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https://www.readbyqxmd.com/read/28544989/impact-of-mediolateral-episiotomy-on-incidence-of-obstetrical-anal-sphincter-injury-diagnosed-by-endoanal-ultrasound
#1
Kristina Drusany Staric, Adolf Lukanovic, Petra Petrocnik, Vita Zacesta, Corrado Cescon, Miha Lucovnik
OBJECTIVE: to examine potential association between mediolateral episiotomy and reduced incidence of obstetrical anal sphincter injuries (OASIS) diagnosed by endoanal ultrasound. DESIGN: prospective cohort study. SETTING: tertiary referral university hospital. PARTICIPANTS: sixty nulliparous women at 28-33 weeks of gestation with singleton pregnancies were included between 2010 and 2012. MEASUREMENTS AND FINDINGS: participants were examined with endoanal ultrasound at 28-33 weeks gestation and at 6-7 weeks post-partum...
May 18, 2017: Midwifery
https://www.readbyqxmd.com/read/28537100/cerebrospinal-fluid-neurofilament-light-levels-mark-grey-matter-volume-in-clinically-isolated-syndrome-suggestive-of-multiple-sclerosis
#2
Carla Tortorella, Vita Direnzo, Maddalena Ruggieri, Stefano Zoccolella, Mariangela Mastrapasqua, Mariangela D'Onghia, Damiano Paolicelli, Franca Di Cuonzo, Claudio Gasperini, Maria Trojano
BACKGROUND: Brain atrophy is a known marker of irreversible tissue damage in multiple sclerosis (MS). Cerebrospinal fluid (CSF) osteopontin (OPN) and neurofilament light chain (NF-L) have been proposed as candidate surrogate markers of inflammatory and neurodegenerative processes in MS. OBJECTIVE: To evaluate the relationship between CSF NF-L and OPN levels and brain grey and white matter volumes in patients with clinically isolated syndrome (CIS) suggestive of MS...
May 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28526444/the-development-of-a-novel-shade-selection-program-for-fixed-shade-translucent-dental-materials
#3
Melody N Carney, William M Johnston
OBJECTIVES: The objective of this study was to develop a shade selection program that predicts the shade choice with the smallest CIEDE2000 color difference for dental composite resin restorations when given a backing and target shade. By utilizing previously generated regression models, a database of spectral reflectance information, and principles of Kubelka-Munk layering, a highly accurate shade selection program was designed. METHODS: Using SAS 9.3 Statistical Analysis Software, a shade selection program was developed that incorporated Kubelka-Munk layering data of Herculite Ultra and Estelite Omega composite resins from a characterized database of absorption and scattering information...
May 16, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28525553/evaluation-of-conventional-and-frozen-elephant-trunk-techniques-on-spinal-cord-blood-flow-in-an-animal-model%C3%A2
#4
Sergey Leontyev, Maja-Theresa Dieterlen, Michelle Halling, Franziska Schlegel, Alexandro Hoyer, Susann Ossmann, Kerstin Klaeske, Christian D Etz, Friedrich W Mohr
OBJECTIVES: The treatment of patients with extensive thoracic aortic disease involving the arch and descending aorta is often performed using the frozen elephant trunk technique (FET). Spinal cord blood flow (SCBF) in cervical, thoracic and lumbar sections prior, during and after aortic arch surgery were compared in conventional elephant trunk (cET) and FET technique in a pig model. METHODS: German Landrace pigs (75-85 kg) underwent aortic arch surgery using the FET ( n  = 8) or cET ( n  = 8) techniques...
