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Maria Teresa Arias-Moliz, Cher Farrugia, Christie Y K Lung, Pierre Schembri Wismayer, Josette Camilleri
OBJECTIVES: Characterization of a number of pulp capping materials and assessment of the leachate for elemental composition, antimicrobial activity and cell proliferation and expression. METHODOLOGY: Three experimental light curable pulp-capping materials, Theracal and Biodentine were characterized by scanning electron microscopy, energy dispersive spectroscopy and X-ray diffraction. The elemental composition of the leachate formed after 24hours was assessed by inductively coupled plasma (ICP)...
June 20, 2017: Journal of Dentistry
Thomas Giraud, Pierre Rufas, Fanny Chmilewsky, Charlotte Rombouts, Jacques Dejou, Charlotte Jeanneau, Imad About
INTRODUCTION: The role of complement, especially through the C5a fragment, is well-known for the initiation of inflammation. Its involvement in regeneration has been shown more recently by the recruitment of mesenchymal stem cells. C5a can be produced locally by the pulp fibroblasts in response to injury or infection. This work aims to investigate the effect of different pulp capping biomaterials on complement activation and its possible influence on inflammatory and pulp stem cell recruitment...
May 17, 2017: Journal of Endodontics
Bo W Nilsen, Einar Jensen, Ulf Örtengren, Vibeke B Michelsen
The purpose of this study was to elucidate the organic composition and eluates of three resin-based pulp-capping materials in relation to their indications and safety data sheets. Uncured samples of Theracal LC, Ultra-Blend Plus, and Calcimol LC were investigated using gas chromatography-mass spectrometry (GC-MS) and ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Identification/quantification of 7-d leachables of cured samples was performed using GC-MS for 2-hydroxyethyl methacrylate (HEMA), 2-(dimethylamino)ethyl methacrylate (DMAEMA), camphorquinone (CQ), ethylene glycol dimethacrylate (EGDMA), ethyl-4-(dimethylamino)benzoate (DMABEE), and triethylene glycol dimethacrylate (TEGDMA)...
June 2017: European Journal of Oral Sciences
Markus Fuss, Michael J Wicht, Thomas Attin, Sonja H M Derman, Michael J Noack
PURPOSE: To investigate the buffering capacity of restorative materials during a simulated carious and intrinsic erosive attack. MATERIALS AND METHODS: Cavities with a volume of 130 μl were milled (Cerec MC XL) out of blocks of Ceram X Mono (CM), Quixfil (QX), Filtek Supreme (FS), Apa Fill 3 (AF), an experimental dual-curing composite containing a bioactive glass (EX), Dyract eXtra (DY), Beautifil (BE), Equia Fil (EQ), Telio CAD (TL) (negative control), TheraCal (TC; positive control), and extracted teeth (ED)...
April 25, 2017: Journal of Adhesive Dentistry
M Collado-González, D García-Bernal, R E Oñate-Sánchez, P S Ortolani-Seltenerich, T Álvarez-Muro, A Lozano, L Forner, C Llena, J M Moraleda, F J Rodríguez-Lozano
AIMS: To investigate the cytotoxicity and bioactivity of several pulpotomy materials: Biodentine (Septodont, Saint-Maur-des-Fosses, France) MTA (Angelus, Londrina, PR, Brazil), Theracal LC (Bisco Inc., Schamburg, IL, USA) and IRM (Dentsply DeTrey GmbH, Konstanz, Germany), after contact with stem cells isolated from human exfoliated primary teeth (SHEDs). METHODOLOGY: SHEDs were cultured in the presence of the eluates of various pulpotomy materials for 24, 48 and 72 h...
February 7, 2017: International Endodontic Journal
Victor Gong, Rodrigo França
OBJECTIVES: The surface of any dental pulp-capping material has important implications for its clinical success because it is in direct contact with dental tissue, which influences its cytotoxicity. The aim was to determine the chemical composition of the first atomic layers of four pulp-protection agents because these atoms can initiate the pulp healing process. METHODS: Biodentine (Septodont), ProRoot MTA (Dentsply), Dycal (Caulk) and TheraCal (Bisco) were prepared (n=5) according to manufacturer recommendations...
December 30, 2016: Journal of Dentistry
Navya P Menon, Balagopal R Varma, Sureshkumar Janardhanan, Parvathy Kumaran, Arun Mamachan Xavier, Bhat Sangeetha Govinda
AIM: To clinically and radiographically evaluate the reparative dentin formation in indirect pulp treatment (IPT) using mineral trioxide aggregate (MTA) and light cured calcium silicate (TheraCal) in primary molars over a period of 6 months. MATERIALS AND METHODS: A clinical trial on IPT on 43 primary molars in 21 patients between the age of 4-7 years, divided into two groups: 22 teeth in MTA group and 21 in TheraCal group. Measurement of the variation in dentin thickness was done on the digitalized radiograph at baseline, 3 months and 6 months using CorelDRAW X3 software...
