021: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/33814721/long-term-effects-of-combined-botulinum-toxin-treatment-and-rehabilitation-on-upper-limb-muscle-spasms-a-case-report
#16
Kazuo Saito, Yumiko Saito, Kyoko Hirota, Hirotaka Matui, Kimitaka Hase
[Purpose] We report our experience with a patient with a central spinal cord injury who showed improved finger and upper limb functions after long-term treatment with a combination of rehabilitation and botulinum toxin type A. [Participants and Methods] The patient had spasms and pain that gradually became more profound and was given botulinum toxin type A at 1 year 3 months after sustaining a spinal cord injury. We administered 14 botulinum toxin type A injections periodically for 7 years 4 months after the injury...
March 2021: Journal of Physical Therapy Science
https://read.qxmd.com/read/33235514/effects-of-eperisone-hydrochloride-and-non-steroid-anti-inflammatory-drugs-nsaids-for-acute-non-specific-back-pain-with-muscle-spasm-a-prospective-open-label-study
#17
JOURNAL ARTICLE
Rizaldy Taslim Pinzon, Vincent Ongko Wijaya, Dessy Paramitha, Raymondus Rangga Bagaskara
Background: Low back pain (LBP) occurs as a common condition and may harm the patient's quality-of-life. Non-steroid anti-inflammatory drugs (NSAIDs) and eperisone form a drug regiment that has been reported as effective in improving low back pain, yet the evidence for its efficacy and safety is lacking. Objective: The aim of this study was to evaluate the effect of eperisone hydrochloride and ibuprofen compared with ibuprofen alone in reducing symptoms of patients with acute non-specific back pain with a muscle spasm...
2020: Drug, Healthcare and Patient Safety
https://read.qxmd.com/read/32732447/local-infiltration-anaesthesia-with-a-bloodless-operative-field-walant-presentation-of-the-technique-and-its-use-in-hand-surgery
#18
JOURNAL ARTICLE
Andrzej Żyluk, Zbigniew Szlosser
Local infiltration anaesthesia with a bloodless operation field (WALANT) allows for performing hand surgery without a tourniquet. This effect is obtained through an injection of greater than standard volume of the anaesthetic solution composed of lignocaine and adrenaline. The addition of adrenaline induces spasm of small arteries within the infiltration area, which inhibits bleeding and allows visualization of most of the subtle but important structures in the hand and fingers. This article presents a method of preparation of the anaesthetic solution and the technique of anaesthesia for several common procedures in hand surgery...
June 30, 2020: Ortopedia, Traumatologia, Rehabilitacja
https://read.qxmd.com/read/32480268/dynamic-cta-and-mra-in-a-case-of-severe-raynaud-s-phenomenon
#19
Jacqueline L Hislop-Jambrich, John M Troupis, Geoffrey Littlejohn, Ahilan Kuganesan
Raynaud's phenomenon (RP) is a condition where arterial spasm, usually in the fingers, causes episodes of reduced blood flow. The condition is either idiopathic (primary) or related to a connective tissue disorder or drug response (secondary). We present a case of severe RP where we performed a novel-sequenced CTA and MRA during a prolonged active episode of peripheral vasospasm. Real-time multidisciplinary consultation resulted in appropriate therapy with symptoms alleviation within hours of presentation.
October 2020: Clinical Imaging
https://read.qxmd.com/read/32377491/idiopathic-carpal-spasm-trousseau-s-sign-after-intraoperative-arm-tourniquet-inflation-in-an-intubated-patient
#20
Suzanne M Beecher, Stephanie M Bollard, Eamon S Beausang
We present a case of a 38-year-old male who sustained a laceration from a knife to the volar aspect of his left index and middle fingers. He had clinical injury to his flexor digitorum profundus tendons to both digits. He underwent operative exploration and repair of the tendons under general anaesthetic. An arm tourniquet was inflated to allow for haemostasis in the operative field. A few minutes after inflation, the patient's hand went into carpal spasm. The tourniquet was deflated and the spasm resolved...
April 4, 2020: Curēus
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