May 18, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28516870/the-relevance-of-cluster-analyses-to-stratify-systemic-lupus-erythematosus-increased-mortality-with-heavier-treatment
#5
Ginevra De Marchi, Luca Quartuccio, Francesca Zuliani, Milena Bond, Salvatore De Vita
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May 8, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28512546/evaluation-of-the-effect-of-different-enamel-surface-treatments-and-waiting-times-on-the-staining-prevention-after-bleaching
#6
Débora Monteiro, Allyson Moreira, Tulimar Cornacchia, Cláudia Magalhães
BACKGROUND: Bleached dental enamel can be more susceptible to staining than the enamel that has never been bleached, especially right after tooth bleaching. The aim of this study is to evaluate the effect of surface treatments and waiting time prior to contact with dye on bleached enamel staining susceptibility. MATERIAL AND METHODS: One hundred teeth were bleached with 35% hydrogen peroxide (Whiteness HP, FGM) and randomly assigned to G1 artificial saliva, G2 2% sodium fluoride (Flugel, Nova DFL), G3 casein phosphopeptide-amorphous calcium phosphate fluoride paste (CPP-ACPF, MI Paste Plus, GC America), G4 rinse for color maintenance after bleaching (Keep White Rinse, DMC) and G5 polishing with aluminum oxide-impregnated disks (Super Buff Disk, Shofu)...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28512252/epigenetic-regulation-of-zbtb18-promotes-glioblastoma-progression
#7
Vita Fedele, Fangping Dai, Anie Masilamani, Dieter Henrik Heiland, Eva Kling, Ana Gätjens-Sanchez, Roberto Ferrarese, Leonardo Platania, Soroush Doostkam, Hyunsoo Kim, Sven Nelander, Astrid Weyerbrock, Marco Prinz, Andrea Califano, Antonio Iavarone, Markus Bredel, Maria Stella Carro
Glioblastoma (GBM) is comprised of distinct subtypes characterized by their molecular profile. Mesenchymal identity in GBM has been associated with a comparatively unfavorable prognosis, primarily due to inherent resistance of these tumors to current therapies. The identification of molecular determinants of mesenchymal transformation could potentially allow for the discovery of new therapeutic targets. Zinc Finger and BTB Domain Containing 18 (ZBTB18/ZNF238/RP58) is a zinc finger transcriptional repressor with a crucial role in brain development and neuronal differentiation...
May 16, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28509651/the-concept-of-immunocompromised-district-might-explain-the-carcinogenic-progression-in-hidradenitis-suppurativa
#8
Valerio De Vita, Eleonora Ruocco
No abstract text is available yet for this article.
May 16, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28507188/cryoglobulinemia-in-sj%C3%A3-gren-syndrome-a-disease-subset-that-links-higher-systemic-disease-activity-autoimmunity-and-local-b-cell-proliferation-in-mucosa-associated-lymphoid-tissue
#9
Luca Quartuccio, Chiara Baldini, Roberta Priori, Elena Bartoloni, Francesco Carubbi, Alessia Alunno, Saviana Gandolfo, Serena Colafrancesco, Roberto Giacomelli, Roberto Gerli, Guido Valesini, Stefano Bombardieri, Salvatore De Vita
OBJECTIVE: To compare systemic disease activity by validated tools, i.e., the European League Against Rheumatism Sjögren Syndrome Disease Activity Index (ESSDAI) and the Clinical ESSDAI (ClinESSDAI) scores, between primary Sjögren syndrome (pSS) with positive serum cryoglobulins and pSS without serum cryoglobulins. METHODS: There were 825 consecutive patients with pSS who were retrospectively evaluated. RESULTS: The ESSDAI and the ClinESSDAI scores were significantly higher in cryoglobulin-positive patients (p < 0...
May 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28500244/tamoxifen-reduces-hepatic-vldl-production-and-gh-secretion-in-women-a-possible-mechanism-for-steatosis-development
#10
Vita Birzniece, P Hugh R Barrett, Ken K Y Ho
CONTEXT: Growth hormone (GH) stimulates hepatic synthesis of very-low-density lipoproteins (VLDL), whereas hepatic steatosis develops as a result of GH deficiency. Steatosis is also a complication of tamoxifen treatment, the cause of which is not known. As tamoxifen inhibits the secretion and action of GH, we hypothesize that it induces steatosis by inhibiting hepatic VLDL export. AIM: To investigate whether tamoxifen reduces hepatic VLDL secretion. DESIGN: Eight healthy, normolipidemic women (age 64...
May 12, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28495492/the-complex-relationship-between-self-reported-personal-recovery-and-clinical-recovery-in-schizophrenia
#11
Alessandro Rossi, Mario Amore, Silvana Galderisi, Paola Rocca, Alessandro Bertolino, Eugenio Aguglia, Giovanni Amodeo, Antonello Bellomo, Paola Bucci, Antonino Buzzanca, Bernardo Carpiniello, Anna Comparelli, Liliana Dell'Osso, Massimo di Giannantonio, Marina Mancini, Carlo Marchesi, Palmiero Monteleone, Cristiana Montemagni, Lucio Oldani, Rita Roncone, Alberto Siracusano, Paolo Stratta, Elena Tenconi, Annarita Vignapiano, Antonio Vita, Patrizia Zeppegno, Mario Maj
Self-reported 'personal recovery' and clinical recovery in schizophrenia (SRPR and CR, respectively) reflect different perspectives in schizophrenia outcome, not necessarily concordant with each other and usually representing the consumer's or the therapist's point of view. By means of a cluster analysis on SRPR-related variables, we identified three clusters. The first and third cluster included subjects with the best and the poorest clinical outcome respectively. The second cluster was characterized by better insight, higher levels of depression and stigma, lowest self-esteem and personal strength, and highest emotional coping...