October 2016: Contemporary Clinical Dentistry
S Yamamoto, L Han, Y Noiri, T Okiji
AIM: To evaluate the Ca(2+) -releasing, alkalizing, and apatite-like surface precipitate-forming abilities of a prototype tricalcium silicate cement, which was mainly composed of synthetically prepared tricalcium silicate and zirconium oxide radiopacifier. METHODOLOGY: The prototype tricalcium silicate cement, white ProRoot MTA (WMTA), and TheraCal LC (a light-cured resin-modified calcium silicate-filled material) were examined. The chemical compositions were analyzed with a wavelength-dispersive X-ray spectroscopy electron probe microanalyzer with an image observation function (SEM-EPMA)...
December 15, 2016: International Endodontic Journal
K Demirkaya, B Can Demirdöğen, Z Öncel Torun, O Erdem, E Çırak, Y M Tunca
Mineral trioxide aggregate (MTA) is a calcium silicate dental cement used for various applications in dentistry. This study was undertaken to test whether the presence of three commercial brands of calcium silicate dental cements in the dental extraction socket of rats would affect the brain aluminium (Al) levels and oxidative stress parameters. Right upper incisor was extracted and polyethylene tubes filled with MTA Angelus, MTA Fillapex or Theracal LC, or left empty for the control group, were inserted into the extraction socket...
November 27, 2016: Human & Experimental Toxicology
Hanan Alzraikat, Nessrin A Taha, Deema Qasrawi, Michael F Burrow
The shear bond strength (SBS) of TheraCal LC to resin composite was evaluated in comparison to Mineral trioxide aggregate (ProRoot MTA) and conventional glass ionomer cement (GIC) using two adhesive systems. A hole was prepared in 90 acrylic blocks (6 mm diameter, 2 mm deep) then filled with TheraCal LC, MTA or Fuji IX (n=30/group). Each group was bonded with either an etch and rinse or 1-step self-etch adhesive. Filtek Z250 composite was bonded to each capping material. Bond strength was tested in a universal testing machine, and data were analyzed using 2-way ANOVA and Duncan's Multiple range test (p<0...
December 1, 2016: Dental Materials Journal
Velagala L Deepa, Bhargavi Dhamaraju, Indira Priyadharsini Bollu, Tandri S Balaji
AIMS: To compare and evaluate the bonding ability of resin composite (RC) to three different liners: TheraCal LC™ (TLC), a novel resin-modified (RM) calcium silicate cement, Biodentine™ (BD), and resin-modified glass ionomer cement (RMGIC) using an universal silane-containing adhesive and characterizing their failure modes. MATERIALS AND METHODS: Thirty extracted intact human molars with occlusal cavity (6-mm diameter and 2-mm height) were mounted in acrylic blocks and divided into three groups of 10 samples each based on the liner used as Group A (TLC), Group B (BD), and Group C (RMGIC)...
March 2016: Journal of Conservative Dentistry: JCD
Esra Cengiz, Nuran Ulusoy
PURPOSE: To evaluate the microshear bond strength of tri-calcium silicate-based materials to different restorative materials. MATERIALS AND METHODS: Thirty-five disks of TheraCal LC and Biodentine were fabricated using teflon molds according to manufacturers' instructions. Then the specimens were randomly divided into 7 groups according to the materials applied: Fuji IX, Fuji II, Equia Fil, Vertise Flow, Filtek Bulk Fill Posterior Restorative, Filtek Z250 with Prime&Bond NT and with Clearfil SE Bond...
2016: Journal of Adhesive Dentistry
B-N Lee, B-G Lee, H-S Chang, Y-C Hwang, I-N Hwang, W-M Oh
AIM: To assess the biological effects, including odontoblastic differentiation of a novel light-curable material (TheraCal), on human dental pulp cells (hDPCs). METHODOLOGY: The hDPCs were isolated from freshly extracted, caries-free third molars. Ten discs of TheraCal and MTA (8 mm in diameter and 3 mm in height) were incubated in α-minimum essential medium (α-MEM) and the supernatant collected. Viability of hDPCs in response to TheraCal and MTA was measured using the WST-1 assay...
May 2017: International Endodontic Journal
Matthew J Nielsen, Jeffery A Casey, Richard A VanderWeele, Kraig S Vandewalle
The mechanical properties of pulp-capping materials may affect their resistance to fracture during placement of a final restorative material or while supporting an overlying restoration over time. The purpose of this study was to compare the compressive strength, flexural strength, and flexural modulus of 2 new pulp-capping materials (TheraCal LC and Biodentine), mineral trioxide aggregate (MTA), and calcium hydroxide over time. Specimens were created in molds and tested to failure in a universal testing machine after 15 minutes, 3 hours, and 24 hours...