May 8, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28492579/prevalence-and-factors-associated-with-problematic-internet-use-an-italian-survey-among-l%C3%A2-aquila-students
#12
Valeria Bianchini, Maria Rosita Cecilia, Rita Roncone, Vincenza Cofini
AIM: In this study we examined the prevalence of internet addiction (IA) and its associated factors in a sample of Italian students. MATERIALS AND METHODS: This is an observational study that involved 1403 students aged 15-24 and conducted in L’Aquila, Italy. 1129 students accepted to participate in our study and completed the Internet Addiction Test: 41% were male and the mean age of total sample was 19±2.8 years. RESULTS: The prevalence of “average user” was 51% (95% CI: 48-54)...
March 2017: Rivista di Psichiatria
https://www.readbyqxmd.com/read/28487415/randomized-comparison-of-helmet-cpap-versus-high-flow-nasal-cannula-oxygen-in-pediatric-respiratory-distress
#13
Giovanna Vitaliti, Maria Concetta Vitaliti, Maria Carla Finocchiaro, Vita Antonella Di Stefano, Piero Pavone, Nassim Matin, Nazgol Motamed-Gorji, Riccardo Lubrano, Raffaele Falsaperla
BACKGROUND: The current study aimed to compare the efficacy and safety of 2 noninvasive respiratory support methods, which included helmet CPAP and high-flow nasal cannula (HFNC) in children with respiratory distress admitted to a pediatric intermediate care unit. METHODS: This study was a prospective observational study conducted on children with respiratory distress (age 1-24 months) who were admitted to our acute and emergency operative unit. All included subjects were randomly treated with helmet CPAP or HFNC in a 1:1 fashion until their clinical picture, oxygen saturation, and arterial blood gas (ABG) parameters resolved...
May 9, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28483567/mathematical-model-for-isometric-and-isotonic-muscle-contractions
#14
R De Vita, R Grange, P Nardinocchi, L Teresi
A new mathematical model is presented to describe both the active and passive mechanics of muscles. In order to account for the active response, a two-layer kinematics that introduces both the visible and rest lengths of the muscle is presented within a rational mechanics framework. The formulation is based on an extended version of the principle of virtual power and the dissipation principle. By using an accurate constitutive description of muscle mobility under activation, details of microscopic processes that lead to muscle contraction are glossed over while macroscopic effects of chemical/electrical stimuli on muscle mechanics are retained...
May 5, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28480617/comparison-of-arterial-spin-labeling-registration-strategies-in-the-multi-center-genetic-frontotemporal-dementia-initiative-genfi
#15
Henri J M M Mutsaerts, Jan Petr, David L Thomas, Enrico de Vita, David M Cash, Matthias J P van Osch, Xavier Golay, Paul F C Groot, Sebastien Ourselin, John van Swieten, Robert Laforce, Fabrizio Tagliavini, Barbara Borroni, Daniela Galimberti, James B Rowe, Caroline Graff, Francesca B Pizzini, Elizabeth Finger, Sandro Sorbi, Miguel Castelo Branco, Jonathan D Rohrer, Mario Masellis, Bradley J MacIntosh
PURPOSE: To compare registration strategies to align arterial spin labeling (ASL) with 3D T1-weighted (T1w) images, with the goal of reducing the between-subject variability of cerebral blood flow (CBF) images. MATERIALS AND METHODS: Multi-center 3T ASL data were collected at eight sites with four different sequences in the multi-center GENetic Frontotemporal dementia Initiative (GENFI) study. In a total of 48 healthy controls, we compared the following image registration options: (I) which images to use for registration (perfusion-weighted images [PWI] to the segmented gray matter (GM) probability map (pGM) (CBF-pGM) or M0 to T1w (M0-T1w); (II) which transformation to use (rigid-body or non-rigid); and (III) whether to mask or not (no masking, M0-based FMRIB software library Brain Extraction Tool [BET] masking)...