January 2016: General Dentistry
Esra Cengiz, Hasan Guney Yilmaz
INTRODUCTION: The purpose of this randomized clinical study was to evaluate the efficiency of erbium, chromium-doped:yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser irradiation combined with a resin-based tricalcium silicate material and calcium hydroxide in direct pulp capping for a 6-month follow-up period. METHODS: A total of 60 teeth of 60 patients between the ages of 18 and 41 years were recruited for this study. Sixty permanent vital teeth without symptoms and radiographic changes were randomly assigned to the following 4 groups (n = 15): Gr CH, the exposed area was sealed with calcium hydroxide (CH) paste; Gr laser CH, the treated area was sealed with CH paste after Er,Cr:YSGG laser irradiation at an energy level of 0...
March 2016: Journal of Endodontics
Kadriye Demirkaya, Birsen Can Demirdöğen, Zeynep Öncel Torun, Onur Erdem, Serdar Çetinkaya, Cemal Akay
Our aim was to test whether the presence of three hydraulic calcium silicate dental cements--MTA Angelus, MTA Fillapex, and Theracal LC--in the dental extraction socket of an in vivo model, would affect the levels of aluminium (Al) in the plasma and liver. Following anesthesia, the right upper incisor of each male Wistar albino rat was extracted and polyethylene tubes filled with MTA Angelus, MTA Fillapex, or Theracal LC were inserted into the depth of the extraction socket and gingival tissue was sutured. The rats were killed 7, 30, or 60 d after the operation...
February 2016: European Journal of Oral Sciences
Claudio Poggio, Riccardo Beltrami, Marco Colombo, Matteo Ceci, Alberto Dagna, Marco Chiesa
BACKGROUND: Direct pulp capping involves the application of a dental material to seal communications between the exposed pulp and the oral cavity (mechanical and carious pulp exposures) in an attempt to act as a barrier, protect the dental pulp complex and preserve its vitality. The aim of this study was to evaluate and compare, by the agar disc diffusion test, the antimicrobial activity of six different pulp-capping materials: Dycal (Dentsply), Calcicur (Voco), Calcimol LC (Voco), TheraCal LC (Bisco), MTA Angelus (Angelus), Biodentine (Septodont)...
December 2015: Journal of Clinical and Experimental Dentistry
Muhammed Karadas, Kenan Cantekin, Husniye Gumus, Sabit Melih Ateş, Zeynep Yesil Duymuş
This study evaluated the bond strength of different adhesive agents to TheraCal LC and mineral trioxide aggregate (MTA) and examined the morphologic changes of these materials with different surface treatments. A total of 120 specimens, 60 of MTA Angelus (AMTA), and 60 of TheraCal LC, were prepared and divided into six subgroups according to the adhesive agent used; these agents included Scotchbond Multipurpose, Clearfil SE Bond, Clearfil Protect Bond, Clearfil S(3) Bond, OptiBond All-in-One, and G-aenial Bond...
September 2016: Scanning
Eduardo A Bortoluzzi, Li-Na Niu, Chithra D Palani, Ahmed R El-Awady, Barry D Hammond, Dan-Dan Pei, Fu-Cong Tian, Christopher W Cutler, David H Pashley, Franklin R Tay
OBJECTIVES: In pulpal revascularization, a protective material is placed coronal to the blood clot to prevent recontamination and to facilitate osteogenic differentiation of mesenchymal stem cells to produce new dental tissues. Although mineral trioxide aggregate (MTA) has been the material of choice for clot protection, it is easily displaced into the clot during condensation. The present study evaluated the effects of recently introduced calcium silicate cements (Biodentine and TheraCal LC) on the viability and osteogenic differentiation of human dental pulp stem cells (hDPSCs) by comparing with MTA Angelus...
December 2015: Dental Materials: Official Publication of the Academy of Dental Materials
Claudio Poggio, Matteo Ceci, Alberto Dagna, Riccardo Beltrami, Marco Colombo, Marco Chiesa
Direct pulp capping covers the exposed surface of the pulp to maintain its vitality and preserve its functional and biologic activity. The aim of the present study was to compare the biocompatibility effects of seven different pulp-capping materials in vitro: Dycal®, Calcicur®, Calcimol LC®, TheraCal LC®, ProRoot MTA®, MTA-Angelus®, and Biodentine®. Using the Transwell insert methodology by Alamar blue test, we evaluated the cytocompatibility of the above mentioned materials towards murine odontoblasts cells (MDPC-23) at three different times (24, 48, and 72 h)...
September 1, 2015: Arhiv za Higijenu Rada i Toksikologiju
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