May 8, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28467262/comparison-of-effectiveness-and-sensitivity-using-two-in-office-bleaching-protocols-for-a-6-hydrogen-peroxide-gel-in-a-randomized-clinical-trial
#16
P Vildósola, F Vera, J Ramírez, J Rencoret, H Pretel, O B Oliveira, M Tonetto, J Martín, E Fernández
OBJECTIVE: The aim of this blinded and randomized clinical trial was to compare two application protocols (one 36-minute application vs three 12-minute applications). We then assessed the effectiveness of the bleaching and any increase in sensitivity that was induced by bleaching via a split-mouth design. METHODS AND MATERIALS: Thirty patients were treated. One group had a half arch of teeth treated with a traditional application protocol (group A: 3 × 12 minutes for two sessions)...
May 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28466806/hcv-unrelated-cryoglobulinaemic-vasculitis-the-results-of-a-prospective-observational-study-by-the-italian-group-for-the-study-of-cryoglobulinaemias-gisc
#17
Massimo Galli, Letizia Oreni, Francesco Saccardo, Laura Castelnovo, Davide Filippini, Piero Marson, Maria Teresa Mascia, Cesare Mazzaro, Laura Origgi, Elena Ossi, Maurizio Pietrogrande, Piero Pioltelli, Luca Quartuccio, Salvatore Scarpato, Salvatore Sollima, Agostino Riva, Paolo Fraticelli, Roberta Zani, Dilia Giuggioli, Marco Sebastiani, Piercarlo Sarzi Puttini, Armando Gabrielli, Anna Linda Zignego, Patrizia Scaini, Clodoveo Ferri, Salvatore De Vita, Giuseppe Monti
OBJECTIVES: To investigate the clinical and laboratory patterns of HCV-unrelated cryoglobulinaemic vasculitis (CV), and the factors influencing its outcome. METHODS: Prospective study of all anti-HCV and HCV-RNA negative patients with CV who have been observed since January 2004 in 17 centres participating in the Italian Group for the Study of Cryoglobulinaemias (GISC). RESULTS: 175 enrolled were followed up for 677 person-years. The associated conditions were primary Sjögren's syndrome (21...
March 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28461047/influence-of-cement-type-and-ceramic-primer-on-retention-of-polymer-infiltrated-ceramic-crowns-to-a-one-piece-zirconia-implant
#18
Nadja Rohr, Stefan Brunner, Sabrina Märtin, Jens Fischer
STATEMENT OF PROBLEM: The best procedure for cementing a restoration to zirconia implants has not yet been established. PURPOSE: The purpose of this in vitro study was to measure the retention of polymer-infiltrated ceramic crowns to zirconia 1-piece implants using a wide range of cements. The effect of ceramic primer treatment on the retention force was also recorded. The retention results were correlated with the shear bond strength of the cement to zirconia and the indirect tensile strength of the cements to better understand the retention mechanism...
April 28, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28458403/mindfulness-goes-to-school-things-learned-so-far-from-research-and-real-world-experiences
#19
Randye J Semple, Vita Droutman, Brittany Ann Reid
Mindfulness-based curricula are being implemented in K-12 schools across the nation. Many of these programs, although well-considered and implemented, have little or no research support for their effectiveness. Recognizing the paucity of published research in this area, a sampling of school-based programs currently being implemented in the schools is reviewed. The programs reviewed are Inner Explorer, Master Mind and Moment Program, Mindfulness and Mind-Body Skills for Children, Mindful Schools, Resilient Kids, Still Quiet Place, Stress Reduction and Mindfulness Curriculum and Mindful Moment, and Wellness and Resilience Program...
January 2017: Psychology in the Schools
https://www.readbyqxmd.com/read/28453019/site-accessibility-tailors-dna-cleavage-by-restriction-enzymes-in-dna-confined-monolayers
#20
Chiara Rotella, Giovanni Doni, Alessandro Bosco, Matteo Castronovo, Alessandro De Vita, Loredana Casalis, Giovanni M Pavan, Pietro Parisse
Density-tunable nanografted monolayers (NAMs) of short oligonucleotide sequences on gold surfaces show novel properties that make them suitable for advanced biosensing applications, and in particular to study the effects of crowding and confinement on biomolecular interactions. Here, combining atomic force microscopy nanolithography, topography measurements and coarse-grained molecular dynamics simulations, we investigated restriction enzyme reaction mechanisms within confined DNA brushes highlighting the role played by the DNA sequence conformation and restriction site position along the chain, respectively, in determining the accessibility of the enzyme, and its consequent cleavage efficiency...
May 18, 2017: Nanoscale
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